Seelos Therapeutics (SEELQ) S-4 Registration of securities issued in business combination transactions

Exhibit 99.4

August 29, 2018

Apricus Biosciences, Inc.

11975 El Camino Real, Suite 300

San Diego, CA 92130

Consent to Reference in Proxy Statement/Prospectus/Information Statement

Apricus Biosciences, (the "Company") is filing a Registration Statement on Form S-4 (Registration No. 333-    ) with the Securities and Exchange Commission under the Securities Act of 1933, as amended (the "Securities Act"). In connection therewith, I hereby consent, pursuant to Rule 438 of the Securities Act, to the reference to me in the proxy statement/prospectus/information statement included in such registration statement as a future member of the board of directors of the Company.

Sincerely,

/s/ Brian Lian

Brian Lian, Ph.D.