Exhibit 16.1 Letter from Rubin Brown LLP pursuant to Item 304(a)(3) of Regulation S-B.
RubinBrown
Rubin Brown LLP
Certified Public Accountants
& Business Consultants
One North Brentwood
St. Louis, Missouri 63105
T 314.290.3300
F 314.290.3400
W rubinbrown.com
E infor@rubinbrown.com
August 18, 2005
United States Securities & Exchange Commission
Division of Corporate Finance
450 Fifth Street, N.W.
Washington, D.C. 20549
Gentlemen:
We have read the following paragraphs of Item 4.01 included in the Form 8-K/A
filed on August 18, 2005 of GenoMed, Inc. and we are in agreement with the
statements contained in these paragraphs:
o (a)(1) (i) and (ii)
o (a)(1) (iv) (A)
o (a)(3)
We have no basis to agree or disagree with Item 4.01, paragraphs (a)(1)(iii) and
(a)(2).
Very truly yours,
/s/ Rubin Brown LLP
Rubin Brown LLP