Exhibit 1
JOINT FILING AGREEMENT
The undersigned hereby agree that the Statement on Schedule 13D, dated September 9, 2019, with respect to the ordinary shares of Avedro, Inc. is filed on behalf of each of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended. Each of the undersigned agrees to be responsible for the timely filing of this Statement, and for the completeness and accuracy of the information concerning itself contained therein. This Agreement may be executed in any number of counterparts, all of which taken together shall constitute one and the same instrument.
IN WITNESS WHEREOF, the undersigned have executed this Agreement as of the 9th day of September 2019.
| ORBIMED ADVISORS LLC | |||
| By: | /s/ Carl Gordon | ||
| Name: Carl Gordon | |||
| Title: Member of OrbiMed Advisors LLC | |||
ORBIMED ROF II LLC
| |||
By: | ORBIMED ADVISORS LLC, its managing member | ||
| By: | /s/ Carl Gordon | ||
| Name: Carl Gordon | |||
| Title: Member | |||
| ORBIMED CAPITAL GP VI LLC | |||
| By: | ORBIMED ADVISORS LLC, its managing member | ||
| By: | /s/ Carl Gordon | ||
| Carl Gordon | |||
| Member of OrbiMed Advisors LLC | |||
