EXHIBIT 32.1
CERTIFICATION
OF
CHIEF EXECUTIVE OFFICER AND CHIEF FINANCIAL OFFICER
Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, each of the undersigned officers of Manhattan Pharmaceuticals, Inc. do hereby certify that:
(a) the Quarterly Report on Form 10-QSB of Manhattan Pharmaceuticals, Inc. for the quarter ended September 30, 2003 (the “Report:) fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and
(b) information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of Manhattan Pharmaceuticals, Inc.
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| Date: August 16, 2004 | By: | /s/ Leonard Firestone |
| Leonard Firestone President and Chief Executive Officer | ||
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| Date: August 16, 2004 | By: | /s/ Nicholas J. Rossettos |
| Nicholas J. Rossettos Chief Financial Officer and Chief Operating Officer | ||