| Quarter (USD) | Sep 24 | Jun 24 | Mar 24 | Dec 23 | |
|---|---|---|---|---|---|
| Revenue | |||||
| Cost of revenue | |||||
| Operating income | |||||
| Operating margin | |||||
| Net income | |||||
| Net profit margin | |||||
| Cash on hand | |||||
| Change in cash | |||||
| Diluted EPS |
| Annual (USD) | Dec 23 | Dec 22 | Dec 21 | Dec 20 | |
|---|---|---|---|---|---|
| Revenue | |||||
| Cost of revenue | |||||
| Operating income | |||||
| Operating margin | |||||
| Net income | |||||
| Net profit margin | |||||
| Cash on hand | |||||
| Change in cash | |||||
| Diluted EPS |
| Cash burn rate (est.) | Burn method: Change in cash | Burn method: Operating income | Burn method: FCF (opex + capex) | Last Q | Avg 4Q | Last Q | Avg 4Q | Last Q | Avg 4Q |
|---|---|---|---|---|---|---|
| Cash on hand (at last report) | 270.14 mm | 270.14 mm | 270.14 mm | 270.14 mm | 270.14 mm | 270.14 mm |
| Cash burn (monthly) | (no burn) | (no burn) | 8.31 mm | 8.33 mm | 5.49 mm | 6.23 mm |
| Cash used (since last report) | n/a | n/a | 29.22 mm | 29.28 mm | 19.28 mm | 21.89 mm |
| Cash remaining | n/a | n/a | 240.92 mm | 240.85 mm | 250.86 mm | 248.24 mm |
| Runway (months of cash) | n/a | n/a | 29.0 | 28.9 | 45.7 | 39.9 |
| 13F holders | Current |
|---|---|
| Total holders | 163 |
| Opened positions | 55 |
| Closed positions | 25 |
| Increased positions | 52 |
| Reduced positions | 39 |
| 13F shares | Current |
|---|---|
| Total value | 635.02 bn |
| Total shares | 103.58 mm |
| Total puts | 454.10 k |
| Total calls | 580.00 k |
| Total put/call ratio | 0.8 |
| Largest owners | Shares | Value |
|---|---|---|
| Orbimed Advisors | 7.56 mm | $63.08 bn |
| Vivo Capital | 6.90 mm | $57.51 bn |
| Soleus Capital Management | 6.22 mm | $51.90 bn |
| Soleus Capital Master Fund | 6.22 mm | $42.88 mm |
| Deep Track Capital | 5.58 mm | $46.51 bn |
| BlackRock | 4.70 mm | $39.19 bn |
| Vivo Capital Fund VIII | 4.60 mm | $31.68 mm |
| Vivo Capital VIII | 4.34 mm | $0.00 |
| Citadel Advisors | 3.67 mm | $30.63 bn |
| Venrock Healthcare Capital Partners III | 3.52 mm | $24.23 mm |
| Date | Owner | Security | Transaction | Code | Indirect | 10b5-1 | $Price | #Shares | $Value | #Remaining |
|---|---|---|---|---|---|---|---|---|---|---|
| 6 Jan 25 | Mark J. Vignola | Common Stock | Sell | Dispose S | No | Yes | 5.7953 | 9,059 | 52.50 k | 74,752 |
| 6 Jan 25 | Jill M. Quigley | Common Stock | Sell | Dispose S | No | Yes | 5.7943 | 8,760 | 50.76 k | 0 |
| 2 Jan 25 | Emil Kuriakose | Common Stock | Sell | Dispose S | No | No | 5.7146 | 4,481 | 25.61 k | 54,269 |
| 2 Jan 25 | Mark J. Vignola | Common Stock | Sell | Dispose S | No | No | 5.7232 | 8,129 | 46.52 k | 83,811 |
| 2 Jan 25 | Jill M. Quigley | Common Stock | Sell | Dispose S | No | No | 5.7215 | 6,240 | 35.70 k | 8,760 |
| 12 Dec 24 | Emil Kuriakose | Stock Option Common Stock | Grant | Acquire A | No | No | 6.59 | 120,000 | 790.80 k | 120,000 |
| 5 Dec 24 | Amy L. Burroughs | Common Stock | Buy | Acquire P | No | No | 7.15 | 15,450 | 110.47 k | 19,099 |
