| Document and Entity Information | Mar. 29, 2022 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | Mar. 29, 2022 |
| Entity Registrant Name | SCYNEXIS, Inc. |
| Entity Central Index Key | 0001178253 |
| Entity Emerging Growth Company | false |
| Entity File Number | 001-36365 |
| Entity Incorporation, State or Country Code | DE |
| Entity Tax Identification Number | 56-2181648 |
| Entity Address, Address Line One | 1 Evertrust Plaza |
| Entity Address, Address Line Two | 13th Floor |
| Entity Address, City or Town | Jersey City |
| Entity Address, State or Province | NJ |
| Entity Address, Postal Zip Code | 07302-6548 |
| City Area Code | 201 |
| Local Phone Number | 884-5485 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common Stock, par value $0.001 |
| Trading Symbol | SCYX |
| Security Exchange Name | NASDAQ |
