Bicycle Therapeutics (BCYC)

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	891.41 mm	891.41 mm	891.41 mm	891.41 mm	891.41 mm	891.41 mm
Cash burn (monthly)	23.50 mm	(no burn)	21.28 mm	16.37 mm	13.28 mm	16.88 mm
Cash used (since last report)	103.98 mm	n/a	94.16 mm	72.43 mm	58.75 mm	74.71 mm
Cash remaining	787.43 mm	n/a	797.25 mm	818.98 mm	832.66 mm	816.70 mm
Runway (months of cash)	33.5	n/a	37.5	50.0	62.7	48.4

Beta Read what these cash burn values mean

Financial data from company earnings reports.

Institutional ownership, Q3 2024

BCYC institutional ownership history Ownership history

65.2% owned by funds/institutions

13F holders	Current	Prev Q	Change
Total holders	110	111	-0.9%
Opened positions	18	27	-33.3%
Closed positions	19	12	+58.3%
Increased positions	35	34	+2.9%
Reduced positions	32	25	+28.0%

13F shares	Current	Prev Q	Change
Total value	825.40 bn	741.37 bn	+11.3%
Total shares	45.03 mm	44.31 mm	+1.6%
Total puts	24.60 k	12.40 k	+98.4%
Total calls	39.60 k	3.40 k	+1064.7%
Total put/call ratio	0.6	3.6	-83.0%

Largest owners	Shares	Value	Change
Baker Bros. Advisors	9.40 mm	$212.72 bn	0.0%
Deep Track Capital	3.55 mm	$80.29 bn	+1.6%
FCPM Iii Services B.V.	2.34 mm	$52.95 bn	+10.2%
Ra Capital Management	2.25 mm	$50.99 bn	0.0%
Armistice Capital	1.96 mm	$44.26 bn	-0.8%
Westfield Capital Management	1.85 mm	$41.89 bn	+21.5%
T. Rowe Price	1.72 mm	$38.97 mm	+115.7%
SVLSF V	1.56 mm	$54.41 mm	0.0%
GSK GSK	1.53 mm	$39.40 mm	0.0%
Tybourne Capital Management	1.39 mm	$31.56 bn	-7.6%

Largest transactions	Shares	Bought/sold	Change
Fairmount Funds Management	123.54 k	-945.66 k	-88.4%
T. Rowe Price	1.72 mm	+923.54 k	+115.7%
Point72 Asset Management	899.80 k	+841.30 k	+1438.1%
Avoro Capital Advisors	0.00	-700.00 k	EXIT
Woodline Partners	0.00	-586.62 k	EXIT
Logos Global Management	500.00 k	+500.00 k	NEW
PFG Principal Financial	443.14 k	+443.14 k	NEW
BlackRock	419.76 k	+419.76 k	NEW
First Light Asset Management	967.01 k	-417.76 k	-30.2%
BLK BlackRock	0.00	-402.22 k	EXIT

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

BCYC insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
3 Jan 25	Nigel Crockett	Ordinary Shares	Sell	Dispose S	No	No	14.75	936	13.81 k	51,053
3 Jan 25	Alistair Milnes	Ordinary Shares	Sell	Dispose S	No	No	14.75	936	13.81 k	99,788
2 Jan 25	Baker Bros. Advisors	American Depositary Shares	Grant	Acquire A	Yes	No	0	4,400	0.00	9,999,674
2 Jan 25	Baker Bros. Advisors	American Depositary Shares	Grant	Acquire A	Yes	No	0	4,400	0.00	918,483
2 Jan 25	Baker Bros. Advisors	Share Option [object Object]	Grant	Acquire A	Yes	No	14	8,801	123.21 k	8,801
2 Jan 25	Baker Bros. Advisors	Share Option [object Object]	Grant	Acquire A	Yes	No	14	8,801	123.21 k	8,801
2 Jan 25	Legault Pierre	Ordinary Shares	Grant	Acquire A	No	No	0	12,500	0.00	46,000
2 Jan 25	Legault Pierre	Stock Option Ordinary Shares	Grant	Acquire A	No	No	14	25,000	350.00 k	25,000
2 Jan 25	Nigel Crockett	Ordinary Shares	Sell	Dispose S	No	No	14.09	2,583	36.39 k	51,989
2 Jan 25	Nigel Crockett	Ordinary Shares	Grant	Acquire A	No	No	0	8,750	0.00	54,572