Globalscape (GSB) 8-K Changes in Registrant's Certifying Accountant

Exhibit 16.1

October 19, 2016

Securities and Exchange Commission

Washington, D.C. 20549

Commissioners:

We have read GlobalSCAPE, Inc.'s statements included under Item 4.01 of its Form 8‐K filed on October 19, 2016, and we agree with such statements concerning our firm.

/s/ Padgett, Stratemann & Co., L.L.P.,

a member of the RSM Alliance

San Antonio, Texas