Science 37 (SNCE)

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	56.41 mm	56.41 mm	56.41 mm	56.41 mm	56.41 mm	56.41 mm
Cash burn (monthly)	2.87 mm	6.15 mm	4.85 mm	10.80 mm	133.33 k	4.02 mm
Cash used (since last report)	48.89 mm	104.98 mm	82.72 mm	184.23 mm	2.28 mm	68.52 mm
Cash remaining	7.52 mm	-48.58 mm	-26.31 mm	-127.82 mm	54.13 mm	-12.12 mm
Runway (months of cash)	2.6	-7.9	-5.4	-11.8	406.0	-3.0

Beta Read what these cash burn values mean

Financial data from Science 37 earnings reports.

Institutional ownership, Q4 2023

SNCE institutional ownership history Ownership history

13F holders	Current	Prev Q	Change
Total holders	6	48	-87.5%
Opened positions	1	8	-87.5%
Closed positions	43	13	+230.8%
Increased positions	0	8	EXIT
Reduced positions	1	7	-85.7%

13F shares	Current	Prev Q	Change
Total value	421.63 mm	19.03 bn	-97.8%
Total shares	51.96 mm	99.41 mm	-47.7%
Total puts	0.00	0.00
Total calls	0.00	0.00
Total put/call ratio	–	–	–

Largest owners	Shares	Value	Change
TMO Thermo Fisher Scientific	17.38 mm	$191.70 mm	0.0%
PPD PPD	17.38 mm	$0.00	0.0%
Lux Capital Management	12.25 mm	$69.33 mm	0.0%
LifeSci	4.92 mm	$0.00	0.0%
Kingswood Wealth Advisors	29.73 k	$158.73 mm	NEW
M&R Capital Management	350.00	$1.87 mm	-95.0%

Largest transactions	Bought/sold	Change
Redmile	-19.81 mm	EXIT
Russell Investments	-3.96 mm	EXIT
GLYNN Capital Management	-3.54 mm	EXIT
Vanguard	-3.23 mm	EXIT
GOOG Alphabet	-3.21 mm	EXIT
MIC Capital Management UK	-2.35 mm	EXIT
Alyeska Investment	-1.77 mm	EXIT
Boston Partners	-1.42 mm	EXIT
Citadel Advisors	-1.42 mm	EXIT
Kent Lake Capital	-1.08 mm	EXIT

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

SNCE insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value
12 Mar 24	Christine A Pellizzari	Common Stock	Sale back to company	Dispose D	No	No	5.75	35,115	201.91 k
12 Mar 24	Christine A Pellizzari	Common Stock		Dispose U	No	No	5.75	14,579	83.83 k
12 Mar 24	Christine A Pellizzari	Earn-Out Right Common Stock	Sale back to company	Dispose D	No	No	0	428	0.00
12 Mar 24	Christine A Pellizzari	RSU Common Stock	Sale back to company	Dispose D	No	No	0	37,222	0.00
12 Mar 24	David Coman	Common Stock	Sale back to company	Dispose D	No	No	5.75	30,781	176.99 k
12 Mar 24	David Coman	Common Stock		Dispose U	No	No	5.75	53,834	309.55 k
12 Mar 24	David Coman	Stock Option Common Stock	Sale back to company	Dispose D	No	No	5.6	192,427	1.08 mm
12 Mar 24	David Coman	Earn-Out Right Common Stock	Sale back to company	Dispose D	No	No	0	28,899	0.00
12 Mar 24	David Coman	RSU Common Stock	Sale back to company	Dispose D	No	No	0	49,512	0.00
12 Mar 24	Autenried Paul von	Common Stock		Dispose U	No	No	5.75	2,302	13.24 k

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.

Press releases

From Benzinga Pro

Science 37 Appoints Tyler Van Horn as CEO to Lead Next Era of Patient-Access Innovation

14 Jan 25

MORRISVILLE, N.C., Jan. 14, 2025 (GLOBE NEWSWIRE) -- Science 37, a leader in enhancing patient access to clinical trials, announces the appointment of Tyler Van Horn as Chief Executive Officer. Formerly the company's