| Cover - USD ($) | 12 Months Ended | ||
| Dec. 31, 2022 | Feb. 16, 2023 | Jun. 30, 2022 | |
| Cover [Abstract] | |||
| Document Type | 10-K/A | ||
| Amendment Flag | true | ||
| Amendment Description | This Amendment No. 1 on Form 10-K/A (“Amendment No. 1”) to the Annual Report on Form 10-K of PTC Therapeutics, Inc. (the “Company”) for the year ended December 31, 2022, originally filed with the Securities and Exchange Commission (the “SEC”) on February 21, 2023 (the “Original Filing”), is being filed solely for the purpose of amending Item 15, Exhibits and Financial Statement Schedules, of Part IV, to add reference to new Exhibits 10.57, 10.58 and 10.59. References in the exhibit index to these exhibits, which are incorporated by reference to prior filings by the Company with the SEC, were inadvertently omitted from the Original Filing due to an administrative error. | ||
| Document Annual Report | true | ||
| Document Transition Report | false | ||
| Document Period End Date | Dec. 31, 2022 | ||
| Document Fiscal Period Focus | FY | ||
| Document Fiscal Year Focus | 2022 | ||
| Current Fiscal Year End Date | --12-31 | ||
| Entity File Number | 001-35969 | ||
| Entity Registrant Name | PTC THERAPEUTICS, INC. | ||
| Entity Central Index Key | 0001070081 | ||
| Entity Tax Identification Number | 04-3416587 | ||
| Entity Incorporation, State or Country Code | DE | ||
| Entity Address, Address Line One | 100 Corporate Court | ||
| Entity Address, City or Town | South Plainfield | ||
| Entity Address, State or Province | NJ | ||
| Entity Address, Postal Zip Code | 07080 | ||
| City Area Code | 908 | ||
| Local Phone Number | 222-7000 | ||
| Title of 12(b) Security | Common Stock, $0.001 par value per share | ||
| Trading Symbol | PTCT | ||
| Security Exchange Name | NASDAQ | ||
| Entity Well-known Seasoned Issuer | Yes | ||
| Entity Voluntary Filers | No | ||
| Entity Current Reporting Status | Yes | ||
| Entity Interactive Data Current | Yes | ||
| Entity Filer Category | Large Accelerated Filer | ||
| Entity Small Business | false | ||
| Entity Emerging Growth Company | false | ||
| Entity Shell Company | false | ||
| Entity Public Float | $ 2,129,532,394 | ||
| Entity Common Stock, Shares Outstanding | 73,815,144 | ||
| Documents Incorporated by Reference [Text Block] | DOCUMENTS INCORPORATED BY REFERENCE Part III of this Annual Report incorporates by reference information from the definitive Proxy Statement for the registrant’s 2023 Annual Meeting of Shareholders which is expected to be filed with the Securities and Exchange Commission not later than 120 days after the registrant’s fiscal year ended December 31, 2022. | ||
| ICFR Auditor Attestation Flag | true | ||
| Auditor Name | Ernst & Young LLP | ||
| Auditor Firm ID | 42 | ||
| Auditor Location | Location Iselin, New Jersey |
