| Document and Entity Information | Mar. 25, 2024 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | Mar. 25, 2024 |
| Entity File Number | 001-36138 |
| Entity Registrant Name | Ayala Pharmaceuticals, Inc. |
| Entity Central Index Key | 0001100397 |
| Entity Incorporation, State or Country Code | DE |
| Entity Tax Identification Number | 84-1521955 |
| Entity Address, Address Line One | 9 DEER PARK DRIVE |
| Entity Address, Address Line Two | SUITE K-1 |
| Entity Address, City or Town | MONMOUTH JUNCTION |
| Entity Address, State or Province | NJ |
| Entity Address, Postal Zip Code | 08852 |
| City Area Code | 732 |
| Local Phone Number | 545-1590 |
| Entity Emerging Growth Company | false |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
