OPKO Health (OPK)

OPKO Instrumentation, LLC • OPKO Pharmaceuticals, LLC • OPKO Diagnostics, LLC • ModeX Therapeutics, Inc. • OPKO Chile, S.A. • Arama Natural Products Distribuidora, Ltda • Pharmacos Exakta S.A. de C.V. • FineTech Pharmaceutical Ltd • OPKO Health Europe, S.L. • OPKO Biologics, Ltd ...

IRS number

752402409

OPK stock data

1M 3M 6M 1Y

Analyst ratings and price targets

Last 3 months

Average target

$2.63

Low target

$2.25

High target

$3.00

Latest filings (excl ownership)

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8-K

OPKO Health Reports Fourth Quarter 2024 Business Highlights and Financial Results

27 Feb 25

8-K

Regulation FD Disclosure

7 Nov 24

OPKO Health Reports Third Quarter 2024 Business Highlights and Financial Results

7 Nov 24

8-K

Labcorp Completes Acquisition of Select Assets of BioReference Health's Diagnostics Business

7 Aug 24

OPKO Health Reports Second Quarter 2024 Business Highlights and Financial Results

7 Aug 24

8-K

Departure of Directors or Certain Officers

26 Jul 24

8-K

OPKO Health and HealthCare Royalty Enter into $250 Million Note Purchase Agreement Secured by NGENLA’s Profit Share Payments

17 Jul 24

Transcripts

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OPK

Earnings call transcript

2024 Q4

27 Feb 25

OPK

Earnings call transcript

2024 Q3

7 Nov 24

OPK

Earnings call transcript

2024 Q2

7 Aug 24

OPK

Earnings call transcript

2024 Q1

7 May 24

OPK

Earnings call transcript

2023 Q4

27 Feb 24

OPK

Earnings call transcript

2023 Q3

6 Nov 23

OPK

Earnings call transcript

2023 Q2

3 Aug 23

OPK

Earnings call transcript

2023 Q2

3 Aug 23

OPK

Earnings call transcript

2023 Q1

3 May 23

OPK

Earnings call transcript

2022 Q4

23 Feb 23

Latest ownership filings

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PHILLIP MD ET AL FROST

28 Feb 25

PHILLIP MD ET AL FROST

28 Jan 25

PHILLIP MD ET AL FROST

17 Jan 25

PHILLIP MD ET AL FROST

15 Jan 25

PHILLIP MD ET AL FROST

13 Dec 24

PHILLIP MD ET AL FROST

11 Dec 24

PHILLIP MD ET AL FROST

29 Nov 24

PHILLIP MD ET AL FROST

22 Nov 24

SC 13D/A

GeneDx Holdings Corp.

20 Nov 24

4/A

PHILLIP MD ET AL FROST

20 Nov 24

Financial summary

Financial statements Chart OPK financial data

Quarter (USD)	Sep 24	Jun 24	Mar 24	Dec 23
Revenue
Cost of revenue
Operating income
Operating margin
Net income
Net profit margin
Cash on hand
Change in cash
Diluted EPS

Annual (USD)	Dec 23	Dec 22	Dec 21	Dec 20
Revenue
Cost of revenue
Operating income
Operating margin
Net income
Net profit margin
Cash on hand
Change in cash
Diluted EPS

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	420.07 mm	420.07 mm	420.07 mm	420.07 mm	420.07 mm	420.07 mm
Cash burn (monthly)	(no burn)	(no burn)	(no burn)	15.66 mm	5.19 mm	9.66 mm
Cash used (since last report)	n/a	n/a	n/a	79.60 mm	26.37 mm	49.06 mm
Cash remaining	n/a	n/a	n/a	340.47 mm	393.69 mm	371.00 mm
Runway (months of cash)	n/a	n/a	n/a	21.7	75.9	38.4

Beta Read what these cash burn values mean

Financial data from OPKO Health earnings reports.

Institutional ownership, Q4 2024

OPK institutional ownership history Ownership history

66.4% owned by funds/institutions

13F holders	Current	Prev Q	Change
Total holders	235	240	-2.1%
Opened positions	34	37	-8.1%
Closed positions	39	32	+21.9%
Increased positions	66	56	+17.9%
Reduced positions	60	62	-3.2%

13F shares	Current	Prev Q	Change
Total value	279.65 bn	272.18 bn	+2.7%
Total shares	453.41 mm	441.57 mm	+2.7%
Total puts	9.18 mm	10.09 mm	-9.0%
Total calls	3.58 mm	6.03 mm	-40.7%
Total put/call ratio	2.6	1.7	+53.4%

Largest owners	Shares	Value	Change
Phillip MD Frost Et Al	211.61 mm	$351.28 mm	+0.2%
Rubric Capital Management	48.71 mm	$71.60 bn	0.0%
Vanguard	29.21 mm	$42.93 bn	-0.0%
BlackRock	28.17 mm	$41.41 bn	-1.5%
Gary J. Nabel	19.86 mm	$48.45 mm	0.0%
Zerhouni Elias A.	19.78 mm	$48.26 mm	0.0%
STT State Street	9.07 mm	$13.34 bn	+4.1%
Geode Capital Management	8.39 mm	$12.33 bn	+0.1%
Hsiao Jane PH D	5.13 mm	$5.18 mm	0.0%
UBS UBS	4.82 mm	$7.09 bn	+469.8%

Largest transactions	Shares	Bought/sold	Change
IVZ Invesco	1.55 mm	-4.48 mm	-74.2%
UBS UBS	4.82 mm	+3.98 mm	+469.8%
Jane Street	2.81 mm	+2.28 mm	+429.1%
Millennium Management	4.59 mm	+2.11 mm	+85.3%
MS Morgan Stanley	3.17 mm	+1.84 mm	+138.3%
Lazard Asset Management	2.55 mm	+1.50 mm	+143.6%
Altshuler Shaham	1.41 mm	+1.41 mm	NEW
Norges Bank	1.13 mm	+1.13 mm	NEW
GS The Goldman Sachs Group, Inc.	3.84 mm	+1.10 mm	+40.0%
Gsa Capital Partners	1.08 mm	+1.08 mm	NEW

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

OPK insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
28 Feb 25	Phillip MD Frost Et Al	Common Stock	Buy	Acquire P	Yes	No	1.71	67,434	115.31 k	213,301,448
28 Jan 25	Phillip MD Frost Et Al	Common Stock	Buy	Acquire P	Yes	No	1.4738	47,537	70.06 k	213,234,014
17 Jan 25	Phillip MD Frost Et Al	Common Stock	Buy	Acquire P	Yes	No	1.4695	150,000	220.43 k	213,186,477
15 Jan 25	Phillip MD Frost Et Al	Common Stock	Buy	Acquire P	Yes	No	1.4817	500,000	740.85 k	213,036,477
13 Dec 24	Phillip MD Frost Et Al	Common Stock	Buy	Acquire P	Yes	No	1.595	125,000	199.38 k	212,536,477