| Document and Entity Information | Jul. 20, 2023 |
| Cover [Abstract] | |
| Amendment Flag | true |
| Entity Central Index Key | 0001200375 |
| Document Type | 8-K/A |
| Document Period End Date | Jul. 20, 2023 |
| Entity Registrant Name | Codexis, Inc. |
| Entity Incorporation State Country Code | DE |
| Entity File Number | 001-34705 |
| Entity Tax Identification Number | 71-0872999 |
| Entity Address, Address Line One | 200 Penobscot Drive |
| Entity Address, City or Town | Redwood City |
| Entity Address, State or Province | CA |
| Entity Address, Postal Zip Code | 94063 |
| City Area Code | (650) |
| Local Phone Number | 421-8100 |
| Written Communications | false |
| Soliciting Material | false |
| Pre Commencement Tender Offer | false |
| Pre Commencement Issuer Tender Offer | false |
| Security 12b Title | Common Stock, par value $0.0001 per share |
| Trading Symbol | CDXS |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | false |
| Amendment Description | This Current Report on Form 8-K/A (this “Current Report”) amends the Current Report on Form 8-K filed by Codexis, Inc. (the “Company”) with the Securities and Exchange Commission (the “SEC”) on July 20, 2023 (the “Original Report”) and is being filed in order to update the Company’s disclosure under Item 2.05 and Item 2.06 of the Original Report. The Original Report otherwise remains unchanged. |
