Manulife Financial (MFC) 424B3 Prospectus supplement

Registration Nos. 333-168694 and 333-168694-1
Filed Pursuant to Rule 424(b)(3)

JOHN HANCOCK LIFE INSURANCE COMPANY (U.S.A.)

Supplement dated September 26, 2011 to PROSPECTUSES dated August 8, 2011

This Supplement applies to INFLATION GUARD ANNUITY Contracts issued by John Hancock Life Insurance Company (U.S.A.). It supplements prospectuses dated August 8, 2011, for these Contracts.

You should read this Supplement together with the current prospectus for the Contract you purchased (the “Annuity Prospectus”), and retain all documents for future reference. We define certain terms in this Supplement. If a term is not defined in this Supplement, it has the meaning given to it in the Annuity Prospectus. If you would like another copy of the Annuity Prospectus, please contact our Annuities Service Center at 800-824-0335 to request a free copy. You may also visit our website atwww.jhannuities.com.

Changes to Historical Rates for CPI and S&P

We replace the table that appears in “Appendix D: Historical rates for CPI and S&P” with the following:

Appendix D: Historical rates for CPI and S&P

Year over Year change in CPI-U and S&P 500 Indices since 1950

Using January values of each year

			CPI Index					S&P 500 Index
			Year over					Year over
	CPI		Year			S&P 500		Year
Month	Index		% Change			Index		% Change
1/31/1950		23.50		--			17.05		--
1/31/1951		25.40		8.09	%		21.66		27.04	%
1/31/1952		26.50		4.33	%		24.14		11.45	%
1/31/1953		26.60		0.38	%		26.38		9.28	%
1/31/1954		26.90		1.13	%		26.08		-1.14	%
1/31/1955		26.70		-0.74	%		36.63		40.45	%
1/31/1956		26.80		0.37	%		43.82		19.63	%
1/31/1957		27.60		2.99	%		44.72		2.05	%
1/31/1958		28.60		3.62	%		41.70		-6.75	%
1/31/1959		29.00		1.40	%		55.42		32.90	%
1/31/1960		29.30		1.03	%		55.61		0.34	%
1/31/1961		29.80		1.71	%		61.78		11.10	%
1/31/1962		30.00		0.67	%		68.84		11.43	%
1/31/1963		30.40		1.33	%		66.20		-3.83	%
1/31/1964		30.90		1.64	%		77.04		16.37	%
1/31/1965		31.20		0.97	%		87.56		13.66	%
1/31/1966		31.80		1.92	%		92.88		6.08	%
1/31/1967		32.90		3.46	%		86.61		-6.75	%
1/31/1968		34.10		3.65	%		92.24		6.50	%
1/31/1969		35.60		4.40	%		103.01		11.68	%
1/31/1970		37.80		6.18	%		85.02		-17.46	%
1/31/1971		39.80		5.29	%		95.88		12.77	%
1/31/1972		41.10		3.27	%		103.94		8.41	%
1/31/1973		42.60		3.65	%		116.03		11.63	%
1/31/1974		46.60		9.39	%		96.57		-16.77	%
1/31/1975		52.10		11.80	%		76.98		-20.29	%
1/31/1976		55.60		6.72	%		100.86		31.02	%
1/31/1977		58.50		5.22	%		102.03		1.16	%
1/31/1978		62.50		6.84	%		89.25		-12.53	%
1/31/1979		68.30		9.28	%		99.93		11.97	%
1/31/1980		77.80		13.91	%		114.16		14.24	%

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Appendix D: Historical rates for CPI and S&P

Year over Year change in CPI-U and S&P 500 Indices since 1950

Using January values of each year

			CPI Index					S&P 500 Index
			Year over					Year over
	CPI		Year			S&P 500		Year
Month	Index		% Change			Index		% Change
1/31/1981		87.00		11.83	%		129.55		13.48	%
1/31/1982		94.30		8.39	%		120.40		-7.06	%
1/31/1983		97.80		3.71	%		145.30		20.68	%
1/31/1984		101.90		4.19	%		163.41		12.46	%
1/31/1985		105.50		3.53	%		179.63		9.93	%
1/31/1986		109.60		3.89	%		211.78		17.90	%
1/31/1987		111.20		1.46	%		274.08		29.42	%
1/31/1988		115.70		4.05	%		257.07		-6.21	%
1/31/1989		121.10		4.67	%		297.47		15.72	%
1/31/1990		127.40		5.20	%		329.08		10.63	%
1/31/1991		134.60		5.65	%		343.93		4.51	%
1/31/1992		138.10		2.60	%		408.79		18.86	%
1/31/1993		142.60		3.26	%		438.78		7.34	%
1/31/1994		146.20		2.52	%		481.61		9.76	%
1/31/1995		150.30		2.80	%		470.42		-2.32	%
1/31/1996		154.40		2.73	%		636.02		35.20	%
1/31/1997		159.10		3.04	%		786.16		23.61	%
1/31/1998		161.60		1.57	%		980.28		24.69	%
1/31/1999		164.30		1.67	%		1279.64		30.54	%
1/31/2000		168.80		2.74	%		1394.46		8.97	%
1/31/2001		175.10		3.73	%		1366.01		-2.04	%
1/31/2002		177.10		1.14	%		1130.20		-17.26	%
1/31/2003		181.70		2.60	%		855.70		-24.29	%
1/31/2004		185.20		1.93	%		1131.13		32.19	%
1/31/2005		190.70		2.97	%		1181.27		4.43	%
1/31/2006		198.30		3.99	%		1280.08		8.36	%
1/31/2007		202.42		2.08	%		1438.24		12.36	%
1/31/2008		211.08		4.28	%		1378.55		-4.15	%
1/31/2009		211.14		0.03	%		825.88		-40.09	%
1/31/2010		216.69		2.63	%		1073.87		30.03	%
1/31/2011		220.22		1.63	%		1286.12		19.76	%

Sources: The US Consumer Price Index — All Urban Consumers (CPI-U) — is compiled monthly by the U.S. Bureau of Labor Statistics.
  The S&P 500 Index is a trademark of Standard & Poor’s™.

You should retain this Supplement for future reference.

Supplement dated September 26, 2011

09/11: 333-168694
333-168694-1

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