Arrowhead Pharmaceuticals (ARWR)

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	102.69 mm	102.69 mm	102.69 mm	102.69 mm	102.69 mm	102.69 mm
Cash burn (monthly)	(no burn)	683.83 k	57.60 mm	51.22 mm	45.74 mm	38.57 mm
Cash used (since last report)	n/a	2.75 mm	231.66 mm	206.00 mm	183.96 mm	155.13 mm
Cash remaining	n/a	99.93 mm	-128.97 mm	-103.31 mm	-81.27 mm	-52.44 mm
Runway (months of cash)	n/a	146.1	-2.2	-2.0	-1.8	-1.4

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Financial data from company earnings reports.

Institutional ownership, Q3 2024

ARWR institutional ownership history Ownership history

77.0% owned by funds/institutions

13F holders	Current	Prev Q	Change
Total holders	270	271	-0.4%
Opened positions	36	39	-7.7%
Closed positions	37	38	-2.6%
Increased positions	89	92	-3.3%
Reduced positions	88	85	+3.5%

13F shares	Current	Prev Q	Change
Total value	1.76 tn	2.45 tn	-28.0%
Total shares	95.76 mm	97.80 mm	-2.1%
Total puts	423.10 k	546.70 k	-22.6%
Total calls	152.00 k	1.32 mm	-88.5%
Total put/call ratio	2.8	0.4	+574.5%

Largest owners	Shares	Value	Change
BlackRock	15.84 mm	$306.74 bn	NEW
Vanguard	12.23 mm	$236.88 bn	+0.1%
Avoro Capital Advisors	8.89 mm	$172.18 bn	0.0%
STT State Street	6.35 mm	$123.08 bn	+8.8%
FMR	6.07 mm	$117.53 bn	-10.9%
Slate Path Capital	4.89 mm	$94.62 bn	+18.0%
T. Rowe Price Investment Management	3.57 mm	$69.24 mm	+39.6%
Geode Capital Management	2.96 mm	$57.43 bn	+0.9%
Siren, L.L.C.	2.46 mm	$47.63 bn	NEW
Ubs Global Asset Management Americas	2.15 mm	$41.73 bn	-5.9%

Largest transactions	Shares	Bought/sold	Change
BlackRock	15.84 mm	+15.84 mm	NEW
BLK BlackRock	0.00	-15.68 mm	EXIT
Artal	0.00	-3.19 mm	EXIT
Siren, L.L.C.	2.46 mm	+2.46 mm	NEW
Norges Bank	0.00	-1.59 mm	EXIT
T. Rowe Price Investment Management	3.57 mm	+1.01 mm	+39.6%
Rokos Capital Management	0.00	-939.98 k	EXIT
Slate Path Capital	4.89 mm	+746.00 k	+18.0%
FMR	6.07 mm	-744.66 k	-10.9%
Pictet Asset Management Holding	14.21 k	-729.47 k	-98.1%

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

ARWR insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
23 Jan 25	Olukotun Adeoye Y	Common Stock	Sell	Dispose S	No	Yes	21	959	20.14 k	35,781
7 Jan 25	Patrick O'Brien	Common Stock	Sell	Dispose S	No	Yes	19.69	8,000	157.52 k	527,201
7 Jan 25	Kenneth Allen Myszkowski	Common Stock	Sell	Dispose S	No	No	19.69	10,000	196.90 k	455,433
7 Jan 25	Kenneth Allen Myszkowski	Common Stock	Sell	Dispose S	No	Yes	19.7	8,000	157.60 k	465,433
6 Jan 25	Patrick O'Brien	Common Stock	Sell	Dispose S	No	Yes	20.1	9,526	191.47 k	535,201
6 Jan 25	Patrick O'Brien	Common Stock	Sell	Dispose S	No	Yes	19.69	19,658	387.07 k	544,727
6 Jan 25	James C Hamilton	Common Stock	Sell	Dispose S	No	Yes	20.11	10,971	220.63 k	272,122
6 Jan 25	James C Hamilton	Common Stock	Sell	Dispose S	No	Yes	19.68	21,758	428.20 k	283,093
6 Jan 25	Kenneth Allen Myszkowski	Common Stock	Sell	Dispose S	No	Yes	20.1	9,402	188.98 k	473,433
6 Jan 25	Kenneth Allen Myszkowski	Common Stock	Sell	Dispose S	No	Yes	19.68	17,765	349.62 k	482,835