Exhibit 99.1
FOR IMMEDIATE RELEASE
INTROGEN THERAPEUTICS REPORTS FOURTH QUARTER 2004 AND ANNUAL
FINANCIAL RESULTS
Results in Line with Expectations
AUSTIN, TX, March 14, 2005— Introgen Therapeutics, Inc. (NASDAQ: INGN) announced today its results for the quarter and year ended December 31, 2004, reporting progress during these periods in its research and development programs, clinical trial programs and regulatory milestones.
Introgen reported a net loss of $4.4 million, or $0.16 per share, for the quarter ended December 31, 2004. These results compare to a net loss of $7.0 million, or $0.26 per share, for the previous quarter ended September 30, 2004 and a net loss of $5.4 million, or $0.21 per share, for the comparable prior year quarter ended December 31, 2003.
During the quarter ended December 31, 2004, cash, cash equivalents and short-term investments increased $17.4 million as a result of net proceeds of $22.9 million from the sale of common stock during the quarter, offset by $5.7 million used to fund operations during the quarter. At December 31, 2004, Introgen had cash, cash equivalents and short-term investments of $38.2 million.
Revenue was $1.2 million for the quarter ended December 31, 2004, compared to revenue of $2,000 for the quarter ended December 31, 2003. Operating expenses were $5.8 million for the quarter ended December 31, 2004, compared to $7.4 million for the quarter ended September 30, 2004 and $5.6 million for the quarter ended December 31, 2003.
For the year ended December 31, 2004, Introgen reported a net loss of $24.4 million, or $0.91 per share, compared to a net loss for the year ended December 31, 2003 of $19.3 million, or $0.84 per share. Revenue for the year ended December 31, 2004 was $1.8 million, compared to revenue for the year ended December 31, 2003 of $0.3 million. Operating expenses were $27.1 million for the year ended December 31, 2004 compared to $21.1 million for the year ended December 31, 2003.
Quarterly Conference Call
Introgen has scheduled a conference call to discuss the financial results at 4:30 p.m. EST today. Interested parties can access a live Internet broadcast at www.introgen.com. For those unable to listen to the broadcast the call will be archived at Introgen’s Website at www.introgen.com in the Investor Relations section.
Introgen is a leading developer of biopharmaceutical products designed to induce therapeutic protein expression using non-integrating gene agents for the treatment of cancer and other diseases. Introgen maintains integrated research, development, manufacturing, clinical and regulatory departments and operates a commercial-scale, CGMP manufacturing facility.
Certain statements in this press release that are not strictly historical may be “forward-looking” statements, which are based on current expectations and entail various risks and uncertainties. Such forward-looking statements
include, but are not limited to, those relating to Introgen’s future success with its clinical development program for treatment of cancer or other diseases. There can be no assurance that Introgen will be able to commercially develop gene-based drugs, that necessary regulatory approvals will be obtained or that any clinical trials or studies undertaken will be successful or that the proposed treatments will prove to be safe and/or effective. The actual results may differ from those described in this press release due to risks and uncertainties that exist in Introgen’s operations and business environment, including, but without limitation, Introgen’s stage of product development and the limited experience in the development of gene-based drugs in general, Introgen’s dependence upon proprietary technology and current competition, history of operating losses and accumulated deficits, reliance on collaborative relationships, and uncertainties related to clinical trials, the safety and efficacy of Introgen’s product candidates, the ability to obtain the appropriate regulatory approvals, patent protection and market acceptance, as well as other risks detailed from time to time in Introgen’s filings with the Securities and Exchange Commission. Introgen undertakes no obligation to publicly release the results of any revisions to any forward-looking statements that reflect events or circumstances arising after the date hereof.
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Editor’s Note: For more information on Introgen Therapeutics, or for a menu of archived press releases, please visit Introgen’s Website at www.introgen.com.
Contact:
Introgen Therapeutics, Inc.
C. Channing Burke
(512) 708 9310 Ext. 322
Email: c.burke@introgen.com
