Dyne Therapeutics (DYN)

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	575.63 mm	575.63 mm	575.63 mm	575.63 mm	575.63 mm	575.63 mm
Cash burn (monthly)	(no burn)	(no burn)	37.96 mm	37.43 mm	30.26 mm	31.31 mm
Cash used (since last report)	n/a	n/a	163.02 mm	160.72 mm	129.93 mm	134.44 mm
Cash remaining	n/a	n/a	412.61 mm	414.90 mm	445.69 mm	441.18 mm
Runway (months of cash)	n/a	n/a	10.9	11.1	14.7	14.1

Beta Read what these cash burn values mean

Financial data from company earnings reports.

Institutional ownership, Q4 2024

DYN institutional ownership history Ownership history

79.6% owned by funds/institutions

13F holders	Current	Prev Q	Change
Total holders	203	205	-1.0%
Opened positions	37	45	-17.8%
Closed positions	39	36	+8.3%
Increased positions	67	73	-8.2%
Reduced positions	62	55	+12.7%

13F shares	Current	Prev Q	Change
Total value	2.56 tn	3.91 tn	-34.4%
Total shares	128.76 mm	129.18 mm	-0.3%
Total puts	434.50 k	238.10 k	+82.5%
Total calls	135.10 k	234.00 k	-42.3%
Total put/call ratio	3.2	1.0	+216.1%

Largest owners	Shares	Value	Change
Atlas Venture Life Science Advisors	8.02 mm	$188.94 bn	-0.0%
FMR	8.00 mm	$188.41 bn	-11.4%
BLK BlackRock	7.95 mm	$187.29 bn	+2.0%
JHG Janus Henderson	7.38 mm	$173.81 bn	+8.3%
Vanguard	6.70 mm	$157.94 bn	-2.3%
Ra Capital Management	6.38 mm	$150.34 bn	0.0%
Capital Fund IV Cooperatief U.A. Forbion	5.80 mm	$169.23 mm	0.0%
Atlas Venture Fund XI	5.71 mm	$166.85 mm	0.0%
FCPM Iii Services B.V.	5.46 mm	$128.70 bn	-8.3%
RTW Investments	5.22 mm	$122.95 bn	-23.5%

Largest transactions	Shares	Bought/sold	Change
JEF Jefferies Financial	1.80 mm	+1.80 mm	NEW
RTW Investments	5.22 mm	-1.60 mm	-23.5%
Deep Track Capital	2.00 mm	-1.28 mm	-39.1%
FMR	8.00 mm	-1.03 mm	-11.4%
Norges Bank	950.10 k	+950.10 k	NEW
First Light Asset Management	420.43 k	-836.85 k	-66.6%
Point72 Asset Management	924.68 k	+822.20 k	+802.3%
Braidwell	681.18 k	+681.18 k	NEW
Avoro Capital Advisors	0.00	-650.00 k	EXIT
JHG Janus Henderson	7.38 mm	+566.15 k	+8.3%

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

DYN insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
22 Dec 25	Karnani Vikram	Stock option Common Stock	Grant	Acquire A	No	No	20.78	59,665	1.24 mm	59,665
5 Dec 25	Douglas Kerr	Common Stock	Sell	Dispose S	No	Yes	20.72	880	18.23 k	87,510
5 Dec 25	Johanna Friedl-Naderer	Common Stock	Sell	Dispose S	No	Yes	20.72	144	2.98 k	94,729
5 Dec 25	John Cox	Common Stock	Sell	Dispose S	No	No	20.72	2,662	55.16 k	196,877

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.