GSK (GSK) F-3ASR Automatic shelf registration (foreign)

Exhibit 22

LIST OF SUBSIDIARY ISSUERS OF GUARANTEED SECURITIES

From time to time, the following 100%-owned subsidiaries of GlaxoSmithKline plc, a public limited company incorporated under the laws of England and Wales (the “Company”), may issue debt securities that are fully and unconditionally guaranteed by the Company, under a registration statement on Form F-3 filed with the Securities and Exchange Commission.

Name of Subsidiary Issuer	Jurisdiction
GlaxoSmithKline Capital Inc.	Delaware
GlaxoSmithKline Capital plc	England and Wales