[TARGACEPT, INC. LETTERHEAD]
April 16, 2010
VIA EDGAR
Filing Desk
Securities and Exchange Commission
100 F Street, N.E.
Washington, D.C. 20549
| Re: | Targacept, Inc. Notice of Annual Meeting and Internet Availability of Proxy Materials |
Ladies and Gentlemen:
On behalf of Targacept, Inc. (the “Company”), accompanying this letter for filing please find: (i) the notice of annual meeting and internet availability of proxy materials to be provided by the Company to its stockholders pursuant to Rule 14a-16 under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), in connection with the Company’s 2010 Annual Meeting of Stockholders scheduled for June 10, 2010; and (ii) the Schedule 14A cover page required pursuant to Rule 14a-6(m) promulgated under the Exchange Act.
| Sincerely, | ||
| Targacept, Inc. | ||
| By: | /s/ Peter A. Zorn | |
| Peter A. Zorn | ||
| Senior Vice President, Legal Affairs, General | ||
| Counsel and Secretary | ||
