Cryoport (CYRX) 10-K 8 Mar 18 2017 FY Annual report Financial data

Document And Entity Information

Document And Entity Information - USD ($)	12 Months Ended
	Dec. 31, 2017	Mar. 01, 2018	Jun. 30, 2017
Document Information [Line Items]
Document Type	10-K
Amendment Flag	false
Document Period End Date	Dec. 31, 2017
Document Fiscal Year Focus	2,017
Document Fiscal Period Focus	FY
Entity Registrant Name	Cryoport, Inc.
Entity Central Index Key	1,124,524
Current Fiscal Year End Date	--12-31
Entity Well-known Seasoned Issuer	No
Entity Voluntary Filers	No
Entity Current Reporting Status	Yes
Entity Filer Category	Smaller Reporting Company
Entity Public Float			$ 116,610,411
Trading Symbol	CYRX
Entity Common Stock, Shares Outstanding		27,339,977

Consolidated Balance Sheets

Consolidated Balance Sheets - USD ($)	Dec. 31, 2017	Dec. 31, 2016
Current Assets:
Cash and cash equivalents	$ 15,042,189	$ 4,524,529
Accounts receivable, net of allowance for doubtful accounts of $70,000 and $75,000, respectively	1,625,476	1,195,479
Inventories	114,796	89,499
Prepaid expenses and other current assets	516,427	286,919
Total current assets	17,298,888	6,096,426
Property and equipment, net	2,511,174	1,647,104
Intangible assets, net	90,646	5,000
Deposits	363,403	363,403
Total assets	20,264,111	8,111,933
Current Liabilities:
Accounts payable and other accrued expenses	1,259,629	1,160,299
Accrued compensation and related expenses	925,514	419,034
Related-party notes payable and accrued interest, net of discount of $0 and $6,100, respectively	0	651,934
Total current liabilities	2,185,143	2,231,267
Deferred rent liability	192,202	200,264
Total liabilities	2,377,345	2,431,531
Commitments and contingencies
Stockholders’ Equity:
Common stock, $0.001 par value; 50,000,000 shares authorized; 25,701,924 and 17,604,283 issued and outstanding at December 31, 2017 and 2016, respectively	25,702	17,604
Additional paid-in capital	149,293,947	129,196,680
Accumulated deficit	(131,432,883)	(123,533,882)
Total stockholders’ equity	17,886,766	5,680,402
Total liabilities and stockholders’ equity	20,264,111	8,111,933
Class A convertible preferred stock [Member]
Stockholders’ Equity:
Preferred stock value	0	0
Class B Convertible Preferred Stock [Member]
Stockholders’ Equity:
Preferred stock value	$ 0	$ 0

Consolidated Balance Sheets (Pa

Consolidated Balance Sheets (Parenthetical) - USD ($)	Dec. 31, 2017	Dec. 31, 2016
Allowance for doubtful accounts receivable	$ 70,000	$ 75,000
Preferred stock, par value (in dollars per share)	$ 0.001	$ 0.001
Preferred stock, shares authorized	2,500,000	2,500,000
Common stock, par value (in dollars per share)	$ 0.001	$ 0.001
Common stock, shares authorized	50,000,000	50,000,000
Common stock, shares issued	25,701,924	17,604,283
Common stock, shares outstanding	25,701,924	17,604,283
Related Party Notes payable, Other Payable [Member]
Debt Instrument, Unamortized Discount	$ 0	$ 6,100
Class A Convertible Preferred Stock [Member]
Preferred stock, par value (in dollars per share)	$ 0.001	$ 0.001
Preferred stock, shares authorized	800,000	800,000
Preferred stock, shares issued	0	0
Preferred stock, shares outstanding	0	0
Class B Convertible Preferres Stock [Member]
Preferred stock, par value (in dollars per share)	$ 0.001	$ 0.001
Preferred stock, shares authorized	585,000	585,000
Preferred stock, shares issued	0	0
Preferred stock, shares outstanding	0	0

Consolidated Statements of Oper

Consolidated Statements of Operations - USD ($)	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017	Dec. 31, 2016
Revenues	$ 6,123,271	$ 11,954,267	$ 7,678,816
Cost of revenues	3,603,655	5,987,834	4,577,393
Gross margin	2,519,616	5,966,433	3,101,423
Operating costs and expenses:
General and administrative	4,634,775	7,420,837	6,449,196
Sales and marketing	3,573,204	5,232,406	4,820,230
Engineering and development	453,628	1,205,692	598,106
Total operating costs and expenses	8,661,607	13,858,935	11,867,532
Loss from operations	(6,141,991)	(7,892,502)	(8,766,109)
Other expense:
Interest expense	(58,222)	(15,693)	(139,416)
Warrant inducement and repricing expense	(4,195,252)	0	(4,195,252)
Other income (expense), net	(1,898)	14,337	(6,770)
Total other expense, net	(4,255,372)	(1,356)	(4,341,438)
Loss before provision for income taxes	(10,397,363)	(7,893,858)	(13,107,547)
Provision for income taxes	(5,673)	(5,143)	(5,673)
Net loss	(10,403,036)	(7,899,001)	(13,113,220)
Undeclared cumulative preferred dividends	0	0	(75,460)
Net loss attributable to common stockholders	$ (10,403,036)	$ (7,899,001)	$ (13,188,680)
Net loss per share attributable to common stockholders - basic and diluted	$ (0.68)	$ (0.34)	$ (0.93)
Weighted average common shares outstanding - basic and diluted	15,393,402	22,963,382	14,220,977

Consolidated Statements of Stoc

Consolidated Statements of Stockholders' Equity (Deficit) - USD ($)	Total	Class A Preferred Stock	Class B Preferred Stock	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit
Balance at Mar. 31, 2016	$ 3,095,927	$ 0	$ 0	$ 12,251	$ 116,214,522	$ (113,130,846)
Balance (in shares) at Mar. 31, 2016		0	0	12,251,313
Net loss	(10,403,036)	$ 0	$ 0	$ 0	0	(10,403,036)
Stock-based compensation expense	2,281,233	0	0	0	2,281,233	0
Issuance of common stock for April tender offer, net of costs of $281,500	2,244,247	$ 0	$ 0	$ 2,021	2,242,226	0
Issuance of common stock for April tender offer, net of costs of $281,500 (in shares)		0	0	2,020,597
Issuance of common stock for October tender offer, net of costs of $477,300	3,229,111	$ 0	$ 0	$ 2,471	3,226,640	0
Issuance of common stock for October tender offer, net of costs of $477,300 (in shares)		0	0	2,470,913
Supplemental warrant expense in connection with the October tender offer	615,899	$ 0	$ 0	$ 0	615,899	0
Warrant repricing expense	3,579,352	0	0	0	3,579,352	0
Issuance of common stock for Rights Offering, net of costs of $315,000	989,898	$ 0	$ 0	$ 842	989,056	0
Issuance of common stock for Rights Offering, net of costs of $315,000 (in shares)		0	0	841,873
Issuance of common stock for board of director compensation	47,771	$ 0	$ 0	$ 19	47,752	0
Issuance of common stock for board of director compensation (in shares)		0	0	19,587
Balance at Dec. 31, 2016	5,680,402	$ 0	$ 0	$ 17,604	129,196,680	(123,533,882)
Balance (in shares) at Dec. 31, 2016		0	0	17,604,283
Net loss	(7,899,001)	$ 0	$ 0	$ 0	0	(7,899,001)
Stock-based compensation expense	3,477,781	0	0	0	3,477,781	0
Issuance of common stock for board of director compensation	70,000	$ 0	$ 0	$ 16	69,984	0
Issuance of common stock for board of director compensation (in shares)		0	0	15,872
Proceeds from common stock offering, net of costs of $170,326	11,405,924	$ 0	$ 0	$ 6,325	11,399,599	0
Proceeds from common stock offering, net of costs of $170,326 (in shares)		0	0	6,325,000
Proceeds from exercise of stock options and warrants	5,151,660	$ 0	$ 0	$ 1,757	5,149,903	0
Proceeds from exercise of stock options and warrants (in shares)		0	0	1,756,769
Balance at Dec. 31, 2017	$ 17,886,766	$ 0	$ 0	$ 25,702	$ 149,293,947	$ (131,432,883)
Balance (in shares) at Dec. 31, 2017		0	0	25,701,924

Consolidated Statements of Sto6

Consolidated Statements of Stockholders' Equity (Deficit) (Parenthetical) - USD ($)	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs		$ 170,326
Rights Offering [Member]
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs	$ 315,000
April Tender Offer [Member]
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs	281,500
October Tender Offer [Member]
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs	$ 477,300

Consolidated Statements of Cash

Consolidated Statements of Cash Flows - USD ($)	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017	Dec. 31, 2016
Cash Flows From Operating Activities:
Net loss	$ (10,403,036)	$ (7,899,001)	$ (13,113,220)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	301,297	664,831	374,202
Amortization of debt discount and deferred financing costs	18,729	6,130	84,784
Stock-based compensation expense to employees, directors and consultants	2,329,003	3,547,781	3,117,946
Warrant inducement and repricing expense	4,195,252	0	4,195,252
Loss on disposal of property and equipment	37,588	186,030	169,053
Provision for bad debt	42,646	11,646	2,503
Changes in operating assets and liabilities:
Accounts receivable	(217,126)	(441,643)	(581,197)
Inventories	(19,698)	(25,297)	(74,895)
Prepaid expenses and other current assets	(38,190)	(261,489)	2,046
Accounts payable and other accrued expenses	88,637	123,249	51,320
Accrued compensation and related expenses	(89,720)	506,480	41,921
Accrued interest	11,410	(1,843)	11,409
Net cash used in operating activities	(3,743,208)	(3,583,126)	(5,718,876)
Cash Flows From Investing Activities:
Purchases of property and equipment	(657,667)	(1,714,931)	(1,062,926)
Patent costs	(5,000)	(85,646)	(5,000)
Net cash used in investing activities	(662,667)	(1,800,577)	(1,067,926)
Cash Flows From Financing Activities:
Proceeds from exercise of stock options and warrants	0	5,151,660	0
Proceeds from the rights offering, net of offering costs	989,898	0	989,898
Proceeds from public offering, net of offering costs	0	11,405,924	0
Repayment of notes payable	0	0	0
Repayment of related-party notes payable	(325,378)	(656,221)	(399,350)
Net cash provided by financing activities	6,137,878	15,901,363	6,063,906
Net change in cash and cash equivalents	1,732,003	10,517,660	(722,896)
Cash and cash equivalents - beginning of period	2,792,526	4,524,529	5,247,425
Cash and cash equivalents - end of period	4,524,529	15,042,189	4,524,529
Supplemental Disclosure of Cash Flow Information:
Cash paid for interest	43,223	4,744	9,534
Cash paid for income taxes	5,673	5,143	5,673
Supplemental Disclosure of Non-Cash Investing and Financing Activities:
Cumulative undeclared preferred dividends recorded upon conversion of Class A convertible preferred stock and Class B convertible preferred stock into common stock	0	0	1,068,055
Estimated relative fair value of warrants issued in connection with related-party notes payable	0	0	26,901
Leasehold improvements paid by tenant allowance included in accounts payable and accrued expenses	0	0	200,000
Reclassification of shipper inventory to property and equipment	0	0	38,276
Deferred offering costs in connection with future warrant repricing included in accounts payable and prepaid expenses and other current assets	0	31,981	0
April Tender Offer [Member]
Cash Flows From Financing Activities:
Proceeds from the offer, net of offering costs	2,244,247	0	2,244,247
October Tender Offer [Member]
Cash Flows From Financing Activities:
Proceeds from the offer, net of offering costs	$ 3,229,111	$ 0	$ 3,229,111

Nature of the Business

Nature of the Business	12 Months Ended
	Dec. 31, 2017
Nature of the Business [Abstract]
Nature of the Business	Note 1. Nature of the Business Cryoport, Inc. (“Cryoport”) is the premier provider of cryogenic logistics solutions to the life sciences industry through its purpose-built proprietary packaging, information technology and specialized cold chain logistics expertise. The Company provides leading edge logistics solutions for biologic materials, such as immunotherapies, stem cells, CAR-T cells and reproductive cells for clients worldwide. Leading global companies, such as FedEx, UPS and DHL have each separately selected Cryoport as the preferred cryogenic logistics provider for time- and temperature-sensitive biological material. Cryoport actively supports points-of-care, contract research organizations, central laboratories, pharmaceutical companies, contract manufacturers and university researchers. The Company is a Nevada corporation and its common stock is traded on the NASDAQ Capital Market exchange under the ticker symbol “CYRX.”

Summary of Significant Accounti

Summary of Significant Accounting Policies	12 Months Ended
	Dec. 31, 2017
Summary of Significant Accounting Policies [Abstract]
Summary of Significant Accounting Policies	Note 2. Summary of Significant Accounting Policies The accompanying consolidated financial statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”). In September 2016, the Company elected to change its fiscal year end from March 31 to a new fiscal year end of December 31. Accordingly, the accompanying consolidated financial statements include audited financial statements for the year ended December 31, 2017 and the nine-month transition period ended December 31, 2016 and unaudited financial statements for the year ended December 31, 2016. As a result of the change, the Company’s quarterly reporting periods are comprised of the three calendar months ending March 31, June 30 and September 30. The accompanying consolidated financial statements include the accounts of Cryoport, Inc. and its wholly owned subsidiaries, Cryoport Systems, Inc. and Cryoport Europe Limited (collectively, the “Company”). All intercompany accounts and transactions have been eliminated. The preparation of the consolidated financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the consolidated financial statements and the reported amounts of revenues and expenses during the reporting periods. Actual results could differ from estimated amounts. The Company’s significant estimates include the allowance for doubtful accounts, recoverability of long-lived assets, allowance for inventory obsolescence, deferred taxes and their accompanying valuations, and valuation of equity instruments. The Company’s financial instruments consist of cash and cash equivalents, accounts receivable, related-party notes payable, accounts payable and accrued expenses. The carrying value for all such instruments, except for related-party notes payable, approximates fair value at December 31, 2017 and 2016 due to their short-term nature. The difference between the fair value and recorded values of the related-party notes payable is not significant. The Company considers highly liquid investments with original maturities of 90 The Company maintains its cash accounts in financial institutions. Accounts at these institutions are insured by the Federal Deposit Insurance Corporation (“FDIC”) with basic deposit insurance coverage limits up to $ 250,000 14.8 The Company grants credit to customers within the U.S. and to a limited number of international customers and does not require collateral. Revenues from international customers are generally secured by advance payments except for a limited number of established foreign customers. The Company generally requires advance or credit card payments for initial revenues from new customers. The Company’s ability to collect receivables is affected by economic fluctuations in the geographic areas and industries served by the Company. Reserves for uncollectible amounts are provided based on past experience and a specific analysis of the accounts, which management believes is sufficient. Accounts receivable at December 31, 2017 and 2016 are net of reserves for doubtful accounts of $ 70,000 75,000 The majority of the Company’s customers are in the biotechnology, pharmaceutical and life science industries. Consequently, there is a concentration of accounts receivable within these industries, which is subject to normal credit risk. No single customer owed the Company more than 10 The Company has revenue from foreign customers primarily in Europe, Japan, Canada, India and Australia. During the year ended December 31, 2017 and the nine-month transition period ended December 31, 2016, the Company had revenues from foreign customers of approximately $ 1.3 750,400 11.0 12.3 10 The Company’s inventories consist of packaging materials and accessories that are sold to customers. Inventories are stated at the lower of cost and net realizable value. Cost is determined using the standard cost method which approximates the first-in, first-to-expire method. Inventories are reviewed periodically for slow-moving or obsolete status. The Company writes down the carrying value of its inventories to reflect situations in which the cost of inventories is not expected to be recovered. Once established, write-downs of inventories are considered permanent adjustments to the cost basis of the obsolete or excess inventories. Raw materials and finished goods include material costs less reserves for obsolete or excess inventories. The Company evaluates the current level of inventories considering historical trends and other factors, such as selling prices and costs of completion, disposal and transportation, and based on the evaluation, records adjustments to reflect inventories at net realizable value. These adjustments are estimates, which could vary significantly from actual results if future economic conditions, customer demand, competition or other relevant factors differ from expectations. These estimates require us to make assessments about future demand for the Company’s products in order to categorize the status of such inventories items as slow-moving, obsolete or in excess-of-need. These estimates are subject to the ongoing accuracy of the Company’s forecasts of market conditions, industry trends, competition and other factors. The Company provides shipping containers to its customers and charges a fee in exchange for the use of the container. The Company’s arrangements are similar to the accounting standard for leases since they convey the right to use the container over a period of time. The Company retains the title to the containers and provides its customers the use of the container for a specific shipping cycle. At the culmination of the customer’s shipping cycle, the container is returned to the Company. As a result, the Company classifies the containers as property and equipment for the per-use container program. Property and equipment are recorded at cost. Cryogenic shippers and data loggers, which comprise 47 44 Betterments, renewals and extraordinary repairs that extend the lives of the assets are capitalized; other repairs and maintenance charges are expensed as incurred. The cost and related accumulated depreciation and amortization applicable to assets retired are removed from the accounts, and the gain or loss on disposition is recognized in the consolidated statements of operations. Intangible assets are comprised of patents and trademarks and software development costs. The Company capitalizes costs of obtaining patents and trademarks, which are amortized, using the straight-line method over their estimated useful life of five years once the patent or trademark has been issued. The Company capitalizes certain costs related to software developed for internal use. Software development costs incurred during the preliminary or maintenance project stages are expensed as incurred, while costs incurred during the application development stage are capitalized and amortized using the straight-line method over the estimated useful life of the software, which is five years. Capitalized costs include purchased materials and costs of services. If indicators of impairment exist, we assess the recoverability of the affected long-lived assets by determining whether the carrying value of such assets can be recovered through undiscounted future operating cash flows. If impairment is indicated, we measure the amount of such impairment by comparing the fair value to the carrying value. We believe the future cash flows to be received from the long-lived assets will exceed the assets’ carrying value, and accordingly, we have not recognized any impairment losses through December 31, 2017. Deferred Financing Costs Deferred financing costs represent costs incurred in connection with the issuance of the debt instruments and equity financings. Deferred financing costs related to the issuance of debt are amortized over the term of the financing instrument using the effective interest method while offering costs from equity financings are netted against the gross proceeds received from the equity financings. The Company accounts for income taxes under the provision of the Financial Accounting Standards Board (“FASB”) Accounting Standards Codification (“ASC”) 740, Income Taxes Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment date. A valuation allowance is provided for certain deferred tax assets if it is more likely than not that the Company will not realize tax assets through future operations. Based on the weight of available evidence, the Company’s management has determined that it is more likely than not that the net deferred tax assets will not be realized. Therefore, the Company has recorded a full valuation allowance against the net deferred tax assets. The Company’s provision for income taxes consists of state minimum taxes. The Company’s policy is to recognize interest and/or penalties related to income tax matters in income tax expense. The Company had no accrual for interest or penalties on its consolidated balance sheets at December 31, 2017 and 2016 and has not recognized interest and/or penalties in the consolidated statements of operations for the year ended December 31, 2017 and the nine months ended December 31, 2016. The Company is subject to taxation in the U.S. and various state jurisdictions. As of December 31, 2017, the Company is no longer subject to U.S. federal examinations for years before 2014 and for California franchise and income tax examinations for years before 2013. However, to the extent allowed by law, the taxing authorities may have the right to examine prior periods where net operating losses were generated and carried forward, and make adjustments up to the amount of the net operating loss carry forward amount. The Company is not currently under examination by U.S. federal or state jurisdictions. The Company provides shipping containers to its customers and charges a fee in exchange for the use of the containers. The Company’s arrangements are similar to the accounting standard for leases since they convey the right to use the containers over a period of time. The Company retains title to the containers and provides its customers the use of the containers for a specified shipping cycle. At the culmination of the customer’s shipping cycle, the container is returned to the Company. The Company recognizes revenue for the use of the shipper at the time of the delivery of the shipper to the end user of the enclosed materials, and at the time that collectability is reasonably certain. Revenue is based on gross amounts, net of discounts and allowances. The Company also provides logistics support and management services to some customers, which may include onsite logistics personnel. Revenue is recognized for these services as services are rendered and at the time that collectability is reasonably certain. The Company classifies amounts billed for shipping and handling as revenue. Shipping and handling fees and costs are included in cost of revenues in the accompanying consolidated statements of operations. Expenditures relating to engineering and development are expensed in the period incurred. The Company accounts for stock-based payments to employees and directors in accordance with stock-based payment accounting guidance which requires all stock-based payments to employees and directors, including grants of employee stock options and warrants, to be recognized based upon their estimated fair values. The fair value of stock-based awards is estimated at grant date using the Black-Scholes Option Pricing Method (“Black-Scholes”) and the portion that is ultimately expected to vest is recognized as compensation cost over the requisite service period. The Company accounts for forfeitures of unvested awards as they occur. The Company uses Black-Scholes to estimate the fair value of stock-based awards. The determination of fair value using Black-Scholes is affected by the Company’s stock price as well as assumptions regarding a number of complex and subjective variables, including expected stock price volatility, risk-free interest rate, expected dividends and projected employee stock option exercise behaviors. The Company’s stock-based compensation plans are discussed further in Note 10. Issuances of the Company’s common stock for acquiring goods or services are measured at the estimated fair value of the consideration received or the estimated fair value of the equity instruments issued, whichever is more reliably measurable. The measurement date for the estimated fair value of the equity instruments issued to consultants or vendors is determined at the earlier of (i) the date at which a commitment for performance to earn the equity instruments is reached (a “performance commitment” which would include a penalty considered to be of a magnitude that is a sufficiently large disincentive for nonperformance) or (ii) the date at which performance is complete. When it is appropriate for the Company to recognize the cost of a transaction during financial reporting periods prior to the measurement date, for purposes of recognition of costs during those periods, the equity instrument is measured at the then-current estimated fair values at each of those interim financial reporting dates. We calculate basic and diluted net income (loss) per share attributable to common stockholders using the weighted average number of common shares outstanding during the periods presented, and adjust the amount of net income (loss) used in this calculation for deemed dividends and cumulative preferred stock dividends (if any), whether they are earned or not during the period. In periods of a net loss position, basic and diluted weighted average common shares are the same. For the diluted earnings per share calculation, we adjust the weighted average number of common shares outstanding to include dilutive stock options, warrants and shares associated with the conversion of convertible debt and convertible preferred stock outstanding during the periods. Year Ended Nine Months Net loss $ (7,899,001) $ (10,403,036) Less: Preferred stock beneficial conversion charge — — Undeclared cumulative preferred dividends — — Net loss attributable to common stockholders $ (7,899,001) $ (10,403,036) Weighted average common shares outstanding – basic and diluted 22,963,382 15,393,402 Basic and diluted net loss per share attributable to common stockholders $ (0.34) $ (0.68) Year Ended Nine Months Stock options 4,582,383 154,479 Warrants 4,579,699 10,710 9,162,082 165,189 We currently operate in one reportable segment and the chief operating decision maker is our Chief Executive Officer. Fair Value Measurements We measure fair value based on the prices that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. Fair value measurements are based on a three-tier hierarchy that prioritizes the inputs used to measure fair value. These tiers include the following: Level 1: Level 2: Level 3: In determining fair value, we utilize valuation techniques that maximize the use of observable inputs and minimize the use of unobservable inputs to the extent possible, as well as consider counterparty credit risk in the assessment of fair value. We have no assets or liabilities that are required to be measured at fair value on a recurring basis as of December 31, 2017 and 2016. Foreign Currency Transactions We record foreign currency transactions at the exchange rate prevailing at the date of the transaction with resultant gains and losses being included in results of operations. Foreign currency transaction gains and losses have not been significant for any of the periods presented. In May 2014, the FASB issued Accounting Standards Update (“ASU”) No. 2014-09, “Revenue from Contracts with Customers (Topic 606).” ASU 2014-09 supersedes the revenue recognition requirements in FASB Topic 605, "Revenue Recognition", and most industry-specific guidance throughout the Codification. For public companies, this standard is effective for fiscal years beginning after December 15, 2017, and for interim periods within those fiscal years. ASU 2014-09 also permits two methods of adoption: retrospectively to each prior reporting period presented (full retrospective method), or retrospectively with the cumulative effect of initially applying the guidance recognized at the date of initial application (the modified retrospective method). The Company adopted ASU 2014-09 on January 1, 2018 using the modified retrospective method. The core principle of ASU 2014-09 is that an entity should recognize revenue when it transfers promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. ASU 2014-09 defines a five step process to achieve this core principle and, in doing so, has created the possibility that more judgment and estimates may be required within the revenue recognition process than required under existing U.S. generally accepted accounting principles. We have completed our analysis on the adoption of ASU 2014-09 and have determined the adoption will not have a material impact on the recognition of revenue. However, ASU 2014-09 requires enhanced disclosures about the nature, amount, timing, and uncertainty of revenue and cash flows arising from contracts with customers, which we expect to fully disclose in connection with our 10-Q filing for the first quarter of 2018. We are in the process of implementing appropriate changes to our processes, systems and controls to support revenue recognition and the expanded qualitative and quantitative disclosures required under the new standard. In July 2015, the FASB issued ASU No. 2015-11, “Simplifying the Measurement of Inventory”. The amendments in this update apply to inventory that is measured using first-in, first-out (FIFO) or average cost. They do not apply to inventory that is measured using last-in, first-out (LIFO) or the retail inventory method. Other than the change in the subsequent measurement guidance from the lower of cost or market to the lower of cost and net realizable value for inventory within the scope of this update, there are no other substantive changes to the guidance on measurement of inventory. The amendments in this update more closely align the measurement of inventory in International Financial Reporting Standards (IFRS) and are effective for fiscal years beginning after December 15, 2016, including interim periods within those fiscal years. We adopted this guidance on January 1, 2017 and the adoption of ASU No. 2015-11 did not have an impact on our consolidated financial statements. In February 2016, the FASB issued ASU 2016-02, “Leases”, which provides for a comprehensive change to lease accounting. The new standard requires that a lessee recognize a lease obligation liability and a right-to-use asset for virtually all leases of property, plant and equipment, subsequently amortized over the lease term. The new standard is effective for fiscal years beginning after December 15, 2018, with a modified retrospective transition. Management is currently evaluating the impact this standard will have on our consolidated financial statements. In March 2016, the FASB issued ASU 2016-09, “Improvements to Employee Share-Based Payment Accounting” which simplifies several aspects of the accounting for employee share-based payment transactions, including the accounting for income taxes, forfeitures, and statutory tax withholding requirements, as well as classification in the statement of cash flows. The amendments in this ASU are effective for the reporting periods beginning after December 15, 2016 and early application is permitted. We adopted this guidance on January 1, 2017 and the adoption of ASU No. 2016-09 did not have an impact on our consolidated financial statements.

Inventories

Inventories	12 Months Ended
	Dec. 31, 2017
Inventory Disclosure [Abstract]
Inventories	Note 3. Inventories December 31, December 31, Raw materials $ 104,745 $ 58,655 Finished goods 10,051 30,844 $ 114,796 $ 89,499

Property and Equipment

Property and Equipment	12 Months Ended
	Dec. 31, 2017
Property, Plant and Equipment [Abstract]
Property and Equipment	Note 4. Property and Equipment December 31, December 31, Cryogenic shippers and data loggers $ 2,107,642 $ 1,525,409 Furniture and fixtures 63,411 59,961 Computers and software 519,198 474,681 Machinery and equipment 362,476 310,398 Leasehold improvements 436,620 426,105 Fixed assets in process 568,688 106,598 4,058,035 2,903,152 Less accumulated depreciation and amortization (1,546,861) (1,256,048) $ 2,511,174 $ 1,647,104 Total depreciation and amortization expense related to property and equipment amounted to $ 664,800 292,700

Intangible Assets

Intangible Assets	12 Months Ended
	Dec. 31, 2017
Goodwill and Intangible Assets Disclosure [Abstract]
Intangible Assets	Note 5. Intangible Assets December 31, 2017 Gross Accumulated Net Weighted Patents and trademarks $ 138,021 $ (47,375) $ 90,646 — Software development costs 545,445 (545,445) — — Total intangible assets $ 683,466 $ (592,820) $ 90,646 December 31, 2016 Gross Accumulated Net Weighted Patents and trademarks $ 52,375 $ (47,375) $ 5,000 — Software development costs 545,445 (545,445) — — Total intangible assets $ 597,820 $ (592,820) $ 5,000 Amortization expense for intangible assets for the year ended December 31, 2017 and the nine month period ended December 31, 2016 was $ 0 8,600 0

Accrued Compensation and Relate

Accrued Compensation and Related Expenses	12 Months Ended
	Dec. 31, 2017
Employee-related Liabilities [Abstract]
Accrued Compensation and Related Expenses	Note 6. Accrued Compensation and Related Expenses December 31, December 31, Accrued salaries and wages $ 617,984 $ 166,008 Accrued paid time off 307,530 207,026 Accrued board of director fees — 46,000 $ 925,514 $ 419,034

Related-Party Transactions

Related-Party Transactions	12 Months Ended
	Dec. 31, 2017
Related Party Transactions [Abstract]
Related-Party Transactions	Note 7. Related-Party Transactions As of December 31, 2016, the Company had aggregate principal balances of $ 646,700 Related-Party Notes Payable On March 1, 2016, we entered into definitive agreements with Patrick Mullens, M.D., Maryl Petreccia and Jeffrey Dell, M.D. to amend and restate the outstanding notes pursuant to certain Second Amended and Restated Promissory Notes dated as of February 29, 2016 (the “Amended and Restated Notes”). The Amended and Restated Notes increased the interest rate to 7% per annum, extended the term to April 1, 2017, and modified the repayment provisions to provide for (i) repayment on March 1, 2016 of the outstanding amount of interest accrued through February 29, 2016, (ii) repayment of 10% of the original principal balance and accrued interest of such notes on a quarterly basis commencing April 1, 2016, and (iii) payment of the remaining outstanding balance on April 1, 2017. 11,910 7,088 5,553 1.88 5,000 26,900 6,100 18,700 One note issued to Raymond Takahashi, M.D., was exchanged for (i) a new promissory note with an original principal amount equal to the outstanding principal and interest of the original note, and (ii) a warrant to purchase 1,490 6.00 February 19, 2018 35,800 Related-party interest expense under these notes was $ 9,600 39,500 0 11,400 One note issued to Marc Grossman, M.D., which as of March 31, 2016 had an outstanding principal balance of $ 6,500 6 1,000 20,000 72,000

Commitments and Contingencies

Commitments and Contingencies	12 Months Ended
	Dec. 31, 2017
Commitments and Contingencies [Abstract]
Commitments and Contingencies	Note 8. Commitments and Contingencies Facility and Equipment Leases We lease 27,600 February 28, 2023 24,700 7,600 Operating Years ending December 31, 2018 $ 405,609 2019 416,370 2020 428,868 2021 441,736 2022 454,984 Thereafter 274,405 $ 2,421,972 Rent expense for the year ended December 31, 2017 and the nine month period ended December 31, 2016 was approximately $ 298,500 222,700 Employment Agreements We have entered into employment agreements with certain of our officers under which payment and benefits would become payable in the event of termination by us for any reason other than cause, or upon a change in control of our Company, or by the employee for good reason. Consulting and Engineering Services On September 16, 2015, the Company entered into the Purchase and Sale Agreement (the “Purchase and Sale Agreement”), by and between KLATU Networks, LLC (“KLATU”) and the Company. Pursuant to the Purchase and Sale Agreement, the Company purchased from KLATU certain intellectual property and intellectual property rights related to the Company’s Cryoportal TM 400,000 200,000 Concurrently with entering into the Purchase and Sale Agreement, on September 16, 2015, the Company and KLATU entered into the Amended and Restated Master Consulting and Engineering Services Agreement (the “Amended and Restated Master Consulting and Engineering Services Agreement”) to amend and restate the Master Consulting and Engineering Services Agreement. The Amended and Restated Master Consulting and Engineering Services Agreement provides a framework for KLATU to perform certain consulting, software and hardware engineering development services as mutually agreed upon and further set forth in one or more Statements of Work (as defined in the Amended and Restated Master Consulting and Engineering Services Agreement). To ensure the availability of KLATU personnel to perform services pursuant to the Amended and Restated Master Consulting and Engineering Services Agreement, the Company agreed to pay KLATU a minimum of $ 25,000 Consulting fees for services provided by KLATU were $ 179,100 252,600 Litigation The Company may become a party to product litigation in the normal course of business. The Company accrues for open claims based on its historical experience and available insurance coverage. In the opinion of management, there are no legal matters involving the Company that would have a material adverse effect on the Company’s consolidated financial condition or results of operations. Indemnities and Guarantees The Company has made certain indemnities and guarantees, under which it may be required to make payments to a guaranteed or indemnified party, in relation to certain actions or transactions. The guarantees and indemnities do not provide for any limitation of the maximum potential future payments the Company could be obligated to make. Historically, the Company has not been obligated nor incurred any payments for these obligations and, therefore, no liabilities have been recorded for these indemnities and guarantees in the accompanying consolidated balance sheets. The Company indemnifies its directors, officers, employees and agents, as permitted under the laws of the States of California and Nevada. In connection with its facility leases, the Company has indemnified its lessors for certain claims arising from the use of the facilities. The duration of the guarantees and indemnities varies, and is generally tied to the life of the agreements.

Stockholders' Equity

Stockholders' Equity	12 Months Ended
	Dec. 31, 2017
Stockholders' Equity [Abstract]
Stockholders' Equity	Note 9. Stockholders’ Equity Authorized Stock The Company has 50,000,000 0.001 In September 2011, our stockholders approved an amendment to the Amended and Restated Articles of Incorporation to authorize a class of undesignated or "blank check" preferred stock, consisting of 2,500,000 0.001 800,000 400,000 400,000 585,000 Common Stock Issuances For Services During the year ended December 31, 2017, 15,872 70,000 During the nine months ended December 31, 2016, 19,587 47,800 Common Stock Offering On March 31, 2017, we completed an underwritten public offering (the “Offering”) for gross proceeds of $ 12.7 6,325,000 2.00 825,000 11.4 170,300 Supplemental Warrant Exercises In July 2017, the Company received proceeds of $ 1.8 605,114 As of June 27, 2017, the closing price of the Company’s common stock was equal to or exceeded $ 4.50 October 2016 Tender Offer On October 28, 2016, we completed a tender offer (the “October 2016 Tender Offer”) to holders of the Company’s outstanding warrants to purchase one share of common stock at an exercise price of $ 3.57 5,000,000 1.50 3.00 The Supplemental Warrants are exercisable upon issuance and expire on the earlier of (i) October 28, 2019 4.50 In connection with this offering, the Company incurred $ 477,300 Pursuant to the October 2016 Tender Offer, warrants to purchase 2,470,913 2,470,913 617,695 3.7 The New Warrants, which have a lower exercise price than the Original Warrants, and the Supplemental Warrants are treated as an inducement to enter into the October 2016 Tender Offer. As such, the difference between the fair value of the Original Warrants as of the date of their exchange and the fair value of the New Warrants at issuance, amounting to $ 1,649,600 615,900 2,265,400 April 2016 Tender Offer On April 7, 2016, we completed a tender offer with respect to certain warrants to purchase up to 2,448,000 Pursuant to the April 2016 Tender Offer, warrants to purchase 2,020,597 2,020,597 2.5 The warrants of holders who elected to participate in the April 2016 Tender Offer were amended to: (i) reduce the exercise price to $ 1.25 The Amended Warrants also provided that, on or prior to June 30, 2016, the Company was required to prepare and file with the SEC a registration statement on Form S-1 covering resales of the Exercise Shares. In addition, the Company was required to use commercially reasonable efforts to cause such registration statement to be declared effective by the SEC. The Company filed the Form S-1 on June 30, 2016, which was declared effective on August 10, 2016. In connection with this offering, the Company incurred $ 281,500 As a result of reducing the exercise price of certain warrants in connection with the April 2016 Tender Offer, a warrant repricing expense of $ 1,929,800 Rights Offering On June 20, 2016, we completed a rights offering for gross proceeds of $ 1.3 841,873 The rights offering was made through a distribution of non-transferable subscription rights to purchase one share of common stock for $ 1.55 85 Under the terms of the offering, rights holders had the ability to oversubscribe, which entitled each rights holder that exercised their basic subscription privilege in full the right to purchase additional shares of common stock that remained unsubscribed at the expiration of the rights offering. In connection with this offering, the Company incurred $ 315,000 Preferred Stock Conversion On January 30, 2016 (the “Mandatory Exchange Time”), the Company caused the mandatory exchange (the “Mandatory Exchange”) of all its outstanding Class A Convertible Preferred Stock and Class B Convertible Preferred Stock (together, the “Preferred Stock”), consisting of 454,750 534,571 4,977,038 0.001 4,977,038 3.57 Undeclared cumulated preferred dividends accrued during the year ended December 31, 2016 amounted to $ 75,460 Common Stock Reserved for Future Issuance 10.5 Exercise of stock options 5,322,858 Exercise of warrants 5,141,112 Total shares of common stock reserved for future issuances 10,463,970

Stock-Based Compensation

Stock-Based Compensation	12 Months Ended
	Dec. 31, 2017
Stock-Based Compensation [Abstract]
Stock-Based Compensation	Note 10. Stock-Based Compensation Warrants We typically issue warrants to purchase shares of our common stock to investors as part of a financing transaction or in connection with services rendered by placement agents and consultants. Our outstanding warrants expire on various dates through November 2021. Number of Weighted- Weighted- Aggregate Outstanding — March 31, 2016 11,153,868 3.30 Issued 795,927 2.79 Exercised (4,491,510) 1.39 Expired (10,807) 82.12 Outstanding — December 31, 2016 7,447,478 4.29 Issued — — Exercised (1,664,232) 3.25 Expired (642,134) 8.55 Outstanding — December 31, 2017 5,141,112 $ 4.09 2.3 $ 24,108,800 Vested (exercisable) — December 31, 2017 5,141,112 $ 4.09 2.3 $ 24,108,800 (1) Aggregate intrinsic value represents the difference between the exercise price of the warrant and the closing market price of the Company’s common stock on December 31, 2017, which was $ 8.59 December 31, December 31, Expected life (years) — 2.4– 5.0 Risk-free interest rate — 0.93% - 1.14% Volatility — 103% - 116% Dividend yield — 0% Exercise Price Number Weighted- Weighted- Number Weighted- $ 1.88 – 2.40 146,206 1.9 $ 2.17 146,206 $ 2.17 $ 3.57 – 3.57 3,836,793 2.6 $ 3.57 3,836,793 $ 3.57 $ 4.44 – 4.47 599,898 0.8 $ 4.44 599,898 $ 4.44 $ 5.88 – 6.00 547,323 1.9 $ 6.00 547,323 $ 6.00 $61.20 – 129.60 10,892 0.7 $ 99.97 10,892 $ 99.97 5,141,112 5,141,112 During the year ended December 31, 2017, the Company issued 1,403,149 4.5 144,164 261,083 The total intrinsic value of warrants exercised during the year ended December 31, 2017 and the nine months ended December 31, 2016 was $ 7.1 3.2 Stock Options We have four stock incentive plans: the 2002 Stock Incentive Plan (the “2002 Plan”), the 2009 Stock Incentive Plan (the “2009 Plan”), the 2011 Stock Incentive Plan (the “2011 Plan”) and the 2015 Omnibus Equity Incentive Plan (the “2015 Plan”), (collectively, the “Plans”). The 2002 Plan, the 2009 Plan, and the 2011 Plan (collectively the “Prior Plans”) have been superseded by the 2015 Plan. In October 2015, the stockholders approved the 2015 Plan for 5,000,000 1,339,909 December 31, December 31, Expected life (years) 5.3 – 6.6 6.0 – 6.1 Risk-free interest rate 1.79% - 2.23% 1.17% - 2.09% Volatility 111% - 115% 113% - 118% Dividend yield 0% 0% The expected option life assumption is estimated based on the simplified method. Accordingly, the Company has utilized the average of the contractual term of the options and the weighted average vesting period for all options to calculate the expected option term. The risk-free interest rate assumption is based upon observed interest rates appropriate for the expected term of our employee stock options. The expected volatility is based on the historical volatility of our stock commensurate with the expected life of the stock-based award. We do not anticipate paying dividends on the common stock in the foreseeable future. We recognize stock-based compensation cost over the vesting period using the straight-line single option method. Stock-based compensation expense is recognized only for those awards that ultimately vest. Year Ended Nine Months Ended 2017 2016 Cost of revenues $ 43,349 $ 18,355 General and administrative 2,689,496 1,791,981 Sales and marketing 723,648 510,078 Engineering and development 91,288 8,589 $ 3,547,781 $ 2,329,003 Number of Weighted- Weighted- Aggregate Outstanding — March 31, 2016 3,999,325 $ 4.44 Granted (weighted-average fair value of $1.62 per share) 892,774 1.89 Exercised - - Forfeited (294,799) 3.28 Expired (84,750) 4.61 Outstanding — December 31, 2016 4,512,550 $ 4.01 Granted (weighted-average fair value of $3.85 per share) 1,176,300 4.59 Exercised (209,456) 3.09 Forfeited (101,199) 3.04 Expired (55,357) 7.89 Outstanding — December 31, 2017 5,322,858 $ 4.16 7.7 $ 23,718,000 Vested (exercisable) — December 31, 2017 2,871,876 $ 4.16 7.1 $ 12,751,500 Expected to vest after December 31, 2017 (unexercisable) 2,450,982 $ 4.16 8.4 $ 10,966,500 (1) Aggregate intrinsic value represents the difference between the exercise price of the option and the closing market price of the common stock on December 31, 2017, which was $8.59 per share. Exercise Price Number Weighted- Weighted- Number Weighted- $1.08 – 2.66 920,102 7.9 $ 1.88 430,510 $ 1.98 $3.00 – 3.96 1,976,705 7.8 $ 3.20 1,020,669 $ 3.17 $4.80 – 4.92 835,628 7.3 $ 4.77 587,815 $ 4.77 $5.00 – 6.65 956,471 7.6 $ 5.09 541,682 $ 5.06 $7.80 – 7.89 442,451 7.4 $ 7.80 278,699 $ 7.80 $8.20 – 22.68 191,501 9.4 $ 9.34 12,501 $ 12.02 5,322,858 2,871,876 As of December 31, 2017, there was unrecognized compensation expense of $ 7.4 2.4 The total intrinsic value of options exercised during the year ended December 31, 2017 was $ 797,600

Income Taxes

Income Taxes	12 Months Ended
	Dec. 31, 2017
Income Tax Disclosure [Abstract]
Income Taxes	Note 11. Income Taxes December 31, December 31, (000’s) Deferred tax assets: Net operating loss carryforward $ 15,307 $ 20,668 Research credits 100 56 Expenses recognized for granting of options and warrants 2,014 2,316 Accrued expenses and reserves 41 43 Valuation allowance (17,462) (23,083) $ — $ — Based on the weight of available evidence, the Company’s management has determined that it is more likely than not that the net deferred tax assets will not be realized. Therefore, the Company has recorded a full valuation allowance against the net deferred tax assets. The Company’s income tax provision consists of state minimum taxes. December 31, December 31, (000’s) Computed tax benefit at federal statutory rate $ (2,684) $ (3,535) State tax, net of federal benefit (277) (196) Stock compensation 503 607 Warrant inducement and repricing costs — 1,426 Permanent items and other 56 41 Tax Cuts and Jobs Act 8,032 — Valuation allowance (5,625) 1,663 $ 5 $ 6 At December 31, 2017, the Company has federal and state net operating loss carryforwards of approximately $ 58,490,000 46,573,000 53,000 45,000 Utilization of the net operating loss and research and development carryforwards might be subject to a substantial annual limitation due to ownership change limitations that may have occurred or that could occur in the future, as required by Section 382 of the Internal Revenue Code of 1986, as amended (the “Code”), as well as similar state and foreign provisions. These ownership changes may limit the amount of NOL and R&D credit carryforwards that can be utilized annually to offset future taxable income and tax, respectively. In general, an “ownership change” as defined by Section 382 of the Code results from a transaction or series of transactions over a three-year period resulting in an ownership change of more than 50 percentage points of the outstanding stock of a company by certain stockholders or public groups. Since the Company’s formation, the Company has raised capital through the issuance of capital stock on several occasions which, combined with the purchasing stockholders’ subsequent disposition of those shares, may have resulted in such an ownership change, or could result in an ownership change in the future upon subsequent disposition. The Company has not completed a study to assess whether an ownership change has occurred. If the Company has experienced an ownership change, utilization of the NOL or R&D credit carryforwards would be subject to an annual limitation under Section 382 of the Code, which is determined by first multiplying the value of the Company’s stock at the time of the ownership change by the applicable long-term, tax-exempt rate, and then could be subject to additional adjustments, as required. Any limitation may result in expiration of a portion of the NOL or R&D credit carryforwards before utilization. Further, until a study is completed and any limitation is known, no amounts are being considered as an uncertain tax position or disclosed as an unrecognized tax benefit. Due to the existence of the valuation allowance, future changes in the Company’s unrecognized tax benefits will not impact its effective tax rate. Any carryforwards that will expire prior to utilization as a result of such limitations will be removed from deferred tax assets with a corresponding reduction of the valuation allowance. Federal State December 31, December 31, 2017 2016 2017 2016 Unrecognized tax positions, beginning of period - - - - Gross increase – current period tax positions 7 - 7 - Gross decrease – prior period tax positions - - - - Gross increase – prior period tax positions 6 - 4 - Expiration of statute of limitations - - - - Unrecognized tax positions, end of period $ 13 $ - $ 11 $ - If recognized, none of the unrecognized tax positions would impact the Company's income tax benefit or effective tax rate as long as the Company's deferred tax assets remain subject to a full valuation allowance. The Company does not expect any significant increases or decreases to the Company's unrecognized tax positions within the next 12 months. On December 22, 2017, the President of the United States signed into law the Tax Cuts and Jobs Act (the "Tax Act"). The Tax Act amends the Internal Revenue Code to reduce tax rates and modify policies, credits, and deductions for individuals and businesses. For businesses, the Tax Act reduces the corporate tax rate from a maximum of 35 21 8.0 Due to uncertainties which currently exist in the interpretation of the provisions of the Tax Act regarding Internal Revenue Code Section 162(m), the Company has not evaluated the potential impacts of IRC Section 162(m) as amended by the Tax Act on its consolidated financial statements. In conjunction with the Tax Act, the SEC staff issued Staff Accounting Bulletin No. 118 ("SAB 118") to address the application of U.S. GAAP in situations when a registrant does not have the necessary information available, prepared, or analyzed (including computations) in reasonable detail to complete the accounting for certain income tax effects of the Tax Act. The Company has recognized the provisional tax impacts related to the revaluation of deferred tax assets and liabilities at December 31, 2017. There was no net impact on the Company's consolidated financial statements for the year ended December 31, 2017 as the corresponding adjustment was made to the valuation allowance. The ultimate impact may differ from these provisional amounts, possibly materially, due to, among other things, additional analysis, changes in interpretations and assumptions the Company has made, additional regulatory guidance that may be issued, and actions the Company may take as a result of the Tax Act.

Quarterly Financial Data

Quarterly Financial Data	12 Months Ended
	Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract]
Quarterly Financial Data	Note 12. Quarterly Financial Data (Unaudited) Quarter Ended March 31 June 30 September 30 December 31 Year ended December 31, 2017 Total revenues $ 2,712 $ 2,917 $ 3,003 $ 3,322 Gross margin $ 1,253 $ 1,393 $ 1,606 $ 1,713 Loss from operations $ (1,769) $ (1,864) $ (1,988) $ (2,271) Net loss $ (1,789) $ (1,860) $ (1,980) $ (2,270) Net loss per share attributable to common stockholders - basic and diluted $ (0.10) $ (0.08) $ (0.08) $ (0.09) Nine months ended December 31, 2016 Total revenues $ — $ 1,918 $ 1,977 $ 2,229 Gross margin $ — $ 782 $ 797 $ 941 Loss from operations $ — $ (1,979) $ (2,161) $ (2,002) Net loss $ — $ (3,935) $ (2,184) $ (4,284) Net loss per share attributable to common stockholders - basic and diluted $ — $ (0.28) $ (0.14) $ (0.25) Earnings per basic and diluted shares are computed independently for each of the quarters presented based on basic and diluted shares outstanding per quarter and, therefore, may not sum to the totals for the periods shown.

Subsequent Event

Subsequent Event	12 Months Ended
	Dec. 31, 2017
Subsequent Events [Abstract]
Subsequent Event	Note 13. Subsequent Event February 2018 Tender Offer On February 8, 2018, we completed an exchange offer with respect to the Company’s outstanding warrants to purchase one share of common stock at an exercise price of $ 3.57 3.00 Pursuant to the February 2018 Tender Offer, warrants to purchase 1,580,388 4.7 The Original Warrants were issued (i) in July 2015 in connection with the Company’s registered public offering of 2,090,750 4,977,038 3,836,793 The terms of the New Warrants included (i) an exercise price of $3.00 per share and (ii) an exercise period that expired concurrently with the expiration of the Offer at 5:00 p.m. (Eastern Time) on February 2, 2018 (the “Expiration Date”). In addition, the shares issuable upon exercise of the New Warrants (the “New Warrant Shares”) are subject to a 60-day lock-up period. The purpose of the Offer was to raise funds to support the Company’s growth plans by providing the holders of the Original Warrants an incentive to exchange their Original Warrants for New Warrants and exercise the New Warrants to purchase shares of the Company’s common stock at a reduced exercise price as compared to the Original Warrants. The Company received all of the proceeds from the immediate exercise of the New Warrants, which will be used by the Company for business growth, including as working capital and for other general corporate purposes. As a result of reducing the exercise price of certain warrants in connection with the February 2018 Tender Offer, a warrant repricing expense of $ 899,400 99,400

Summary of Significant Accoun21

Summary of Significant Accounting Policies (Policies)	12 Months Ended
	Dec. 31, 2017
Summary of Significant Accounting Policies [Abstract]
Basis of Presentation	The accompanying consolidated financial statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”). In September 2016, the Company elected to change its fiscal year end from March 31 to a new fiscal year end of December 31. Accordingly, the accompanying consolidated financial statements include audited financial statements for the year ended December 31, 2017 and the nine-month transition period ended December 31, 2016 and unaudited financial statements for the year ended December 31, 2016. As a result of the change, the Company’s quarterly reporting periods are comprised of the three calendar months ending March 31, June 30 and September 30.
Principles of Consolidation	Principles of Consolidation The accompanying consolidated financial statements include the accounts of Cryoport, Inc. and its wholly owned subsidiaries, Cryoport Systems, Inc. and Cryoport Europe Limited (collectively, the “Company”). All intercompany accounts and transactions have been eliminated.
Use of Estimates	Use of Estimates The preparation of the consolidated financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the consolidated financial statements and the reported amounts of revenues and expenses during the reporting periods. Actual results could differ from estimated amounts. The Company’s significant estimates include the allowance for doubtful accounts, recoverability of long-lived assets, allowance for inventory obsolescence, deferred taxes and their accompanying valuations, and valuation of equity instruments.
Fair Value of Financial Instruments	Fair Value of Financial Instruments The Company’s financial instruments consist of cash and cash equivalents, accounts receivable, related-party notes payable, accounts payable and accrued expenses. The carrying value for all such instruments, except for related-party notes payable, approximates fair value at December 31, 2017 and 2016 due to their short-term nature. The difference between the fair value and recorded values of the related-party notes payable is not significant.
Cash and Cash Equivalents	Cash and Cash Equivalents The Company considers highly liquid investments with original maturities of 90
Concentrations of Credit Risk	Concentrations of Credit Risk The Company maintains its cash accounts in financial institutions. Accounts at these institutions are insured by the Federal Deposit Insurance Corporation (“FDIC”) with basic deposit insurance coverage limits up to $ 250,000 14.8
Customers	Customers The Company grants credit to customers within the U.S. and to a limited number of international customers and does not require collateral. Revenues from international customers are generally secured by advance payments except for a limited number of established foreign customers. The Company generally requires advance or credit card payments for initial revenues from new customers. The Company’s ability to collect receivables is affected by economic fluctuations in the geographic areas and industries served by the Company. Reserves for uncollectible amounts are provided based on past experience and a specific analysis of the accounts, which management believes is sufficient. Accounts receivable at December 31, 2017 and 2016 are net of reserves for doubtful accounts of $ 70,000 75,000 The majority of the Company’s customers are in the biotechnology, pharmaceutical and life science industries. Consequently, there is a concentration of accounts receivable within these industries, which is subject to normal credit risk. No single customer owed the Company more than 10 The Company has revenue from foreign customers primarily in Europe, Japan, Canada, India and Australia. During the year ended December 31, 2017 and the nine-month transition period ended December 31, 2016, the Company had revenues from foreign customers of approximately $ 1.3 750,400 11.0 12.3 10
Inventories	Inventories The Company’s inventories consist of packaging materials and accessories that are sold to customers. Inventories are stated at the lower of cost and net realizable value. Cost is determined using the standard cost method which approximates the first-in, first-to-expire method. Inventories are reviewed periodically for slow-moving or obsolete status. The Company writes down the carrying value of its inventories to reflect situations in which the cost of inventories is not expected to be recovered. Once established, write-downs of inventories are considered permanent adjustments to the cost basis of the obsolete or excess inventories. Raw materials and finished goods include material costs less reserves for obsolete or excess inventories. The Company evaluates the current level of inventories considering historical trends and other factors, such as selling prices and costs of completion, disposal and transportation, and based on the evaluation, records adjustments to reflect inventories at net realizable value. These adjustments are estimates, which could vary significantly from actual results if future economic conditions, customer demand, competition or other relevant factors differ from expectations. These estimates require us to make assessments about future demand for the Company’s products in order to categorize the status of such inventories items as slow-moving, obsolete or in excess-of-need. These estimates are subject to the ongoing accuracy of the Company’s forecasts of market conditions, industry trends, competition and other factors.
Property and Equipment	Property and Equipment The Company provides shipping containers to its customers and charges a fee in exchange for the use of the container. The Company’s arrangements are similar to the accounting standard for leases since they convey the right to use the container over a period of time. The Company retains the title to the containers and provides its customers the use of the container for a specific shipping cycle. At the culmination of the customer’s shipping cycle, the container is returned to the Company. As a result, the Company classifies the containers as property and equipment for the per-use container program. Property and equipment are recorded at cost. Cryogenic shippers and data loggers, which comprise 47 44 Betterments, renewals and extraordinary repairs that extend the lives of the assets are capitalized; other repairs and maintenance charges are expensed as incurred. The cost and related accumulated depreciation and amortization applicable to assets retired are removed from the accounts, and the gain or loss on disposition is recognized in the consolidated statements of operations.
Intangible Assets	Intangible Assets Intangible assets are comprised of patents and trademarks and software development costs. The Company capitalizes costs of obtaining patents and trademarks, which are amortized, using the straight-line method over their estimated useful life of five years once the patent or trademark has been issued. The Company capitalizes certain costs related to software developed for internal use. Software development costs incurred during the preliminary or maintenance project stages are expensed as incurred, while costs incurred during the application development stage are capitalized and amortized using the straight-line method over the estimated useful life of the software, which is five years. Capitalized costs include purchased materials and costs of services.
Long-lived Assets	Long-lived Assets If indicators of impairment exist, we assess the recoverability of the affected long-lived assets by determining whether the carrying value of such assets can be recovered through undiscounted future operating cash flows. If impairment is indicated, we measure the amount of such impairment by comparing the fair value to the carrying value. We believe the future cash flows to be received from the long-lived assets will exceed the assets’ carrying value, and accordingly, we have not recognized any impairment losses through December 31, 2017.
Deferred Financing Costs	Deferred Financing Costs Deferred financing costs represent costs incurred in connection with the issuance of the debt instruments and equity financings. Deferred financing costs related to the issuance of debt are amortized over the term of the financing instrument using the effective interest method while offering costs from equity financings are netted against the gross proceeds received from the equity financings.
Income Taxes	Income Taxes The Company accounts for income taxes under the provision of the Financial Accounting Standards Board (“FASB”) Accounting Standards Codification (“ASC”) 740, Income Taxes Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment date. A valuation allowance is provided for certain deferred tax assets if it is more likely than not that the Company will not realize tax assets through future operations. Based on the weight of available evidence, the Company’s management has determined that it is more likely than not that the net deferred tax assets will not be realized. Therefore, the Company has recorded a full valuation allowance against the net deferred tax assets. The Company’s provision for income taxes consists of state minimum taxes. The Company’s policy is to recognize interest and/or penalties related to income tax matters in income tax expense. The Company had no accrual for interest or penalties on its consolidated balance sheets at December 31, 2017 and 2016 and has not recognized interest and/or penalties in the consolidated statements of operations for the year ended December 31, 2017 and the nine months ended December 31, 2016. The Company is subject to taxation in the U.S. and various state jurisdictions. As of December 31, 2017, the Company is no longer subject to U.S. federal examinations for years before 2014 and for California franchise and income tax examinations for years before 2013. However, to the extent allowed by law, the taxing authorities may have the right to examine prior periods where net operating losses were generated and carried forward, and make adjustments up to the amount of the net operating loss carry forward amount. The Company is not currently under examination by U.S. federal or state jurisdictions.
Revenue Recognition	Revenue Recognition The Company provides shipping containers to its customers and charges a fee in exchange for the use of the containers. The Company’s arrangements are similar to the accounting standard for leases since they convey the right to use the containers over a period of time. The Company retains title to the containers and provides its customers the use of the containers for a specified shipping cycle. At the culmination of the customer’s shipping cycle, the container is returned to the Company. The Company recognizes revenue for the use of the shipper at the time of the delivery of the shipper to the end user of the enclosed materials, and at the time that collectability is reasonably certain. Revenue is based on gross amounts, net of discounts and allowances. The Company also provides logistics support and management services to some customers, which may include onsite logistics personnel. Revenue is recognized for these services as services are rendered and at the time that collectability is reasonably certain.
Accounting for Shipping and Handling Revenue, Fees and Costs	Accounting for Shipping and Handling Revenue, Fees and Costs The Company classifies amounts billed for shipping and handling as revenue. Shipping and handling fees and costs are included in cost of revenues in the accompanying consolidated statements of operations.
Research and Development Expenses	Engineering and Development Expenses Expenditures relating to engineering and development are expensed in the period incurred.
Stock-Based Compensation	Stock-Based Compensation The Company accounts for stock-based payments to employees and directors in accordance with stock-based payment accounting guidance which requires all stock-based payments to employees and directors, including grants of employee stock options and warrants, to be recognized based upon their estimated fair values. The fair value of stock-based awards is estimated at grant date using the Black-Scholes Option Pricing Method (“Black-Scholes”) and the portion that is ultimately expected to vest is recognized as compensation cost over the requisite service period. The Company accounts for forfeitures of unvested awards as they occur. The Company uses Black-Scholes to estimate the fair value of stock-based awards. The determination of fair value using Black-Scholes is affected by the Company’s stock price as well as assumptions regarding a number of complex and subjective variables, including expected stock price volatility, risk-free interest rate, expected dividends and projected employee stock option exercise behaviors. The Company’s stock-based compensation plans are discussed further in Note 10.
Equity Instruments Issued to Non-Employees for Acquiring Goods or Services	Equity Instruments Issued to Non-Employees for Acquiring Goods or Services Issuances of the Company’s common stock for acquiring goods or services are measured at the estimated fair value of the consideration received or the estimated fair value of the equity instruments issued, whichever is more reliably measurable. The measurement date for the estimated fair value of the equity instruments issued to consultants or vendors is determined at the earlier of (i) the date at which a commitment for performance to earn the equity instruments is reached (a “performance commitment” which would include a penalty considered to be of a magnitude that is a sufficiently large disincentive for nonperformance) or (ii) the date at which performance is complete. When it is appropriate for the Company to recognize the cost of a transaction during financial reporting periods prior to the measurement date, for purposes of recognition of costs during those periods, the equity instrument is measured at the then-current estimated fair values at each of those interim financial reporting dates.
Basic and Diluted Net Income (Loss) Per Share	Basic and Diluted Net Income (Loss) Per Share We calculate basic and diluted net income (loss) per share attributable to common stockholders using the weighted average number of common shares outstanding during the periods presented, and adjust the amount of net income (loss) used in this calculation for deemed dividends and cumulative preferred stock dividends (if any), whether they are earned or not during the period. In periods of a net loss position, basic and diluted weighted average common shares are the same. For the diluted earnings per share calculation, we adjust the weighted average number of common shares outstanding to include dilutive stock options, warrants and shares associated with the conversion of convertible debt and convertible preferred stock outstanding during the periods. Year Ended Nine Months Net loss $ (7,899,001) $ (10,403,036) Less: Preferred stock beneficial conversion charge — — Undeclared cumulative preferred dividends — — Net loss attributable to common stockholders $ (7,899,001) $ (10,403,036) Weighted average common shares outstanding – basic and diluted 22,963,382 15,393,402 Basic and diluted net loss per share attributable to common stockholders $ (0.34) $ (0.68) Year Ended Nine Months Stock options 4,582,383 154,479 Warrants 4,579,699 10,710 9,162,082 165,189
Segment Reporting	Segment Reporting We currently operate in one reportable segment and the chief operating decision maker is our Chief Executive Officer.
Fair Value Measurements	Fair Value Measurements We measure fair value based on the prices that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. Fair value measurements are based on a three-tier hierarchy that prioritizes the inputs used to measure fair value. These tiers include the following: Level 1: Level 2: Level 3: In determining fair value, we utilize valuation techniques that maximize the use of observable inputs and minimize the use of unobservable inputs to the extent possible, as well as consider counterparty credit risk in the assessment of fair value. We have no assets or liabilities that are required to be measured at fair value on a recurring basis as of December 31, 2017 and 2016.
Foreign Currency Transactions	Foreign Currency Transactions We record foreign currency transactions at the exchange rate prevailing at the date of the transaction with resultant gains and losses being included in results of operations. Foreign currency transaction gains and losses have not been significant for any of the periods presented.
Recent Accounting Pronouncements	Recent Accounting Pronouncements In May 2014, the FASB issued Accounting Standards Update (“ASU”) No. 2014-09, “Revenue from Contracts with Customers (Topic 606).” ASU 2014-09 supersedes the revenue recognition requirements in FASB Topic 605, "Revenue Recognition", and most industry-specific guidance throughout the Codification. For public companies, this standard is effective for fiscal years beginning after December 15, 2017, and for interim periods within those fiscal years. ASU 2014-09 also permits two methods of adoption: retrospectively to each prior reporting period presented (full retrospective method), or retrospectively with the cumulative effect of initially applying the guidance recognized at the date of initial application (the modified retrospective method). The Company adopted ASU 2014-09 on January 1, 2018 using the modified retrospective method. The core principle of ASU 2014-09 is that an entity should recognize revenue when it transfers promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. ASU 2014-09 defines a five step process to achieve this core principle and, in doing so, has created the possibility that more judgment and estimates may be required within the revenue recognition process than required under existing U.S. generally accepted accounting principles. We have completed our analysis on the adoption of ASU 2014-09 and have determined the adoption will not have a material impact on the recognition of revenue. However, ASU 2014-09 requires enhanced disclosures about the nature, amount, timing, and uncertainty of revenue and cash flows arising from contracts with customers, which we expect to fully disclose in connection with our 10-Q filing for the first quarter of 2018. We are in the process of implementing appropriate changes to our processes, systems and controls to support revenue recognition and the expanded qualitative and quantitative disclosures required under the new standard. In July 2015, the FASB issued ASU No. 2015-11, “Simplifying the Measurement of Inventory”. The amendments in this update apply to inventory that is measured using first-in, first-out (FIFO) or average cost. They do not apply to inventory that is measured using last-in, first-out (LIFO) or the retail inventory method. Other than the change in the subsequent measurement guidance from the lower of cost or market to the lower of cost and net realizable value for inventory within the scope of this update, there are no other substantive changes to the guidance on measurement of inventory. The amendments in this update more closely align the measurement of inventory in International Financial Reporting Standards (IFRS) and are effective for fiscal years beginning after December 15, 2016, including interim periods within those fiscal years. We adopted this guidance on January 1, 2017 and the adoption of ASU No. 2015-11 did not have an impact on our consolidated financial statements. In February 2016, the FASB issued ASU 2016-02, “Leases”, which provides for a comprehensive change to lease accounting. The new standard requires that a lessee recognize a lease obligation liability and a right-to-use asset for virtually all leases of property, plant and equipment, subsequently amortized over the lease term. The new standard is effective for fiscal years beginning after December 15, 2018, with a modified retrospective transition. Management is currently evaluating the impact this standard will have on our consolidated financial statements. In March 2016, the FASB issued ASU 2016-09, “Improvements to Employee Share-Based Payment Accounting” which simplifies several aspects of the accounting for employee share-based payment transactions, including the accounting for income taxes, forfeitures, and statutory tax withholding requirements, as well as classification in the statement of cash flows. The amendments in this ASU are effective for the reporting periods beginning after December 15, 2016 and early application is permitted. We adopted this guidance on January 1, 2017 and the adoption of ASU No. 2016-09 did not have an impact on our consolidated financial statements.

Summary of Significant Accoun22

Summary of Significant Accounting Policies (Tables)	12 Months Ended
	Dec. 31, 2017
Summary of Significant Accounting Policies [Abstract]
Schedule of Earnings Per Share	Year Ended Nine Months Net loss $ (7,899,001) $ (10,403,036) Less: Preferred stock beneficial conversion charge — — Undeclared cumulative preferred dividends — — Net loss attributable to common stockholders $ (7,899,001) $ (10,403,036) Weighted average common shares outstanding – basic and diluted 22,963,382 15,393,402 Basic and diluted net loss per share attributable to common stockholders $ (0.34) $ (0.68)
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share	The following table sets forth the number of shares excluded from the computation of diluted loss per share, as their inclusion would have been anti-dilutive: Year Ended Nine Months Stock options 4,582,383 154,479 Warrants 4,579,699 10,710 9,162,082 165,189

Inventories (Tables)

Inventories (Tables)	12 Months Ended
	Dec. 31, 2017
Inventory Disclosure [Abstract]
Schedule of Utility Inventory	Inventories consist of the following: December 31, December 31, Raw materials $ 104,745 $ 58,655 Finished goods 10,051 30,844 $ 114,796 $ 89,499

Property and Equipment (Tables)

Property and Equipment (Tables)	12 Months Ended
	Dec. 31, 2017
Property, Plant and Equipment [Abstract]
Schedule of Property, Plant and Equipment	Property and equipment consist of the following: December 31, December 31, Cryogenic shippers and data loggers $ 2,107,642 $ 1,525,409 Furniture and fixtures 63,411 59,961 Computers and software 519,198 474,681 Machinery and equipment 362,476 310,398 Leasehold improvements 436,620 426,105 Fixed assets in process 568,688 106,598 4,058,035 2,903,152 Less accumulated depreciation and amortization (1,546,861) (1,256,048) $ 2,511,174 $ 1,647,104

Intangible Assets (Tables)

Intangible Assets (Tables)	12 Months Ended
	Dec. 31, 2017
Goodwill and Intangible Assets Disclosure [Abstract]
Schedule of Finite-Lived Intangible Assets	Intangible assets consist of the following: December 31, 2017 Gross Accumulated Net Weighted Patents and trademarks $ 138,021 $ (47,375) $ 90,646 — Software development costs 545,445 (545,445) — — Total intangible assets $ 683,466 $ (592,820) $ 90,646 December 31, 2016 Gross Accumulated Net Weighted Patents and trademarks $ 52,375 $ (47,375) $ 5,000 — Software development costs 545,445 (545,445) — — Total intangible assets $ 597,820 $ (592,820) $ 5,000

Accrued Compensation and Rela26

Accrued Compensation and Related Expenses (Tables)	12 Months Ended
	Dec. 31, 2017
Employee-related Liabilities [Abstract]
Schedule of employee related liabilities	Accrued compensation and related expenses consist of the following: December 31, December 31, Accrued salaries and wages $ 617,984 $ 166,008 Accrued paid time off 307,530 207,026 Accrued board of director fees — 46,000 $ 925,514 $ 419,034

Commitments and Contingencies (

Commitments and Contingencies (Tables)	12 Months Ended
	Dec. 31, 2017
Commitments and Contingencies [Abstract]
Schedule of Future Minimum Rental Payments for Operating Leases	Future minimum lease payments are approximately as follows: Operating Years ending December 31, 2018 $ 405,609 2019 416,370 2020 428,868 2021 441,736 2022 454,984 Thereafter 274,405 $ 2,421,972

Stockholders' Equity (Tables)

Stockholders' Equity (Tables)	12 Months Ended
	Dec. 31, 2017
Stockholders' Equity [Abstract]
Schedule of Common Stock Reserved for Future Issuance	As of December 31, 2017, approximately 10.5 Exercise of stock options 5,322,858 Exercise of warrants 5,141,112 Total shares of common stock reserved for future issuances 10,463,970

Stock-Based Compensation (Table

Stock-Based Compensation (Tables)	12 Months Ended
	Dec. 31, 2017
Schedule of Warrant Activity	A summary of warrant activity is as follows: Number of Weighted- Weighted- Aggregate Outstanding — March 31, 2016 11,153,868 3.30 Issued 795,927 2.79 Exercised (4,491,510) 1.39 Expired (10,807) 82.12 Outstanding — December 31, 2016 7,447,478 4.29 Issued — — Exercised (1,664,232) 3.25 Expired (642,134) 8.55 Outstanding — December 31, 2017 5,141,112 $ 4.09 2.3 $ 24,108,800 Vested (exercisable) — December 31, 2017 5,141,112 $ 4.09 2.3 $ 24,108,800 (1) Aggregate intrinsic value represents the difference between the exercise price of the warrant and the closing market price of the Company’s common stock on December 31, 2017, which was $ 8.59
Schedule of Fair Value Assumptions of Stock Options	The fair value of each option grant was estimated on the date of grant using Black-Scholes with the following assumptions: December 31, December 31, Expected life (years) 5.3 – 6.6 6.0 – 6.1 Risk-free interest rate 1.79% - 2.23% 1.17% - 2.09% Volatility 111% - 115% 113% - 118% Dividend yield 0% 0%
Schedule of Share-based Payment Awards	Total stock-based compensation expense related to all of our share-based payment awards is comprised of the following: Year Ended Nine Months Ended 2017 2016 Cost of revenues $ 43,349 $ 18,355 General and administrative 2,689,496 1,791,981 Sales and marketing 723,648 510,078 Engineering and development 91,288 8,589 $ 3,547,781 $ 2,329,003
Schedule of Stock Option Activity	Number of Weighted- Weighted- Aggregate Outstanding — March 31, 2016 3,999,325 $ 4.44 Granted (weighted-average fair value of $1.62 per share) 892,774 1.89 Exercised - - Forfeited (294,799) 3.28 Expired (84,750) 4.61 Outstanding — December 31, 2016 4,512,550 $ 4.01 Granted (weighted-average fair value of $3.85 per share) 1,176,300 4.59 Exercised (209,456) 3.09 Forfeited (101,199) 3.04 Expired (55,357) 7.89 Outstanding — December 31, 2017 5,322,858 $ 4.16 7.7 $ 23,718,000 Vested (exercisable) — December 31, 2017 2,871,876 $ 4.16 7.1 $ 12,751,500 Expected to vest after December 31, 2017 (unexercisable) 2,450,982 $ 4.16 8.4 $ 10,966,500 (1) Aggregate intrinsic value represents the difference between the exercise price of the option and the closing market price of the common stock on December 31, 2017, which was $8.59 per share.
Stock Options [Member]
Schedule of Information by Exercise Price Range	The following table summarizes information with respect to stock options outstanding and exercisable at December 31, 2017: Exercise Price Number Weighted- Weighted- Number Weighted- $1.08 – 2.66 920,102 7.9 $ 1.88 430,510 $ 1.98 $3.00 – 3.96 1,976,705 7.8 $ 3.20 1,020,669 $ 3.17 $4.80 – 4.92 835,628 7.3 $ 4.77 587,815 $ 4.77 $5.00 – 6.65 956,471 7.6 $ 5.09 541,682 $ 5.06 $7.80 – 7.89 442,451 7.4 $ 7.80 278,699 $ 7.80 $8.20 – 22.68 191,501 9.4 $ 9.34 12,501 $ 12.02 5,322,858 2,871,876
Warrant [Member]
Schedule of Fair Value Assumptions of Stock Options	During the year ended December 31, 2017 and the nine months ended December 31, 2016, the fair value of each warrant grant was estimated on the date of grant using Black-Scholes with the following assumptions: December 31, December 31, Expected life (years) — 2.4– 5.0 Risk-free interest rate — 0.93% - 1.14% Volatility — 103% - 116% Dividend yield — 0%
Schedule of Information by Exercise Price Range	The following table summarizes information with respect to warrants outstanding and exercisable at December 31, 2017: Exercise Price Number Weighted- Weighted- Number Weighted- $ 1.88 – 2.40 146,206 1.9 $ 2.17 146,206 $ 2.17 $ 3.57 – 3.57 3,836,793 2.6 $ 3.57 3,836,793 $ 3.57 $ 4.44 – 4.47 599,898 0.8 $ 4.44 599,898 $ 4.44 $ 5.88 – 6.00 547,323 1.9 $ 6.00 547,323 $ 6.00 $61.20 – 129.60 10,892 0.7 $ 99.97 10,892 $ 99.97 5,141,112 5,141,112

Income Taxes (Tables)

Income Taxes (Tables)	12 Months Ended
	Dec. 31, 2017
Income Tax Disclosure [Abstract]
Schedule of Deferred Tax Assets	Significant components of the Company’s deferred tax assets as of December 31, 2017 and 2016 are shown below: December 31, December 31, (000’s) Deferred tax assets: Net operating loss carryforward $ 15,307 $ 20,668 Research credits 100 56 Expenses recognized for granting of options and warrants 2,014 2,316 Accrued expenses and reserves 41 43 Valuation allowance (17,462) (23,083) $ — $ —
Schedule of Components of Income Tax Expense (Benefit)	The provision for income taxes differs from that computed using the federal statutory rate applied to income before taxes as follows: December 31, December 31, (000’s) Computed tax benefit at federal statutory rate $ (2,684) $ (3,535) State tax, net of federal benefit (277) (196) Stock compensation 503 607 Warrant inducement and repricing costs — 1,426 Permanent items and other 56 41 Tax Cuts and Jobs Act 8,032 — Valuation allowance (5,625) 1,663 $ 5 $ 6
Schedule of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns	A reconciliation of the beginning and ending amounts of unrecognized tax positions are as follows (in thousands): Federal State December 31, December 31, 2017 2016 2017 2016 Unrecognized tax positions, beginning of period - - - - Gross increase – current period tax positions 7 - 7 - Gross decrease – prior period tax positions - - - - Gross increase – prior period tax positions 6 - 4 - Expiration of statute of limitations - - - - Unrecognized tax positions, end of period $ 13 $ - $ 11 $ -

Quarterly Financial Data (Table

Quarterly Financial Data (Tables)	12 Months Ended
	Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract]
Schedule of Quarterly Financial Information	A summary of quarterly financial data is as follows ($ in ‘000’s): Quarter Ended March 31 June 30 September 30 December 31 Year ended December 31, 2017 Total revenues $ 2,712 $ 2,917 $ 3,003 $ 3,322 Gross margin $ 1,253 $ 1,393 $ 1,606 $ 1,713 Loss from operations $ (1,769) $ (1,864) $ (1,988) $ (2,271) Net loss $ (1,789) $ (1,860) $ (1,980) $ (2,270) Net loss per share attributable to common stockholders - basic and diluted $ (0.10) $ (0.08) $ (0.08) $ (0.09) Nine months ended December 31, 2016 Total revenues $ — $ 1,918 $ 1,977 $ 2,229 Gross margin $ — $ 782 $ 797 $ 941 Loss from operations $ — $ (1,979) $ (2,161) $ (2,002) Net loss $ — $ (3,935) $ (2,184) $ (4,284) Net loss per share attributable to common stockholders - basic and diluted $ — $ (0.28) $ (0.14) $ (0.25)

Summary of Significant Accoun32

Summary of Significant Accounting Policies (Schedule of Earnings Per Share) (Details) - USD ($)	3 Months Ended								9 Months Ended	12 Months Ended
	Dec. 31, 2017	Sep. 30, 2017	Jun. 30, 2017	Mar. 31, 2017	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2016	Dec. 31, 2017	Dec. 31, 2016
Net loss	$ (2,270,000)	$ (1,980,000)	$ (1,860,000)	$ (1,789,000)	$ (4,284,000)	$ (2,184,000)	$ (3,935,000)	$ 0	$ (10,403,036)	$ (7,899,001)	$ (13,113,220)
Preferred stock beneficial conversion charge									0	0
Undeclared cumulative preferred dividends									0	0	(75,460)
Net loss attributable to common stockholders									$ (10,403,036)	$ (7,899,001)	$ (13,188,680)
Weighted average common shares outstanding - basic and diluted									15,393,402	22,963,382	14,220,977
Basic and diluted net loss per share attributable to common stockholders	$ (0.09)	$ (0.08)	$ (0.08)	$ (0.1)	$ (0.25)	$ (0.14)	$ (0.28)	$ 0	$ (0.68)	$ (0.34)	$ (0.93)

Summary of Significant Accoun33

Summary of Significant Accounting Policies (Schedule of Antidilutive Shares) (Details) - shares	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	165,189	9,162,082
Stock Options [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	154,479	4,582,383
Warrants [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	10,710	4,579,699

Summary of Significant Accoun34

Summary of Significant Accounting Policies (Narrative) (Details) - USD ($)	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017
Significant Accounting Policies Additional Information [Line Items]
Allowance for doubtful accounts receivable	$ 75,000	$ 70,000
Maturity Period Of Highly Liquid Investments		90 days
Cash, FDIC Insured Amount		$ 250,000
Cash		$ 14,800,000
Cryogenic Shippers [Member]
Significant Accounting Policies Additional Information [Line Items]
Property Plant Equipment Ownership Percentage		47.00%
Data loggers [Member]
Significant Accounting Policies Additional Information [Line Items]
Property Plant Equipment Ownership Percentage	44.00%
Furniture and Fixtures [Member] | Minimum [Member]
Significant Accounting Policies Additional Information [Line Items]
Property, Plant and Equipment, Useful Life		3 years
Furniture and Fixtures [Member] | Maximum [Member]
Significant Accounting Policies Additional Information [Line Items]
Property, Plant and Equipment, Useful Life		7 years
Foreign Customers [Member]
Significant Accounting Policies Additional Information [Line Items]
Revenues	$ 750,400	$ 1,300,000
Accounts Receivable [Member]
Significant Accounting Policies Additional Information [Line Items]
Concentration risk, percentage		10.00%
Sales Revenue, Net [Member]
Significant Accounting Policies Additional Information [Line Items]
Concentration risk, percentage	10.00%	10.00%
Sales Revenue, Net [Member] | Customer One [Member]
Significant Accounting Policies Additional Information [Line Items]
Concentration risk, percentage	12.30%
Sales Revenue, Net [Member] | Foreign Customers [Member]
Significant Accounting Policies Additional Information [Line Items]
Concentration risk, percentage		11.00%

Inventories (Details)

Inventories (Details) - USD ($)	Dec. 31, 2017	Dec. 31, 2016
Raw materials	$ 104,745	$ 58,655
Finished goods	10,051	30,844
Inventory, Net	$ 114,796	$ 89,499

Property and Equipment (Details

Property and Equipment (Details) - USD ($)	Dec. 31, 2017	Dec. 31, 2016
Cryogenic shippers and data loggers	$ 2,107,642	$ 1,525,409
Furniture and fixtures	63,411	59,961
Computers and software	519,198	474,681
Machinery and equipment	362,476	310,398
Leasehold improvements	436,620	426,105
Fixed assets in process	568,688	106,598
Property, Plant and Equipment, Gross	4,058,035	2,903,152
Less accumulated depreciation and amortization	(1,546,861)	(1,256,048)
Property, Plant and Equipment, Net	$ 2,511,174	$ 1,647,104

Property and Equipment (Narrati

Property and Equipment (Narrative) (Details) - USD ($)	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017
Depreciation	$ 292,700	$ 664,800

Intangible Assets (Schedule of

Intangible Assets (Schedule of Intangible Assets) (Details) - USD ($)	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017
Gross Amount	$ 597,820	$ 683,466
Accumulated Amortization	(592,820)	(592,820)
Net Amount	5,000	90,646
Patents and trademarks [Member]
Gross Amount	52,375	138,021
Accumulated Amortization	(47,375)	(47,375)
Net Amount	$ 5,000	$ 90,646
Weighted Average Amortization Period (years)	0 years	0 years
Software development costs [Member]
Gross Amount	$ 545,445	$ 545,445
Accumulated Amortization	(545,445)	(545,445)
Net Amount	$ 0	$ 0
Weighted Average Amortization Period (years)	0 years	0 years

Intangible Assets (Narrative) (

Intangible Assets (Narrative) (Details) - USD ($)	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017
Amortization of Intangible Assets	$ 8,600	$ 0
Finite-Lived Intangible Assets, Amortization Expense, Next Twelve Months		$ 0

Accrued Compensation and Rela40

Accrued Compensation and Related Expenses (Details) - USD ($)	Dec. 31, 2017	Dec. 31, 2016
Accrued salaries and wages	$ 617,984	$ 166,008
Accrued paid time off	307,530	207,026
Accrued board of director fees	0	46,000
Employee-related Liabilities, Current	$ 925,514	$ 419,034

Related-Party Transactions (Nar

Related-Party Transactions (Narrative) (Details) - USD ($)	1 Months Ended	9 Months Ended	12 Months Ended
	Oct. 28, 2016	Dec. 31, 2016	Dec. 31, 2017	Mar. 31, 2016	Jan. 30, 2016
Aggregate principal balances		$ 646,700
Interest Payable		11,400	$ 0
Related-party interest expense		39,500	$ 9,600
Common stock exercise price	$ 4.50		$ 1.88		$ 3.57
Class of Warrant or Right, Number of Securities Called by Warrants or Rights			261,083
Class Of Warrant Or Rights Expiration Date	Oct. 28, 2019
Legal Fees			$ 5,000
Amended and Restated Notes [Member]
Amortization of Debt Discount (Premium)		18,700	$ 6,100
Debt Instrument, Payment Terms			The Amended and Restated Notes increased the interest rate to 7% per annum, extended the term to April 1, 2017, and modified the repayment provisions to provide for (i) repayment on March 1, 2016 of the outstanding amount of interest accrued through February 29, 2016, (ii) repayment of 10% of the original principal balance and accrued interest of such notes on a quarterly basis commencing April 1, 2016, and (iii) payment of the remaining outstanding balance on April 1, 2017.
Warrants Not Settleable in Cash, Fair Value Disclosure		$ 26,900
June 2015 [Member]
Debt Instrument, Periodic Payment, Principal			$ 72,000
Maximum [Member]
Debt Instrument, Periodic Payment, Principal			1,000
Notes Payable to Related Parties [Member]
Debt Instrument, Periodic Payment, Principal			$ 20,000
Patrick Mullins, M.D. [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights			11,910
Maryl Petreccia [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights			7,088
Jeffrey Dell, M.D. [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights			5,553
Raymond Takahashi, M.D [Member]
Aggregate principal balances				$ 35,800
Common stock exercise price			$ 6
Class of Warrant or Right, Number of Securities Called by Warrants or Rights			1,490
Class Of Warrant Or Rights Expiration Date			Feb. 19, 2018
Marc Grossman, M.D. [Member]
Aggregate principal balances				$ 6,500
Interest rate			6.00%

Commitments and Contingencies42

Commitments and Contingencies (Schedule of Future Minimum Lease Payments) (Details)	Dec. 31, 2017USD ($)
2,018	$ 405,609
2,019	416,370
2,020	428,868
2,021	441,736
2,022	454,984
Thereafter	274,405
Operating Leases, Future Minimum Payments Due, Total	$ 2,421,972

Commitments and Contingencies43

Commitments and Contingencies (Narrative) (Details)	1 Months Ended	9 Months Ended	12 Months Ended
	Sep. 16, 2015USD ($)	Dec. 31, 2016USD ($)	Dec. 31, 2017USD ($)ft²
Property Subject to or Available for Operating Lease [Line Items]
Rental expense		$ 222,700	$ 298,500
Consulting Service Fee		$ 252,600	179,100
KLATU Networks, LLC [Member] | Purchase and Sale Agreement [Member]
Property Subject to or Available for Operating Lease [Line Items]
Technology Services Costs	$ 400,000
Installment amount of Service costs	200,000
Minimum [Member] | KLATU Networks, LLC [Member]
Property Subject to or Available for Operating Lease [Line Items]
Technology Services Costs	$ 25,000
Irvine, California Facility [Member]
Property Subject to or Available for Operating Lease [Line Items]
Estimated Base Rent Under Lease			$ 24,700
Lease Expiration Date			Feb. 28, 2023
Land Subject to Ground Leases | ft²			27,600
Livingston [Member]
Property Subject to or Available for Operating Lease [Line Items]
Estimated Base Rent Under Lease			$ 7,600

Stockholders' Equity (Schedule

Stockholders' Equity (Schedule of Common Stock Reserved for Future Issuance) (Details)	Dec. 31, 2017shares
Class of Stock [Line Items]
Common Stock Reserved for Future Issuance	10,463,970
Exercise Of Stock Options [Member]
Class of Stock [Line Items]
Common Stock Reserved for Future Issuance	5,322,858
Exercise Of Warrants [Member]
Class of Stock [Line Items]
Common Stock Reserved for Future Issuance	5,141,112

Stockholders' Equity (Narrative

Stockholders' Equity (Narrative) (Details) - USD ($)	Apr. 07, 2016	Jul. 31, 2017	Mar. 31, 2017	Oct. 28, 2016	Jun. 20, 2016	Jan. 30, 2016	Dec. 31, 2016	Dec. 31, 2016	Dec. 31, 2017	Dec. 31, 2016	Jun. 27, 2017	Apr. 30, 2015	Feb. 28, 2015	May 31, 2014
Class of Stock [Line Items]
Common stock, shares authorized							50,000,000	50,000,000	50,000,000	50,000,000
Common stock, par value						$ 0.001	$ 0.001	$ 0.001	$ 0.001	$ 0.001
Preferred stock, par value							$ 0.001	$ 0.001	$ 0.001	$ 0.001
Preferred stock, shares authorized							2,500,000	2,500,000	2,500,000	2,500,000
Class Of Warrant Or Right, Number Of Securities Called By Warrants Or Rights									261,083
Class of Warrant or Right, Exercise Price of Warrants or Rights				$ 4.50		$ 3.57			$ 1.88
Preferred Stock Dividends, Income Statement Impact								$ 0	$ 0	$ 75,460
Stock Issued During Period, Shares, Issued for Services				2,470,913
Common Stock, Capital Shares Reserved For Future Issuance									10,463,970
Stock Issued During Period, Value, New Issues								989,898
Proceeds from Issuance of Common Stock				$ 3,700,000				0	$ 11,405,924	0
Stock Issued During Period, Shares, Conversion of Convertible Securities						4,977,038
Class Of Warrant Or Right Number Of Warrants Exercised	2,020,597			2,470,913		4,977,038
Proceeds from Warrant Exercises								0	5,151,660	0
Class Of Warrant Or Rights Expiration Date				Oct. 28, 2019
Fair Value Adjustment of Warrants								$ 4,195,252	$ 0	$ 4,195,252
Board Of Directors [Member]
Class of Stock [Line Items]
Stock Issued During Period, Shares, Issued for Services								19,587
Stock Issued During Period, Value, Issued for Services								$ 47,800
Director [Member]
Class of Stock [Line Items]
Stock Issued During Period, Shares, Issued for Services									15,872
Stock Issued During Period, Value, Issued for Services									$ 70,000
Original Warrants [Member]
Class of Stock [Line Items]
Class Of Warrant Or Right, Number Of Securities Called By Warrants Or Rights				5,000,000
Class of Warrant or Right, Exercise Price of Warrants or Rights				$ 3.57
New Warrants [Member]
Class of Stock [Line Items]
Class of Warrant or Right, Exercise Price of Warrants or Rights				$ 1.50
Supplemental Warrants [Member]
Class of Stock [Line Items]
Class Of Warrant Or Right, Number Of Securities Called By Warrants Or Rights				617,695
Class of Warrant or Right, Exercise Price of Warrants or Rights				$ 3
Proceeds from Warrant Exercises		$ 1,800,000
Class Of Warrant Or Rights Expiration Date		Jul. 27, 2017
Class Of Warrant Or Right Exercised Number		605,114
Class Of Warrant Or Right Exercisable Terms		The warrants were exercisable upon issuance and expired on the earlier of (i) October 28, 2019 and (ii) the thirtieth (30th) day after the date that the closing price of the Company’s common stock equals or exceeded $4.50 for ten consecutive trading days.
IPO [Member]
Class of Stock [Line Items]
Class of Warrant or Right, Exercise Price of Warrants or Rights						$ 3.57
Rights Offering [Member]
Class of Stock [Line Items]
Stock Issued During Period, Shares, New Issues					841,873
Proceeds from Issuance of Common Stock					$ 1,300,000
Deferred Finance Costs, Net					$ 315,000
Right Offering Price Per Share, Percentage of Weighted Average Price Per Share of Common Stock					85.00%
Share Price					$ 1.55
Tender Offer [Member]
Class of Stock [Line Items]
Class Of Warrant Or Right, Number Of Securities Called By Warrants Or Rights	2,448,000
Deferred Finance Costs, Net									281,500
Reduction Of Exercise Price	$ 1.25
Induced Conversion of Convertible Debt Expense								$ 1,929,800
Payments of Stock Issuance Costs									$ 477,300
Fair Value Adjustment of Warrants							$ 2,265,400
Tender Offer [Member] | Amended [Member]
Class of Stock [Line Items]
Class Of Warrant Or Right, Number Of Securities Called By Warrants Or Rights	2,020,597
Proceeds from Warrant Exercises	$ 2,500,000
Tender Offer [Member] | New Warrants [Member]
Class of Stock [Line Items]
Class Of Warrant Or Right Fair Value Of Warrant issued							1,649,600
Tender Offer [Member] | Supplemental Warrants [Member]
Class of Stock [Line Items]
Class Of Warrant Or Right Fair Value Of Warrant issued							$ 615,900
Underwritten Public Offering [Member]
Class of Stock [Line Items]
Stock Issued During Period, Shares, New Issues			6,325,000
Stock Issued During Period, Value, New Issues			$ 12,700,000
Proceeds from Issuance of Common Stock			$ 11,400,000
Shares Issued, Price Per Share			$ 2
Over-Allotment Option [Member]
Class of Stock [Line Items]
Stock Issued During Period, Value, Issued for Services			$ 825,000
Public Offering [Member]
Class of Stock [Line Items]
Payments of Stock Issuance Costs			$ 170,300
Minimum [Member]
Class of Stock [Line Items]
Share Price											$ 4.50
Class A convertible preferred stock [Member]
Class of Stock [Line Items]
Preferred stock, par value							$ 0.001	$ 0.001	$ 0.001	$ 0.001
Preferred stock, shares authorized							800,000	800,000	800,000	800,000				800,000
Preferred Stock, Shares Outstanding						454,750	0	0	0	0
Class B Convertible Preferred Stock [Member]
Class of Stock [Line Items]
Preferred stock, shares authorized													400,000
Preferred Stock, Shares Outstanding						534,571
Class B Convertible Preferred Stock [Member] | Maximum [Member]
Class of Stock [Line Items]
Preferred stock, shares authorized												585,000
Class B Convertible Preferred Stock [Member] | Minimum [Member]
Class of Stock [Line Items]
Preferred stock, shares authorized												400,000

Stock-Based Compensation (Summa

Stock-Based Compensation (Summary of Warrant Activity) (Details) - Warrants [Member] - USD ($)		9 Months Ended	12 Months Ended
		Dec. 31, 2016	Dec. 31, 2017
Number of Shares
Outstanding		11,153,868	7,447,478
Issued		795,927	0
Exercised		(4,491,510)	(1,664,232)
Expired		(10,807)	(642,134)
Outstanding		7,447,478	5,141,112
Vested (exercisable)			5,141,112
Weighted-Average Exercise Price/Share
Outstanding		$ 3.3	$ 4.29
Issued		2.79	0
Exercised		1.39	3.25
Expired		82.12	8.55
Outstanding		$ 4.29	4.09
Vested (exercisable)			$ 4.09
Weighted-Average Remaining Contractual Term (Years)
Outstanding			2 years 3 months 18 days
Vested (exercisable)			2 years 3 months 18 days
Aggregated Intrinsic Value
Outstanding	[1]		$ 24,108,800
Vested (exercisable)	[1]		$ 24,108,800
[1]	Aggregate intrinsic value represents the difference between the exercise price of the warrant and the closing market price of the Company’s common stock on December 31, 2017, which was $8.59 per share.

Stock-Based Compensation (Sched

Stock-Based Compensation (Schedule of Assumptions Used to Estimate Fair Value of Stock Options) (Details)	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016
Warrants [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected life (years)	0 years
Risk-free interest rate	0.00%
Risk-free interest rate, minimum		0.93%
Risk-free interest rate, maximum		1.14%
Volatility	0.00%
Volatility, minimum		103.00%
Volatility, maximum		116.00%
Dividend yield	0.00%	0.00%
Warrants [Member] | Minimum [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected life (years)		2 years 4 months 24 days
Warrants [Member] | Maximum [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected life (years)		5 years
Stock Options [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Risk-free interest rate, minimum	1.79%	1.17%
Risk-free interest rate, maximum	2.23%	2.09%
Volatility, minimum	111.00%	113.00%
Volatility, maximum	115.00%	118.00%
Dividend yield	0.00%	0.00%
Stock Options [Member] | Minimum [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected life (years)	5 years 3 months 18 days	6 years
Stock Options [Member] | Maximum [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected life (years)	6 years 7 months 6 days	6 years 1 month 6 days

Stock-Based Compensation (Sch48

Stock-Based Compensation (Schedule of Warrants Outstanding and Exercisable) (Details) - Warrants [Member]	12 Months Ended
	Dec. 31, 2017$ / sharesshares
Number Outstanding	5,141,112
Number Exercisable	5,141,112
$1.88 - 2.40 [Member]
Number Outstanding	146,206
Weighted-Average Remaining Contractual Life (Years)	1 year 10 months 24 days
Weighted-Average Exercise Price | $ / shares	$ 2.17
Number Exercisable	146,206
Weighted-Average Exercise Price | $ / shares	$ 2.17
$3.00 - 3.57 [Member]
Number Outstanding	3,836,793
Weighted-Average Remaining Contractual Life (Years)	2 years 7 months 6 days
Weighted-Average Exercise Price | $ / shares	$ 3.57
Number Exercisable	3,836,793
Weighted-Average Exercise Price | $ / shares	$ 3.57
$4.44 - 4.47 [Member]
Number Outstanding	599,898
Weighted-Average Remaining Contractual Life (Years)	9 months 18 days
Weighted-Average Exercise Price | $ / shares	$ 4.44
Number Exercisable	599,898
Weighted-Average Exercise Price | $ / shares	$ 4.44
$5.88 - 6.00 [Member]
Number Outstanding	547,323
Weighted-Average Remaining Contractual Life (Years)	1 year 10 months 24 days
Weighted-Average Exercise Price | $ / shares	$ 6
Number Exercisable	547,323
Weighted-Average Exercise Price | $ / shares	$ 6
$61.20 - 129.60
Number Outstanding	10,892
Weighted-Average Remaining Contractual Life (Years)	8 months 12 days
Weighted-Average Exercise Price | $ / shares	$ 99.97
Number Exercisable	10,892
Weighted-Average Exercise Price | $ / shares	$ 99.97

Stock-Based Compensation (Detai

Stock-Based Compensation (Details) - USD ($)	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017	Dec. 31, 2016
Share-based Compensation	$ 2,329,003	$ 3,547,781	$ 3,117,946
Cost of Revenues [Member]
Share-based Compensation	18,355	43,349
General and Administrative Expense [Member]
Share-based Compensation	1,791,981	2,689,496
Selling and Marketing Expense [Member]
Share-based Compensation	510,078	723,648
Engineering And Development [Member]
Share-based Compensation	$ 8,589	$ 91,288

Stock-Based Compensation (Sum50

Stock-Based Compensation (Summary of Stock Option Activity) (Details) - Stock Options [Member] - USD ($)		9 Months Ended	12 Months Ended
		Dec. 31, 2016	Dec. 31, 2017
Number of Shares
Outstanding		3,999,325	4,512,550
Issued		892,774	1,176,300
Exercised		0	(209,456)
Forfeited		(294,799)	(101,199)
Expired		(84,750)	(55,357)
Outstanding		4,512,550	5,322,858
Vested (exercisable)			2,871,876
Expected to vest after (unexercisable)			2,450,982
Weighted-Average Exercise Price/Share
Outstanding		$ 4.44	$ 4.01
Granted		1.89	4.59
Exercised		0	3.09
Forfeited		3.28	3.04
Expired		4.61	7.89
Outstanding		$ 4.01	4.16
Vested (exercisable)			4.16
Expected to vest after (unexercisable)			$ 4.16
Weighted-Average Remaining Contractual Term (Years)
Outstanding			7 years 8 months 12 days
Vested (exercisable)			7 years 1 month 6 days
Expected to vest after (unexercisable)			8 years 4 months 24 days
Aggregated Intrinsic Value
Outstanding	[1]		$ 23,718,000
Vested (exercisable)	[1]		12,751,500
Expected to vest after (unexercisable)	[1]		$ 10,966,500
[1]	Aggregate intrinsic value represents the difference between the exercise price of the option and the closing market price of the common stock on December 31, 2017, which was $8.59 per share.

Stock-Based Compensation (Sch51

Stock-Based Compensation (Schedule of Stock Options Outstanding and Exercisable) (Details) - Stock Options [Member]	12 Months Ended
	Dec. 31, 2017$ / sharesshares
Number Outstanding	5,322,858
Number Exercisable	2,871,876
$1.08 - 2.66 [Member]
Number Outstanding	920,102
Weighted-Average Remaining Contractual Life (Years)	7 years 10 months 24 days
Weighted-Average Exercise Price | $ / shares	$ 1.88
Number Exercisable	430,510
Weighted-Average Exercise Price | $ / shares	$ 1.98
$3.00 - 3.96 [Member]
Number Outstanding	1,976,705
Weighted-Average Remaining Contractual Life (Years)	7 years 9 months 18 days
Weighted-Average Exercise Price | $ / shares	$ 3.2
Number Exercisable	1,020,669
Weighted-Average Exercise Price | $ / shares	$ 3.17
$4.80 - 4.92 [Member]
Number Outstanding	835,628
Weighted-Average Remaining Contractual Life (Years)	7 years 3 months 18 days
Weighted-Average Exercise Price | $ / shares	$ 4.77
Number Exercisable	587,815
Weighted-Average Exercise Price | $ / shares	$ 4.77
$5.00 - 6.65 [Member]
Number Outstanding	956,471
Weighted-Average Remaining Contractual Life (Years)	7 years 7 months 6 days
Weighted-Average Exercise Price | $ / shares	$ 5.09
Number Exercisable	541,682
Weighted-Average Exercise Price | $ / shares	$ 5.06
$7.80 - 7.89 [Member]
Number Outstanding	442,451
Weighted-Average Remaining Contractual Life (Years)	7 years 4 months 24 days
Weighted-Average Exercise Price | $ / shares	$ 7.8
Number Exercisable	278,699
Weighted-Average Exercise Price | $ / shares	$ 7.8
$8.20 - 22.68 [Member]
Number Outstanding	191,501
Weighted-Average Remaining Contractual Life (Years)	9 years 4 months 24 days
Weighted-Average Exercise Price | $ / shares	$ 9.34
Number Exercisable	12,501
Weighted-Average Exercise Price | $ / shares	$ 12.02

Stock-Based Compensation (Narra

Stock-Based Compensation (Narrative) (Details) - USD ($)	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017	Dec. 31, 2016	Oct. 31, 2015
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value		$ 797,600
Warrants Exercised Intrinsic Value	$ 3,200,000	$ 7,100,000
Stock Issued During Period Shares Cashless Exercise Of Warrants		144,164
Class Of Warrant Or Right, Number Of Securities Called By Warrants Or Rights		261,083
Proceeds from Warrant Exercises	$ 0	$ 5,151,660	$ 0
Warrants [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Intrinsic value per share		$ 8.59
Class Of Warrant Or Right, Number Of Securities Called By Warrants Or Rights		1,403,149
Proceeds from Warrant Exercises		$ 4,500,000
Stock Options [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Unrecognized compensation cost related to unvested stock options		$ 7,400,000
Weighted average recognition period		2 years 4 months 24 days
Plan 2015 [Member] | Stock Options [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total shares available for future grant		1,339,909		5,000,000

Income Taxes (Schedule of Defer

Income Taxes (Schedule of Deferred Tax Assets) (Details) - USD ($) $ in Thousands	Dec. 31, 2017	Dec. 31, 2016
Deferred tax assets:
Net operating loss carryforward	$ 15,307	$ 20,668
Research credits	100	56
Expenses recognized for granting of options and warrants	2,014	2,316
Accrued expenses and reserves	41	43
Valuation allowance	(17,462)	(23,083)
Deferred Tax Assets, Net of Valuation Allowance	$ 0	$ 0

Income Taxes (Schedule of Incom

Income Taxes (Schedule of Income Tax Provision) (Details) - USD ($)	9 Months Ended	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2017	Dec. 31, 2016
Computed tax benefit at federal statutory rate		$ (2,684,000)	$ (3,535,000)
State tax, net of federal benefit		(277,000)	(196,000)
Stock compensation		503,000	607,000
Warrant inducement and repricing costs		0	1,426,000
Permanent items and other		56,000	41,000
Tax Cuts and Jobs Act		8,032,000	0
Valuation allowance		(5,625,000)	1,663,000
Income Tax Expense (Benefit)	$ 5,673	$ 5,143	$ 5,673

Income Taxes (Schedule of unrec

Income Taxes (Schedule of unrecognized tax positions) (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016
Domestic Tax Authority [Member]
Unrecognized tax positions, beginning of period	$ 0	$ 0
Gross increase - current period tax positions	7	0
Gross decrease - prior period tax positions	0	0
Gross increase - prior period tax positions	6	0
Expiration of statute of limitations	0	0
Unrecognized tax positions, end of period	13	0
State and Local Jurisdiction [Member]
Unrecognized tax positions, beginning of period	0	0
Gross increase - current period tax positions	7	0
Gross decrease - prior period tax positions	0	0
Gross increase - prior period tax positions	4	0
Expiration of statute of limitations	0	0
Unrecognized tax positions, end of period	$ 11	$ 0

Income Taxes (Narrative) (Detai

Income Taxes (Narrative) (Details) - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Operating Loss Carryforwards [Line Items]
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent		35.00%
Increase (Decrease) in Deferred Income Taxes		$ 8,000,000
Scenario, Plan [Member]
Operating Loss Carryforwards [Line Items]
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent	21.00%
Domestic Tax Authority [Member]
Operating Loss Carryforwards [Line Items]
Operating Loss Carryforwards		58,490,000
Tax Credit Carryforward, Amount		53,000
State and Local Jurisdiction [Member]
Operating Loss Carryforwards [Line Items]
Operating Loss Carryforwards		46,573,000
Tax Credit Carryforward, Amount		$ 45,000

Quarterly Financial Data (Detai

Quarterly Financial Data (Details) - USD ($)	3 Months Ended								9 Months Ended	12 Months Ended
	Dec. 31, 2017	Sep. 30, 2017	Jun. 30, 2017	Mar. 31, 2017	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2016	Dec. 31, 2017	Dec. 31, 2016
Total revenues	$ 3,322,000	$ 3,003,000	$ 2,917,000	$ 2,712,000	$ 2,229,000	$ 1,977,000	$ 1,918,000	$ 0	$ 6,123,271	$ 11,954,267	$ 7,678,816
Gross margin	1,713,000	1,606,000	1,393,000	1,253,000	941,000	797,000	782,000	0	2,519,616	5,966,433	3,101,423
Loss from operations	(2,271,000)	(1,988,000)	(1,864,000)	(1,769,000)	(2,002,000)	(2,161,000)	(1,979,000)	0	(6,141,991)	(7,892,502)	(8,766,109)
Net loss	$ (2,270,000)	$ (1,980,000)	$ (1,860,000)	$ (1,789,000)	$ (4,284,000)	$ (2,184,000)	$ (3,935,000)	$ 0	$ (10,403,036)	$ (7,899,001)	$ (13,113,220)
Net loss per share attributable to common stockholders - basic and diluted	$ (0.09)	$ (0.08)	$ (0.08)	$ (0.1)	$ (0.25)	$ (0.14)	$ (0.28)	$ 0	$ (0.68)	$ (0.34)	$ (0.93)

Subsequent Event (Narrative) (D

Subsequent Event (Narrative) (Details) - USD ($)	1 Months Ended			3 Months Ended	9 Months Ended	12 Months Ended
	Feb. 28, 2018	Jan. 31, 2016	Jul. 31, 2015	Mar. 31, 2018	Dec. 31, 2016	Dec. 31, 2017	Dec. 31, 2016	Feb. 08, 2018	Jan. 02, 2018	Oct. 28, 2016	Jan. 30, 2016
Subsequent Event [Line Items]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights						261,083
Class of Warrant or Right, Exercise Price of Warrants or Rights						$ 1.88				$ 4.50	$ 3.57
Fair Value Adjustment of Warrants					$ 4,195,252	$ 0	$ 4,195,252
Original Warrants [Member]
Subsequent Event [Line Items]
Number Of Units Issued		4,977,038	2,090,750
Subsequent Event [Member]
Subsequent Event [Line Items]
Stock Issued During Period, Shares, New Issues	4,700,000
Class of Warrant or Right, Number of Securities Called by Warrants or Rights								1,580,388
Fair Value Adjustment of Warrants	$ 899,400
Payments of Stock Issuance Costs				$ 99,400
Subsequent Event [Member] | Original Warrants [Member]
Subsequent Event [Line Items]
Class of Warrant or Right, Exercise Price of Warrants or Rights								$ 3.57
Class of Warrant or Right, Outstanding									3,836,793
Subsequent Event [Member] | New Warrants [Member]
Subsequent Event [Line Items]
Class of Warrant or Right, Exercise Price of Warrants or Rights								$ 3