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Exhibit 8.1 – List of Significant Subsidiaries and
Consolidated Affiliated Entity
LIST OF SIGNIFICANT SUBSIDIARIES AND
CONSOLIDATED AFFILIATED ENTITIES
Significant Subsidiaries
Name of Company | Jurisdiction of Incorporation | Percentage of Equity Owned | ||||
Medicure International, Inc. | Barbados | 100 | % | |||
Medicure Pharma Inc. | United States (Delaware) | 100 | % | |||
Medicure U.S.A. Inc. | United States (Delaware) | 100 | % | |||
Medicure Pharma Europe Ltd | Ireland | 100 | % | |||
Medicure Mauritius Limited | Mauritius | 100 | % | |||
Apigen Investments Limited | Mauritius | 100 | % |
All significant subsidiaries do business under their respective legal names.