Exhibit 31.1
CERTIFICATION
I, John A. Orwin, certify that:
1. I have reviewed this Form 10-Q/A of Affymax, Inc.; and
2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.
| By: | /s/ JOHN A. ORWIN |
|
| Chief Executive Officer and Member of the Board of Directors |
Date: November 9, 2012 |
| (Principal Executive Officer) |
