Exhibit 99.1
JOINT FILERS’ SIGNATURES
ESSETIFIN S.P.A.
Name: Marino Zigrossi
Title: Managing Director
Date: November 30, 2017
LEADIANT BIOSCIENCES, INC.
Name: Marino Zigrossi
Title: Attorney-in-fact
Date: November 30, 2017
Enrico Cavazza
Name: Marino Zigrossi
Title: Attorney-in-fact**
Date: November 30, 2017
Francesca Cavazza
Name: Marino Zigrossi
Title: Attorney-in-fact**
Date: November 30, 2017
Silvia Cavazza
Name: Marino Zigrossi
Title: Attorney-in-fact**
Date: November 30, 2017
Martina Cavazza Preta
Name: Marino Zigrossi
Title: Attorney-in-fact**
Date: November 30, 2017
Paolo Cavazza
Name: Fabio Poma
Title: Attorney-in-fact
Date: November 30, 2017
** Power of attorney was previously filed with Securities and Exchange Commission as an exhibit to the Form 3/A filed on October 4, 2017, with respect to the common stock of Fennec Pharmaceuticals, Inc.