Cyclacel Pharmaceuticals (CYCC) 10-Q 13 Aug 19 2019 Q2 Quarterly report Financial data

Document and Entity Information

Document and Entity Information - shares	6 Months Ended
	Jun. 30, 2019	Aug. 09, 2019
Document and Entity Information [Abstract]
Entity Registrant Name	Cyclacel Pharmaceuticals, Inc.
Entity Central Index Key	0001130166
Trading Symbol	cycc
Current Fiscal Year End Date	--12-31
Entity Filer Category	Non-accelerated Filer
Entity Common Stock, Shares Outstanding		17,199,974
Document Type	10-Q
Document Period End Date	Jun. 30, 2019
Amendment Flag	false
Document Fiscal Year Focus	2019
Document Fiscal Period Focus	Q2
Entity Small Business	true
Entity Emerging Growth Company	false
Entity Current Reporting Status	Yes

CONSOLIDATED BALANCE SHEETS

CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
Current assets:
Cash and cash equivalents	$ 15,159	$ 17,504
Prepaid expenses and other current assets	2,991	2,283
Total current assets	18,150	19,787
Property and equipment, net	29	36
Right-of-use lease asset	1,285
Total assets	19,464	19,823
Current liabilities:
Accounts payable	1,106	2,719
Accrued and other current liabilities	1,394	1,732
Total current liabilities	2,500	4,451
Lease liability	1,233
Other liabilities		100
Total liabilities	3,733	4,551
Stockholders' equity:
Preferred stock, value
Common stock, $0.001 par value; 100,000,000 shares authorized at December 31, 2018 and June 30, 2019; 12,497,447 and 17,199,974 shares issued and outstanding at December 31, 2018 and June 30, 2019.	(17)	(12)
Additional paid-in capital	369,944	365,817
Accumulated other comprehensive loss	(808)	(760)
Accumulated deficit	(353,422)	(349,797)
Total stockholders' equity	15,731	15,272
Total liabilities and stockholders' equity	19,464	19,823
Convertible Exchangeable Preferred Stock
Stockholders' equity:
Preferred stock, value
Series A convertible preferred stock
Stockholders' equity:
Preferred stock, value

CONSOLIDATED BALANCE SHEETS (Pa

CONSOLIDATED BALANCE SHEETS (Parentheticals) - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
Preferred stock, par value (in dollars per share)	$ 0.001	$ 0.001
Preferred stock, shares authorized	5,000,000	5,000,000
Preferred stock, liquidation preference value (in dollars)	$ 4,006,512	$ 4,006,512
Common stock, par value (in dollars per share)	$ 0.001	$ 0.001
Common stock, shares authorized	100,000,000	100,000,000
Common stock, shares issued	17,199,974	12,497,447
Common stock, shares outstanding	17,199,974	12,497,447
6% Convertible Exchangeable Preferred Stock
Preferred stock, shares issued	335,273	335,273
Preferred stock, shares outstanding	335,273	335,273
Series A convertible preferred stock
Preferred stock, par value (in dollars per share)	$ 0.001	$ 0.001
Preferred stock, shares issued	264	264
Preferred stock, shares outstanding	264	264

CONSOLIDATED STATEMENTS OF OPER

CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Revenues:
Total revenues	$ 0	$ 0	$ 0	$ 0
Operating expenses:
Research and development	1,153	1,182	2,165	1,980
General and administrative	1,184	1,283	2,376	2,647
Total operating expenses	2,337	2,465	4,541	4,627
Operating loss	(2,337)	(2,465)	(4,541)	(4,627)
Other income (expense):
Foreign exchange gains (losses)	21	(39)	36	(43)
Interest income	56	84	135	153
Other income, net	170	66	170	632
Total other income (expense), net	247	111	341	742
Loss before taxes	(2,090)	(2,354)	(4,200)	(3,885)
Income tax benefit	307	502	575	684
Net loss	(1,783)	(1,852)	(3,625)	(3,201)
Dividend on convertible exchangeable preferred shares	(50)	(50)	(101)	(101)
Net loss applicable to common shareholders	$ (1,833)	$ (1,902)	$ (3,726)	$ (3,302)
Basic and diluted earnings per common share:
Net loss per share - basic and diluted (in dollars per share)	$ (0.11)	$ (0.16)	$ (0.24)	$ (0.28)
Weighted average common shares outstanding (in shares)	17,199,974	11,997,447	15,428,962	11,997,447

CONSOLIDATED STATEMENTS OF COMP

CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS (Unaudited) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS
Net loss	$ (1,783)	$ (1,852)	$ (3,625)	$ (3,201)
Translation adjustment	4,453	9,624	556	3,296
Unrealized foreign exchange gain on intercompany loans	(4,480)	(9,577)	(603)	(3,301)
Comprehensive loss	$ (1,810)	$ (1,805)	$ (3,672)	$ (3,206)

CONSOLIDATED STATEMENTS OF STOC

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Preferred Stock	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Loss	Accumulated Deficit	Total
Balance at Dec. 31, 2017		$ 12	$ 365,057	$ (794)	$ (342,509)	$ 21,766
Balance (in shares) at Dec. 31, 2017	335,537	11,997,447
Increase (Decrease) in Stockholders' Equity
Issue of common stock on At Market Issuance sales agreement	$ 0	$ 0				0
Issue of common stock on At Market Issuance sales agreement (in shares)	0	0
Stock-based compensation			79			79
Preferred stock dividends			(50)			(50)
Unrealized foreign exchange on intercompany loans				6,276		6,276
Translation adjustment				(6,328)		(6,328)
Loss for the period					(1,348)	(1,348)
Balance at Mar. 31, 2018		$ 12	365,086	(846)	(343,857)	20,395
Balance (in shares) at Mar. 31, 2018	335,537	11,997,447
Balance at Dec. 31, 2017		$ 12	365,057	(794)	(342,509)	21,766
Balance (in shares) at Dec. 31, 2017	335,537	11,997,447
Increase (Decrease) in Stockholders' Equity
Unrealized foreign exchange on intercompany loans						(3,301)
Translation adjustment						3,296
Loss for the period						(3,201)
Balance at Jun. 30, 2018		$ 12	365,123	(801)	(345,710)	18,624
Balance (in shares) at Jun. 30, 2018	335,537	11,997,447
Balance at Mar. 31, 2018		$ 12	365,086	(846)	(343,857)	20,395
Balance (in shares) at Mar. 31, 2018	335,537	11,997,447
Increase (Decrease) in Stockholders' Equity
Issue of common stock on At Market Issuance sales agreement	$ 0	$ 0				0
Issue of common stock on At Market Issuance sales agreement (in shares)	0	0
Stock-based compensation			87			87
Preferred stock dividends			(50)			(50)
Unrealized foreign exchange on intercompany loans				(9,578)		(9,577)
Translation adjustment				9,623		9,624
Loss for the period					(1,853)	(1,852)
Balance at Jun. 30, 2018		$ 12	365,123	(801)	(345,710)	18,624
Balance (in shares) at Jun. 30, 2018	335,537	11,997,447
Balance at Dec. 31, 2018		$ 12	365,817	(760)	(349,797)	15,272
Balance (in shares) at Dec. 31, 2018	335,537	12,497,447
Increase (Decrease) in Stockholders' Equity
Issue of common stock on At Market Issuance sales agreement		$ 5	4,106			4,111
Issue of common stock on At Market Issuance sales agreement (in shares)		4,702,527
Stock-based compensation			85			85
Preferred stock dividends			(50)			(50)
Unrealized foreign exchange on intercompany loans				3,876		3,876
Translation adjustment				(3,897)		(3,897)
Loss for the period					(1,842)	(1,842)
Balance at Mar. 31, 2019		$ 17	369,958	(781)	(351,639)	17,555
Balance (in shares) at Mar. 31, 2019	335,537	17,199,974
Balance at Dec. 31, 2018		$ 12	365,817	(760)	(349,797)	15,272
Balance (in shares) at Dec. 31, 2018	335,537	12,497,447
Increase (Decrease) in Stockholders' Equity
Unrealized foreign exchange on intercompany loans						(603)
Translation adjustment						556
Loss for the period						(3,625)
Balance at Jun. 30, 2019		$ 17	369,944	(808)	(353,422)	15,731
Balance (in shares) at Jun. 30, 2019	335,537	17,199,974
Balance at Mar. 31, 2019		$ 17	369,958	(781)	(351,639)	17,555
Balance (in shares) at Mar. 31, 2019	335,537	17,199,974
Increase (Decrease) in Stockholders' Equity
Issue of common stock on At Market Issuance sales agreement			56			56
Stock-based compensation			92			92
Preferred stock dividends			(50)			(50)
Unrealized foreign exchange on intercompany loans				(4,480)		(4,480)
Translation adjustment				4,453		4,453
Loss for the period					(1,783)	(1,783)
Balance at Jun. 30, 2019		$ 17	$ 369,944	$ (808)	$ (353,422)	$ 15,731
Balance (in shares) at Jun. 30, 2019	335,537	17,199,974

CONSOLIDATED STATEMENTS OF CASH

CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018
Operating activities:
Net loss	$ (3,625)	$ (3,201)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	10	15
Gain on disposal of property and equipment	(29)
Stock-based compensation	178	167
Changes in lease liability	(52)
Changes in operating assets and liabilities:
Prepaid expenses and other assets	(749)	(860)
Accounts payable and other current liabilities	(2,052)	(63)
Net cash used in operating activities	(6,319)	(3,942)
Investing activities:
Purchase of property, plant and equipment	(3)	(31)
Proceeds from sale of property and equipment	29
Net cash provided by (used in) investing activities	26	(31)
Financing activities:
Proceeds from issuance of common stock, net of issuance costs	4,056
Payment of preferred stock dividend	(101)	(101)
Net cash provided by (used in) financing activities	3,955	(101)
Effect of exchange rate changes on cash and cash equivalents	(7)	(12)
Net (decrease) in cash and cash equivalents	(2,345)	(4,086)
Cash and cash equivalents, beginning of period	17,504	23,910
Cash and cash equivalents, end of period	15,159	19,824
Cash received during the period for:
Interest	135	153
Taxes	0	0
Non cash financing activities:
Accrual of preferred stock dividends	$ 50	$ 50

Company Overview

Company Overview	6 Months Ended
	Jun. 30, 2019
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Company Overview	1. Company Overview Nature of Operations Cyclacel Pharmaceuticals, Inc. (“Cyclacel” or “the Company”) is a clinical-stage using cell cycle control, transcriptional regulation and DNA damage response biology to develop innovative, targeted medicines for cancer and other proliferative diseases. Cyclacel is a pioneer company in the field of cell cycle biology with a vision to improve patient healthcare by translating cancer biology into medicines. As of June 30, 2019, substantially all efforts of the Company to date have been devoted to performing research and development, conducting clinical trials, developing and acquiring intellectual property, raising capital and recruiting and training personnel.

Summary of Significant Accounti

Summary of Significant Accounting Policies	6 Months Ended
	Jun. 30, 2019
Accounting Policies [Abstract]
Summary of Significant Accounting Policies	2. Summary of Significant Accounting Policies Basis of Presentation The consolidated balance sheet as of June 30, 2019, the consolidated statements of operations, comprehensive loss, and stockholders’ equity for the three and six months ended June 30, 2019 and 2018 and the consolidated statements of cash flows for the six months ended June 30, 2019 and 2018, and all related disclosures contained in the accompanying notes, are unaudited. The consolidated balance sheet as of December 31, 2018 is derived from the audited consolidated financial statements included in the Annual Report on Form 10-K for the fiscal year ended December 31, 2018 filed with the Securities and Exchange Commission (“SEC”). The consolidated financial statements are presented on the basis of accounting principles that are generally accepted in the United States (“GAAP”) for interim financial information and in accordance with the rules and regulations of the SEC. Accordingly, they do not include all the information and footnotes required by accounting principles generally accepted in the United States for a complete set of financial statements. In the opinion of management, all adjustments, which include only normal recurring adjustments necessary to present fairly the consolidated balance sheet as of June 30, 2019, and the results of operations and, comprehensive loss for the three and six months ended June 30, 2019, and cash flows for the six months ended June 30, 2019 have been made. The interim results for the three and six months ended June 30, 2019 are not necessarily indicative of the results to be expected for the year ending December 31, 2019 or for any other year. The consolidated financial statements should be read in conjunction with the audited consolidated financial statements and the accompanying notes for the year ended December 31, 2018 that are included in the Company’s Annual Report on Form 10-K filed with the SEC. Going Concern Management considers that there are no conditions or events, in the aggregate, that raise substantial doubt about the entity’s ability to continue as a going concern for a period of at least one year from the date the financial statements are issued. The Company expects that its cash of $15.2 million as of June 30, 2019 will be sufficient to fund its operating expenses and capital expenditure requirements through the end of 2020. This evaluation is based on relevant conditions and events that are known and reasonably knowable at the date that the financial statements are issued, including: a. The Company’s current financial condition, including its sources of liquidity; b. The Company’s conditional and unconditional obligations due or anticipated within one year; c. The funds necessary to maintain the Company’s operations considering its current financial condition, obligations, and other expected cash flows; and d. Other conditions and events, when considered in conjunction with the above, that may adversely affect the Company’s ability to meet its obligations. The future viability of the Company beyond the end of 2020 is dependent on its ability to raise additional capital to finance its operations. Accounting standards adopted in the period On January 1, 2019, the Company adopted the guidance on accounting for leases (“ASC 842”) in Accounting Standards Update No, 2016-02, Leases, The Company has elected the package of practical expedients permitted in ASC 842. Accordingly, the Company accounted for its existing operating leases as operating leases under the new guidance, without reassessing (a) whether the contracts contain a lease under ASC 842, (b) whether classification of the operating leases would be different in accordance with ASC 842, or (c) whether any unamortized initial direct costs would have met the definition of initial direct costs in ASC 842 at lease commencement. In addition, the Company has elected an accounting policy to not allocate payments made under the lease agreement between lease and non-lease components. The Company transitioned to the new guidance at the adoption date by recognizing a lease liability of $1.5 million for the present value of the remaining minimum rental payments, as defined under prior accounting rules, and a corresponding right-of-use asset. In addition, the Company reclassified an existing deferred rent obligation of $120,000 created under prior accounting rules against the opening right-of-use asset. Because the Company adopted the new leasing guidance on a cumulative catch-up basis effective January 1, 2019, the Company has not recast prior period financial statements for the effects of this new standard. Accordingly, the Company’s financial condition as of December 31, 2018 and June 30, 2019 may not be comparable. Recently Issued Accounting Pronouncements In August 2018, the FASB issued ASU 2018-15, "Customer's Accounting for Implementation Costs Incurred in a Cloud Computing Arrangement that is a Service Contract." ASU 2018-15 requires implementation costs incurred by customers in cloud computing arrangements to be deferred over the non-cancellable term of the cloud computing arrangements plus any optional renewal periods (1) that are reasonably certain to be exercised by the customer or (2) for which exercise of the renewal option is controlled by the cloud service provider. The effective date of this pronouncement is for fiscal years beginning after December 15, 2019, and interim periods within those fiscal years, and early adoption is permitted. The standard can be adopted either using the prospective or retrospective transition approach. The Company is currently evaluating the impact of this pronouncement on the Company's consolidated financial statements and disclosures. Fair Value of Financial Instruments Financial instruments consist of cash equivalents, accounts payable and accrued liabilities. The carrying amounts of cash equivalents, accounts payable and accrued liabilities approximate their respective fair values due to the nature of the accounts, notably their short maturities. Comprehensive Income (Loss) All components of comprehensive income (loss), including net income (loss), are reported in the financial statements in the period in which they are recognized. Comprehensive income (loss) is defined as the change in equity during a period from transactions and other events and circumstances from non-owner sources. Net income (loss) and other comprehensive income (loss), including foreign currency translation adjustments, are reported, net of any related tax effect, to arrive at comprehensive income (loss). No taxes were recorded on items of other comprehensive income (loss). There were no reclassifications out of other comprehensive income (loss) during the three months and six months ended June 30, 2018 and 2019. Revenue recognition With effect from January 1, 2018, the Company recognizes revenue using the five step-model provided in ASC 606, Revenue from Contracts with Customers (1) identify the contract with a customer; (2) identify the performance obligations in the contract; (3) determine the transaction price; (4) allocate the transaction price to the performance obligations in the contract; and (5) recognize revenue when, or as, the Company satisfies a performance obligation. The transaction price includes fixed payments and an estimate of variable consideration, including milestone payments. · Whether achievement of a development milestone is highly susceptible to factors outside the entity’s influence, such as milestones involving the judgment or actions of third parties, including regulatory bodies; · Whether the uncertainty about the achievement of the milestone is not expected to be resolved for a long period of time; · Whether the Company can reasonably predict that a milestone will be achieved based on previous experience; and. · The complexity and inherent uncertainty underlying the achievement of the milestone. The transaction price is allocated to each performance obligation based on the relative selling price of each performance obligation. The best estimate of the selling price is determined after considering all reasonably available information, including market data and conditions, entity-specific factors such as the cost structure of the deliverable and internal profit and pricing objectives. The revenue allocated to each performance obligation is recognized as or when the Company satisfies the performance obligation. The Company recognizes a contract asset, when the value of satisfied (or part satisfied) performance obligations is in excess of the payment due to the Company, and deferred revenue when the amount of unconditional consideration is in excess of the value of satisfied (or part satisfied) performance obligations. Once a right to receive consideration is unconditional, that amount is presented as a receivable. With effect from January 1, 2018, grant revenue, if new grants are obtained, will be presented as a reduction against the related research and development expenses. Leases Effective from January 1, 2019, the Company accounts for lease contracts in accordance with ASC 842. As of June 30, 2019, all of the Company’s leases are classified as operating leases. The Company recognizes an asset for the right to use an underlying leased asset for the lease term and records lease liabilities based on the present value of the Company’s obligation to make lease payments under the lease. As the Company’s leases do not indicate an implicit rate, the Company uses a best estimate of its incremental borrowing rate to discount the future lease payments. The Company estimates its incremental borrowing rate based on observable information about risk-free interest rates that are the same tenure as the lease term, adjusted for various factors, including the effects of assumed collateral, the nature of how the risk-free loan is repaid (e.g., amortizing versus bullet), and the Company’s credit risk. The Company evaluates options included in its lease agreements to extend or terminate the lease. The Company will reflect the effects of exercising those options in the lease term when it is reasonably certain that the Company will exercise that option. In assessing whether it is reasonably certain that the Company will exercise an option, the Company considers factors such as: · The lease payments due in any optional period; · Penalties for failure to exercise (or not exercise) the option; · Market factors, such as the availability of similar assets and current rental rates for such assets; · The nature of the underlying leased asset and its importance to the Company’s operations; and · The remaining useful lives of any related leasehold improvements. Lease expense for lease payments is recognized on a straight-line basis over the lease term. Variable lease payments, if any, are recognized in the period when the obligation to make those payments is incurred. Lease incentives received prior to lease commencement are recorded as a reduction in the right-of-use asset. Fixed lease incentives received after lease commencement reduce both the lease liability and the right-of-use asset. The Company has elected an accounting policy to account for the lease and non-lease components as a single lease component.

Revenue

Revenue	6 Months Ended
	Jun. 30, 2019
Revenue Recognition [Abstract]
Revenue	3. Revenue Revenue recognized in the three and six months ended June 30, 2018 and 2019 was $nil. The aggregate transaction price that is allocated to performance obligations that are unsatisfied (or partially unsatisfied) as of June 30, 2019 was $nil.

Net Loss Per Common Share

Net Loss Per Common Share	6 Months Ended
	Jun. 30, 2019
Earnings Per Share [Abstract]
Net Loss Per Common Share	4. Net Loss per Common Share The Company calculates net loss per common share in accordance with ASC 260 “Earnings Per Share” (“ASC 260”). Basic and diluted net loss per common share was determined by dividing net loss applicable to common stockholders by the weighted average number of shares of common stock outstanding during the period. The following potentially dilutive securities have not been included in the computation of diluted net loss per share for the three and six months ended June 30, 2018 and 2019, as the result would be anti-dilutive: June 30, June 30, Stock options 796,856 2,342,268 Convertible preferred stock 1,698 1,698 Series A preferred stock 132,000 132,000 Common stock warrants 7,490,500 7,490,500 Total shares excluded from calculation 8,421,054 9,966,466

Prepaid Expenses and Other Curr

Prepaid Expenses and Other Current Assets	6 Months Ended
	Jun. 30, 2019
Prepaid Expenses And Other Current Assets [Abstract]
Prepaid Expenses and Other Current Assets	5. Prepaid Expenses and Other Current Assets Prepaid expenses and other current assets consisted of the following (in $000s): December 31, June 30, 2018 2019 Research and development tax credit receivable $ 1,148 $ 1,710 Prepayments and VAT receivable 899 1,045 Other current assets 236 236 $ 2,283 $ 2,991 Included in other current assets at June 30, 2019 is $170,000 of receivables. This relates to royalty payments receivable under a December 2005 Asset Purchase Agreement, or APA, whereby Xcyte Therapies, Inc., or Xcyte (a business acquired by the Company in March 2006) sold certain assets and intellectual property to ThermoFisher Scientific

Accrued and Other Liabilities

Accrued and Other Liabilities	6 Months Ended
	Jun. 30, 2019
Payables And Accruals [Abstract]
Accrued and Other Liabilities	6. Accrued and Other Liabilities Accrued and other current liabilities consisted of the following (in $000s): December 31, June 30, 2018 2019 Accrued research and development $ 1,110 $ 1,005 Accrued legal and professional fees 259 182 Other current liabilities 363 207 $ 1,732 $ 1,394

Leases

Leases	6 Months Ended
	Jun. 30, 2019
Leases [Abstract]
Leases	7. Leases The Company has a single lease related to its facility in Dundee, Scotland. As of and for the six months ended June 30, 2019 The Company recognized operating lease expense of $156,329. Cash payments made during the three months ended June 30, 2019 totaled $245,222 and were presented as cash outflows from operating activities. The remaining lease term is approximately 6.3 years as of June 30, 2019. The discount rate used by the Company in determining the lease liability was 12%. Remaining lease payments under the lease are: 2019 $ 160,032 2020 320,065 2021 320,065 2022 320,065 2023 320,065 Thereafter 560,113 $ 2,000,405 As of and for the twelve months ended December 31, 2018 Prior to January 1, 2019, the Company accounted for its Dundee facility lease under ASC 840, Leases The following is a summary of the Company’s future contractual obligations and commitments relating to its facilities leases as at December 31, 2018 (in thousands): ​ Operating 2019 $ 321 2020 321 2021 321 2022 321 2023 321 thereafter 581 Total future minimum lease obligations $ 2,186

Stock Based Compensation

Stock Based Compensation	6 Months Ended
	Jun. 30, 2019
Disclosure Of Compensation Related Costs Share-Based Payments [Abstract]
Stock Based Compensation	8. Stock Based Compensation ASC 718 requires compensation expense associated with share-based awards to be recognized over the requisite service period, which for the Company is the period between the grant date and the date the award vests or becomes exercisable. Most of the awards granted by the Company (and still outstanding) vest ratably over one to four years. The Company recognizes all share-based awards under the straight-line attribution method, assuming that all granted awards will vest. Forfeitures are recognized in the periods when they occur. Stock based compensation has been reported within expense line items on the consolidated statement of operations for the three and six months ended June 30, 2018 and 2019 as shown in the following table (in $000s): Three Months Ended Six Months Ended 2018 2019 2018 2019 General and administrative $ 63 $ 57 $ 122 $ 112 Research and development 23 35 45 66 Stock-based compensation costs before income taxes $ 86 $ 92 $ 167 $ 178 2018 Plan In May 2018, the Company’s stockholders approved the 2018 Equity Incentive Plan (the “2018 Plan”), under which Cyclacel may make equity incentive grants to its officers, employees, directors and consultants. The 2018 Plan replaces the 2015 Equity Incentive Plan (the “2015 Plan”). The 2018 Plan allows for the issuance of up to 1,500,000 shares of the Company’s common stock pursuant to various types of award grants, including stock options and restricted stock units. In addition, the 2018 Plan allows up to 709,889 additional shares to be issued if awards outstanding under the 2018 Plan are cancelled or expire on or after the date of the Company’s 2018 annual meeting of stockholders. As of June 30, 2019, the Company has reserved 152,083 shares of the Company’s common stock under the 2018 Plan, including shares that were available under the 2015 Plan and carried forward to the 2018 Plan. Stock option awards granted under the Company’s equity incentive plans have a maximum life of 10 years and generally vest over a one to four-year period from the date of grant. There were 1,550,270 options granted during the six months ended June 30, 2019. These options had a grant date fair value ranging between $0.52-$0.61 per option. There were 306,304 options granted during the year ended December 31, 2018. These options had grant date fair values ranging between $1.17-$1.29 per option. Of these options, approximately 174,272 are performance based and will vest upon the fulfillment of certain clinical objectives. The Company determined that the satisfaction of one criterion, the commencement of the HEM study by December 31, 2018, occurred as of December 31, 2018, but that the other vesting criteria related to these awards were not probable as of December 31, 2018. As such, the Company recognized compensation cost for these grants under the expectation that 25% of these awards (the portion associated with the HEM study) will vest. There were no stock options exercised during each of the six months ended June 30, 2018 and 2019, respectively. The Company does not expect to be able to benefit from the deduction for stock option exercises that may occur because the company has tax loss carryforwards from prior periods that would be expected to offset any potential taxable income. Outstanding Options A summary of the share option activity and related information is as follows: Number of Weighted Weighted Aggregate Options outstanding at December 31, 2018 831,611 $ 6.68 8.13 $ — Granted 1,550,270 $ 0.71 Cancelled/forfeited (39,613 ) $ 2.76 Options outstanding at June 30, 2019 2,342,268 $ 2.80 8.90 $ — Unvested at June 30, 2019 (1,827,156 ) $ 1.25 9.15 $ — Vested and exercisable at June 30, 2019 515,112 $ 8,28 8.02 $ — The fair value of the stock options granted is calculated using the Black-Scholes option-pricing model as prescribed by ASC 718 using the following assumptions: ​ Year ended Six months Expected term (years) 6 5 – 6 Risk free interest rate 2.730% – 2.855 2.105 – 2.610 Volatility 105% – 107 103 – 110 Expected dividend yield over expected term 0.00% 0.00% Resulting weighted average grant date fair value $1.25 $0.52 – $0.61

Stockholders' Equity

Stockholders' Equity	6 Months Ended
	Jun. 30, 2019
Stockholders' Equity Note [Abstract]
Stockholders Equity	9. Stockholders Equity October 2018 At Market Issuance On October 4, 2018, the Company entered into a Common Stock Sales Agreement, or the Sales Agreement, with H.C. Wainwright & Co., LLC, or Wainwright, as sales agent, pursuant to which Wainwright was authorized to sell shares of common stock, par value $0.001 per share, having an aggregate offering price of up to $5,000,000, by any method that is deemed to be an “at the market offering” as defined in Rule 415 promulgated under the Securities Act of 1933, as amended. Shares sold under the Sales Agreement were offered and sold pursuant to the Company’s previously filed and effective Registration Statement on Form S-3 and a prospectus supplement and accompanying base prospectus. The Company paid Wainwright a commission of 3.0% of the gross sales price per share sold. The Sales Agreement was concluded during the first quarter of 2019, during which the Company sold a further 4,702,527 shares for gross proceeds of approximately $4.3 million. Aggregate net proceeds to the Company were approximately $4.7 million, after deducting commissions and other expenses. Warrants As of June 30, 2019, there were 7,490,500 warrants outstanding, each with an exercise price of $2.00. All such warrants were issued in connection with the July 2017 underwritten public offering and are immediately exercisable. The warrants expire in 2024. The exercise price and the number of shares issuable upon exercise of the warrants is subject to appropriate adjustment in the event of recapitalization events, stock dividends, stock splits, stock combinations, reclassifications, reorganizations or similar events affecting the Company’s common stock. The warrant holders must pay the exercise price in cash upon exercise of the warrants, unless such warrant holders are utilizing the cashless exercise provision of the warrants. On the expiration date, unexercised warrants will automatically be exercised via the “cashless” exercise provision. Prior to the exercise of any warrants to purchase common stock, holders of the warrants will not have any of the rights of holders of the common stock purchasable upon exercise, including the right to vote, except as set forth therein. There was no exercise of warrants during the three and six months ended June 30, 2019. Series A Preferred Stock 8,872 shares of the Company’s Each share of Series A Preferred Stock is convertible at any time at the option of the holder thereof, into a number of shares of common stock determined by dividing $1,000 by the initial conversion price of $2.00 per share, subject to a 4.99% blocker provision, or, upon election by a holder prior to the issuance of shares of Series A Preferred Stock, 9.99%, In the event of a liquidation, the holders of shares of the Series A Preferred Stock shall be permitted to participate on an as-converted-to-common-stock basis in any distribution of assets of the Company. The Company shall not pay any dividends on shares of common stock (other than dividends in the form of common stock) unless and until such time as dividends on each share of Series A Preferred Stock are paid on an as-converted basis. There is no restriction on the Company’s ability to repurchase shares of Series A Preferred Stock while there is any arrearage in the payment of dividends on such shares, and there are no sinking fund provisions applicable to the Series A Preferred Stock. Subject to certain conditions, at any time following the issuance of the Series A Preferred Stock, the Company has the right to cause each holder of the Series A Preferred Stock to convert all or part of such holder’s Series A Preferred Stock in the event that (i) the volume weighted average price of our common stock for 30 consecutive trading days (the “Measurement Period”) exceeds 300% of the initial conversion price of the Series A Preferred Stock (subject to adjustment for forward and reverse stock splits, recapitalizations, stock dividends and similar transactions), (ii) the daily trading volume on each Trading Day during such Measurement Period exceeds $500,000 per trading day and (iii) the holder is not in possession of any information that constitutes or might constitute, material non-public information which was provided by the Company. The right to cause each holder of the Series A Preferred Stock to convert all or part of such holder’s Series A Preferred Stock shall be exercised ratably among the holders of the then outstanding preferred stock. The Series A Preferred Stock has no maturity date, will carry the same dividend rights as the common stock, and with certain exceptions, contains no voting rights. In the event of any liquidation or dissolution of the Company, the Series A Preferred Stock ranks senior to the common stock in the distribution of assets, to the extent legally available for distribution. 6% Convertible Exchangeable Preferred Stock As of June 30, 2019, there were 335,273 The Company may automatically convert the 6% Preferred Stock into common stock if the per share closing price of the Company’s common stock has exceeded $2,961, which is 150% of the conversion price of the 6% Preferred Stock, for at least 20 trading days during any 30-day trading period, ending within five trading days prior to notice of automatic conversion. The 6% Preferred Stock has no maturity date and no voting rights prior to conversion into common stock, except under limited circumstances. The Company may, at its option, redeem the 6% Preferred Stock in whole or in part, out of funds legally available at the redemption price of $10.00 per share. The 6% Preferred Stock is exchangeable, in whole but not in part, at the option of the Company on any dividend payment date beginning on November 1, 2005 (the “Exchange Date”) for the Company’s 6% Convertible Subordinated Debentures (“Debentures”) at the rate of $10.00 principal amount of Debentures for each share of 6% Preferred Stock. The Debentures, if issued, will mature 25 years after the Exchange Date and have terms substantially similar to those of the 6% Preferred Stock. No such exchanges have taken place to date.

Subsequent Events

Subsequent Events	6 Months Ended
	Jun. 30, 2019
Subsequent Events [Abstract]
Subsequent Events	10. Subsequent Events On May 29, 2019, the Board of Directors declared a quarterly cash dividend in the amount of $0.15 per share on the Company’s Preferred Stock. The cash dividend was paid on August 1, 2019 to the holders of record of the Preferred Stock as of the close of business on July 12, 2019. On July 9, 2019, the Company received a written notice from The Nasdaq Stock Market LLC (“Nasdaq”) that the Company has been granted an additional 180 calendar days, or until January 6, 2020, to regain compliance with the minimum $1.00 bid price per share requirement of the Listing Rules of Nasdaq (the “Written Notice”). In accordance with Nasdaq Listing Rule 5810(c)(3)(A), the Company had an initial period of 180 calendar days, or until July 8, 2019, to regain compliance with the minimum closing bid price requirement. The Company did not regain compliance with the minimum closing bid price requirement by July 8, 2019. The Company was previously notified by Nasdaq that it might be afforded a second 180 calendar period to regain compliance with the minimum closing bid price requirement under certain circumstances if the Company notified Nasdaq of its intent to cure the deficiency. As a result, the Company applied for an extension of the cure period, as permitted under the notification. In order to cure the deficiency, the Company indicated that, to the extent necessary, it planned to effect a reverse stock split in order to regain compliance with the minimum closing bid price requirement.

Summary of Significant Accoun_2

Summary of Significant Accounting Policies (Policies)	6 Months Ended
	Jun. 30, 2019
Accounting Policies [Abstract]
Basis of Presentation	Basis of Presentation The consolidated balance sheet as of June 30, 2019, the consolidated statements of operations, comprehensive loss, and stockholders’ equity for the three and six months ended June 30, 2019 and 2018 and the consolidated statements of cash flows for the six months ended June 30, 2019 and 2018, and all related disclosures contained in the accompanying notes, are unaudited. The consolidated balance sheet as of December 31, 2018 is derived from the audited consolidated financial statements included in the Annual Report on Form 10-K for the fiscal year ended December 31, 2018 filed with the Securities and Exchange Commission (“SEC”). The consolidated financial statements are presented on the basis of accounting principles that are generally accepted in the United States (“GAAP”) for interim financial information and in accordance with the rules and regulations of the SEC. Accordingly, they do not include all the information and footnotes required by accounting principles generally accepted in the United States for a complete set of financial statements. In the opinion of management, all adjustments, which include only normal recurring adjustments necessary to present fairly the consolidated balance sheet as of June 30, 2019, and the results of operations and, comprehensive loss for the three and six months ended June 30, 2019, and cash flows for the six months ended June 30, 2019 have been made. The interim results for the three and six months ended June 30, 2019 are not necessarily indicative of the results to be expected for the year ending December 31, 2019 or for any other year. The consolidated financial statements should be read in conjunction with the audited consolidated financial statements and the accompanying notes for the year ended December 31, 2018 that are included in the Company’s Annual Report on Form 10-K filed with the SEC.
Going Concern	Going Concern Management considers that there are no conditions or events, in the aggregate, that raise substantial doubt about the entity’s ability to continue as a going concern for a period of at least one year from the date the financial statements are issued. The Company expects that its cash of $15.2 million as of June 30, 2019 will be sufficient to fund its operating expenses and capital expenditure requirements through the end of 2020. This evaluation is based on relevant conditions and events that are known and reasonably knowable at the date that the financial statements are issued, including: a. The Company’s current financial condition, including its sources of liquidity; b. The Company’s conditional and unconditional obligations due or anticipated within one year; c. The funds necessary to maintain the Company’s operations considering its current financial condition, obligations, and other expected cash flows; and d. Other conditions and events, when considered in conjunction with the above, that may adversely affect the Company’s ability to meet its obligations. The future viability of the Company beyond the end of 2020 is dependent on its ability to raise additional capital to finance its operations.
Recently Issued Accounting Pronouncements	Accounting standards adopted in the period On January 1, 2019, the Company adopted the guidance on accounting for leases (“ASC 842”) in Accounting Standards Update No, 2016-02, Leases, The Company has elected the package of practical expedients permitted in ASC 842. Accordingly, the Company accounted for its existing operating leases as operating leases under the new guidance, without reassessing (a) whether the contracts contain a lease under ASC 842, (b) whether classification of the operating leases would be different in accordance with ASC 842, or (c) whether any unamortized initial direct costs would have met the definition of initial direct costs in ASC 842 at lease commencement. In addition, the Company has elected an accounting policy to not allocate payments made under the lease agreement between lease and non-lease components. The Company transitioned to the new guidance at the adoption date by recognizing a lease liability of $1.5 million for the present value of the remaining minimum rental payments, as defined under prior accounting rules, and a corresponding right-of-use asset. In addition, the Company reclassified an existing deferred rent obligation of $120,000 created under prior accounting rules against the opening right-of-use asset. Because the Company adopted the new leasing guidance on a cumulative catch-up basis effective January 1, 2019, the Company has not recast prior period financial statements for the effects of this new standard. Accordingly, the Company’s financial condition as of December 31, 2018 and June 30, 2019 may not be comparable. Recently Issued Accounting Pronouncements In August 2018, the FASB issued ASU 2018-15, "Customer's Accounting for Implementation Costs Incurred in a Cloud Computing Arrangement that is a Service Contract." ASU 2018-15 requires implementation costs incurred by customers in cloud computing arrangements to be deferred over the non-cancellable term of the cloud computing arrangements plus any optional renewal periods (1) that are reasonably certain to be exercised by the customer or (2) for which exercise of the renewal option is controlled by the cloud service provider. The effective date of this pronouncement is for fiscal years beginning after December 15, 2019, and interim periods within those fiscal years, and early adoption is permitted. The standard can be adopted either using the prospective or retrospective transition approach. The Company is currently evaluating the impact of this pronouncement on the Company's consolidated financial statements and disclosures.
Fair Value of Financial Instruments	Fair Value of Financial Instruments Financial instruments consist of cash equivalents, accounts payable and accrued liabilities. The carrying amounts of cash equivalents, accounts payable and accrued liabilities approximate their respective fair values due to the nature of the accounts, notably their short maturities.
Comprehensive Income (Loss)	Comprehensive Income (Loss) All components of comprehensive income (loss), including net income (loss), are reported in the financial statements in the period in which they are recognized. Comprehensive income (loss) is defined as the change in equity during a period from transactions and other events and circumstances from non-owner sources. Net income (loss) and other comprehensive income (loss), including foreign currency translation adjustments, are reported, net of any related tax effect, to arrive at comprehensive income (loss). No taxes were recorded on items of other comprehensive income (loss). There were no reclassifications out of other comprehensive income (loss) during the three months ended June 30, 2018 and 2019.
Revenue recognition	Revenue recognition With effect from January 1, 2018, the Company recognizes revenue using the five step-model provided in ASC 606, Revenue from Contracts with Customers (1) identify the contract with a customer; (2) identify the performance obligations in the contract; (3) determine the transaction price; (4) allocate the transaction price to the performance obligations in the contract; and (5) recognize revenue when, or as, the Company satisfies a performance obligation. The transaction price includes fixed payments and an estimate of variable consideration, including milestone payments. · Whether achievement of a development milestone is highly susceptible to factors outside the entity’s influence, such as milestones involving the judgment or actions of third parties, including regulatory bodies; · Whether the uncertainty about the achievement of the milestone is not expected to be resolved for a long period of time; · Whether the Company can reasonably predict that a milestone will be achieved based on previous experience; and. · The complexity and inherent uncertainty underlying the achievement of the milestone. The transaction price is allocated to each performance obligation based on the relative selling price of each performance obligation. The best estimate of the selling price is determined after considering all reasonably available information, including market data and conditions, entity-specific factors such as the cost structure of the deliverable and internal profit and pricing objectives. The revenue allocated to each performance obligation is recognized as or when the Company satisfies the performance obligation. The Company recognizes a contract asset, when the value of satisfied (or part satisfied) performance obligations is in excess of the payment due to the Company, and deferred revenue when the amount of unconditional consideration is in excess of the value of satisfied (or part satisfied) performance obligations. Once a right to receive consideration is unconditional, that amount is presented as a receivable. With effect from January 1, 2018, grant revenue, if new grants are obtained, will be presented as a reduction against the related research and development expenses.
Leases	Leases Effective from January 1, 2019, the Company accounts for lease contracts in accordance with ASC 842. As of June 30, 2019, all of the Company’s leases are classified as operating leases. The Company recognizes an asset for the right to use an underlying leased asset for the lease term and records lease liabilities based on the present value of the Company’s obligation to make lease payments under the lease. As the Company’s leases do not indicate an implicit rate, the Company uses a best estimate of its incremental borrowing rate to discount the future lease payments. The Company estimates its incremental borrowing rate based on observable information about risk-free interest rates that are the same tenure as the lease term, adjusted for various factors, including the effects of assumed collateral, the nature of how the risk-free loan is repaid (e.g., amortizing versus bullet), and the Company’s credit risk. The Company evaluates options included in its lease agreements to extend or terminate the lease. The Company will reflect the effects of exercising those options in the lease term when it is reasonably certain that the Company will exercise that option. In assessing whether it is reasonably certain that the Company will exercise an option, the Company considers factors such as: · The lease payments due in any optional period; · Penalties for failure to exercise (or not exercise) the option; · Market factors, such as the availability of similar assets and current rental rates for such assets; · The nature of the underlying leased asset and its importance to the Company’s operations; and · The remaining useful lives of any related leasehold improvements. Lease expense for lease payments is recognized on a straight-line basis over the lease term. Variable lease payments, if any, are recognized in the period when the obligation to make those payments is incurred. Lease incentives received prior to lease commencement are recorded as a reduction in the right-of-use asset. Fixed lease incentives received after lease commencement reduce both the lease liability and the right-of-use asset. The Company has elected an accounting policy to account for the lease and non-lease components as a single lease component.

Net Loss Per Common Share (Tabl

Net Loss Per Common Share (Tables)	6 Months Ended
	Jun. 30, 2019
Earnings Per Share [Abstract]
Schedule of antidilutive shares excluded from computation of diluted net loss per share	June 30, June 30, Stock options 796,856 2,342,268 Convertible preferred stock 1,698 1,698 Series A preferred stock 132,000 132,000 Common stock warrants 7,490,500 7,490,500 Total shares excluded from calculation 8,421,054 9,966,466

Prepaid Expenses and Other Cu_2

Prepaid Expenses and Other Current Assets (Tables)	6 Months Ended
	Jun. 30, 2019
Prepaid Expenses And Other Current Assets [Abstract]
Schedule of prepaid expenses and other current assets	December 31, June 30, 2018 2019 Research and development tax credit receivable $ 1,148 $ 1,710 Prepayments and VAT receivable 899 1,045 Other current assets 236 236 $ 2,283 $ 2,991

Accrued and Other Liabilities (

Accrued and Other Liabilities (Tables)	6 Months Ended
	Jun. 30, 2019
Payables And Accruals [Abstract]
Schedule of accrued and other current liabilities	December 31, June 30, 2018 2019 Accrued research and development $ 1,110 $ 1,005 Accrued legal and professional fees 259 182 Other current liabilities 363 207 $ 1,732 $ 1,394

Leases (Tables)

Leases (Tables)	6 Months Ended
	Jun. 30, 2019
Leases [Abstract]
Schedule of remaining lease payments	2019 $ 160,032 2020 320,065 2021 320,065 2022 320,065 2023 320,065 Thereafter 560,113 $ 2,000,405
Schedule of the Company's contractual obligations and commitments relating to its facilities leases	​ Operating 2019 $ 321 2020 321 2021 321 2022 321 2023 321 thereafter 581 Total future minimum lease obligations $ 2,186

Stock Based Compensation (Table

Stock Based Compensation (Tables)	6 Months Ended
	Jun. 30, 2019
Disclosure Of Compensation Related Costs Share-Based Payments [Abstract]
Schedule of stock based compensation expense	Three Months Ended Six Months Ended 2018 2019 2018 2019 General and administrative $ 63 $ 57 $ 122 $ 112 Research and development 23 35 45 66 Stock-based compensation costs before income taxes $ 86 $ 92 $ 167 $ 178
Schedule of share option activity	Number of Weighted Weighted Aggregate Options outstanding at December 31, 2018 831,611 $ 6.68 8.13 $ — Granted 1,550,270 $ 0.71 Cancelled/forfeited (39,613 ) $ 2.76 Options outstanding at June 30, 2019 2,342,268 $ 2.80 8.90 $ — Unvested at June 30, 2019 (1,827,156 ) $ 1.25 9.15 $ — Vested and exercisable at June 30, 2019 515,112 $ 8,28 8.02 $ —
Schedule of fair value of the stock options granted	​ Year ended Six months Expected term (years) 6 5 – 6 Risk free interest rate 2.730% – 2.855 2.105 – 2.610 Volatility 105% – 107 103 – 110 Expected dividend yield over expected term 0.00% 0.00% Resulting weighted average grant date fair value $1.25 $0.52 – $0.61

Summary of Significant Accoun_3

Summary of Significant Accounting Policies (Detail Textuals) - USD ($)	Jun. 30, 2019	Dec. 31, 2018	Jun. 30, 2018	Dec. 31, 2017
Leases [Line Items]
Lease liability	$ 1,233,000
Cash and cash equivalents	15,159,000	$ 17,504,000	$ 19,824,000	$ 23,910,000
Deferred rent obligation	120,000
New guidance adoption
Leases [Line Items]
Lease liability	$ 1,500,000

Net Loss Per Common Share (Deta

Net Loss Per Common Share (Details) - shares	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total shares excluded from calculation	9,966,466	8,421,054	9,966,466	8,421,054
Stock options
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total shares excluded from calculation	2,342,268	796,856	2,342,268	796,856
Convertible preferred stock
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total shares excluded from calculation	1,698	1,698	1,698	1,698
Series A preferred stock
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total shares excluded from calculation	132,000	132,000	132,000	132,000
Common stock warrants
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total shares excluded from calculation	7,490,500	7,490,500	7,490,500	7,490,500

Prepaid Expenses and Other Cu_3

Prepaid Expenses and Other Current Assets (Details) - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
Prepaid Expense and Other Assets, Current [Abstract]
Research and development tax credit receivable	$ 1,710	$ 1,148
Prepayments and VAT receivable	1,045	899
Other current assets	236	236
Prepaid expenses and other current assets	$ 2,991	$ 2,283

Prepaid Expenses and Other Cu_4

Prepaid Expenses and Other Current Assets (Detail Textuals) - USD ($)	6 Months Ended
	Jun. 30, 2019	Dec. 31, 2018
Prepaid Expense And Other Assets [Line Items]
Other current assets	$ 236,000	$ 236,000
Other Income	170,000
Receivables
Prepaid Expense And Other Assets [Line Items]
Other current assets	$ 170,000

Accrued and Other Liabilities_2

Accrued and Other Liabilities (Details) - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
Payables And Accruals [Abstract]
Accrued research and development	$ 1,005	$ 1,110
Accrued legal and professional fees	182	259
Other current liabilities	207	363
Accrued and other current liabilities	$ 1,394	$ 1,732

Leases (Details)

Leases (Details) $ in Thousands	Jun. 30, 2019USD ($)
Leases [Abstract]
2019	$ 160,032
2020	320,065
2021	320,065
2022	320,065
2023	320,065
Thereafter	560,113
Lease payments, Total	$ 2,000,405

Leases (Details 1)

Leases (Details 1) $ in Thousands	Jun. 30, 2019USD ($)
Operating Lease Obligation
2019	$ 321
2020	321
2021	321
2022	321
2023	321
thereafter	581
Total future minimum lease obligations	$ 2,186

Leases (Detail Textuals)

Leases (Detail Textuals) - USD ($) $ in Thousands	3 Months Ended	6 Months Ended	12 Months Ended
	Jun. 30, 2019	Jun. 30, 2019	Dec. 31, 2018	Dec. 31, 2017
Leases [Abstract]
Operating lease expense		$ 156,329
Operating lease, payments	$ 245,222
Remaining lease term	6 years 3 months 18 days	6 years 3 months 18 days
Discount rate lease liability	12.00%	12.00%
Other rent related expenses			$ 400	$ 500

Stock Based Compensation (Detai

Stock Based Compensation (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Stock-based compensation costs before income taxes	$ 92	$ 86	$ 178	$ 167
General and administrative
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Stock-based compensation costs before income taxes	57	63	112	122
Research and development
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Stock-based compensation costs before income taxes	$ 35	$ 23	$ 66	$ 45

Stock Based Compensation (Det_2

Stock Based Compensation (Details 1) - Stock options - USD ($) $ / shares in Units, $ in Thousands	6 Months Ended	12 Months Ended
	Jun. 30, 2019	Dec. 31, 2018
Number of Options Outstanding
Options outstanding at December 31, 2018	831,611
Granted	1,550,270	306,304
Cancelled/forfeited	(39,613)
Options outstanding at June 30, 2019	2,342,268	831,611
Unvested at June 30, 2019	(1,827,156)
Vested and exercisable at June 30, 2019	515,112
Weighted Average Exercise Price Per Share
Options outstanding at December 31, 2018	$ 6.68
Granted	0.71
Cancelled/forfeited	2.76
Options outstanding at June 30, 2019	2.80	$ 6.68
Unvested at June 30, 2019	1.25
Vested and exercisable at June 30, 2019	$ 8.28
Weighted Average Remaining Contractual Term (Years)
Options outstanding	8 years 10 months 24 days	8 years 1 month 17 days
Unvested at June 30, 2019	9 years 1 month 24 days
Vested and exercisable at June 30, 2019	8 years 7 days
Aggregate Intrinsic Value
Options outstanding	$ 0	$ 0
Vested and exercisable at June 30, 2019	0
Vested and exercisable at March 31, 2019	$ 0

Stock Based Compensation (Det_3

Stock Based Compensation (Details 2) - Stock options - $ / shares	6 Months Ended	12 Months Ended
	Jun. 30, 2019	Dec. 31, 2018
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Expected term (years)		6 years
Expected dividend yield over expected term	0.00%	0.00%
Resulting weighted average grant date fair value		$ 1.25
Minimum
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Expected term (years)	5 years
Risk free interest rate	2.105%	2.73%
Volatility	103.00%	105.00%
Resulting weighted average grant date fair value	$ 0.52	$ 1.17
Maximum
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Expected term (years)	6 years
Risk free interest rate	2.61%	2.855%
Volatility	110.00%	107.00%
Resulting weighted average grant date fair value	$ 0.61	$ 1.29

Stock Based Compensation (Det_4

Stock Based Compensation (Detail Textuals) - $ / shares	6 Months Ended	12 Months Ended
	Jun. 30, 2019	Dec. 31, 2018
Stock options
Stock-based compensation
Options granted (in shares)	1,550,270	306,304
Grant date fair value		$ 1.25
Percentage of vesting of awards	25.00%
Fair value assumptions method used	Black-Scholes option-pricing model
Stock options | Minimum
Stock-based compensation
Grant date fair value	$ 0.52	1.17
Stock options | Maximum
Stock-based compensation
Grant date fair value	$ 0.61	$ 1.29
Performance based options
Stock-based compensation
Options granted (in shares)	174,272
2018 Equity Incentive Plan (the "2018 Plan")
Stock-based compensation
Number of authorized shares	1,500,000
Number of authorized additional shares to be issued	709,889
2018 Equity Incentive Plan (the "2018 Plan") | Minimum
Stock-based compensation
Maximum life of stock option awards granted	1 year
Vesting period	1 year
2018 Equity Incentive Plan (the "2018 Plan") | Maximum
Stock-based compensation
Maximum life of stock option awards granted	4 years
Vesting period	4 years
2018 Equity Incentive Plan (the "2018 Plan") | Stock options
Stock-based compensation
Number of shares reserved for issuance	152,083
Maximum life of stock option awards granted	10 years

Stockholders' Equity (Detail Te

Stockholders' Equity (Detail Textuals) - USD ($)	Oct. 04, 2018	Mar. 31, 2019	Jun. 30, 2019	Dec. 31, 2018
Stockholders Equity [Line Items]
Common stock, par value (in dollars per share)			$ 0.001	$ 0.001
Proceeds from issuance of common stock			$ 4,056,000
Number of warrant outstanding			$ 7,490,500
Warrant exercise price			$ 2
Condition related to exercising warrants			The warrants expire in 2024. Subject to limited exceptions, a holder of warrants will not have the right to exercise any portion of its warrants if the holder (together with such holder's affiliates, and any persons acting as a group together with such holder or any of such holder's affiliates) would beneficially own a number of shares of common stock in excess of 4.99% (or, at the election of the purchaser, 9.99%) of the shares of our Common Stock then outstanding after giving effect to such exercise.
Sales agreement | H.C. Wainwright & Co., LLC
Stockholders Equity [Line Items]
Common stock, par value (in dollars per share)	$ 0.001
Aggregate offering price	$ 5,000,000
Selling commissions, percentage	3.00%
Number of share sold under the sales agreement		4,702,527
Proceeds from issuance of common stock		$ 4,300,000
Net proceeds from issuance of common stock		$ 4,700,000

Stockholders' Equity (Detail _2

Stockholders' Equity (Detail Textuals 1) - $ / shares	1 Months Ended	6 Months Ended	12 Months Ended
	Jul. 31, 2017	Jun. 30, 2019	Dec. 31, 2017	Dec. 31, 2018
Series A convertible preferred stock
Class of Stock [Line Items]
Preferred stock, shares issued	8,872	264		264
Preferred stock, shares outstanding		264		264
Number of shares issued upon conversion	4,304,000
Number of shares converted		132,000	8,608
Price per share used to determine number of shares of common stock	$ 1,000
Conversion price of convertible preferred stock	$ 2
Percentage of blocker provision	4.99%
Conversion percentage	9.99%
Condition related to events occurrence for conversion of preferred stock		(i) the volume weighted average price of our common stock for 30 consecutive trading days (the "Measurement Period") exceeds 300% of the initial conversion price of the Series A Preferred Stock (subject to adjustment for forward and reverse stock splits, recapitalizations, stock dividends and similar transactions), (ii) the daily trading volume on each Trading Day during such Measurement Period exceeds $500,000 per trading day and (iii) the holder is not in possession of any information that constitutes or might constitute, material non-public information which was provided by the Company.
6% Convertible Exchangeable Preferred Stock
Class of Stock [Line Items]
Preferred stock, shares issued		335,273		335,273
Preferred stock, shares outstanding		335,273		335,273
Number of trading days during which closing price of common stock must exceed conversion price for at least 20 days in order for the preferred stock to be convertible		30 days
Dividend rate on convertible exchangeable preferred stock (in percent)		6.00%
Share issue price per share		$ 10
Liquidation preference (in dollars per share)		10
Share Price		$ 2,961
Percentage of closing sales price of common stock that conversion price must exceed in order for preferred stock to be convertible		150.00%
Number of trading days within 30 trading days in which the closing price of common stock must exceed conversion price for preferred stock to be convertible		20 days
Number of trading days prior to notice of automatic conversion		5 days
Redemption price per share (in dollars per share)		$ 10
Interest rate of Convertible Subordinated Debentures (as a percent)		6.00%
Debt principal amount per share, basis for exchange (in dollars per share)		$ 10
Debt instrument, term		25 years

Subsequent Events (Detail Textu

Subsequent Events (Detail Textuals) - $ / shares	1 Months Ended
	May 29, 2019	Jul. 09, 2019
Subsequent Events
Subsequent Event [Line Items]
Minimum bid price Listing of Nasdaq		$ 1
Board of Directors
Subsequent Event [Line Items]
Dividend declared, date	May 29, 2019
Preferred stock dividend declared, amount per share	$ 0.15
Dividends payable, date to be paid	Aug. 1, 2019
Dividend, record date	Jul. 12, 2019