Rockwell Medical (RMTI) S-8 Registration of securities for employees

EXHIBIT 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation by reference in this Registration Statement of Rockwell Medical Technologies, Inc. on Form S-8 of our report dated March 23, 2007 on the consolidated financial statements of Rockwell Medical Technologies, Inc., appearing in the Annual Report on Form 10-KSB of Rockwell Medical Technologies, Inc. as of and for the years ended December 31, 2006 and 2005.

/s/ PLANTE & MORAN, PLLC

Auburn Hills, Michigan

October 18, 2007