Standard BioTools (LAB) S-3 Shelf registration

Exhibit 12.1

COMPUTATION OF RATIO OF EARNINGS TO COMBINED FIXED CHARGES AND PREFERENCE DIVIDENDS

	Fiscal Year Ended
(In thousands)	December 29, 2007		December 27, 2008		December 31, 2009		December 31, 2010		December 31, 2011
Earnings:
Net loss before income taxes		(25,346)		(29,646)		(19,178)		(16,819)		(22,304)
Add: Combined fixed charges		3,448		2,562		3,761		2,908		3,621
Less: Capitalized interest		-		-		-		-		-
Total earnings for computation of ratio		(21,898)		(27,084)		(15,417)		(13,911)		(18,683)
Fixed Charges:
Interest expense including capitalized interest		2,790		2,031		2,876		2,158		3,101
Estimated interest component of rent		658		531		885		750		520
Total fixed charges		3,448		2,562		3,761		2,908		3,621
Combined fixed charges and preference dividends:
Interest expense including capitalized interest		2,790		2,031		2,876		2,158		3,101
Estimated interest component of rent		658		531		885		750		520
Deemed dividend		-		-		-		-		9,900
Total combined fixed charges and preference dividends		3,448		2,562		3,761		2,908		13,521
Ratio of earnings to fixed charges (1)		-		-		-		-		-
Ratio of earnings to combined fixed charges and preference dividends (1)		-		-		-		-		-

(1) Earnings for 2007, 2008, 2009, 2010, and 2011 were insufficient to cover fixed charges and preference dividends by $25.3 million, $29.6 million, $19.2 million, $16.8 million and $32.2 million, respectively. As of the date of this prospectus, we have no shares of preferred stock outstanding and, consequently, our ratio of earnings to combined fixed charges and preference dividends and ratio of earnings to fixed charges would be identical.