CIBC World Markets Corp. | Piper Jaffray & Co. | |
300 Madison Avenue | U.S. Bancorp Center | |
New York, New York 10017 | 800 Nicollet Mall | |
Minneapolis, Minnesota 55402 |
January 20, 2006
VIA FACSIMILE AND EDGAR TRANSMISSION
Securities and Exchange Commission | ||
Division of Corporation Finance | ||
100 F. Street, N.E. | ||
Washington, D.C. 20549 | ||
Attention: | Jeffrey P. Reidler, Esq. | |
Mary K. Fraser, Esq. |
Re: | SGX Pharmaceuticals, Inc. (the “Company”) | |||
Registration Statement on Form S-1 (File No. 333-128059) |
Ladies and Gentlemen:
In accordance with Rule 461 of the General Rules and Regulations under the Securities Act of 1933, as amended (the “Act”), as representatives of the several underwriters, in connection with the above-referenced issue, we hereby join in the request of the Company that the effectiveness of the above-captioned Registration Statement, as amended, be accelerated to 4:30 p.m. E.S.T. on January 24, 2006, or as soon thereafter as practicable.
In connection with Rule 460 of the Act, please be advised that we have effected approximately the following distribution of copies of the Preliminary Prospectus dated January 4, 2006 through the date hereof:
6,500 copies to prospective Underwriters, institutional investors, dealers and others.
The undersigned has and will, and each participating underwriter and dealer has advised the undersigned that it has and will, comply with the provisions of Rule 15c2-8 of the Securities Exchange Act of 1934, as amended, in connection with the above-referenced issue.
Very truly yours, | ||
CIBC WORLD MARKETS CORP. | ||
PIPER JAFFRAY & CO. | ||
JMP SECURITIES LLC | ||
As Representatives of the several underwriters |
By: CIBC WORLD MARKETS CORP. | By: PIPER JAFFRAY & CO. | |||||||||
By: | /s/ Jose L. Zardoya | By: | /s/ Scott A. Beardsley | |||||||
Title: Executive Director | Title: Managing Director |