Income Taxes | 11. Income Taxes The components of the provision for income taxes for the years ended December 31, 2023 and 2022 are as follows: Schedule of Components of Provision for Income Taxes 2023 2022 Current $ — $ — Deferred (5,791,558 ) (3,714,988 ) Valuation Allowance 5,791,558 3,714,988 Total provision (Deferred benefit) for income taxes $ — $ — At December 31, 2023 and 2022, the Company had temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and their respective income tax bases, as measured by enacted state and federal tax rates, as follows: Summary of Components of Deferred Tax 2023 2022 Deferred tax assets (liabilities): Net operating loss carryforward $ 39,810,409 $ 37,713,107 Accrued vacation - 8,751 Non-qualified stock compensation 1,160,775 1,119,642 Capitalized Research & Development costs 3,417,706 2,325,391 Intangibles 2,569,559 - Total deferred tax assets 46,958,449 41,166,891 Less valuation allowance (46,958,449 ) (41,166,891 ) Total net deferred tax asset, net of valuation allowance $ — $ — The following is a reconciliation of tax computed at the statutory federal rate to the income tax expense (benefit) in the statements of operations for the years ended December 31, 2023 and 2022: Schedule of Reconciliation of Tax Computed at Statutory Federal Rate 2023 2022 Income tax benefit computed at statutory federal rate of 21 21 $ (4,337,705 ) $ (3,000,564 ) State income tax benefits, net of federal expense/benefit (1,204,720 ) (785,862 ) Prior year adjustment 150,533 - Change in valuation allowance 5,342,529 3,714,988 Non-deductible expenses 272 612 Other 49,091 70,826 Total provision (benefit) for income taxes $ — $ — In assessing the realizability of deferred tax assets, management considers whether it is more likely than not that some portion or all of the deferred tax assets will not be realized. The ultimate realization of deferred tax assets is dependent upon the generation of future taxable income during the periods in which those temporary differences become deductible. Management considers the scheduled reversal of deferred tax liabilities, projected future taxable income, and tax planning strategies in making this assessment. Based upon the levels of historical taxable income and projections of future taxable income over which the deferred tax assets are deductible, the Company believes that it is more likely than not that it will not be able to realize the benefits of these deductible differences. Accordingly, a valuation allowance of $ 46,958,449 and $ 41,166,891 has been provided in the accompanying consolidated financial statements as of December 31, 2023 and 2022, respectively. The December 31, 2023 and December 31, 2022 net change in valuation allowance related to deferred tax assets was an increase of $ 5,791,558 and $ 3,714,988 At December 31, 2023, the Company has federal and state tax net operating loss carryforwards of $ 153,575,836 137,731,183 The State of Pennsylvania tax net operating loss carryforwards will expire through 2036. Federal and Florida tax net operating loss carryforwards generated prior to December 31, 2017 will expire through 2037 and are not subject to taxable income limitations. Federal and Florida tax net operating loss carryforwards generated subsequent to December 31, 2017, do not expire but may be subject to taxable income limitation pursuant to the Tax Cuts and Jobs Act that was enacted on December 22, 2017. The Company also has federal research and development tax credit carryforwards of $ 4,169,354 . The federal tax credit carryforward will expire beginning in 2021 and continuing through 2043 unless utilized. Utilization of net operating loss carryforwards and research and development credit carryforwards may be subject to a substantial annual limitation due to ownership change limitations that may have occurred or, could occur in the future in accordance with Section 382 of the Internal Revenue Code of 1986 (“IRC Section 382”) and with Section 383 of the Internal Revenue Code of 1986, as well as similar state provisions. These ownership changes may limit the amount of net operating loss carryforwards and research and development credit carryforwards that can be utilized annually to offset future taxable income and taxes, respectively. In general, an ownership change, as defined by IRC Section 382, results from transactions increasing the ownership of certain stockholders or public groups in the stock of a corporation by more than 50 percentage points over a three-year period. The Company has completed several financings since its inception which may result in a change in ownership as defined by IRC Section 382 or could result in a change in control in the future. For the years ended December 31, 2023 and 2022, the Company incurred $ 46,229 940,106 The Company files its income tax returns in the U.S. federal jurisdiction and in Florida and Pennsylvania. With few exceptions, the Company is no longer subject to federal or state income tax examinations by tax authorities for years before 201. A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows: Schedule of Reconciliation of Unrecognized Tax Benefits Balance as of December 31, 2021 $ 4,027,180 Additions based on tax positions related to the current year 940,106 Reductions for the tax positions of prior years (115,396 ) Expired Tax Credits due to 20-year life (17,043 ) Balance as of December 31, 2022 $ 4,834,847 Additions based on tax positions related to the current 46,229 Reductions for the tax positions of prior years (680,042 ) Expired Tax Credits due to 20-year life (31,680 ) Balance as of December 31, 2023 $ 4,169,354 Included in the balance at December 31, 2023 and 2022, are $ 4,169,354 4,834,847 During the years 2023 and 2022 the Company did not recognize any interest and penalties. Due to the potential offset of the Company’s operating loss carryforward for any future activity, the amount attributed to interest and penalties would be immaterial. |