Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the Registration Statement (Form S-8) pertaining to the EPIRUS Biopharmaceuticals, Inc. 2015 Equity Incentive Plan and the EPIRUS Biopharmaceuticals, Inc. 2015 Employee Stock Purchase Plan of our report dated March 28, 2016, with respect to the consolidated financial statements of EPIRUS Biopharmaceuticals, Inc. and the effectiveness of internal control over financial reporting of EPIRUS Biopharmaceuticals, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2015, filed with the Securities and Exchange Commission.
/s/ Ernst & Young LLP
Boston, Massachusetts
March 28, 2016
