Itaú Unibanco Holding (ITUB) 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
Estimated average burden
hours per response:		23.8

COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
10X GENOMICS INC	CL A COM	88025U109	65	332	SH		DFND		0	0	332
3M CO	COM	88579Y101	41	206	SH		DFND		0	0	206
908 DEVICES INC	COM	65443P102	38	968	SH		DFND		0	0	968
ABBOTT LABS	COM	002824100	39	333	SH		DFND		0	0	333
ABBVIE INC	COM	00287Y109	39	347	SH		DFND		0	0	347
ACCELERATE DIAGNOSTICS INC	COM	00430H102	17	2,079	SH		DFND		0	0	2,079
ACTIVISION BLIZZARD INC	COM	00507V109	14	149	SH		DFND		0	0	149
ADAPTIMMUNE THERAPEUTICS PLC	SPONDS ADR	00653A107	38	8,892	SH		DFND		0	0	8,892
ADAPTIVE BIOTECHNOLOGIES COR	COM	00650F109	14	345	SH		DFND		0	0	345
ADOBE SYSTEMS INCORPORATED	COM	00724F101	5,551	9,478	SH		DFND		0	0	9,478
ADVANCE AUTO PARTS INC	COM	00751Y106	21	100	SH		DFND		0	0	100
AERCAP HOLDINGS NV	SHS	N00985106	6	123	SH		DFND		0	0	123
AEROVIRONMENT INC	COM	008073108	37	373	SH		DFND		0	0	373
AFYA LTD	CL A COM	G01125106	464	18,000	SH		DFND		0	0	18,000
AGILENT TECHNOLOGIES INC	COM	00846U101	115	779	SH		DFND		0	0	779
AGILYSYS INC	COM	00847J105	42	747	SH		DFND		0	0	747
ALBERTSONS COS INC	COMMON STOCK	013091103	14	709	SH		DFND		0	0	709
ALEXION PHARMACEUTICALS INC	COM	015351109	115	626	SH		DFND		0	0	626
ALIBABA GROUP HLDG LTD	SPONSORED ADS	01609W102	15,146	66,785	SH		DFND		0	0	66,785
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	101	597	SH		DFND		0	0	597
ALPHABET INC	CAP STK CL A	02079K305	44,787	18,342	SH		DFND		219	0	18,123
ALPHABET INC	CAP STK CL C	02079K107	10,374	4,139	SH		DFND		0	0	4,139
AMAZON COM INC	COM	023135106	24,030	6,985	SH		DFND		747	0	6,238
AMBARELLA INC	SHS	G037AX101	46	427	SH		DFND		0	0	427
AMCOR PLC	ORD	G0250X107	31	2,742	SH		DFND		0	0	2,742
AMGEN INC	COM	031162100	39	159	SH		DFND		0	0	159
AMKOR TECHNOLOGY INC	COM	031652100	13	534	SH		DFND		0	0	534
ANTHEM INC	COM	036752103	32	84	SH		DFND		0	0	84
APPLE INC	COM	037833100	15,052	109,903	SH		DFND		483	0	109,420
APPLIED MATLS INC	COM	038222105	32	226	SH		DFND		0	0	226
ARCO PLATFORM LTD	COM CL A	G04553106	2,143	69,882	SH		DFND		0	0	69,882
ARCTURUS THERAPEUTICS HLDGS	COM	03969T109	41	1,205	SH		DFND		0	0	1,205
ARROWHEAD PHARMACEUTICALS IN	COM	04280A100	26	308	SH		DFND		0	0	308
ASANA INC	CL A	04342Y104	62	998	SH		DFND		0	0	998
ASENSUS SURGICAL INC COM	COM	04367G103	45	14,069	SH		DFND		0	0	14,069
ASTRAZENECA PLC	SPONSORED ADR	046353108	1,676	27,984	SH		DFND		0	0	27,984
AUTONATION INC	COM	05329W102	22	237	SH		DFND		0	0	237
BAIDU INC	SPON ADR REP A	056752108	15,515	76,089	SH		DFND		0	0	76,089
BAKER HUGHES A GE CO	CL A	05722G100	10	426	SH		DFND		0	0	426
BALLARD PWR SYS INC NEW	COM	058586108	41	2,268	SH		DFND		0	0	2,268
BANCO BRADESCO S A	SP ADR PFD NEW	059460303	8,999	1,754,147	SH		DFND		0	0	1,754,147
BANCO SANTANDER MEXICO AS	SPONSORED ADS B	05969B103	615	97,853	SH		DFND		0	0	97,853
BERKSHIRE HATHAWAY INC DEL	CL B NEW	084670702	14	50	SH		DFND		0	0	50
BEST BUY INC	COM	086516101	2,444	21,257	SH		DFND		21,257	0	0
BIGCOMMERCE HLDGS INC	COM SER 1	08975P108	45	693	SH		DFND		0	0	693
BIO RAD LABS INC	CL A	090572207	18	28	SH		DFND		0	0	28
BIO TECHNE CORP	COM	09073M104	65	145	SH		DFND		0	0	145
BIOGEN INC	COM	09062X103	50	145	SH		DFND		0	0	145
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	34	408	SH		DFND		0	0	408
BIT MINING LIMITED	SPON ADR REP A	055474100	41	5,154	SH		DFND		0	0	5,154
BLUEPRINT MEDICINES CORP	COM	09627Y109	18	210	SH		DFND		0	0	210
BOOKING HOLDINGS INC	COM	09857L108	21,732	9,932	SH		DFND		0	0	9,932
BOSTON SCIENTIFIC CORP	COM	101137107	44	1,024	SH		DFND		0	0	1,024
BP PLC	SPONSORED ADR	055622104	1,606	60,800	SH		DFND		0	0	60,800
BRISTOL MYERS SQUIBB CO	COM	110122108	132	1,973	SH		DFND		0	0	1,973
BRUKER CORP	COM	116794108	22	290	SH		DFND		0	0	290
BUNGE LIMITED	COM	G16962105	8	106	SH		DFND		0	0	106
C H ROBINSON WORLDWIDE INC	COM NEW	12541W209	3,859	41,200	SH		DFND		0	0	41,200
CANADIAN PAC RY LTD	COM	13645T100	23	303	SH		DFND		0	0	303
CAREDX INC	COM	14167L103	22	245	SH		DFND		0	0	245
CARLYLE GROUP INC COM	COM	14316J108	20	431	SH		DFND		0	0	431
CATALENT INC	COM	148806102	51	470	SH		DFND		0	0	470
CEMEX SAB DE CV	SPON ADR NEW	151290889	8,108	965,295	SH		DFND		0	0	965,295
CHARGEPOINT HOLDINGS INC	COM CL A	15961R105	50	1,451	SH		DFND		0	0	1,451
CHARLES RIV LABS INTL INC	COM	159864107	54	146	SH		DFND		0	0	146
CHARTER COMMUNICATIONS INC N	CL A	16119P108	32	44	SH		DFND		0	0	44
CHEVRON CORP NEW	COM	166764100	14,454	138,000	SH		DFND		0	0	138,000
CHIPOTLE MEXICAN GRILL INC	COM	169656105	6	4	SH		DFND		0	0	4
CIGNA CORP NEW	COM	125523100	14	58	SH		DFND		0	0	58
CITIGROUP INC	COM NEW	172967424	5,464	77,228	SH		DFND		0	0	77,228
CLEAR SECURE INC	COM CL A	18467V109	5,200	130,000	SH		DFND		0	0	130,000
COCA COLA CO	COM	191216100	4,635	85,660	SH		DFND		0	0	85,660
COGNIZANT TECHNOLOGY SOLUTIO	CL A	192446102	31	448	SH		DFND		0	0	448
COINBASE GLOBAL INC	COM CL A	19260Q107	76	300	SH		DFND		300	0	0
COLFAX CORP	COM	194014106	45	992	SH		DFND		0	0	992
COLGATE PALMOLIVE CO	COM	194162103	19	236	SH		DFND		0	0	236
COMCAST CORP NEW	CL A	20030N101	77	1,358	SH		DFND		0	0	1,358
COMPANHIA ENERGETICA DE MINA	SP ADR N-V PFD	204409601	1,826	767,341	SH		DFND		767,341	0	0
CONSTELLATION BRANDS INC	CL A	21036P108	33	142	SH		DFND		0	0	142
COPA HOLDINGS SA	CL A	P31076105	1,636	21,715	SH		DFND		0	0	21,715
CORTEVA INC	COM	22052L104	76	1,721	SH		DFND		0	0	1,721
COSTCO WHSL CORP NEW	COM	22160K105	45	113	SH		DFND		0	0	113
CREDICORP LTD	COM	G2519Y108	763	6,304	SH		DFND		0	0	6,304
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	102	627	SH		DFND		0	0	627
DANAHER CORP DEL	COM	235851102	63	236	SH		DFND		0	0	236
DENALI THERAPEUTICS INC	COM	24823R105	29	369	SH		DFND		0	0	369
DESKTOP METAL INC	COM CL A	25058X105	35	3,050	SH		DFND		0	0	3,050
DEXCOM INC	COM	252131107	43	101	SH		DFND		0	0	101
DICKS SPORTING GOODS INC	COM	253393102	15	150	SH		DFND		0	0	150
DIDI GLOBAL INC	SPONSORED ADS	23292E108	4,119	291,277	SH		DFND		0	0	291,277
DISCOVER FINL SVCS	COM	254709108	2,484	21,000	SH		DFND		0	0	21,000
DISNEY WALT CO	COM DISNEY	254687106	11,352	64,583	SH		DFND		3,001	0	61,582
DLOCAL LTD CLASS A COM	COM	G29018101	11,617	221,142	SH		DFND		0	0	221,142
DOLLAR GEN CORP NEW	COM	256677105	36	166	SH		DFND		0	0	166
DROPBOX INC	CL A	26210C104	43	1,413	SH		DFND		0	0	1,413
DUPONT DE NEMOURS INC	COM	26614N102	53	691	SH		DFND		0	0	691
EBANG INTL HLDGS INC	CL A SHS	G3R33A106	35	11,507	SH		DFND		0	0	11,507
EBAY INC	COM	278642103	21	297	SH		DFND		0	0	297
EDWARDS LIFESCIENCES CORP	COM	28176E108	43	418	SH		DFND		0	0	418
ELECTRAMECCANICA VEHS CORP	COM NEW	284849205	37	8,759	SH		DFND		0	0	8,759
ELECTRONIC ARTS INC	COM	285512109	5	37	SH		DFND		0	0	37
EMBRAER S A	SP ADR REP 4 COM	29082A107	8,057	532,149	SH		DFND		0	0	532,149
ENERGY RECOVERY INC	COM	29270J100	46	2,039	SH		DFND		0	0	2,039
ENERGY TRANSFER EQUITY L P	COM UT LTD PTN	29273V100	35	3,291	SH		DFND		0	0	3,291
EOS ENERGY ENTERPRISES INC	COM CL A	29415C101	39	2,186	SH		DFND		0	0	2,186
EXACT SCIENCES CORP	COM	30063P105	61	487	SH		DFND		0	0	487
EXELIXIS INC	COM	30161Q104	44	2,440	SH		DFND		0	0	2,440
F5 NETWORKS INC	COM	315616102	41	219	SH		DFND		0	0	219
FACEBOOK INC	CALL	30303M902	19	500	SH	Call	DFND		0	0	500
FACEBOOK INC	CL A	30303M102	25,782	74,147	SH		DFND		0	0	74,147
FATE THERAPEUTICS INC	COM	31189P102	24	271	SH		DFND		0	0	271
FIDELITY NATIONAL FINANCIAL	FNF GROUP COM	31620R303	9	197	SH		DFND		0	0	197
FIDELITY NATL INFORMATION SV	COM	31620M106	15	105	SH		DFND		0	0	105
FISERV INC	COM	337738108	24	225	SH		DFND		0	0	225
FOCUS FINL PARTNERS INC	COM CL A	34417P100	2,891	59,600	SH		DFND		0	0	59,600
FREEPORT-MCMORAN INC	CL B	35671D857	29,231	787,690	SH		DFND		0	0	787,690
GENERAL ELECTRIC CO	COM	369604103	361	3,357	SH		DFND		0	0	3,357
GENERAL MLS INC	COM	370334104	23	371	SH		DFND		0	0	371
GENERAL MTRS CO	COM	37045V100	49	832	SH		DFND		0	0	832
GERDAU SA	SPON ADR REP PFD	373737105	7,165	1,214,379	SH		DFND		0	0	1,214,379
GILEAD SCIENCES INC	COM	375558103	1,328	19,286	SH		DFND		18,419	0	867
GLOBANT S A	COM	L44385109	27,333	124,704	SH		DFND		0	0	124,704
GRUPO AEROPORTUARIO DEL CENT	SPON ADR	400501102	589	11,284	SH		DFND		0	0	11,284
GRUPO AEROPORTUARIO DEL SURE	SPON ADR SER B	40051E202	1,063	5,750	SH		DFND		0	0	5,750
GRUPO TELEVISA SA	SPON ADR REP ORD	40049J206	22,274	1,559,827	SH		DFND		0	0	1,559,827
GUARDANT HEALTH INC	COM	40131M109	50	404	SH		DFND		0	0	404
HCA HEALTHCARE INC	COM	40412C101	26	125	SH		DFND		0	0	125
HDFC BANK LTD	ADR REPS 3 SHS	40415F101	3,824	52,300	SH		DFND		0	0	52,300
HILTON WORLDWIDE HLDGS INC	COM	43300A203	23	192	SH		DFND		0	0	192
HOLOGIC INC	COM	436440101	74	1,107	SH		DFND		0	0	1,107
HP INC	COM	40434L105	43	1,420	SH		DFND		0	0	1,420
HUMANA INC	COM	444859102	11	24	SH		DFND		0	0	24
ILLUMINA INC	COM	452327109	158	334	SH		DFND		0	0	334
IMMUNITYBIO INC	COM	45256X103	38	2,671	SH		DFND		0	0	2,671
INCYTE CORP	COM	45337C102	58	686	SH		DFND		0	0	686
INFOSYS LTD	SPONSORED ADR	456788108	613	28,914	SH		DFND		0	0	28,914
INOVIO PHARMACEUTICALS INC	COM NEW	45773H201	38	4,096	SH		DFND		0	0	4,096
INSULET CORP	COM	45784P101	41	151	SH		DFND		0	0	151
INTEGRA LIFESCIENCES HLDGS C	COM NEW	457985208	14	198	SH		DFND		0	0	198
INTELLIA THERAPEUTICS INC	COM	45826J105	47	288	SH		DFND		0	0	288
INTERNATIONAL FLAVORS&FRAGRA	COM	459506101	7	48	SH		DFND		0	0	48
INTUITIVE SURGICAL INC	COM NEW	46120E602	42	46	SH		DFND		0	0	46
INVITAE CORP	COM	46185L103	24	712	SH		DFND		0	0	712
IONIS PHARMACEUTICALS INC	COM	462222100	35	868	SH		DFND		0	0	868
IQVIA HLDGS INC	COM	46266C105	80	331	SH		DFND		0	0	331
IROBOT CORP	COM	462726100	40	424	SH		DFND		0	0	424
ISHARES INC	CALL	464286900	634	3,700	SH	Call	DFND		0	0	3,700
ISHARES INC	MSCI JPN ETF NEW	46434G822	56,537	837,082	SH		DFND		0	0	837,082
ISHARES INC	PUT	464286950	1,066	3,500	SH	Put	DFND		0	0	3,500
ISHARES INC	MSCI PAC JP ETF	464286665	352	6,800	SH		DFND		0	0	6,800
ISHARES INC	MSCI CDA ETF	464286509	3,663	98,270	SH		DFND		0	0	98,270
ISHARES INC	MSCI STH KOR ETF	464286772	2,283	24,500	SH		DFND		0	0	24,500
ISHARES INC	CORE MSCI EMKT	46434G103	723	10,800	SH		DFND		0	0	10,800
ISHARES INC	MSCI EM ASIA ETF	464286426	2,868	31,000	SH		DFND		0	0	31,000
ISHARES INC	MSCI GERMANY ETF	464286806	3,783	109,332	SH		DFND		0	0	109,332
ISHARES INC	MSCI EURZONE ETF	464286608	181	3,673	SH		DFND		0	0	3,673
ISHARES INC	MSCI FRANCE ETF	464286707	3,456	91,300	SH		DFND		0	0	91,300
ISHARES TR	CALL	464287904	23	2,250	SH	Call	DFND		0	0	2,250
ISHARES TR	CHINA LG-CAP ETF	464287184	7,624	164,551	SH		DFND		0	0	164,551
ISHARES TR	MSCI EAFE ETF	464287465	694	8,800	SH		DFND		0	0	8,800
ISHARES TR	PUT	464287956	1	2,500	SH	Put	DFND		0	0	2,500
ISHARES TR	RUSSELL 2000 ETF	464287655	2,386	10,401	SH		DFND		0	0	10,401
ISHARES TR	MSCI ACWI ETF	464288257	4,402	43,500	SH		DFND		0	0	43,500
ISHARES TR	MSCI EURO FL ETF	464289180	45	2,300	SH		DFND		0	0	2,300
ISHARES TR	MSCI CHINA ETF	46429B671	3,957	48,000	SH		DFND		0	0	48,000
ISHARES TR	JPMORGAN USD EMG	464288281	1,687	15,000	SH		DFND		0	0	15,000
ISHARES TR	IBOXX INV CP ETF	464287242	9,311	69,298	SH		DFND		0	0	69,298
ISHARES TR	S&P 500 VAL ETF	464287408	4,355	29,500	SH		DFND		0	0	29,500
ISHARES TR	SHORT TREAS BD	464288679	12,290	111,236	SH		DFND		0	0	111,236
ISHARES TR	10-20 YR TRS ETF	464288653	5,564	37,865	SH		DFND		0	0	37,865
ISHARES TR	US TREAS BD ETF	46429B267	4,306	161,890	SH		DFND		0	0	161,890
ISHARES TR	NA TEC SFTWR ETF	464287515	2,028	5,200	SH		DFND		0	0	5,200
ISHARES TR	RUS 1000 VAL ETF	464287598	973	6,135	SH		DFND		0	0	6,135
ISHARES TR	GL CLEAN ENE ETF	464288224	1,971	84,000	SH		DFND		0	0	84,000
ISHARES TR	US AER DEF ETF	464288760	1,906	17,400	SH		DFND		0	0	17,400
JANUS HENDERSON GROUP PLC	ORD SHS	G4474Y214	14	372	SH		DFND		0	0	372
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	43	241	SH		DFND		0	0	241
JEFFERIES FINL GROUP INC	COM	47233W109	24	707	SH		DFND		0	0	707
JOHNSON & JOHNSON	COM	478160104	494	2,997	SH		DFND		2,762	0	235
JPMORGAN CHASE & CO	COM	46625H100	18,984	122,053	SH		DFND		0	0	122,053
JUNIPER NETWORKS INC	COM	48203R104	39	1,442	SH		DFND		0	0	1,442
KKR & CO INC	CL A	48251W104	16	266	SH		DFND		0	0	266
KRANESHARES TR	CALL	500767906	0	1,050	SH	Call	DFND		0	0	1,050
KROGER CO	COM	501044101	68	1,770	SH		DFND		0	0	1,770
LABORATORY CORP AMER HLDGS	COM NEW	50540R409	108	390	SH		DFND		0	0	390
LEGALZOOM COM INC	COM	52466B103	167	4,408	SH		DFND		0	0	4,408
LENDINGCLUB CORP	COM NEW	52603A208	46	2,514	SH		DFND		0	0	2,514
LILLY ELI & CO	COM	532457108	49	212	SH		DFND		0	0	212
LIVANOVA PLC	SHS	G5509L101	45	530	SH		DFND		0	0	530
LOCKHEED MARTIN CORP	COM	539830109	33	87	SH		DFND		0	0	87
LOUISIANA PAC CORP	COM	546347105	8	133	SH		DFND		0	0	133
LOWES COS INC	COM	548661107	97	499	SH		DFND		0	0	499
LULULEMON ATHLETICA INC	COM	550021109	18	49	SH		DFND		0	0	49
LUMINAR TECHNOLOGIES INC	COM CL A	550424105	37	1,682	SH		DFND		0	0	1,682
MARAVAI LIFESCIENCES HLDGS I	COM CL A	56600D107	18	424	SH		DFND		0	0	424
MARQETA INC	CLASS A COM	57142B104	201	7,147	SH		DFND		0	0	7,147
MASTEC INC	COM	576323109	2,122	20,000	SH		DFND		0	0	20,000
MASTERCARD INCORPORATED	CL A	57636Q104	15	42	SH		DFND		0	0	42
MATCH GROUP INC NEW	COM	57667L107	18	112	SH		DFND		0	0	112
MEDPACE HLDGS INC	COM	58506Q109	24	135	SH		DFND		0	0	135
MEDTRONIC PLC	SHS	G5960L103	39	311	SH		DFND		0	0	311
MERCADOLIBRE INC	COM	58733R102	25,255	16,212	SH		DFND		0	0	16,212
MERCK & CO INC	COM	58933Y105	37	479	SH		DFND		0	0	479
MERCURY SYS INC	COM	589378108	41	621	SH		DFND		0	0	621
METLIFE INC	COM	59156R108	14	242	SH		DFND		0	0	242
MGM RESORTS INTERNATIONAL	COM	552953101	21	486	SH		DFND		0	0	486
MICRON TECHNOLOGY INC	COM	595112103	12	145	SH		DFND		0	0	145
MICROSOFT CORP	COM	594918104	22,846	84,332	SH		DFND		6,666	0	77,666
MICROVISION INC DEL	COM NEW	594960304	32	1,933	SH		DFND		0	0	1,933
MIRATI THERAPEUTICS INC	COM	60468T105	27	168	SH		DFND		0	0	168
MODERNA INC	COM	60770K107	136	580	SH		DFND		0	0	580
MONDAY COM LTD	SHS	M7S64H106	54	242	SH		DFND		0	0	242
MONDELEZ INTL INC	CL A	609207105	24	389	SH		DFND		0	0	389
MONGODB INC	CL A	60937P106	45	124	SH		DFND		0	0	124
MOODYS CORP	COM	615369105	20	55	SH		DFND		0	0	55
MORGAN STANLEY	COM NEW	617446448	10	110	SH		DFND		0	0	110
NANO DIMENSION LTD	SPONSORD ADS NEW	63008G203	43	5,200	SH		DFND		0	0	5,200
NATERA INC	COM	632307104	38	333	SH		DFND		0	0	333
NEKTAR THERAPEUTICS	COM	640268108	33	1,936	SH		DFND		0	0	1,936
NEOGENOMICS INC	COM NEW	64049M209	19	411	SH		DFND		0	0	411
NETFLIX INC	COM	64110L106	16,274	30,809	SH		DFND		2,292	0	28,517
NETSCOUT SYS INC	COM	64115T104	39	1,363	SH		DFND		0	0	1,363
NEUROCRINE BIOSCIENCES INC	COM	64125C109	19	197	SH		DFND		0	0	197
NEXTERA ENERGY INC	COM	65339F101	1,165	15,897	SH		DFND		15,897	0	0
NIKE INC	CL B	654106103	59	381	SH		DFND		228	0	153
NIKOLA CORP	COM	654110105	42	2,349	SH		DFND		0	0	2,349
NORTHROP GRUMMAN CORP	COM	666807102	19	53	SH		DFND		0	0	53
NOVAVAX INC	COM NEW	670002401	37	172	SH		DFND		0	0	172
NRG ENERGY INC	COM NEW	629377508	24	607	SH		DFND		0	0	607
NVIDIA CORP	COM	67066G104	4,145	19,569	SH		DFND		385	0	19,184
NXP SEMICONDUCTORS N V	COM	N6596X109	7	36	SH		DFND		0	0	36
ONECONNECT FINL TECHNOLOGY C	SPONSORD ADS	68248T105	39	3,237	SH		DFND		0	0	3,237
ORCHARD THERAPEUTICS PLC	ADS	68570P101	34	7,825	SH		DFND		0	0	7,825
OSHKOSH CORP	COM	688239201	3,178	25,500	SH		DFND		0	0	25,500
PACIFIC BIOSCIENCES CALIF IN	COM	69404D108	30	868	SH		DFND		0	0	868
PAYPAL HLDGS INC	COM	70450Y103	368	1,263	SH		DFND		880	0	383
PEPSICO INC	COM	713448108	44	299	SH		DFND		0	0	299
PERKINELMER INC	COM	714046109	77	501	SH		DFND		0	0	501
PETROLEO BRASILEIRO SA PETRO	CALL	71654V908	18	1,483	SH	Call	DFND		0	0	1,483
PETROLEO BRASILEIRO SA PETRO	SP ADR NON VTG	71654V101	137,182	11,615,772	SH		DFND		11,615,772	0	0
PETROLEO BRASILEIRO SA PETRO	SPONSORED ADR	71654V408	117,234	9,585,806	SH		DFND		9,585,806	0	0
PFIZER INC	COM	717081103	88	2,237	SH		DFND		0	0	2,237
PG&E CORP	COM	69331C108	10	945	SH		DFND		0	0	945
PHILLIPS 66	COM	718546104	1,742	20,300	SH		DFND		0	0	20,300
PILGRIMS PRIDE CORP	COM	72147K108	12,544	565,568	SH		DFND		0	0	565,568
PINNACLE FINL PARTNERS INC	COM	72346Q104	2,129	24,110	SH		DFND		0	0	24,110
PLAINS ALL AMERN PIPELINE L	UNIT LTD PARTN	726503105	8	689	SH		DFND		0	0	689
PPD INC	COM	69355F102	23	500	SH		DFND		0	0	500
PRA HEALTH SCIENCES INC	COM	69354M108	49	296	SH		DFND		0	0	296
PROCTER AND GAMBLE CO	COM	742718109	60	441	SH		DFND		0	0	441
PROQR THRAPEUTICS N V	SHS EURO	N71542109	43	6,359	SH		DFND		0	0	6,359
PRUDENTIAL FINL INC	COM	744320102	40	394	SH		DFND		0	0	394
QUALCOMM INC	COM	747525103	34	239	SH		DFND		0	0	239
QUEST DIAGNOSTICS INC	COM	74834L100	78	589	SH		DFND		0	0	589
QUIDEL CORP	COM	74838J101	23	179	SH		DFND		0	0	179
RADWARE LTD	ORD	M81873107	43	1,384	SH		DFND		0	0	1,384
REGENERON PHARMACEUTICALS	COM	75886F107	142	254	SH		DFND		0	0	254
REPLIGEN CORP	COM	759916109	37	187	SH		DFND		0	0	187
RIDGEBIO PHARMA INC COM	COM	10806X102	11	180	SH		DFND		0	0	180
ROKU INC	COM CL A	77543R102	18	39	SH		DFND		0	0	39
ROMEO POWER INC	COM	776153108	34	4,158	SH		DFND		0	0	4,158
ROSS STORES INC	COM	778296103	19	156	SH		DFND		0	0	156
SALESFORCE COM INC	COM	79466L302	62	254	SH		DFND		0	0	254
SAREPTA THERAPEUTICS INC	COM	803607100	14	186	SH		DFND		0	0	186
SCHWAB CHARLES CORP NEW	COM	808513105	233	3,200	SH		DFND		0	0	3,200
SEA LTD	ADR	81141R100	3,269	11,904	SH		DFND		0	0	11,904
SEAGEN INC	COM	81181C104	28	180	SH		DFND		0	0	180
SELECT SECTOR SPDR TR	CALL	81369Y906	76	1,800	SH	Call	DFND		0	0	1,800
SELECT SECTOR SPDR TR	CALL	81369Y905	115	2,850	SH	Call	DFND		0	0	2,850
SELECT SECTOR SPDR TR	ENERGY	81369Y506	3,313	61,500	SH		DFND		0	0	61,500
SELECT SECTOR SPDR TR	SBI INT-FINL	81369Y605	8,745	238,354	SH		DFND		0	0	238,354
SELECT SECTOR SPDR TR	TECHNOLOGY	81369Y803	10,311	69,828	SH		DFND		0	0	69,828
SELECT SECTOR SPDR TR	SBI INT-UTILS	81369Y886	6,911	109,300	SH		DFND		0	0	109,300
SELECT SECTOR SPDR TR	SBI INT-INDS	81369Y704	6,813	66,530	SH		DFND		0	0	66,530
SELECT SECTOR SPDR TR	SBI CONS DISCR	81369Y407	11,561	64,750	SH		DFND		0	0	64,750
SELECT SECTOR SPDR TR	SBI MATERIALS	81369Y100	1,844	22,400	SH		DFND		0	0	22,400
SELECT SECTOR SPDR TR	RL EST SEL SEC	81369Y860	5,315	119,900	SH		DFND		0	0	119,900
SENTINELONE INC	CL A	81730H109	5,313	125,000	SH		DFND		0	0	125,000
SERVICENOW INC	COM	81762P102	47	86	SH		DFND		0	0	86
SHERWIN WILLIAMS CO	COM	824348106	20	72	SH		DFND		0	0	72
SILICON LABORATORIES INC	COM	826919102	47	306	SH		DFND		0	0	306
SLACK TECHNOLOGIES INC	COM CL A	83088V102	41	933	SH		DFND		0	0	933
SLM CORP	COM	78442P106	15	719	SH		DFND		0	0	719
SMUCKER J M CO	COM NEW	832696405	33	254	SH		DFND		0	0	254
SOHU COM LTD	SPONSORED ADS	83410S108	44	2,386	SH		DFND		0	0	2,386
SONY CORP	SPONSORED ADR	835699307	491	5,046	SH		DFND		0	0	5,046
SOUTHERN COPPER CORP	COM	84265V105	257	4,000	SH		DFND		0	0	4,000
SPDR GOLD TR	GOLD SHS	78463V107	13,802	83,332	SH		DFND		0	0	83,332
SPDR INDEX SHS FDS	ASIA PACIF ETF	78463X301	2,758	20,500	SH		DFND		0	0	20,500
SPDR S&P 500 ETF TR	CALL	78462F903	3,089	750	SH	Call	DFND		0	0	750
SPDR S&P 500 ETF TR	PUT	78462F953	2,254	5,880	SH	Put	DFND		0	0	5,880
SPDR S&P 500 ETF TR	TR UNIT	78462F103	221,991	518,599	SH		DFND		0	0	518,599
SPDR SER TR	S&P OILGAS EXP	78468R556	3,578	37,000	SH		DFND		0	0	37,000
SPDR SERIES TRUST	S&P METALS MNG	78464A755	495	11,500	SH		DFND		0	0	11,500
SPDR SERIES TRUST	S&P RETAIL ETF	78464A714	2,013	20,700	SH		DFND		0	0	20,700
SQUARE INC	CL A	852234103	34	140	SH		DFND		0	0	140
STANLEY BLACK & DECKER INC	COM	854502101	20	99	SH		DFND		0	0	99
STARBUCKS CORP	COM	855244109	13,011	116,369	SH		DFND		0	0	116,369
STONECO LTD	COM CL A	G85158106	17,710	264,095	SH		DFND		0	0	264,095
SUNNOVA ENERGY INTL INC.	COM	86745K104	1,939	51,480	SH		DFND		0	0	51,480
SUNRUN INC	COM	86771W105	1,936	34,700	SH		DFND		0	0	34,700
SUPER LEAGUE GAMING INC	COM	86804F202	40	7,402	SH		DFND		0	0	7,402
SYNCHRONY FINL	COM	87165B103	2,620	54,000	SH		DFND		0	0	54,000
SYNEOS HEALTH INC	CL A	87166B102	47	526	SH		DFND		0	0	526
SYNNEX CORP	COM	87162W100	14	119	SH		DFND		0	0	119
SYNOPSYS INC	COM	871607107	33	121	SH		DFND		0	0	121
T MOBILE US INC	COM	872590104	52	357	SH		DFND		0	0	357
TAIWAN SEMICONDUCTOR MFG LTD	SPONSORED ADR	874039100	529	4,401	SH		DFND		0	0	4,401
TARGET CORP	COM	87612E106	20	84	SH		DFND		0	0	84
TELADOC HEALTH INC	COM	87918A105	106	640	SH		DFND		0	0	640
TENET HEALTHCARE CORP	COM NEW	88033G407	60	901	SH		DFND		0	0	901
TERNIUM SA	SPON ADR	880890108	23	608	SH		DFND		0	0	608
TESLA INC	COM	88160R101	15,461	22,747	SH		DFND		0	0	22,747
TG THERAPEUTICS INC	COM	88322Q108	15	397	SH		DFND		0	0	397
THERMO FISHER SCIENTIFIC INC	COM	883556102	142	281	SH		DFND		0	0	281
TWILIO INC	CL A	90138F102	28	70	SH		DFND		0	0	70
TWIST BIOSCIENCE CORP	COM	90184D100	28	207	SH		DFND		0	0	207
TWITTER INC	COM	90184L102	16,051	233,272	SH		DFND		0	0	233,272
TYSON FOODS INC	CL A	902494103	19	263	SH		DFND		0	0	263
UBER TECHNOLOGIES INC	COM	90353T100	13	264	SH		DFND		0	0	264
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	29	301	SH		DFND		0	0	301
UNITED THERAPEUTICS CORP DEL	COM	91307C102	44	247	SH		DFND		0	0	247
UNITEDHEALTH GROUP INC	COM	91324P102	85	212	SH		DFND		0	0	212
VALERO ENERGY CORP NEW	COM	91913Y100	1,850	23,700	SH		DFND		0	0	23,700
VANECK VECTORS ETF TR	RUSSIA ETF	92189F403	580	20,000	SH		DFND		0	0	20,000
VANGUARD INDEX FDS	S&P 500 ETF SHS	922908363	574,760	1,460,562	SH		DFND		0	0	1,460,562
VANGUARD INDEX FDS	REAL ESTATE ETF	922908553	3,410	33,500	SH		DFND		0	0	33,500
VANGUARD INTL EQUITY INDEX F	FTSE EUROPE ETF	922042874	116,668	1,734,586	SH		DFND		0	0	1,734,586
VANGUARD INTL EQUITY INDEX F	TT WRLD ST ETF	922042742	15,364	148,288	SH		DFND		0	0	148,288
VARONIS SYS INC	COM	922280102	48	825	SH		DFND		0	0	825
VELODYNE LIDAR INC	COM	92259F101	38	3,578	SH		DFND		0	0	3,578
VERTEX PHARMACEUTICALS INC	COM	92532F100	119	592	SH		DFND		0	0	592
VIRGIN GALACTIC HOLDINGS INC	COM	92766K106	54	1,168	SH		DFND		0	0	1,168
VISA INC	COM CL A	92826C839	3,797	16,238	SH		DFND		0	0	16,238
VISTRA ENERGY CORP	COM	92840M102	6	336	SH		DFND		0	0	336
VONTIER CORPORATION	COM	928881101	3,831	117,600	SH		DFND		0	0	117,600
VUZIX CORP	COM NEW	92921W300	40	2,163	SH		DFND		0	0	2,163
WATERS CORP	COM	941848103	50	145	SH		DFND		0	0	145
WELLS FARGO CO NEW	COM	949746101	2,382	52,600	SH		DFND		0	0	52,600
WESTERN DIGITAL CORP	COM	958102105	13	176	SH		DFND		0	0	176
WHIRLPOOL CORP	COM	963320106	9	43	SH		DFND		0	0	43
WISDOMTREE TR	INDIA ERNGS FD	97717W422	1,185	35,000	SH		DFND		0	0	35,000
WORKHORSE GROUP INC	COM NEW	98138J206	40	2,431	SH		DFND		0	0	2,431
XOMETRY INC	CLASS A COM	98423F109	739	8,454	SH		DFND		0	0	8,454
XP INC	CL A	G98239109	32,304	741,757	SH		DFND		0	0	741,757
XPERI HOLDING CORP	COM	98390M103	41	1,823	SH		DFND		0	0	1,823
XUNLEI LTD	SPONSORED ADR	98419E108	37	8,008	SH		DFND		0	0	8,008
YELP INC	CL A	985817105	40	1,000	SH		DFND		0	0	1,000
ZOETIS INC	CL A	98978V103	5,325	28,575	SH		DFND		0	0	28,575
ZOOM VIDEO COMMUNICATIONS IN	CL A	98980L101	1,577	4,074	SH		DFND		4,010	0	64