| Cover | May 17, 2022 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | May 17, 2022 |
| Entity File Number | 001-32188 |
| Entity Registrant Name | Oragenics, Inc. |
| Entity Central Index Key | 0001174940 |
| Entity Tax Identification Number | 59-3410522 |
| Entity Incorporation, State or Country Code | FL |
| Entity Address, Address Line One | 4902 Eisenhower Boulevard |
| Entity Address, Address Line Two | Suite 125 |
| Entity Address, City or Town | Tampa |
| Entity Address, State or Province | FL |
| Entity Address, Postal Zip Code | 33634 |
| City Area Code | 813 |
| Local Phone Number | 286-7900 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common Stock |
| Trading Symbol | OGEN |
| Security Exchange Name | NYSEAMER |
| Entity Emerging Growth Company | false |
