Exhibit 31.1
CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER
I, Laurence J.N. Cooper, certify that:
| 1. | I have reviewed this Amendment No. 1 to Annual Report on Form10-K/A of ZIOPHARM Oncology, Inc.; and | |
| 2. | Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report. | |
Date: April 30, 2018
/s/ Laurence J.N. Cooper |
Laurence J.N. Cooper, M.D., Ph.D. Chief Executive Officer |
| (Principal Executive Officer) |
