Page | ||||
1. DEFINITIONS | 1 | |||
2. ADMINISTRATION OF THE COLLABORATION | 27 | |||
2.1Joint Steering Committee | 27 | |||
2.2Joint Project Team | 31 | |||
2.3Joint Development Committee | 34 | |||
2.4Alliance Management | 36 | |||
3. RESEARCH PROGRAM | 36 | |||
3.1Implementation of the Research Program | 36 | |||
3.2Technology Transfer Activities | 36 | |||
3.3Research Projects | 37 | |||
3.4Annual Research Plans | 37 | |||
3.5Conduct of Research Program | 38 | |||
3.6Records | 38 | |||
3.7Designation of Program Targets | 39 | |||
3.8Replacement of Program Targets; Target Exclusivity List; ARCHEMIX Retained Rights | 41 | |||
3.9ARCHEMIX Internal Program Targets | 42 | |||
3.10Identification of Lead Compounds and Optimized Lead Compounds | 46 | |||
3.11Development Candidates | 47 | |||
3.12MERCK Decision Not to Go Forward | 47 | |||
3.13Supply of Proprietary Materials | 47 | |||
3.14Research Program Term | 48 | |||
3.15Conduct of Target Validation Activities | 48 | |||
4. DEVELOPMENT PROGRAM; COMMERCIALIZATION OF PRODUCTS | 48 | |||
4.1Objectives of the Development Program | 48 | |||
4.2Responsibility for Development of Development Candidates and Commercialization of Products | 48 | |||
4.3Annual Development Plans | 49 | |||
4.4Product Commercialization Plans | 50 | |||
4.5Manufacture and Supply of Products for Development and Commercialization | 50 | |||
4.6Development and Commercialization Diligence | 51 | |||
4.7Compliance | 51 | |||
4.8Cooperation | 52 | |||
4.9Exchange of Reports; Information; Updates | 52 | |||
4.10Development and Commercialization Rights and Restrictions | 53 | |||
5. EQUITY PURCHASE RIGHT | 60 | |||
5.1Purchase of Equity | 60 | |||
5.2Equity Purchase Right | 61 | |||
6. PAYMENTS | 63 | |||
6.1SELEX License Maintenance Fee | 63 | |||
6.2Research License Maintenance Fee | 63 | |||
6.3Compound Option Exercise Fees | 63 | |||
6.4R&D Funding | 64 |
i
Page | ||||
6.5Milestone Payments | 65 | |||
6.6Payment of Royalties; Royalty Rates; Accounting and Records | 67 | |||
6.7Net Income Payments | 72 | |||
6.8Payments | 73 | |||
6.9Taxes | 73 | |||
6.10US Partnership | 73 | |||
6.11Foreign Currency Exchange | 74 | |||
7. TREATMENT OF CONFIDENTIAL INFORMATION; PUBLICITY; NON-SOLICITATION | 75 | |||
7.1Confidentiality | 75 | |||
7.2Publicity | 76 | |||
7.3Publications and Presentations | 77 | |||
7.4Prohibition on Solicitation | 77 | |||
8. LICENSE GRANTS; EXCLUSIVITY | 78 | |||
8.1SELEX License; Research and Development Licenses | 78 | |||
8.2Commercialization License | 83 | |||
8.3Limitation on License Grants | 84 | |||
8.4Right to Sublicense | 84 | |||
8.5Right to Subcontract | 84 | |||
8.6No Other Rights | 85 | |||
8.7Exclusivity | 85 | |||
9. INTELLECTUAL PROPERTY RIGHTS | 85 | |||
9.1ARCHEMIX Intellectual Property Rights | 85 | |||
9.2MERCK Intellectual Property Rights | 85 | |||
9.3Joint Technology and Joint Co-Developed Program Technology Rights | 85 | |||
9.4Patent Coordinators | 86 | |||
9.5Inventorship | 86 | |||
9.6Cooperation | 86 | |||
10. FILING, PROSECUTION AND MAINTENANCE OF PATENT RIGHTS | 86 | |||
10.1Patent Filing, Prosecution and Maintenance | 86 | |||
10.2Legal Actions | 89 | |||
10.3Trademark and Copyright Prosecution, Defense and Enforcement | 93 | |||
10.4Effect of Challenge | 93 | |||
11. TERM AND TERMINATION | 94 | |||
11.1Term | 94 | |||
11.2Termination | 94 | |||
11.3Consequences of Termination of Agreement | 95 | |||
11.4Surviving Provisions | 98 | |||
12. REPRESENTATIONS AND WARRANTIES AND COVENANTS | 99 | |||
12.1Mutual Representations and Warranties | 99 | |||
12.2ARCHEMIX’ Representations and Warranties | 99 | |||
12.3Acknowledgment and Covenant of MERCK | 100 | |||
13. INDEMNIFICATION | 101 | |||
13.1Indemnification of MERCK by ARCHEMIX | 101 | |||
13.2Indemnification of ARCHEMIX by MERCK | 101 | |||
13.3Indemnification of Gilead and UTC by MERCK | 101 |
ii
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13.4Conditions to Indemnification | 102 | |||
13.5Warranty Disclaimer | 102 | |||
13.6No Warranty of Success | 102 | |||
13.7Limited Liability | 102 | |||
14. MISCELLANEOUS | 103 | |||
14.1Arbitration | 103 | |||
14.2Change of Control | 104 | |||
14.3Notices | 106 | |||
14.4Governing Law | 107 | |||
14.5Binding Effect | 107 | |||
14.6Headings | 107 | |||
14.7Counterparts | 107 | |||
14.8Amendment; Waiver | 108 | |||
14.9No Third Party Beneficiaries | 108 | |||
14.10Purposes and Scope | 108 | |||
14.11Assignment and Successors | 108 | |||
14.12Force Majeure | 108 | |||
14.13Interpretation | 108 | |||
14.14Integration; Severability | 109 | |||
14.15Further Assurances | 109 |
iii
Exhibit A | SELEX Technology Transfer Plan | |
Exhibit B | Form of Common Stock Purchase Agreement | |
List of Schedules | ||
Schedule 1A | Optimized Lead Compound Selection Criteria- MERCK Funded Research Projects; MERCK Internal Research Projects | |
Schedule 1B | Optimized Lead Compound Selection Criteria — ARCHEMIX Internal Research Projects | |
Schedule 2A | Target Exclusivity List | |
Schedule 2B | ARCHEMIX Internal Program Targets | |
Schedule 3 | Licensed Patent Rights | |
Schedule 4 | Excluded Aptamers | |
Schedule 5A | Development Candidate Selection Criteria — MERCK Funded Research Projects; MERCK Internal Research Projects | |
Schedule 5B | Development Candidate Selection Criteria — ARCHEMIX Internal Research Projects | |
Schedule 6 | Form of Press Release | |
Schedule 7 | Regional Offices or Countries in which Patent Applications are to be Nationalized or Otherwise Prosecuted, Filed and Maintained | |
Schedule 8 | Material Terms to be Included in Form of Co-Promotion Agreement | |
Schedule 9 | MERCK’s Standard Exchange Rate Methodology Applied in Its External Reporting | |
Schedule 10 | Program Chemistries | |
Schedule 11 | Calculation of Net Income | |
Schedule 12 | Form of Materials Transfer Agreement | |
Schedule 13 | Co-Development Costs and Guidelines for their Allocation and Co-Development Regulatory Costs |
iv
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
Definition | Section | |
Annual Reconciliation Statement | 6.4.1(b) | |
Additional Research Request | 3.9.2(a) | |
ARCHEMIX Change of Control Notice | 13.2.1(a) | |
ARCHEMIX Indemnitees | 12.2 | |
ARCHEMIX Internal Program Target Notice | 3.9.3 |
25
Definition | Section | |
Backup Compound Candidate | 3.9.1(b) | |
Backup Compound Candidate Evaluation Period | 3.9.1(b) | |
Backup Compound Candidate Notice | 3.9.1(b) | |
Backup Compound Candidate Option | 3.9.1(b) | |
Claims | 12.1 | |
Co-Developed Development Candidate | 4.10.2(a) | |
Co-Development and Co-Promotion Option | 4.10.2(a) | |
Co-Development and Co-Promotion Option Notice | 4.10.2(a) | |
Co-Development Option Exercise Period | 4.10.2(a) | |
Collaboration Manager | 2.4 | |
Competing Aptamer Product | 7.10.1(d) | |
Co-Promotion Agreement | 4.10.2(c) | |
Co-Promotion Option Period | 4.11.1 | |
Designated Senior Officers | 2.1.6 | |
Designation Notice | 7.1.2(c)(i) | |
Dispute | 13.1.1 | |
Disputed Matter | 2.1.6 | |
Evaluation Period | 3.9.1(a) | |
Expert | 14.1.2(a) | |
Filing Party | 10.1.4 | |
Generic Product | 6.6.1(e) | |
Gilead Indemnitee | 13.3 | |
Indemnified Party | 13.4 | |
Indemnifying Party | 13.4 | |
Infringement | 10.2.1(a) | |
Infringement Notice | 10.2.1(a) | |
IPO Effective Date | 5.5.2(c) | |
JCC | Schedule 9 | |
JPT | 2.2.1 | |
JPT Term | 2.2.1 | |
JSC Term | 2.1.1 | |
Late Stage Development Activities | 4.10.6(b) | |
Losses | 12.1 | |
MERCK Change of Control Notice | 13.2.2(a) | |
MERCK Contribution | 6.4.1(b) | |
MERCK Indemnitees | 13.1 | |
MERCK Internal Program Target Requests | 3.7.2(c) | |
MERCK IPO Shares | 5.2.2(b) | |
MERCK IPO Share Amount | 5.2.2(c) | |
MERCK Private Placement Shares | 5.2.2(c)) | |
MERCK Private Placement Share Amount | 5.2.2(b) | |
MTA | 3.9.1(a) | |
Net Income Payments | 6.7.1 | |
Non-Filing Party | 10.1.4 | |
Opting-Out Party | 4.10.7(d) |
26
Definition | Section | |
Option Fee | 6.3 | |
Option Exercise Fee | 6.3 | |
Opt-Out Right | 4.10.6(d) | |
Opt-Out Right Notice | 4.10.6(d) | |
Opt-Out Right Notice Period | 4.10.6(d) | |
Patent Coordinator | 8.4 | |
Primary Compound Candidate | 3.9.1(a) | |
Primary Compound Candidate Notice | 3.9.1(a) | |
Primary Compound Candidate Option | 3.9.1(a) | |
Private Placement | 5.2.1 | |
Private Placement Closing | 5.2.2(d) | |
Private Placement Closing Date | 5.2.2(d) | |
Private Placement Purchase Price | 5.2.2(c) | |
Purchase Notice | 5.2.2(c) | |
Qualified IPO Notice | 5.2.2(a) | |
Qualified IPO Purchase Price | 5.2.2(c) | |
Requested ARCHEMIX Activities | 3.9.2(a) | |
Requested Chemistry | 6.6.1(c) | |
Recipient Party | 3.13 | |
Roll-Over Payment | 4.10.7(c) | |
SELEX License | 7.1.1(a)(i) | |
Separation Date | 4.10.6(d) | |
Sole Developing Party | 4.10.6(d) | |
Technology Transfer Activities | 3.2 | |
Technology Transfer Costs | 3.2 | |
Technology Transfer Term | 3.2 | |
Term | 11.1 | |
Third Party Chemistry Payments | 6.6.1(c) | |
Third Party Costs | 7.5.3 | |
Third Party Payments | 6.6.1(c) | |
Transferring Party | 3.13 |
27
28
29
30
31
32
33
34
35
36
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39
40
41
42
43
44
45
46
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49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
Milestone Event | Milestone Payment | |
1. [***] | $[***] | |
2. [***] | $[***] | |
3. [***] | $[***] | |
4. [***] | $[***] | |
5. [***] | $[***] | |
6. [***] | $[***] | |
7. [***] | $[***] | |
8. [***] | $[***] | |
9. [***] | $[***] | |
10. [***] | $[***] | |
11. [***] | $[***] | |
12. [***] | $[***] | |
13. [***] | $[***] | |
14. [***] | $[***] | |
15. [***] | $[***] | |
16. [***] | $[***] |
66
Annual Net Sales | Royalty Rate (%) | |
[***] | [***]% | |
[***] | [***]% | |
[***] | [***]% | |
[***] | [***]% |
67
68
69
70
71
72
73
74
set forth onSchedule 9 attached hereto or any other mutually agreed upon source, for such Calendar Quarter).
PUBLICITY; NON-SOLICITATION.
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If to MERCK: | If to ARCHEMIX: | |||
Merck KGaA | Archemix Corp. | |||
Legal Department | 300 Third Street | |||
Frankfurter Str. 250 | Cambridge, MA 02142 | |||
64293 Darmstadt | Tel: (617) 621-7700 | |||
Germany | Fax: (617) 621-9300 | |||
Tel: +49 6151 72 0 | Attention: Chief Executive Officer | |||
Fax: +49 6151 72 [***] | Attention: General Counsel | |||
With a copy to: | ||||
Mintz, Levin, Cohn, Ferris, Glovsky | ||||
and Popeo, P.C. | ||||
One Financial Center | ||||
Boston, Massachusetts 02111 | ||||
Attention: John J. Cheney, Esq. | ||||
Tel: (617) 542-6000 | ||||
Fax: (617) 542-2241 |
107
108
109
ARCHEMIX CORP. | ||||||
By: | ||||||
Name: | ||||||
Title: | ||||||
MERCK KGaA | ||||||
ppa. i.V. | ||||||
By: | ||||||
Name: | ||||||
Title: | Senior Executive Legal Counsel Vice President |
110
Location | Archemix, Cambridge MA | |||||||||||
Staffing | • | Merck: [***], [***] (or [***]) | ||||||||||
Requirements | • | Archemix: [***] , [***] | ||||||||||
Duration | • | [***] at Archemix | ||||||||||
o | May be acceptable for [***] to spend [***], [***] to stay [***] | |||||||||||
• | Archemix may provide subsequent consultation on an as needed basisviaphone, e-mail, e-room, or in person. | |||||||||||
Components of classroom training | • | Archemix scientists to provide [***] covering: | ||||||||||
o | [***]: what is it? | |||||||||||
o | [***] | |||||||||||
o | [***] | |||||||||||
o | [***] | |||||||||||
§ | What [***] of [***] are used | |||||||||||
§ | What [***] choice | |||||||||||
o | [***] for [***] | |||||||||||
§ | [***] for [***] | |||||||||||
§ | [***] for [***] | |||||||||||
o | [***] for [***] the [***] of a [***] | |||||||||||
o | [***] | |||||||||||
o | [***] | |||||||||||
o | Concepts to [***] when [***] | |||||||||||
Components of laboratory training | • | [***] | ||||||||||
• | [***] | |||||||||||
• | [***] and [***] for [***] | |||||||||||
• | [***] | |||||||||||
Materials to be provided to Merck | • | [***] materials from [***] | ||||||||||
KGaA | • | [***] for all [***] of [***] from [***] [***] through [***] | ||||||||||
• | [***] and [***] for [***] | |||||||||||
Required equipment | • | [***] | ||||||||||
(Merck site) | • | [***] | ||||||||||
• | [***] | |||||||||||
• | [***] with [***] for [***], [***] | |||||||||||
• | [***] and [***] | |||||||||||
• | [***] | |||||||||||
• | [***] with [***] | |||||||||||
• | Other standard laboratory equipment (e.g., [***], [***], etc.) |
Page | ||||
SECTION 1 DEFINITIONS | 1 | |||
SECTION 2 AUTHORIZATION, PURCHASE AND SALE OF THE SHARES | 3 | |||
2.1Purchase and Sale of the Shares | 3 | |||
2.2Closing | 3 | |||
SECTION 3 REPRESENTATIONS AND WARRANTIES AND CERTAIN COVENANTS OF THE COMPANY | 4 | |||
3.1Organization, Qualifications and Corporate Power | 4 | |||
3.2Authorization of Agreements, Etc | 4 | |||
3.3Validity | 5 | |||
3.4Consents | 5 | |||
3.5Subsidiaries | 5 | |||
3.6Capitalization | 5 | |||
3.7Litigation | 5 | |||
3.8Financial Statements | 5 | |||
3.9Taxes | 5 | |||
3.10Intellectual Property | 6 | |||
3.11Brokers | 6 | |||
3.12Insurance | 6 | |||
SECTION 4 REPRESENTATIONS AND WARRANTIES OF PURCHASER | 6 | |||
4.1Experience | 6 | |||
4.2Investment | 6 | |||
4.3Rule 144 | 6 | |||
4.4Access to Data | 7 | |||
4.5Brokers | 7 | |||
4.6Authorization | 7 | |||
SECTION 5 | 7 | |||
5.1“Piggyback” Registration | 7 | |||
5.2Furnish Information | 8 | |||
5.3Sale or Transfer of Shares; Legend | 8 | |||
5.4Indemnification | 10 | |||
5.5Assignment of Registration Rights | 12 | |||
5.6“Market Stand-Off” Agreement | 12 | |||
5.7Termination of Registration Rights | 13 | |||
SECTION 6 PURCHASER’S CONDITIONS TO CLOSING | 13 | |||
6.1Representations and Warranties | 13 | |||
6.2Performance | 13 | |||
6.3Legal Investment | 13 | |||
6.4Proceedings and Documents | 13 | |||
6.5Qualifications | 13 | |||
SECTION 7 COMPANY’S CONDITIONS TO CLOSING | 14 | |||
7.1Representations and Warranties | 14 | |||
7.2Performance | 14 | |||
7.3Legal Investment | 14 |
(i)
Page | ||||
7.4Payment of Purchase Price | 14 | |||
SECTION 8 MISCELLANEOUS | 14 | |||
8.1Governing Law | 14 | |||
8.2Survival | 14 | |||
8.3Successors and Assigns | 14 | |||
8.4Entire Agreement; Amendment and Waiver | 14 | |||
8.5Notices | 15 | |||
8.6Transferability of Shares | 15 | |||
8.7Delays or Omissions | 16 | |||
8.8Severability | 16 | |||
8.9Interpretation | 16 | |||
8.10Information Confidential | 16 | |||
8.11Further Assurances | 16 | |||
8.12Headings | 17 | |||
8.13Counterparts | 17 |
(ii)
Exhibit B-1
Exhibit B-2
Exhibit B-3
Exhibit B-4
Exhibit B-5
Exhibit B-6
Exhibit B-7
Exhibit B-8
Exhibit B-9
Exhibit B-10
Exhibit B-11
Exhibit B-12
Exhibit B-13
Exhibit B-14
Exhibit B-15
If to the Company: | Archemix Corp. | |
300 Third Street | ||
Cambridge, MA | ||
Attn: Chief Executive Officer | ||
Attn: General Counsel | ||
Facsimile: (617) 686-7679 | ||
With a copy to: | Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. | |
One Financial Center | ||
Boston, MA 02111 | ||
Attn: Jeffrey M. Wiesen, Esquire | ||
Facsimile: (617) 542-2241 | ||
If to the Purchaser: | Merck KGaA | |
Legal Department | ||
Frankfurter Str. 250 | ||
64293 Darmstadt | ||
Germany | ||
Facsimile: +49 6151 72 [***] |
Exhibit B-16
Exhibit B-17
Exhibit B-18
COMPANY: | ||||||
ARCHEMIX CORP. | ||||||
By: | ||||||
Name: | ||||||
Title: | ||||||
PURCHASER: | ||||||
Merck KGaA | ||||||
ppa. i.V. | ||||||
[***] |
Exhibit B-19
• | [***] for [***] is [***] or [***] to [***] | ||
• | [***] in [***] with an [***] and an [***]. | ||
• | [***] for the [***] (e.g., no [***] to [[***]]).* | ||
• | [***] to [***] (e.g., to [***] of [***] with an [***], [***]% of [***] in [***] and [***]% of [***]). | ||
• | [***] (e.g., [***] on [***]). | ||
• | [***] as [***] by [***] of [***], a [***] of the [***], or [***] of [***].* | ||
• | [***] can be [***] using [***] with [***]. | ||
• | [***] can be [***] for [***] at [***] and [***] of [***] and with [***] and [***]. | ||
• | [***] for [***] use as [***] using[***]that [***] (e.g., [***]). | ||
• | [***] does not [***] an [***] in the [***] of [***] to [***] other [***]). |
• | [***] | ||
• | [***] of the [***] for its [***] (e.g. [***]) | ||
• | [***] and [***] for [***] | ||
• | [***] |
• | [***] include [***] but not [***]. [***] with [***] provides a [***] for [***] from [***]. | ||
• | The [***] of [***] is [***] by [***] the [***] of [***]. No efforts at [***] are envisioned [***] to [***]. | ||
• | [***] for [***], etc.) have yet to be established. We have [***] any [***] for [***] in these [***] up to [***] of [***]. |
Sched. 1A-1
• | [***] for [***] is [***] or [***]. | ||
• | [***] with an [***]. | ||
• | [***] to [***] on [***] with an [***]. | ||
• | [***] to [***] on [***]. | ||
• | [***]. | ||
• | [***] shows [***] over [***]. | ||
• | [***] is [***] so it can be [***] using [***] with [***], and [***] has been demonstrated without [***] that would [***] risk. | ||
• | [***] of [***]% of [***] remaining following [***] in [***] and [***]% of [***] remaining following [***] in [***]. | ||
• | [***] of [***]% of [***] remaining following [***] in [***] and [***]% of [***] remaining following [***] in [***]. | ||
• | [***] to [***] and [***] of the [***]. | ||
• | [***] at [***] in [***]. | ||
• | [***] has been [***] for [***] at [***] e.g. [***] and [***] (e.g. [***]) [***] without [***] of [***] and with [***] and [***]. | ||
• | [***] of [***] at least [***] for [***] when [***]. | ||
• | [***] as [***] by [***] of [***], a [***] of the [***], or [***] of [***]. | ||
• | [***] for [***] as [***] using[***]that [***] (e.g., [***]). | ||
• | [***] does not [***] an [***] in the [***] of [***] to [***] other [***] and/or [***]). |
• | [***] include [***] but not [***]. [***] with [***] provides a [***] for [***] from [***]. | ||
• | The [***] of [***] is [***] by [***] the [***] of [***]. No efforts at [***] are envisioned [***] to [***]. | ||
• | [***] for [***], etc.) have yet to be established. We have [***] any [***] for [***] in these [***] up to [***] of [***]. |
Sched. 1B-1
• | [***] for [***] is [***] or [***] to [***]. | ||
• | [***] with an [***]. | ||
• | [***] of [***] with an [***]. | ||
• | [***] and [***] with an [***]. | ||
• | [***] is [***] so it can be [***] using [***] with [***], and [***] has been demonstrated without [***] that would [***]. | ||
• | [***]) of [***]% of [***] remaining following [***] in [***] and/or [***] and [***]% of [***] remaining following [***] in [***]. | ||
• | [***] to [***] of the [***]. | ||
• | [***] at [***] in [***]. | ||
• | [***] has been [***] for [***] at [***] e.g. [***] and [***] (e.g. [***]) [***] without [***] of [***] and with [***] and [***]. | ||
• | [***] at [***] for [***] when [***] and/or [***]. | ||
• | [***] for the [***] (e.g., no [***] to [[***]]). | ||
• | [***] as [***] by [***], a [***] of the [***], or [***] of [***]. | ||
• | [***] for [***] as [***] using[***]that [***] (e.g., [***]). | ||
• | [***] does not [***] an [***] in the [***] of [***] to [***] other [***] (typically restricted to [***] and/or [***]). |
Sched. 1B-2
• | [***] include [***] but not [***]. [***] with [***] provides a [***] for [***] from [***]. | ||
• | The [***] of [***] is [***] by [***] the [***] of [***]. No efforts at [***] are envisioned [***]. | ||
• | [***] for [***], etc.) have yet to be established. We have [***] any [***] for [***] in these [***] up to [***] of [***]. |
Sched. 1B-3
Sched. 2A-1
• | [***] | |
• | [***] |
Sched. 2B-1
Sched. 3-1
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
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Sched. 3-2
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Sched. 3-3
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Sched. 3-4
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Sched. 3-5
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[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
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[***] | [***] | [***] | [***] | [***] | [***] | |||||
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Sched. 3-6
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[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] |
Sched. 3-7
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] |
Sched. 3-8
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | |||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | |||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] |
Sched. 3-9
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] |
Sched. 3-10
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] |
Sched. 3-11
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] |
Sched. 3-12
[***] | [***] | [***] | [***] | [***] | [***] | |||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] | ||||||
[***] | [***] | [***] | [***] | [***] |
Sched. 3-13
• | [***] | |
• | [***] | |
• | [***] |
Sched. 4-1
• | [***] from [***] and [***] of [***] and [***] in [***] (e.g., [***] (or [***]) by a [***]). | ||
• | [***] of[***]with [***] or [***] of [***] with [***] to [***] of [***] in [***] and [***] with the [***]. | ||
• | [***] in [***] appears [***] for the [***]. | ||
• | [***] and [***]. | ||
• | [***] (incl. [***]) | ||
• | [***] with [***], as defined [***] the [***] (thus [***]) |
o | [***] remain [***] than a [***] (as measured by [***]) [***] the [***] (e.g., after [***]). |
• | (If [***] requires [***]) |
o | [***] after [***] in [***], with [***] to [***]. | ||
o | With [***] in [***], no [***] of [***] in [***] of [***] the [***] (e.g., after [***]) which would result in a [***] in the [***] to [***] of [***]. |
• | (If [***] requires [***]) |
o | [***] of [***] in [***]. | ||
o | [***] and [***] must permit a [***] that can [***] be [***] though a [***] or [***]. | ||
o | [***] at [***] in [***] at [***] and [***]. |
Sched. 5A-1
• | [***] from [***] and [***] of [***] and [***] in [***] (e.g., [***] (or [***]) by a [***]). | |
• | [***] of[***]with [***] or [***] of [***] with [***] to [***] of [***] in [***] and [***] with the [***]. | |
• | [***] in [***] appears [***] for the [***]. | |
• | [***] and [***]. | |
• | [***] | |
• | [***] with [***], as defined [***] the [***] (thus no [***]) |
o | [***] remain [***] than a [***] (as measured by [***]) [***] the [***] (e.g., after [***]). |
• | (If [***] requires [***]) |
o | [***] after [***] in [***], with [***] to [***]. | ||
o | With [***] in [***], no [***] of [***] in [***] of [***] the [***] (e.g., after [***]) which would result in a [***] in the [***] to [***] of [***]. |
• | (If [***]) |
o | [***] of [***] | ||
o | [***] and [***] must permit a [***] that can [***] be [***] though a [***] or [***]. | ||
o | [***] at [***] in [***] at [***] and [***]. |
Sched. 5B-1
Sched. 6-1
For Archemix:
Kathryn Morris
Yates and Associates
Tel: 914-204-6412
Lilian Stern
Stern Investor Relations
Tel: 212-362-1200
Sched. 6-2
Sched. 6-3
![(MERCK LOGO)](https://capedge.com/proxy/S-1A/0000950135-07-004782/b65464a1b6546401.gif)
Your Contact | ||
News Release | Phyllis Carter | |
Phone +49 6151-72 7144 |
Sched. 6-4
Sched. 6-5
PATENT APPLICATIONS ARE TO BE NATIONALIZED
OR OTHERWISE PROSECUTED, FILED AND MAINTAINED
[***]* (PCT)
[***] (PCT)
[***] (PCT)
[***] (PCT)
[***] (PCT)
[***] (PCT)
[***] (PCT)
[***] (PCT)
[***] (PCT)
[***] (national)
[***] (PCT)
[***] (PCT)
[***] (PCT)
[***] (PCT)
[***] (national via extension)
Sched. 7-1
FORM OF CO-PROMOTION AGREEMENT
• | ARCHEMIX and MERCK shall [***], at ARCHEMIX’s [***]ARCHEMIX and MERCK [***] MERCK, which shall be[***] of the [***] shall be [***] as set forth in the [***]. In the [***] on a [***] by the [***], then [***] of an ARCHEMIX [***], and [***]ARCHEMIX [***], the [***] shall be [***] to the [***], but if the [***]MERCK shall [***], but shall only [***] of the [***]. | ||
• | A [***] shall be [***] by MERCK for [***] [***] for the [***] for [***] by the [***] which shall [***], but not be [***] of such [***] in the [***] to be [***] of any[***] of the [***] of such [***] at least [***] and [***] for such [***]in the [***] for such [***]in the [***]. | ||
• | [***] of both MERCK and ARCHEMIX. For the ARCHEMIX [***] on the [***]. For the [***] of the [***], provided that the [***] of MERCK [***]. | ||
• | Each [***] that ARCHEMIX [***] of the [***] of the [***] for the [***] in the [***] of the [***] in the [***]. The [***] shall be [***]shall be [***]. | ||
• | Each [***] under each [***] and to [***] with the other [***]. The [***] that the [***] the [***] (which [***], and a [***] that shall be [***] for purposes of the [***]. | ||
• | Each [***] for a [***]. Each [***] shall have the r[***] of the [***]. | ||
• | MERCK shall [***] and for [***] as may be [***] and other [***], but shall, in [***]. | ||
• | MERCK shall [***] for the [***]. | ||
• | MERCK shall [***]. | ||
• | MERCK shall [***] for the [***]. | ||
• | MERCK shall [***] under which [***]. The [***] in the [***] under such [***]. | ||
• | [***]MERCK. |
Sched. 8-1
• | [***] shall be [***] with the [***]. | ||
• | The [***]with [***]. With regard to any [***] by a [***] to the [***] and to [***] that, to the [***] of the [***]. |
Sched. 8-2
APPLIED IN ITS EXTERNAL REPORTING
Sched. 9-1
[***]: [***] containing [***], or [***] of [***]. | ||
[***]: |
[***]
[***]
[***]
[***]
[***]
Sched. 10-1
Sched. 11-1
Sched. 12-1
(a) | was already known to Merck at the time of disclosure as evidenced by competent business records of Merck; | ||
(b) | was generally available to the public or otherwise part of the public domain at the time of its disclosure; | ||
(c) | became generally available to the public or otherwise part of the public domain after its disclosure to Merck through no act or omission of Merck; | ||
(d) | was disclosed to Merck by a third party who had no obligation to Archemix not to disclose such information; | ||
(e) | was independently developed by Merck without the use of the Archemix’s Confidential Information as evidenced by competent business records of Merck. |
Sched. 12-2
Sched. 12-3
ARCHEMIX CORP. | ||||
By: | ||||
Name: | ||||
Title: | ||||
Date: | ||||
MERCK KGaA | ||||
By: | ||||
Name: | ||||
Title: | ||||
Date: | ||||
Sched. 12-4
(AND [***] FOR THEIR [***])
AND CO-DEVELOPMENT REGULATORY COSTS
1 | Definitions. | |
Words and phrases used in this Schedule shall have the meanings defined elsewhere in the Agreement. In addition, the following words and phrases shall have the following stated or referenced meanings in this Schedule: | ||
[***]1.2“Co-Development Costs” means [***] to [***] for a [***] in the [***] for a [***] shall [***]and [***], of the [***]: |
(a) | [***] and other [***] ; | ||
(b) | [***] and [***]; | ||
(c) | [***] and [***] for use in [***]; | ||
(d) | [***] and [***], and other [***] with the [***]; | ||
(e) | [***]; and | ||
(f) | [***] to [***] in the [***]. |
“Co-Development FTE”shall mean [***] of [***] to or in [***] with respect to a [***] that are [***], with [***] in effect at the [***]“ARCHEMIX Co-Development FTE Rate(s)”means, [***] to a [***] at the [***] for such [***]for [***] at such [***], that, on [***]of each [***] for such [***], the [***] shall be [***] in the [***]. For [***] of this [***] of this [***] is as [***] to[***] and/or [***]. | ||
“MERCK Co-Development FTE Rate(s)”means, [***] to a [***] at the [***] provided, that, on [***] of each [***] of its [***], the [***] shall be [***]in the [***]. For purposes of this [***] of this [***]. | ||
“Co-Development FTE Rate(s)”means, [***]. For [***] to the [***]. | ||
“Co-DevelopmentFTE Cost”means, [***] in such [***] to be [***] by the [***], at the [***]. | ||
1.3 | “External Co-Development Costs” means the [***] by a [***] or to be [***]. | |
1.4 | “Internal Co-Development Costs” means the [***] by [***]. For purposes of [***]. | |
1.5 | “Co-Development Regulatory Costs” means [***] that are [***]with the [***] to the [***], and the [***], for any [***] for a [***] shall [***], of the [***]: |
(a) | [***] for the [***]; | ||
(b) | [***] or other [***]; and |
Sched. 13-1
Sched. 13-2