Prosperity Bancshares (PB) 8-K Regulation FD Disclosure

Exhibit 99.1

Statements contained in this presentation which are not historical facts and which pertain to future operating results of Prosperity Bank and its subsidiaries constitute “forward-looking statements” within the meaning of the Private Securities Litigation reform Act of 1995. These forward-looking statements involve significant risks and uncertainties. Actual results may differ materially from the results discussed in these forward-looking statements. Factors that might cause such a difference include, but are not limited to, those discussed in the company’s periodic filings with the SEC. Copies of the SEC filings for Prosperity Bancshares^® may be downloaded from the Internet at no charge from www.prosperitybanktx.com.

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a Track Record of Success

• A Texas based Financial Holding Company with approximately $10 billion in assets

• 3^rd largest Texas based commercial bank by Texas deposits

• Strong balance sheet growth – 10 year CAGR of 30% loans, 28% deposits and 30% assets

• Strong earnings growth – 10 year CAGR of 14% for EPS (diluted) and 32% for net income

• Shareholder driven with approximately 9% inside ownership

• Excellent asset quality – Net Charge Offs / Average Loans of 0.01% for three months ending September 30, 2011

• Excellent cost control – under 50% efficiency ratio

• Since 2000, integrated over 20 successful acquisitions

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• Net Interest Margin was 4.02% for the third quarter 2011

• Non- Performing Assets to Average Earning Assets remain low at 0.16% or $13.363 million

• Strong Earnings of $36.373 million or $0.77 per share (diluted) and 1.52% Return on Assets for the third quarter 2011

• Tangible Common Equity Ratio improved to 6.89% at September 30, 2011

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U.S. Bureau of Labor Statistics

www.texaswideopenforbusiness.com

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U.S. Bureau of Labor Statistics

www.texaswideopenforbusiness.com

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U.S. Bureau of Labor Statistics

www.texaswideopenforbusiness.com

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$ in millions

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* Excluding the non-cash after tax impairment charge related to FNMA/FLHMC preferred stock of $6.5 million, EPS was $1.94

** Excluding the non-cash after tax impairment charge related to FNMA/FLHMC preferred stock of $9.1 million, EPS was $1.86

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September 30, 2011

3Q11 Cost of Deposits= 0.50%

	Amount		% of total
Non-interest Bearing DDA	$	1,861,907		23.87	%
Interest Bearing DDA		1,332,914		17.09
MMA & Savings		2,493,699		31.98
CD’s & IRA’s<100m		1,005,672		12.90
CD’s & IRA’s>100m		1,104,547		14.16
Total Deposits	$	7,798,739		100.00	%

$ in thousands

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$ in millions

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$ in thousands

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Texas Peer Group Includes: CFR, EBTX, FFIN, FBTX, IBOC, MCBI, SBSI, SNBI, SBIB, SBIT, TCBI, TRBS & TXUI

^ SNBI, SBIT, TRBS & TXUI have been acquired and were excluded from 2006 & 2007 and FBTX failed and was excluded from 2008

NOTE: 3Q11 does not include IBOC or TCBI as required data was not reported

Source: SNL Financial

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Texas Peer Group Includes: CFR, EBTX, FFIN, FBTX, IBOC, MCBI, SBSI, SNBI, SBIB, SBIT, TCBI, TRBS & TXUI

^ SNBI, SBIT, TRBS & TXUI have been acquired and were excluded from 2006 & 2007 and FBTX failed and was excluded from 2008

Source: SNL Financial

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Corporate Headquarters	Investor Contacts
Prosperity Bank Plaza	David Zalman
4295 San Felipe	Chairman & Chief Executive Officer
Houston, Texas 77027	979.543.2200
	david.zalman@prosperitybanktx.com
281.269.7199 Telephone	Dan Rollins
281.269-7222 Fax	President & Chief Operating Officer
www.prosperitybanktx.com	281.269.7199
	dan.rollins@prosperitybanktx.com
	David Hollaway
	Chief Financial Officer
	979.543.2200
	david.hollaway@prosperitybanktx.com

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As Originally Reported ($ in thousands, except EPS)	2005			2006			2007			2008			2009			2010			3Q 2011
Non Interest Income	$	30,021		$	33,982		$	52,923		$	52,370		$	60,097		$	53,833		$	14,581
Net Interest Income	$	110,897		$	138,145		$	200,435		$	227,729		$	307,101		$	318,148		$	82,538
Net Income	$	47,860		$	61,725		$	90,635	*	$	93,623	**	$	111,879		$	127,708		$	36,373
Book Value Per Share	$	16.69		$	20.26		$	25.51		$	27.24		$	29.03		$	31.11		$	32.87
Tangible Book Value Per Share	$	6.48		$	6.62		$	7.42		$	7.43		$	9.43		$	10.70		$	12.67
ROAA		1.42	%		1.44	%		1.49	%*		1.33	%**		1.26	%		1.38	%		1.52	%
ROAE		11.56	%		10.24	%		8.72	%*		7.85	%**		8.57	%		9.08	%		9.51	%
ROAE- tangible		29.88	%		31.53	%		32.34	%*		26.77	%**		28.66	%		27.40	%		25.03	%
Efficiency Ratio		48.91	%		45.27	%		46.19	%		46.51	%		46.27	%		44.83	%		42.38	%
Leverage Ratio		7.83	%		7.76	%		8.09	%		5.68	%		6.47	%		6.87	%		7.70	%
Tier I Risk Capital		15.34	%		13.52	%		13.13	%		10.27	%		12.61	%		13.64	%		15.47	%
Total Risk Capital		16.37	%		14.55	%		14.11	%		11.17	%		13.86	%		14.87	%		16.69	%
Tangible Ratio		5.46	%		5.24	%		5.88	%		4.19	%		5.53	%		5.86	%		6.89	%

* Does not include the non-cash after tax impairment charge related to FNMA/FLHMC preferred stock of $6.5 million.

** Does not include the non-cash after tax impairment charge related to FNMA/FLHMC preferred stock of $9.1 million.

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									At Announcement
	Date of Announcement	Seller	# of Branches	City	State	Type	Consideration	Accounting Method	PRSP Assets ($000)		Sellers’ Assets ($000)		Sellers’ Assets Contribution (%)		Deal Value ($ In MM
1	02/07/08	1st Choice Bancorp, Inc.	1	Houston	TX	Bank	Mixed	Purchase		6,372,343		313,900		4.69		66.2
2	05/01/07	The Bank of Navasota	1	Navasota	TX	Bank	Common Stock	Purchase		6,247,926		72,300		1.14		17.1
3	07/19/06	Texas United Bancshares, Inc.	34	La Grange	TX	Bank	Common Stock	Purchase		4,547,220		1,818,000		27.82		357.1
4	11/16/05	SNB Bancshares, Inc.	6	Houston	TX	Bank	Mixed	Purchase		3,493,972		1,121,747		24.30		242.7
5	09/12/05	Grapeland Bancshares, Inc.	2	Grapeland	TX	Bank	Common Stock	Purchase		3,479,747		73,000		2.15		7.3
6	10/26/04	FirstCapital Bankers, Inc.	20	Corpus Christi	TX	Thrift	Common Stock	Purchase		2,709,169		773,566		22.21		135.7
7	05/12/04	Village Bank and Trust	1	Austin	TX	Thrift	Cash	Purchase		2,449,553		110,400		4.31		20.2
8	04/26/04	Liberty Bank	4	Austin	TX	Thrift	Mixed	Purchase		2,449,553		186,000		7.06		42.0
9	10/06/03	First State Bank of North Texas	3	Dallas	TX	Bank	Mixed	Purchase		2,078,532		93,900		4.32		21.3
10	07/21/03	Mainbancorp	3	Dallas	TX	Bank	Mixed	Purchase		1,983,277		195,700		8.98		39.7
11	03/05/03	BankDallas SSB	1	Dallas	TX	Thrift	Cash	Purchase		1,822,256		40,716		2.19		7.0
12	02/03/03	Abrams Centre Bancshares, Inc.	1	Dallas	TX	Bank	Cash	Purchase		1,822,256		95,388		4.97		16.3
13	08/15/02	First National Bank of Bay City	1	Bay City	TX	Bank	Cash	Purchase		1,360,356		28,174		2.03		5.0
14	07/15/02	Southwest Bank Holding Company	2	Dallas	TX	Bank	Cash	Purchase		1,289,637		127,055		8.97		21.0
15	05/02/02	Paradigm Bancorporation, Incorporated	8	Houston	TX	Bank	Common Stock	Purchase		1,289,637		259,262		16.74		41.6
16	04/26/02	First State Bank	1	Needville	TX	Bank	Cash	Purchase		1,289,637		17,539		1.36		3.7
17	02/22/02	Texas Guaranty Bank, N.A.	2	Houston	TX	Bank	Cash	Purchase		1,262,152		75,019		5.61		11.8
18	11/08/00	Commercial Bancshares, Inc.	12	Houston	TX	Bank	Common Stock	Pooling		693,079		401,271		36.67		53.3
19	06/21/99	South Texas Bancshares, Inc.	3	Beeville	TX	Bank	Cash	Purchase		461,903		142,091		23.53		23.4
20	06/05/98	Union State Bank	1	East Bernard	TX	Bank	Cash	Purchase		339,287		79,174		18.92		17.6

Branch Acquisitions

	Date of Announcement	Seller	# of Branches	Branch Type	Branch Locale State	Amount of Deposits Transferred ($000)		Deposit Premium ($000)
1	2/8/2010	First Bank	19	Bank	TX		500,000		36,000
2	1/19/2010	U.S. Bank	3	Bank	TX		420,000		13,000
3	11/7/2008	Franklin Bank	46	Bank	TX		3,700,000		60,000
4	10/22/2007	Banco Popular North America	6	Bank	TX		140,000		NA
5	6/15/2000	Compass Bancshares, Inc.	5	Bank	TX		87,000		NA
6	2/27/1998	Grimes County Capital Corporation	1	Bank	TX		5,900		250
7	3/30/1997	Wells Fargo & Company	1	Bank	TX		NA		NA
8	3/11/1996	Victoria Bankshares, Inc.	1	Bank	TX		46,000		NA

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	12/31/2005				12/31/2006				12/31/2007				12/31/2008				12/31/2009				12/31/2010				CAGR
Loan Composition
Commercial	$	222.8	14.4	%	$	297.7	13.7	%	$	453.6	14.5	%	$	499.1	14.0	%	$	415.5	12.3	%	$	440.5	12.6	%		14.6	%
Construction	$	206.7	13.4	%	$	433.2	19.9	%	$	683.2	21.7	%	$	666.1	18.6	%	$	557.2	16.5	%	$	502.3	14.4	%		19.4	%
1-4 Family Residential	$	313.2	20.3	%	$	377.0	17.3	%	$	526.3	16.7	%	$	668.1	18.7	%	$	709.1	21.0	%	$	824.1	23.6	%		21.3	%
Home Equity	$	58.7	3.8	%	$	63.4	2.9	%	$	93.9	3.0	%	$	107.0	3.0	%	$	117.7	3.5	%	$	118.8	3.4	%		15.1	%
Commercial Real Estate	$	619.3	40.3	%	$	881.1	40.5	%	$	1,148.7	36.6	%	$	1,343.4	37.7	%	$	1,339.2	39.7	%	$	1,370.6	39.3	%		17.2	%
Agriculture	$	56.3	3.6	%	$	57.4	2.6	%	$	114.0	3.6	%	$	145.7	4.1	%	$	135.5	4.0	%	$	140.8	4.0	%		20.1	%
Consumer	$	65.1	4.2	%	$	66.7	3.1	%	$	123.2	3.9	%	$	137.7	3.9	%	$	102.4	3.0	%	$	88.0	2.5	%		6.2	%
Total Loans	$	1,542.1	100.0	%	$	2,176.5	100.0	%	$	3,142.9	100.0	%	$	3,567.1	100.0	%	$	3,376.7	100.0	%	$	3,485.0	100.0	%		17.7	%

$ in millions

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