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Exhibit 21
SUBSIDIARIES OF THE REGISTRANT
Lung Bioengineering Inc., a Delaware corporation
Lung Biotechnology PBC, a Delaware public benefit corporation
Revivicor, Inc., a Delaware corporation
SteadyMed Ltd., an Israeli company
SteadyMed Therapeutics, Inc., a Delaware corporation
United Therapeutics Europe, Ltd., a company incorporated under the laws of England and Wales
Unither Biotech Inc., a Canadian company
Unither Bioelectronics, Inc., a Canadian company
Unither Pharma, LLC, a Delaware limited liability company
Unither Pharmaceuticals, LLC, a Delaware limited liability company
Unither Telmed, Ltd., a Delaware corporation
Unither Therapeutik GmbH, a German company
Unither.com, Inc., a Delaware corporation
UTASIA Inc., a Delaware corporation
1109 Spring Managing Holdings, LLC, a Delaware limited liability company
1109 Spring Managing Member, LLC, a Delaware limited liability company
1111 Spring Holdings, LLC, a Delaware limited liability company