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Exhibit 21.1
LIST OF SUBSIDIARIES
Name |
| Jurisdiction |
| Ownership |
Advanced Medicine East, Inc |
| Delaware |
| 100% |
Innoviva Strategic Partners LLC |
| Delaware |
| 100% |
Innoviva Royalty Sub LLC |
| Delaware |
| 100% |
Innoviva TRC Holdings LLC |
| Delaware |
| 100% |
Innoviva Strategic Opportunities LLC |
| Delaware |
| 100% |
ISP Fund LLP |
| Delaware |
| 100% |
Innoviva Specialty Therapeutics Holdings LLC |
| Delaware |
| 100% |
Innoviva Specialty Therapeutics Inc. |
| Delaware |
| 100% |
Entasis Therapeutics Holdings Inc. |
| Delaware |
| 100% |
Entasis Therapeutics Inc. |
| Delaware |
| 100% |
Entasis Therapeutics Limited |
| United Kingdom |
| 100% |
Entasis Therapeutics Security Corporation |
| Massachusetts |
| 100% |
Entasis Therapeutics (Ireland) Limited |
| Ireland |
| 100% |
La Jolla Pharmaceutical Company |
| Delaware |
| 100% |
La Jolla Pharma, LLC |
| Delaware |
| 100% |
Tetraphase Pharmaceuticals, Inc. |
| Delaware |
| 100% |
La Jolla Pharmaceutical Holdings, LLC |
| Delaware |
| 100% |
La Jolla Pharmaceutical I B.V. |
| Netherlands |
| 100% |
La Jolla Pharmaceutical II B.V. |
| Netherlands |
| 100% |
La Jolla Pharmaceutical III B.V. |
| Netherlands |
| 100% |