Itaú Unibanco Holding (ITUB) 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
Estimated average burden
hours per response:		23.8

COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
10X GENOMICS INC	CL A COM	88025U109	48	332	SH		DFND		0	0	332
908 DEVICES INC	COM	65443P102	48	1,473	SH		DFND		0	0	1,473
ABBOTT LABS	COM	002824100	61	516	SH		DFND		0	0	516
ABBVIE INC	COM	00287Y109	58	539	SH		DFND		0	0	539
ACCELERATE DIAGNOSTICS INC	COM	00430H102	18	3,164	SH		DFND		0	0	3,164
ACTIVISION BLIZZARD INC	COM	00507V109	12	149	SH		DFND		0	0	149
ACUITY BRANDS INC	COM	00508Y102	11	65	SH		DFND		0	0	65
ADAPTIMMUNE THERAPEUTICS PLC	SPONDS ADR	00653A107	69	13,333	SH		DFND		0	0	13,333
ADAPTIVE BIOTECHNOLOGIES COR	COM	00650F109	12	354	SH		DFND		0	0	354
ADOBE SYSTEMS INCORPORATED	COM	00724F101	193	336	SH		DFND		0	0	336
ADVANCE AUTO PARTS INC	COM	00751Y106	103	495	SH		DFND		0	0	495
ADVANCED DRAIN SYS INC DEL	COM	00790R104	17	156	SH		DFND		0	0	156
AEROVIRONMENT INC	COM	008073108	48	559	SH		DFND		0	0	559
AFYA LTD	CL A COM	G01125106	3,989	202,068	SH		DFND		0	0	202,068
AGILENT TECHNOLOGIES INC	COM	00846U101	113	719	SH		DFND		0	0	719
AGILYSYS INC	COM	00847J105	59	1,136	SH		DFND		0	0	1,136
AIR PRODS & CHEMS INC	COM	009158106	103	404	SH		DFND		0	0	404
ALIBABA GROUP HLDG LTD	SPONSORED ADS	01609W102	14,455	97,638	SH		DFND		0	0	97,638
ALLSTATE CORP	COM	020002101	127	997	SH		DFND		0	0	997
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	141	746	SH		DFND		0	0	746
ALPHABET INC	CAP STK CL A	02079K305	22,131	8,278	SH		DFND		174	0	8,104
ALPHABET INC	CAP STK CL C	02079K107	9,984	3,746	SH		DFND		0	0	3,746
AMAZON COM INC	COM	023135106	27,765	8,452	SH		DFND		671	0	7,781
AMBARELLA INC	SHS	G037AX101	100	641	SH		DFND		0	0	641
AMBEV SA	SPONSORED ADR	02319V103	13,307	4,821,212	SH		DFND		0	0	4,821,212
AMCOR PLC	ORD	G0250X107	99	8,569	SH		DFND		0	0	8,569
AMERICA MOVIL SAB DE CV	SPON ADR L SHS	02364W105	32,444	1,836,109	SH		DFND		0	0	1,836,109
AMERICAN WTR WKS CO INC NEW	COM	030420103	57	340	SH		DFND		0	0	340
AMGEN INC	COM	031162100	51	242	SH		DFND		0	0	242
AMKOR TECHNOLOGY INC	COM	031652100	81	3,254	SH		DFND		0	0	3,254
ANTHEM INC	COM	036752103	11	30	SH		DFND		0	0	30
APPLE INC	COM	037833100	17,717	125,210	SH		DFND		483	0	124,727
APPLIED MATLS INC	COM	038222105	16	124	SH		DFND		0	0	124
ARCOS DORADOS HOLDINGS INC	SHS CLASS -A -	G0457F107	0	1	SH		DFND		0	0	1
ARCTURUS THERAPEUTICS HLDGS	COM	03969T109	88	1,834	SH		DFND		0	0	1,834
ARMSTRONG WORLD INDS INC NEW	COM	04247X102	12	122	SH		DFND		0	0	122
ARROWHEAD PHARMACEUTICALS IN	COM	04280A100	20	316	SH		DFND		0	0	316
ASANA INC	CL A	04342Y104	158	1,519	SH		DFND		0	0	1,519
ASENSUS SURGICAL INC COM	COM	04367G103	39	20,812	SH		DFND		0	0	20,812
ASTRAZENECA PLC	SPONSORED ADR	046353108	2,020	33,638	SH		DFND		0	0	33,638
AUTONATION INC	COM	05329W102	92	759	SH		DFND		0	0	759
BAIDU INC	SPON ADR REP A	056752108	14,812	96,338	SH		DFND		0	0	96,338
BALLARD PWR SYS INC NEW	COM	058586108	168	11,970	SH		DFND		0	0	11,970
BANCO BRADESCO S A	SP ADR PFD NEW	059460303	31,515	8,228,514	SH		DFND		0	0	8,228,514
BANCO SANTANDER CHILE NEW	SP ADR REP COM	05965X109	2,636	133,332	SH		DFND		0	0	133,332
BANCO SANTANDER MEXICO AS	SPONSORED ADS B	05969B103	1,155	201,493	SH		DFND		0	0	201,493
BERKSHIRE HATHAWAY INC DEL	CL B NEW	084670702	231	847	SH		DFND		0	0	847
BEST BUY INC	COM	086516101	3,489	33,005	SH		DFND		33,005	0	0
BIGCOMMERCE HLDGS INC	COM SER 1	08975P108	53	1,055	SH		DFND		0	0	1,055
BIO RAD LABS INC	CL A	090572207	22	29	SH		DFND		0	0	29
BIO TECHNE CORP	COM	09073M104	71	147	SH		DFND		0	0	147
BIOGEN INC	COM	09062X103	63	222	SH		DFND		0	0	222
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	49	633	SH		DFND		0	0	633
BIT MINING LIMITED	SPON ADR REP A	055474100	64	7,845	SH		DFND		0	0	7,845
BLOOM ENERGY CORP	COM CL A	093712107	116	6,207	SH		DFND		0	0	6,207
BLOOMIN BRANDS INC	COM	094235108	427	17,085	SH		DFND		0	0	17,085
BLUEPRINT MEDICINES CORP	COM	09627Y109	22	216	SH		DFND		0	0	216
BOOKING HOLDINGS INC	COM	09857L108	4,980	2,098	SH		DFND		0	0	2,098
BOSTON PROPERTIES INC	COM	101121101	25	232	SH		DFND		0	0	232
BOSTON SCIENTIFIC CORP	COM	101137107	69	1,588	SH		DFND		0	0	1,588
BOYD GAMING CORP	COM	103304101	1,455	22,993	SH		DFND		0	0	22,993
BP PLC	SPONSORED ADR	055622104	1,662	60,800	SH		DFND		0	0	60,800
BRF SA	SPONSORED ADR	10552T107	3,550	707,213	SH		DFND		707,213	0	0
BRISTOL MYERS SQUIBB CO	COM	110122108	137	2,308	SH		DFND		0	0	2,308
BRUKER CORP	COM	116794108	23	298	SH		DFND		0	0	298
CAESARS ENTERTAINMENT INC NE	COM	12769G100	1,078	9,599	SH		DFND		0	0	9,599
CANADIAN PAC RY LTD	COM	13645T100	73	1,115	SH		DFND		0	0	1,115
CAPITAL ONE FINL CORP	COM	14040H105	175	1,080	SH		DFND		0	0	1,080
CAREDX INC	COM	14167L103	16	252	SH		DFND		0	0	252
CATALENT INC	COM	148806102	64	482	SH		DFND		0	0	482
CEMEX SAB DE CV	SPON ADR NEW	151290889	28,529	3,978,920	SH		DFND		0	0	3,978,920
CHARGEPOINT HOLDINGS INC	COM CL A	15961R105	44	2,209	SH		DFND		0	0	2,209
CHARLES RIV LABS INTL INC	COM	159864107	92	224	SH		DFND		0	0	224
CHART INDS INC	COM PAR $0.01	16115Q308	151	788	SH		DFND		0	0	788
CHARTER COMMUNICATIONS INC N	CL A	16119P108	97	134	SH		DFND		0	0	134
CHEMOURS CO	COM	163851108	82	2,823	SH		DFND		0	0	2,823
CHEVRON CORP NEW	COM	166764100	7,609	75,000	SH		DFND		0	0	75,000
CISCO SYS INC	COM	17275R102	203	3,733	SH		DFND		0	0	3,733
CITRIX SYS INC	COM	177376100	32	294	SH		DFND		0	0	294
CLEAN HARBORS INC	COM	184496107	11	106	SH		DFND		0	0	106
CME GROUP INC	COM CL A	12572Q105	1,122	5,800	SH		DFND		0	0	5,800
COCA COLA CO	COM	191216100	3,041	57,957	SH		DFND		0	0	57,957
COGNIZANT TECHNOLOGY SOLUTIO	CL A	192446102	52	695	SH		DFND		0	0	695
COINBASE GLOBAL INC	COM CL A	19260Q107	323	1,420	SH		DFND		1,420	0	0
COLFAX CORP	COM	194014106	71	1,539	SH		DFND		0	0	1,539
COLGATE PALMOLIVE CO	COM	194162103	99	1,311	SH		DFND		0	0	1,311
COMCAST CORP NEW	CL A	20030N101	63	1,130	SH		DFND		0	0	1,130
COMPANHIA ENERGETICA DE MINA	SP ADR N-V PFD	204409601	27	10,762	SH		DFND		10,762	0	0
CONSOLIDATED EDISON INC	COM	209115104	28	381	SH		DFND		0	0	381
CORTEVA INC	COM	22052L104	162	3,856	SH		DFND		0	0	3,856
COSTCO WHSL CORP NEW	COM	22160K105	24,022	53,459	SH		DFND		0	0	53,459
CREDICORP LTD	COM	G2519Y108	13,636	122,913	SH		DFND		0	0	122,913
CREE INC	COM	225447101	28	348	SH		DFND		0	0	348
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	90	807	SH		DFND		0	0	807
CUMMINS INC	COM	231021106	103	457	SH		DFND		0	0	457
D R HORTON INC	COM	23331A109	111	1,323	SH		DFND		0	0	1,323
DANAHER CORP DEL	COM	235851102	389	1,278	SH		DFND		0	0	1,278
DARLING INGREDIENTS INC	COM	237266101	31	438	SH		DFND		0	0	438
DELTA AIR LINES INC DEL	COM NEW	247361702	1,065	25,000	SH		DFND		0	0	25,000
DENALI THERAPEUTICS INC	COM	24823R105	19	379	SH		DFND		0	0	379
DESKTOP METAL INC	COM CL A	25058X105	33	4,642	SH		DFND		0	0	4,642
DEXCOM INC	COM	252131107	85	155	SH		DFND		0	0	155
DISCOVER FINL SVCS	COM	254709108	133	1,080	SH		DFND		0	0	1,080
DISNEY WALT CO	COM DISNEY	254687106	36,608	216,399	SH		DFND		2,701	0	213,698
DLOCAL LTD CLASS A COM	COM	G29018101	10,310	188,965	SH		DFND		0	0	188,965
DUPONT DE NEMOURS INC	COM	26614N102	60	878	SH		DFND		0	0	878
DUTCH BROS INC	CL A	26701L100	4,918	113,519	SH		DFND		0	0	113,519
EATON CORP PLC	SHS	G29183103	80	535	SH		DFND		0	0	535
EBANG INTL HLDGS INC	CL A SHS	G3R33A106	32	16,914	SH		DFND		0	0	16,914
EDWARDS LIFESCIENCES CORP	COM	28176E108	73	648	SH		DFND		0	0	648
ELECTRAMECCANICA VEHS CORP	COM NEW	284849205	46	12,981	SH		DFND		0	0	12,981
EMBRAER S A	SP ADR REP 4 COM	29082A107	4,287	252,149	SH		DFND		0	0	252,149
ENERGY RECOVERY INC	COM	29270J100	59	3,103	SH		DFND		0	0	3,103
ENPHASE ENERGY INC	COM	29355A107	52	348	SH		DFND		0	0	348
ENTEGRIS INC	COM	29362U104	27	212	SH		DFND		0	0	212
EOS ENERGY ENTERPRISES INC	COM CL A	29415C101	47	3,328	SH		DFND		0	0	3,328
ESSENTIAL UTILS INC	COM	29670G102	20	433	SH		DFND		0	0	433
EXACT SCIENCES CORP	COM	30063P105	48	500	SH		DFND		0	0	500
EXELIXIS INC	COM	30161Q104	72	3,419	SH		DFND		0	0	3,419
EXPEDIA GROUP INC	COM NEW	30212P303	5,875	35,847	SH		DFND		0	0	35,847
F M C CORP	COM NEW	302491303	88	11,706	SH		DFND		0	0	11,706
F5 NETWORKS INC	COM	315616102	65	329	SH		DFND		0	0	329
FACEBOOK INC	CL A	30303M102	50,010	147,354	SH		DFND		0	0	147,354
FATE THERAPEUTICS INC	COM	31189P102	17	279	SH		DFND		0	0	279
FIDELITY NATL INFORMATION SV	COM	31620M106	74	612	SH		DFND		0	0	612
FIRST SOLAR INC	COM	336433107	27	280	SH		DFND		0	0	280
FISERV INC	COM	337738108	16	150	SH		DFND		0	0	150
FOMENTO ECONOMICO MEXICANO S	SPON ADR UNITS	344419106	21,103	243,348	SH		DFND		0	0	243,348
FOOT LOCKER INC	COM	344849104	464	10,172	SH		DFND		0	0	10,172
FORGEROCK INC	CL A	34631B101	1,280	32,882	SH		DFND		0	0	32,882
FREEPORT-MCMORAN INC	CL B	35671D857	13,000	399,637	SH		DFND		0	0	399,637
FUELCELL ENERGY INC	COM	35952H601	102	15,311	SH		DFND		0	0	15,311
GENERAL ELECTRIC CO	COM	369604301	67	651	SH		DFND		0	0	651
GENERAL MTRS CO	COM	37045V100	180	3,420	SH		DFND		0	0	3,420
GERDAU SA	SPON ADR REP PFD	373737105	21,841	4,439,290	SH		DFND		0	0	4,439,290
GILEAD SCIENCES INC	COM	375558103	477	6,828	SH		DFND		5,875	0	953
GLOBAL X FDS	LITHIUM BTRY ETF	37954Y855	5,983	73,000	SH		DFND		0	0	73,000
GLOBANT S A	COM	L44385109	32,721	116,439	SH		DFND		0	0	116,439
GRAPHIC PACKAGING HLDG CO	COM	388689101	14	710	SH		DFND		0	0	710
GRUPO AEROPORTUARIO DEL SURE	SPON ADR SER B	40051E202	9,196	49,178	SH		DFND		0	0	49,178
GRUPO TELEVISA SA	SPON ADR REP ORD	40049J206	7,817	711,973	SH		DFND		0	0	711,973
GUARDANT HEALTH INC	COM	40131M109	52	415	SH		DFND		0	0	415
HEXCEL CORP NEW	COM	428291108	11	177	SH		DFND		0	0	177
HILTON WORLDWIDE HLDGS INC	COM	43300A203	82	622	SH		DFND		0	0	622
HOLOGIC INC	COM	436440101	80	1,078	SH		DFND		0	0	1,078
HUMANA INC	COM	444859102	9	22	SH		DFND		0	0	22
HYSTER YALE MATLS HANDLING I	CL A	449172105	79	1,580	SH		DFND		0	0	1,580
IDACORP INC	COM	451107106	10	101	SH		DFND		0	0	101
ILLUMINA INC	COM	452327109	159	391	SH		DFND		0	0	391
IMMUNITYBIO INC	COM	45256X103	40	4,065	SH		DFND		0	0	4,065
INCYTE CORP	COM	45337C102	63	919	SH		DFND		0	0	919
INFOSYS LTD	SPONSORED ADR	456788108	604	27,151	SH		DFND		0	0	27,151
INOVIO PHARMACEUTICALS INC	COM NEW	45773H201	45	6,234	SH		DFND		0	0	6,234
INSULET CORP	COM	45784P101	66	231	SH		DFND		0	0	231
INTEGRA LIFESCIENCES HLDGS C	COM NEW	457985208	14	203	SH		DFND		0	0	203
INTELLIA THERAPEUTICS INC	COM	45826J105	40	296	SH		DFND		0	0	296
INTERCONTINENTAL EXCHANGE IN	COM	45866F104	1,943	16,920	SH		DFND		0	0	16,920
INTL PAPER CO	COM	460146103	49	876	SH		DFND		0	0	876
INTUITIVE SURGICAL INC	COM NEW	46120E602	71	71	SH		DFND		0	0	71
INVITAE CORP	COM	46185L103	20	702	SH		DFND		0	0	702
IONIS PHARMACEUTICALS INC	COM	462222100	42	1,241	SH		DFND		0	0	1,241
IQVIA HLDGS INC	COM	46266C105	173	722	SH		DFND		0	0	722
IROBOT CORP	COM	462726100	51	650	SH		DFND		0	0	650
ISHARES INC	CALL	464286900	59	1,500	SH	Call	DFND		0	0	1,500
ISHARES INC	MSCI BRAZIL ETF	464286400	1,445	44,980	SH		DFND		0	0	44,980
ISHARES INC	MSCI JPN ETF NEW	46434G822	5,755	81,920	SH		DFND		0	0	81,920
ISHARES INC	PUT	464286950	2,843	1,500	SH	Put	DFND		0	0	1,500
ISHARES INC	MSCI PAC JP ETF	464286665	332	6,800	SH		DFND		0	0	6,800
ISHARES INC	MSCI CDA ETF	464286509	3,567	98,270	SH		DFND		0	0	98,270
ISHARES INC	MSCI STH KOR ETF	464286772	1,976	24,500	SH		DFND		0	0	24,500
ISHARES INC	CORE MSCI EMKT	46434G103	667	10,800	SH		DFND		0	0	10,800
ISHARES INC	MSCI EM ASIA ETF	464286426	1,604	19,000	SH		DFND		0	0	19,000
ISHARES INC	MSCI GERMANY ETF	464286806	34	1,032	SH		DFND		0	0	1,032
ISHARES TR	CALL	464287904	40	250	SH	Call	DFND		0	0	250
ISHARES TR	CHINA LG-CAP ETF	464287184	12,213	313,715	SH		DFND		0	0	313,715
ISHARES TR	MSCI EAFE ETF	464287465	12,154	155,800	SH		DFND		0	0	155,800
ISHARES TR	MSCI EMG MKT ETF	464287234	4,299	85,331	SH		DFND		0	0	85,331
ISHARES TR	RUSSELL 2000 ETF	464287655	2,253	10,301	SH		DFND		0	0	10,301
ISHARES TR	MSCI ACWI ETF	464288257	4,347	43,500	SH		DFND		0	0	43,500
ISHARES TR	MSCI CHINA ETF	46429B671	3,241	48,000	SH		DFND		0	0	48,000
ISHARES TR	JPMORGAN USD EMG	464288281	1,651	15,000	SH		DFND		0	0	15,000
ISHARES TR	IBOXX INV CP ETF	464287242	2,488	18,700	SH		DFND		0	0	18,700
ISHARES TR	S&P 500 VAL ETF	464287408	4,290	29,500	SH		DFND		0	0	29,500
ISHARES TR	TIPS BD ETF	464287176	4,577	94,000	SH		DFND		0	0	94,000
ISHARES TR	RUS 1000 VAL ETF	464287598	7,674	49,035	SH		DFND		0	0	49,035
ITAU UNIBANCO HLDG S A	SPON ADR REP PFD	465562106	50,898	9,658,135	SH		DFND		0	0	9,658,135
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	49	374	SH		DFND		0	0	374
JOHNSON & JOHNSON	COM	478160104	7,396	45,798	SH		DFND		2,762	0	43,036
JUNIPER NETWORKS INC	COM	48203R104	60	2,195	SH		DFND		0	0	2,195
KANSAS CITY SOUTHERN	COM NEW	485170302	58	215	SH		DFND		0	0	215
KKR & CO INC	CL A	48251W104	5,731	94,135	SH		DFND		0	0	94,135
KRANESHARES TR	CSI CHI INTERNET	500767306	13,999	295,837	SH		DFND		0	0	295,837
L3HARRIS TECHNOLOGIES INC	COM	502431109	99	449	SH		DFND		0	0	449
LABORATORY CORP AMER HLDGS	COM NEW	50540R409	284	1,008	SH		DFND		0	0	1,008
LAUDER ESTEE COS INC	CL A	518439104	1,107	3,690	SH		DFND		0	0	3,690
LENDINGCLUB CORP	COM NEW	52603A208	108	3,826	SH		DFND		0	0	3,826
LENNAR CORP	CL A	526057104	111	1,185	SH		DFND		0	0	1,185
LILLY ELI & CO	COM	532457108	75	324	SH		DFND		0	0	324
LINDE PLC	COM	G5494J103	219	748	SH		DFND		0	0	748
LIVANOVA PLC	SHS	G5509L101	65	822	SH		DFND		0	0	822
LOUISIANA PAC CORP	COM	546347105	12	201	SH		DFND		0	0	201
LOWES COS INC	COM	548661107	174	858	SH		DFND		0	0	858
LULULEMON ATHLETICA INC	COM	550021109	20	49	SH		DFND		0	0	49
LUMINAR TECHNOLOGIES INC	COM CL A	550424105	40	2,559	SH		DFND		0	0	2,559
LUXFER HOLDINGS PLC	SHS	G5698W116	37	1,895	SH		DFND		0	0	1,895
LYONDELLBASELL INDUSTRIES N	SHS - A -	N53745100	122	1,300	SH		DFND		0	0	1,300
MARAVAI LIFESCIENCES HLDGS I	COM CL A	56600D107	21	435	SH		DFND		0	0	435
MASCO CORP	COM	574599106	24	437	SH		DFND		0	0	437
MASTERCARD INCORPORATED	CL A	57636Q104	103	296	SH		DFND		0	0	296
MATCH GROUP INC NEW	COM	57667L107	17	111	SH		DFND		0	0	111
MCAFEE CORP	COM CL A	579063108	1,067	48,249	SH		DFND		0	0	48,249
MEDPACE HLDGS INC	COM	58506Q109	26	139	SH		DFND		0	0	139
MEDTRONIC PLC	SHS	G5960L103	60	482	SH		DFND		0	0	482
MERCADOLIBRE INC	COM	58733R102	17,933	10,678	SH		DFND		0	0	10,678
MERCK & CO INC	COM	58933Y105	56	743	SH		DFND		0	0	743
MERCURY SYS INC	COM	589378108	45	946	SH		DFND		0	0	946
METLIFE INC	COM	59156R108	162	2,620	SH		DFND		0	0	2,620
MICRON TECHNOLOGY INC	COM	595112103	574	8,091	SH		DFND		0	0	8,091
MICROSOFT CORP	COM	594918104	31,549	111,907	SH		DFND		6,288	0	105,619
MICROVISION INC DEL	COM NEW	594960304	33	2,942	SH		DFND		0	0	2,942
MIRATI THERAPEUTICS INC	COM	60468T105	30	172	SH		DFND		0	0	172
MODERNA INC	COM	60770K107	307	798	SH		DFND		0	0	798
MOHAWK INDS INC	COM	608190104	13	75	SH		DFND		0	0	75
MONDELEZ INTL INC	CL A	609207105	22	372	SH		DFND		0	0	372
MONGODB INC	CL A	60937P106	88	187	SH		DFND		0	0	187
MOODYS CORP	COM	615369105	665	1,874	SH		DFND		0	0	1,874
MORGAN STANLEY	COM NEW	617446448	2,919	30,000	SH		DFND		0	0	30,000
NANO DIMENSION LTD	SPONSORD ADS NEW	63008G203	45	7,914	SH		DFND		0	0	7,914
NATERA INC	COM	632307104	38	342	SH		DFND		0	0	342
NATURA &CO HLDG S A	ADS	63884N108	4,274	256,686	SH		DFND		0	0	256,686
NEKTAR THERAPEUTICS	COM	640268108	54	3,002	SH		DFND		0	0	3,002
NEOGENOMICS INC	COM NEW	64049M209	20	422	SH		DFND		0	0	422
NETFLIX INC	COM	64110L106	17,431	28,560	SH		DFND		2,183	0	26,377
NETSCOUT SYS INC	COM	64115T104	56	2,075	SH		DFND		0	0	2,075
NEUROCRINE BIOSCIENCES INC	COM	64125C109	19	203	SH		DFND		0	0	203
NEXTERA ENERGY INC	COM	65339F101	1,723	21,940	SH		DFND		21,940	0	0
NIKE INC	CL B	654106103	9,059	62,380	SH		DFND		228	0	62,152
NIKOLA CORP	COM	654110105	138	12,967	SH		DFND		0	0	12,967
NOVAVAX INC	COM NEW	670002401	37	177	SH		DFND		0	0	177
NVIDIA CORP	COM	67066G104	15,778	76,162	SH		DFND		4,152	0	72,010
NXP SEMICONDUCTORS N V	COM	N6596X109	7,450	38,036	SH		DFND		0	0	38,036
OLIN CORP	COM PAR $1	680665205	125	2,588	SH		DFND		0	0	2,588
ON SEMICONDUCTOR CORP	COM	682189105	36	789	SH		DFND		0	0	789
ONECONNECT FINL TECHNOLOGY C	SPONSORD ADS	68248T105	20	4,927	SH		DFND		0	0	4,927
ORCHARD THERAPEUTICS PLC	ADS	68570P101	27	11,609	SH		DFND		0	0	11,609
OTIS WORLDWIDE CORP	COM	68902V107	94	1,146	SH		DFND		0	0	1,146
OWENS CORNING NEW	COM	690742101	11	133	SH		DFND		0	0	133
PACIFIC BIOSCIENCES CALIF IN	COM	69404D108	22	856	SH		DFND		0	0	856
PAGSEGURO DIGITAL LTD	COM CL A	G68707101	3,588	69,372	SH		DFND		0	0	69,372
PALO ALTO NETWORKS INC	COM	697435105	1,553	3,243	SH		DFND		0	0	3,243
PAYPAL HLDGS INC	COM	70450Y103	1,715	6,590	SH		DFND		751	0	5,839
PENTAIR PLC	SHS	G7S00T104	22	303	SH		DFND		0	0	303
PEPSICO INC	COM	713448108	45	296	SH		DFND		0	0	296
PERKINELMER INC	COM	714046109	112	647	SH		DFND		0	0	647
PETROLEO BRASILEIRO SA PETRO	PUT	71654V958	1,085	1,865	SH	Put	DFND		0	0	1,865
PETROLEO BRASILEIRO SA PETRO	SP ADR NON VTG	71654V101	24,396	2,439,612	SH		DFND		1,944,756	0	494,856
PETROLEO BRASILEIRO SA PETRO	SPONSORED ADR	71654V408	44,122	4,267,128	SH		DFND		333,181	0	3,933,947
PFIZER INC	COM	717081103	290	6,735	SH		DFND		0	0	6,735
PLUG POWER INC	COM NEW	72919P202	158	6,201	SH		DFND		0	0	6,201
POLARIS INDS INC	COM	731068102	14	116	SH		DFND		0	0	116
PPD INC	COM	69355F102	24	513	SH		DFND		0	0	513
PROCAPS GROUP S A	SHS	L7756P102	1,224	120,000	SH		DFND		0	0	120,000
PROCTER AND GAMBLE CO	COM	742718109	142	1,019	SH		DFND		0	0	1,019
PROQR THRAPEUTICS N V	SHS EURO	N71542109	79	9,479	SH		DFND		0	0	9,479
QUALCOMM INC	COM	747525103	31	238	SH		DFND		0	0	238
QUEST DIAGNOSTICS INC	COM	74834L100	196	1,349	SH		DFND		0	0	1,349
QUIDEL CORP	COM	74838J101	26	184	SH		DFND		0	0	184
RADWARE LTD	ORD	M81873107	71	2,106	SH		DFND		0	0	2,106
RAYONIER INC	COM	754907103	10	271	SH		DFND		0	0	271
REGENERON PHARMACEUTICALS	COM	75886F107	337	557	SH		DFND		0	0	557
REPLIGEN CORP	COM	759916109	55	192	SH		DFND		0	0	192
REPUBLIC SVCS INC	COM	760759100	49	406	SH		DFND		0	0	406
RIDGEBIO PHARMA INC COM	COM	10806X102	9	185	SH		DFND		0	0	185
ROKU INC	COM CL A	77543R102	12	38	SH		DFND		0	0	38
ROMEO POWER INC	COM	776153108	31	6,328	SH		DFND		0	0	6,328
ROPER TECHNOLOGIES INC	COM	776696106	12,313	27,600	SH		DFND		0	0	27,600
ROSS STORES INC	COM	778296103	1,985	18,240	SH		DFND		0	0	18,240
ROYAL DUTCH SHELL PLC	SPONS ADR A	780259206	107	2,390	SH		DFND		0	0	2,390
SALESFORCE COM INC	COM	79466L302	4,163	15,348	SH		DFND		0	0	15,348
SAREPTA THERAPEUTICS INC	COM	803607100	18	191	SH		DFND		0	0	191
SCHWAB CHARLES CORP NEW	COM	808513105	1,275	17,500	SH		DFND		0	0	17,500
SEA LTD	ADR	81141R100	9,739	30,556	SH		DFND		0	0	30,556
SEAGATE TECHNOLOGY HLDNGS PL	COM	G7997R103	75	909	SH		DFND		0	0	909
SEAGEN INC	COM	81181C104	48	280	SH		DFND		0	0	280
SELECT SECTOR SPDR TR	CALL	81369Y906	185	1,000	SH	Call	DFND		0	0	1,000
SELECT SECTOR SPDR TR	CALL	81369Y905	0	1	SH		DFND		0	0	1
SELECT SECTOR SPDR TR	ENERGY	81369Y506	10,910	209,442	SH		DFND		0	0	209,442
SELECT SECTOR SPDR TR	SBI INT-FINL	81369Y605	27,305	727,554	SH		DFND		0	0	727,554
SELECT SECTOR SPDR TR	TECHNOLOGY	81369Y803	14,264	95,528	SH		DFND		0	0	95,528
SELECT SECTOR SPDR TR	SBI INT-UTILS	81369Y886	762	11,924	SH		DFND		0	0	11,924
SELECT SECTOR SPDR TR	SBI INT-INDS	81369Y704	22,604	231,030	SH		DFND		0	0	231,030
SELECT SECTOR SPDR TR	SBI MATERIALS	81369Y100	14,912	188,500	SH		DFND		0	0	188,500
SELECT SECTOR SPDR TR	RL EST SEL SEC	81369Y860	7,120	160,180	SH		DFND		0	0	160,180
SERVICENOW INC	COM	81762P102	53	85	SH		DFND		0	0	85
SHERWIN WILLIAMS CO	COM	824348106	98	350	SH		DFND		0	0	350
SILICON LABORATORIES INC	COM	826919102	64	459	SH		DFND		0	0	459
SL GREEN RLTY CORP	COM	78440X804	9	131	SH		DFND		0	0	131
SMUCKER J M CO	COM NEW	832696405	95	792	SH		DFND		0	0	792
SOCIEDAD QUIMICA MINERA DE C	SPON ADR SER B	833635105	7,951	148,000	SH		DFND		0	0	148,000
SOHU COM LTD	SPONSORED ADS	83410S108	76	3,631	SH		DFND		0	0	3,631
SONY CORP	SPONSORED ADR	835699307	536	4,844	SH		DFND		0	0	4,844
SOUTHWEST AIRLS CO	COM	844741108	2,422	47,094	SH		DFND		0	0	47,094
SPDR GOLD TR	GOLD SHS	78463V107	3,148	19,167	SH		DFND		0	0	19,167
SPDR INDEX SHS FDS	ASIA PACIF ETF	78463X301	2,544	20,500	SH		DFND		0	0	20,500
SPDR S&P 500 ETF TR	PUT	78462F953	2,609	5,943	SH	Put	DFND		0	0	5,943
SPDR SER TR	S&P OILGAS EXP	78468R556	8,850	91,500	SH		DFND		0	0	91,500
STARBUCKS CORP	COM	855244109	3,116	28,245	SH		DFND		0	0	28,245
STEEL DYNAMICS INC	COM	858119100	27	463	SH		DFND		0	0	463
STELLANTIS N.V	COM	N82405106	156	8,181	SH		DFND		0	0	8,181
STERICYCLE INC	COM	858912108	10	151	SH		DFND		0	0	151
STERLING CHECK CORP	COM	85917T109	2,715	104,589	SH		DFND		0	0	104,589
SUNRUN INC	COM	86771W105	17	386	SH		DFND		0	0	386
SUPER LEAGUE GAMING INC	COM	86804F202	34	10,866	SH		DFND		0	0	10,866
SUZANO S A SPON	COM	86959K105	10,743	1,074,345	SH		DFND		0	0	1,074,345
SYNCHRONY FINL	COM	87165B103	121	2,474	SH		DFND		0	0	2,474
SYNEOS HEALTH INC	CL A	87166B102	71	815	SH		DFND		0	0	815
SYNOPSYS INC	COM	871607107	107	359	SH		DFND		0	0	359
T MOBILE US INC	COM	872590104	140	1,096	SH		DFND		0	0	1,096
TAIWAN SEMICONDUCTOR MFG LTD	SPONSORED ADR	874039100	296	2,648	SH		DFND		0	0	2,648
TARGET CORP	COM	87612E106	90	392	SH		DFND		0	0	392
TELADOC HEALTH INC	COM	87918A105	82	647	SH		DFND		0	0	647
TENET HEALTHCARE CORP	COM NEW	88033G407	93	1,398	SH		DFND		0	0	1,398
TESLA INC	COM	88160R101	15,805	20,381	SH		DFND		0	0	20,381
TG THERAPEUTICS INC	COM	88322Q108	14	407	SH		DFND		0	0	407
THERMO FISHER SCIENTIFIC INC	COM	883556102	186	325	SH		DFND		0	0	325
TIM S A	COM	88706T108	4,958	461,661	SH		DFND		0	0	461,661
TOAST INC	CL A	888787108	2,607	52,200	SH		DFND		0	0	52,200
TOPBUILD CORP	COM	89055F103	14	67	SH		DFND		0	0	67
TREX CO INC	COM	89531P105	31	305	SH		DFND		0	0	305
TWILIO INC	CL A	90138F102	1,705	5,344	SH		DFND		0	0	5,344
TWIST BIOSCIENCE CORP	COM	90184D100	23	213	SH		DFND		0	0	213
TWITTER INC	COM	90184L102	15,878	262,917	SH		DFND		0	0	262,917
TYSON FOODS INC	CL A	902494103	3,757	47,597	SH		DFND		0	0	47,597
UBER TECHNOLOGIES INC	COM	90353T100	85	1,893	SH		DFND		0	0	1,893
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	28	309	SH		DFND		0	0	309
UNITED THERAPEUTICS CORP DEL	COM	91307C102	71	383	SH		DFND		0	0	383
UNITEDHEALTH GROUP INC	COM	91324P102	2,998	7,673	SH		DFND		0	0	7,673
UNIVERSAL DISPLAY CORP	COM	91347P105	23	133	SH		DFND		0	0	133
US FOODS HLDG CORP	COM	912008109	2,073	59,808	SH		DFND		0	0	59,808
VALE S A	SPONSORED ADS	91912E105	54,408	3,900,194	SH		DFND		0	0	3,900,194
VANECK VECTORS ETF TR	RUSSIA ETF	92189F403	5,154	170,000	SH		DFND		0	0	170,000
VANGUARD INDEX FDS	S&P 500 ETF SHS	922908363	665,854	1,688,272	SH		DFND		0	0	1,688,272
VANGUARD INDEX FDS	REAL ESTATE ETF	922908553	8,957	88,000	SH		DFND		0	0	88,000
VANGUARD INTL EQUITY INDEX F	TT WRLD ST ETF	922042742	15,100	148,288	SH		DFND		0	0	148,288
VARONIS SYS INC	COM	922280102	76	1,255	SH		DFND		0	0	1,255
VELODYNE LIDAR INC	COM	92259F101	32	5,446	SH		DFND		0	0	5,446
VERTEX PHARMACEUTICALS INC	COM	92532F100	125	689	SH		DFND		0	0	689
VICTORIAS SECRET AND CO	COMMON STOCK	926400102	781	14,132	SH		DFND		0	0	14,132
VIPSHOP HLDGS LTD	SPONSORED ADR	92763W103	161	14,491	SH		DFND		0	0	14,491
VIRGIN GALACTIC HOLDINGS INC	COM	92766K106	45	1,778	SH		DFND		0	0	1,778
VISA INC	COM CL A	92826C839	152	683	SH		DFND		0	0	683
VMWARE INC	CL A COM	928563402	38	256	SH		DFND		0	0	256
VORNADO RLTY TR	SH BEN INT	929042109	14	330	SH		DFND		0	0	330
VUZIX CORP	COM NEW	92921W300	34	3,292	SH		DFND		0	0	3,292
WABTEC CORP	COM	929740108	42	488	SH		DFND		0	0	488
WALMART INC	COM	931142103	2,153	15,447	SH		DFND		0	0	15,447
WASTE MGMT INC DEL	COM	94106L109	121	813	SH		DFND		0	0	813
WATERS CORP	COM	941848103	79	222	SH		DFND		0	0	222
WELLS FARGO CO NEW	COM	949746101	2,604	56,100	SH		DFND		0	0	56,100
WESTLAKE CHEM CORP	COM	960413102	85	933	SH		DFND		0	0	933
WESTPORT FUEL SYSTEMS INC	COM NEW	960908309	73	22,315	SH		DFND		0	0	22,315
WEYERHAEUSER CO	COM	962166104	66	1,866	SH		DFND		0	0	1,866
WHIRLPOOL CORP	COM	963320106	89	436	SH		DFND		0	0	436
WISDOMTREE TR	INDIA ERNGS FD	97717W422	1,309	35,000	SH		DFND		0	0	35,000
WORKHORSE GROUP INC	COM NEW	98138J206	28	3,700	SH		DFND		0	0	3,700
WORTHINGTON INDS INC	COM	981811102	74	1,404	SH		DFND		0	0	1,404
XCEL ENERGY INC	COM	98389B100	33	529	SH		DFND		0	0	529
XILINX INC	COM	983919101	2,567	17,000	SH		DFND		0	0	17,000
XP INC	CL A	G98239109	3,110	77,415	SH		DFND		0	0	77,415
XPERI HOLDING CORP	COM	98390M103	52	2,775	SH		DFND		0	0	2,775
XUNLEI LTD	SPONSORED ADR	98419E108	34	11,788	SH		DFND		0	0	11,788
XYLEM INC	COM	98419M100	37	299	SH		DFND		0	0	299
YELP INC	CL A	985817105	57	1,522	SH		DFND		0	0	1,522
ZOETIS INC	CL A	98978V103	3,410	17,563	SH		DFND		0	0	17,563
ZOOM VIDEO COMMUNICATIONS IN	CL A	98980L101	1,019	3,897	SH		DFND		3,834	0	63