Seagen (SGEN) 10-K/A 2009 FY Annual report (amended)

Exhibit 31.4

CERTIFICATIONS

I, Todd E. Simpson, certify that:

1. I have reviewed this Amendment No. 1 to Annual Report on Form 10-K/A of Seattle Genetics, Inc.; and

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.

Date: November 26, 2010

/S/    TODD E. SIMPSON

Todd E. Simpson

Chief Financial Officer