Bio-Rad Laboratories (BIO) S-3ASR Automatic shelf registration

Exhibit 12.1

Statement of Computation of Ratios ($000)	Bio-Rad Laboratories, Inc.
	For the Nine Months Ended September 30,		Year Ended December 31,
	2010		2009			2008			2007		2006		2005
Earnings
Add:
Income before income taxes	$	163,082	$	185,832		$	142,843		$	120,843	$	142,027	$	93,371
Fixed charges		53,528		61,367			47,001			43,432		41,800		41,765
Amortization of capitalized interest		239		202			37			34		34		30
Subtract:
Capitalized interest		—		(524	)		(1,032	)		—		—		(313	)
Total Earnings	$	216,849	$	246,877		$	188,849		$	164,309	$	183,861	$	134,853
Fixed Charges
Add:
Interest expensed		43,169		47,024			32,113			31,606		32,022		32,643
Capitalized interest		—		524			1,032			—		—		313
Amortized premiums, discounts and capitalized expenses related to indebtedness		1,468		1,600			1,063			1,014		974		978
Estimated interest within rental expense		8,891		12,219			12,793			10,812		8,804		7,831
Total Fixed Charges	$	53,528	$	61,367		$	47,001		$	43,432	$	41,800	$	41,765
Ratio of Earnings to Fixed Charges		4.1		4.0			4.0			3.8		4.4		3.2