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CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the use in this Registration Statement on Form S-1 of our report dated April 15, 2008 relating to the financial statements and financial statement schedule of Epocrates, Inc., which appears in such Registration Statement. We also consent to the references to us under the heading "Experts" in such Registration Statement.
/s/ PRICEWATERHOUSECOOPERS LLP
San Jose, California
October 27, 2008
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM