Pay vs Performance Disclosure - USD ($) | 5 Months Ended | 7 Months Ended | 12 Months Ended |
Dec. 31, 2022 | Jul. 31, 2022 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020 |
Pay vs Performance Disclosure [Table] | | | | | |
Pay vs Performance [Table Text Block] | | | Pay Versus Performance This disclosure has been prepared in accordance with the SEC’s pay versus performance rules in Item 402(v) of Regulation S-K under the 1934 Act (“Item 402(v)”) and does not necessarily reflect value actually realized by the Named Executive Officers or how the Compensation and Leadership Development Committee evaluates compensation decisions in light of Company or individual performance. For discussion of how the Compensation and Leadership Development Committee seeks to align pay with performance when making compensation decisions, please review the Compensation Discussion and Analysis beginning on page 25 The following tables and related disclosures provide information about (i) the total compensation (“SCT Total”) of our principal executive officer (“PEO”) and our non-PEO named executive officers (collectively, the “Other NEOs”) as presented in the Summary Compensation Table on page 42 Year (a) Summary Compen- sation Table Total for PEO: John F. Crowley ($) (b) Summary Compen- sation Table Total for PEO: Bradley L. Campbell ($) (b) Compen- sation Actually Paid to PEO: John F. Crowley ($) (c) Compen- sation Actually Paid to PEO: Bradley L. Campbell ($) (c) Average Summary Compen- sation Table Total for non-PEO Named Executive Officers ($) (d) Average Compen- sation Actually Paid to non-PEO Named Executive Officers ($) (e) Value of Initial Fixed $100 Investment on Dec. 31, 2019 Based on Net Income ($) (thous- ands) (h) Net Product Sales ($) (thous- ands) (i) Total Share- holder Return (f) Peer Group Total Share- holder Return (g) 2022 $10,001,131 $8,997,866 10,806,940 $9,556,649 $3,270,640 $ 3,208,762 $122 $ 110 $(236,568) $329,233 2021 9,990,032 — (13,481,915) — 3,307,641 (3,681,239) 119 125 (250,460) 305,514 2020 11,315,124 — 37,594,876 — 3,232,985 8,997,906 237 126 (276,852) 260,886 Names of PEO and Other NEOs (Column (b); Column (c); Column (d); Column (e)) 2022: PEOs: John F. Crowley served as our PEO through August 1, 2022 and Bradley L. Campbell became our PEO effective August 1, 2022; Other NEOs: Daphne Quimi, Ellen S. Rosenberg, David M. Clark, and Jeffrey P. Castelli. 2021: PEO: John F. Crowley; Other NEOs: Bradley L. Campbell, Daphne Quimi, Ellen S. Rosenberg, David M. Clark, and Hung Do. 2020: PEO: John F. Crowley; Other NEOs: Bradley L. Campbell, Daphne Quimi, Ellen S. Rosenberg, Hung Do, and Jay Barth. Adjustments to Calculate Compensation Actually Paid to PEO (Column (c)) and Average Compensation Actually Paid to Other NEOs (Column (e)) The table below describes the adjustments, each of which is required by SEC rules, to calculate CAP Amounts from the SCT Total of our PEO(s) (Columns (b) and (c)) and our Other NEOs (Column (d)). The SCT Total and CAP Amounts do not reflect the actual amount of compensation earned by or paid to our executives during the applicable years, but rather are amounts determined in accordance with Item 402(v). 2022 2021 2020 Adjustments PEO: John F. Crowley PEO: Bradley L. Campbell Other NEOs* PEO Other NEOs* PEO Other NEOs* SCT Totals $10,001,131 $ 8,997,866 $ 3,270,640 $ 9,990,032 $ 3,307,641 $ 11,315,124 $ 3,232,985 Adjustments for stock awards and option awards (Deduct): Aggregate value for stock awards and option awards included in SCT Total for the covered fiscal year (8,122,327) (8,013,779) (2,540,515) (7,927,324) (2,536,712) (7,972,462) (2,444,876) Add: Fair value at year end of awards granted during the covered fiscal year that were outstanding and unvested at the covered fiscal year end 9,660,582 8,908,774 2,670,154 3,494,888 1,127,092 20,957,289 5,365,039 2022 2021 2020 Adjustments PEO: John F. Crowley PEO: Bradley L. Campbell Other NEOs* PEO Other NEOs* PEO Other NEOs* Add (Deduct): Year-over-year change in fair value at covered fiscal year end of awards granted in any prior fiscal year that were outstanding and unvested at the covered fiscal year end 391,911 188,427 107,386 (11,768,843) (3,516,814) 11,187,359 2,592,973 Add: Vesting date fair value of awards granted and vested during the covered fiscal year — — — — — — 12,278 (Deduct) Add: Change as of the vesting date (from the end of the prior fiscal year) in fair value of awards granted in any prior fiscal year for which vesting conditions were satisfied during the covered fiscal year 357,923 167,091 86,488 (5,922,905) (1,712,039) 2,367,147 502,296 (Deduct): Fair value at end of prior fiscal year of awards granted in any prior fiscal year that failed to meet the applicable vesting conditions during the covered fiscal year (1,482,280) (691,730) (385,391) (1,347,763) (350,407) (259,581) (262,789) CAP Amounts (as calculated) $10,806,940 $9,556,649 $3,208,762 ($ 13,481,915) ($ 3,681,239) $37,594,876 $8,997,906 * Amounts presented are averages for the entire group of non-PEO NEOs in each respective year Total Shareholder Return (Column (f); Column (g)) The share prices illustrate the cumulative total shareholder return (“TSR”) each year of Amicus common stock and of the Nasdaq Biotechnology Index (the “Peer Group”) since December 31, 2019, of a $100 investment. All values assume reinvestment of the full amount of all dividends, however no dividends have been declared on our common stock to date. The Peer Group used in this disclosure is the same Peer Group used in Part II, Item 5 of our Form 10-K. Net Income (Column (h)) Reported in the Company’s Consolidated Statements of Operations included in our Form 10-K as “Net Loss,” which is how we’ve referred o this performance measure in the graphs that follow. Net Product Sales (Column (i)) Net product sales as reported in the Company’s Consolidated Statements of Operations included in our Form 10-K. Net product sales was determined to be the most important financial performance measure linking CAP to Company performance for 2022 and therefore was selected as the 2022 “Company-Selected Measure” as defined in Item 402(v). | | |
Company Selected Measure Name | | | Net Product Sales | | |
Named Executive Officers, Footnote [Text Block] | | | Names of PEO and Other NEOs (Column (b); Column (c); Column (d); Column (e)) 2022: PEOs: John F. Crowley served as our PEO through August 1, 2022 and Bradley L. Campbell became our PEO effective August 1, 2022; Other NEOs: Daphne Quimi, Ellen S. Rosenberg, David M. Clark, and Jeffrey P. Castelli. 2021: PEO: John F. Crowley; Other NEOs: Bradley L. Campbell, Daphne Quimi, Ellen S. Rosenberg, David M. Clark, and Hung Do. 2020: PEO: John F. Crowley; Other NEOs: Bradley L. Campbell, Daphne Quimi, Ellen S. Rosenberg, Hung Do, and Jay Barth. | | |
Peer Group Issuers, Footnote [Text Block] | | | Total Shareholder Return (Column (f); Column (g)) The share prices illustrate the cumulative total shareholder return (“TSR”) each year of Amicus common stock and of the Nasdaq Biotechnology Index (the “Peer Group”) since December 31, 2019, of a $100 investment. All values assume reinvestment of the full amount of all dividends, however no dividends have been declared on our common stock to date. The Peer Group used in this disclosure is the same Peer Group used in Part II, Item 5 of our Form 10-K. | | |
Adjustment To PEO Compensation, Footnote [Text Block] | | | Adjustments to Calculate Compensation Actually Paid to PEO (Column (c)) and Average Compensation Actually Paid to Other NEOs (Column (e)) The table below describes the adjustments, each of which is required by SEC rules, to calculate CAP Amounts from the SCT Total of our PEO(s) (Columns (b) and (c)) and our Other NEOs (Column (d)). The SCT Total and CAP Amounts do not reflect the actual amount of compensation earned by or paid to our executives during the applicable years, but rather are amounts determined in accordance with Item 402(v). 2022 2021 2020 Adjustments PEO: John F. Crowley PEO: Bradley L. Campbell Other NEOs* PEO Other NEOs* PEO Other NEOs* SCT Totals $10,001,131 $ 8,997,866 $ 3,270,640 $ 9,990,032 $ 3,307,641 $ 11,315,124 $ 3,232,985 Adjustments for stock awards and option awards (Deduct): Aggregate value for stock awards and option awards included in SCT Total for the covered fiscal year (8,122,327) (8,013,779) (2,540,515) (7,927,324) (2,536,712) (7,972,462) (2,444,876) Add: Fair value at year end of awards granted during the covered fiscal year that were outstanding and unvested at the covered fiscal year end 9,660,582 8,908,774 2,670,154 3,494,888 1,127,092 20,957,289 5,365,039 2022 2021 2020 Adjustments PEO: John F. Crowley PEO: Bradley L. Campbell Other NEOs* PEO Other NEOs* PEO Other NEOs* Add (Deduct): Year-over-year change in fair value at covered fiscal year end of awards granted in any prior fiscal year that were outstanding and unvested at the covered fiscal year end 391,911 188,427 107,386 (11,768,843) (3,516,814) 11,187,359 2,592,973 Add: Vesting date fair value of awards granted and vested during the covered fiscal year — — — — — — 12,278 (Deduct) Add: Change as of the vesting date (from the end of the prior fiscal year) in fair value of awards granted in any prior fiscal year for which vesting conditions were satisfied during the covered fiscal year 357,923 167,091 86,488 (5,922,905) (1,712,039) 2,367,147 502,296 (Deduct): Fair value at end of prior fiscal year of awards granted in any prior fiscal year that failed to meet the applicable vesting conditions during the covered fiscal year (1,482,280) (691,730) (385,391) (1,347,763) (350,407) (259,581) (262,789) CAP Amounts (as calculated) $10,806,940 $9,556,649 $3,208,762 ($ 13,481,915) ($ 3,681,239) $37,594,876 $8,997,906 * Amounts presented are averages for the entire group of non-PEO NEOs in each respective year | | |
Non-PEO NEO Average Total Compensation Amount | | | $ 3,270,640 | $ 3,307,641 | $ 3,232,985 |
Non-PEO NEO Average Compensation Actually Paid Amount | | | $ 3,208,762 | (3,681,239) | 8,997,906 |
Adjustment to Non-PEO NEO Compensation Footnote [Text Block] | | | Adjustments to Calculate Compensation Actually Paid to PEO (Column (c)) and Average Compensation Actually Paid to Other NEOs (Column (e)) The table below describes the adjustments, each of which is required by SEC rules, to calculate CAP Amounts from the SCT Total of our PEO(s) (Columns (b) and (c)) and our Other NEOs (Column (d)). The SCT Total and CAP Amounts do not reflect the actual amount of compensation earned by or paid to our executives during the applicable years, but rather are amounts determined in accordance with Item 402(v). 2022 2021 2020 Adjustments PEO: John F. Crowley PEO: Bradley L. Campbell Other NEOs* PEO Other NEOs* PEO Other NEOs* SCT Totals $10,001,131 $ 8,997,866 $ 3,270,640 $ 9,990,032 $ 3,307,641 $ 11,315,124 $ 3,232,985 Adjustments for stock awards and option awards (Deduct): Aggregate value for stock awards and option awards included in SCT Total for the covered fiscal year (8,122,327) (8,013,779) (2,540,515) (7,927,324) (2,536,712) (7,972,462) (2,444,876) Add: Fair value at year end of awards granted during the covered fiscal year that were outstanding and unvested at the covered fiscal year end 9,660,582 8,908,774 2,670,154 3,494,888 1,127,092 20,957,289 5,365,039 2022 2021 2020 Adjustments PEO: John F. Crowley PEO: Bradley L. Campbell Other NEOs* PEO Other NEOs* PEO Other NEOs* Add (Deduct): Year-over-year change in fair value at covered fiscal year end of awards granted in any prior fiscal year that were outstanding and unvested at the covered fiscal year end 391,911 188,427 107,386 (11,768,843) (3,516,814) 11,187,359 2,592,973 Add: Vesting date fair value of awards granted and vested during the covered fiscal year — — — — — — 12,278 (Deduct) Add: Change as of the vesting date (from the end of the prior fiscal year) in fair value of awards granted in any prior fiscal year for which vesting conditions were satisfied during the covered fiscal year 357,923 167,091 86,488 (5,922,905) (1,712,039) 2,367,147 502,296 (Deduct): Fair value at end of prior fiscal year of awards granted in any prior fiscal year that failed to meet the applicable vesting conditions during the covered fiscal year (1,482,280) (691,730) (385,391) (1,347,763) (350,407) (259,581) (262,789) CAP Amounts (as calculated) $10,806,940 $9,556,649 $3,208,762 ($ 13,481,915) ($ 3,681,239) $37,594,876 $8,997,906 * Amounts presented are averages for the entire group of non-PEO NEOs in each respective year | | |
Compensation Actually Paid vs. Total Shareholder Return [Text Block] | | | Relationship Between Compensation Actually Paid and Performance The graphs below show the relationship of “compensation actually paid” to our PEO and Other NEOs to (i) the Company’s net product sales growth and net loss and (ii) TSR of both the Company and the Nasdaq Biotechnology Index. CAP, as calculated in accordance with Item 402(v), reflects, among others, adjustments to the fair value of equity awards during the years presented. In light of the significant weighting of long-term stock-based incentives in our pay mix (which approximates a range of 79%-89% for our PEOs and 74%-78% for our Other NEOs, of total compensation) due to the intended alignment between our executives and stockholders, the CAP values are significantly influenced by the value of our stock price. CAP in 2021 reflects a significant decrease in the value of prior year awards and awards granted in 2021 compared to their grant date. Conversely, CAP in 2022 reflects a modest increase in the value of prior year awards and awards granted in 2022 compared to their grant date offset by prior year performance-based awards that failed to meet applicable vesting conditions. | | |
Compensation Actually Paid vs. Net Income [Text Block] | | | Relationship Between Compensation Actually Paid and Performance The graphs below show the relationship of “compensation actually paid” to our PEO and Other NEOs to (i) the Company’s net product sales growth and net loss and (ii) TSR of both the Company and the Nasdaq Biotechnology Index. | | |
Compensation Actually Paid vs. Company Selected Measure [Text Block] | | | Relationship Between Compensation Actually Paid and Performance The graphs below show the relationship of “compensation actually paid” to our PEO and Other NEOs to (i) the Company’s net product sales growth and net loss and (ii) TSR of both the Company and the Nasdaq Biotechnology Index. | | |
Total Shareholder Return Vs Peer Group [Text Block] | | | Relationship Between Compensation Actually Paid and Performance The graphs below show the relationship of “compensation actually paid” to our PEO and Other NEOs to (i) the Company’s net product sales growth and net loss and (ii) TSR of both the Company and the Nasdaq Biotechnology Index. CAP, as calculated in accordance with Item 402(v), reflects, among others, adjustments to the fair value of equity awards during the years presented. In light of the significant weighting of long-term stock-based incentives in our pay mix (which approximates a range of 79%-89% for our PEOs and 74%-78% for our Other NEOs, of total compensation) due to the intended alignment between our executives and stockholders, the CAP values are significantly influenced by the value of our stock price. CAP in 2021 reflects a significant decrease in the value of prior year awards and awards granted in 2021 compared to their grant date. Conversely, CAP in 2022 reflects a modest increase in the value of prior year awards and awards granted in 2022 compared to their grant date offset by prior year performance-based awards that failed to meet applicable vesting conditions. | | |
Tabular List [Table Text Block] | | | Financial Performance Measures The following table lists the financial performance measures that, in the Company’s assessment, represent the most important performance measures used to link CAP for our Named Executive Officers to Company performance for 2022. Net Product Sales (Company-Selected Measure) Relative Total Shareholder Return (TSR) Non-GAAP Operating Expenses | | |
Total Shareholder Return Amount | | | $ 122 | 119 | 237 |
Peer Group Total Shareholder Return Amount | | | 110 | 125 | 126 |
Net Income (Loss) | | | $ (236,568,000) | $ (250,460,000) | $ (276,852,000) |
Company Selected Measure Amount | | | 329,233,000 | 305,514,000 | 260,886,000 |
PEO Name | Bradley L. Campbell | John F. Crowley | | John F. Crowley | John F. Crowley |
Measure [Axis]: 1 | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Measure Name | | | Net Product Sales (Company-Selected Measure) | | |
Measure [Axis]: 2 | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Measure Name | | | Relative Total Shareholder Return (TSR) | | |
Measure [Axis]: 3 | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Measure Name | | | Non-GAAP Operating Expenses | | |
John F. Crowley [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
PEO Total Compensation Amount | | | $ 10,001,131 | $ 9,990,032 | $ 11,315,124 |
PEO Actually Paid Compensation Amount | | | 10,806,940 | (13,481,915) | 37,594,876 |
Bradley L. Campbell [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
PEO Total Compensation Amount | | | 8,997,866 | 0 | 0 |
PEO Actually Paid Compensation Amount | | | 9,556,649 | 0 | 0 |
PEO [Member] | John F. Crowley [Member] | Aggregate Value for Stock Awards and Option Awards included in SCT Total for Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | (8,122,327) | (7,927,324) | (7,972,462) |
PEO [Member] | John F. Crowley [Member] | Fair Value at Year End of Awards Granted During Covered Fiscal Year Outstanding and Unvested at the Covered Fiscal Year End [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 9,660,582 | 3,494,888 | 20,957,289 |
PEO [Member] | John F. Crowley [Member] | Year Over Year Change in Fair Value at Covered Fiscal Year End of Awards Granted in Any Prior Fiscal Year Outstanding and Unvested at the Covered Fiscal Year End [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 391,911 | (11,768,843) | 11,187,359 |
PEO [Member] | John F. Crowley [Member] | Vesting Date Fair Value of Awards Granted and Vested During the Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 0 | 0 | 0 |
PEO [Member] | John F. Crowley [Member] | Change Vesting Date From the End of the Prior Fiscal Year in Fair Value of Awards Granted in Any Prior Fiscal Year for Which Vesting Conditions Satisfied During the Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 357,923 | (5,922,905) | 2,367,147 |
PEO [Member] | John F. Crowley [Member] | Fair Value at End of Prior Fiscal Year of Awards Granted in Any Prior Fiscal Year that Failed to Meet the Applicable Vesting Conditions During the Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | (1,482,280) | (1,347,763) | (259,581) |
PEO [Member] | Bradley L. Campbell [Member] | Aggregate Value for Stock Awards and Option Awards included in SCT Total for Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | (8,013,779) | | |
PEO [Member] | Bradley L. Campbell [Member] | Fair Value at Year End of Awards Granted During Covered Fiscal Year Outstanding and Unvested at the Covered Fiscal Year End [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 8,908,774 | | |
PEO [Member] | Bradley L. Campbell [Member] | Year Over Year Change in Fair Value at Covered Fiscal Year End of Awards Granted in Any Prior Fiscal Year Outstanding and Unvested at the Covered Fiscal Year End [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 188,427 | | |
PEO [Member] | Bradley L. Campbell [Member] | Vesting Date Fair Value of Awards Granted and Vested During the Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 0 | | |
PEO [Member] | Bradley L. Campbell [Member] | Change Vesting Date From the End of the Prior Fiscal Year in Fair Value of Awards Granted in Any Prior Fiscal Year for Which Vesting Conditions Satisfied During the Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 167,091 | | |
PEO [Member] | Bradley L. Campbell [Member] | Fair Value at End of Prior Fiscal Year of Awards Granted in Any Prior Fiscal Year that Failed to Meet the Applicable Vesting Conditions During the Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | (691,730) | | |
Non-PEO NEO [Member] | Aggregate Value for Stock Awards and Option Awards included in SCT Total for Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | (2,540,515) | (2,536,712) | (2,444,876) |
Non-PEO NEO [Member] | Fair Value at Year End of Awards Granted During Covered Fiscal Year Outstanding and Unvested at the Covered Fiscal Year End [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 2,670,154 | 1,127,092 | 5,365,039 |
Non-PEO NEO [Member] | Year Over Year Change in Fair Value at Covered Fiscal Year End of Awards Granted in Any Prior Fiscal Year Outstanding and Unvested at the Covered Fiscal Year End [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 107,386 | (3,516,814) | 2,592,973 |
Non-PEO NEO [Member] | Vesting Date Fair Value of Awards Granted and Vested During the Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 0 | 0 | 12,278 |
Non-PEO NEO [Member] | Change Vesting Date From the End of the Prior Fiscal Year in Fair Value of Awards Granted in Any Prior Fiscal Year for Which Vesting Conditions Satisfied During the Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | 86,488 | (1,712,039) | 502,296 |
Non-PEO NEO [Member] | Fair Value at End of Prior Fiscal Year of Awards Granted in Any Prior Fiscal Year that Failed to Meet the Applicable Vesting Conditions During the Covered Fiscal Year [Member] | | | | | |
Pay vs Performance Disclosure [Table] | | | | | |
Adjustment to Compensation Amount | | | $ (385,391) | $ (350,407) | $ (262,789) |