The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
ABEONA THERAPEUTICS INC | *W EXP 12/24/201 | 00289Y115 | 4,285 | 1,259,636 | SH | SOLE | 1,259,636 | 0 | 0 | ||
ABEONA THERAPEUTICS INC | COM | 00289Y107 | 2,706 | 422,873 | SH | SOLE | 422,873 | 0 | 0 | ||
ACASTI PHARMA INC | COM | 00430K402 | 247 | 186,559 | SH | SOLE | 186,559 | 0 | 0 | ||
ACCELERON PHARMA INC | COM | 00434H108 | 21,615 | 711,259 | SH | SOLE | 711,259 | 0 | 0 | ||
ACELRX PHARMACEUTICALS INC | COM | 00444T100 | 8,022 | 3,731,342 | SH | SOLE | 3,731,342 | 0 | 0 | ||
ACHAOGEN INC | COM | 004449104 | 599 | 27,551 | SH | SOLE | 27,551 | 0 | 0 | ||
ACORDA THERAPEUTICS INC | COM | 00484M106 | 626 | 31,786 | SH | SOLE | 31,786 | 0 | 0 | ||
ADAMIS PHARMACEUTICALS CORP | COM NEW | 00547W208 | 2,080 | 400,000 | SH | SOLE | 400,000 | 0 | 0 | ||
ADMA BIOLOGICS INC | COM | 000899104 | 2,769 | 721,102 | SH | SOLE | 721,102 | 0 | 0 | ||
AFFIMED N V | COM | N01045108 | 1,369 | 668,214 | SH | SOLE | 668,214 | 0 | 0 | ||
AKEBIA THERAPEUTICS INC | COM | 00972D105 | 15,808 | 1,100,000 | SH | SOLE | 1,100,000 | 0 | 0 | ||
ALBIREO PHARMA INC | COM | 01345P106 | 17,407 | 845,000 | SH | SOLE | 845,000 | 0 | 0 | ||
ALDEYRA THERAPEUTICS INC | COM | 01438T106 | 13,417 | 2,885,458 | SH | SOLE | 2,885,458 | 0 | 0 | ||
ALLIQUA BIOMEDICAL INC | COM NEW | 019621200 | 1,566 | 4,233,951 | SH | SOLE | 4,233,951 | 0 | 0 | ||
ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 146,181 | 1,832,761 | SH | SOLE | 1,832,761 | 0 | 0 | ||
AMICUS THERAPEUTICS INC | COM | 03152W109 | 174,178 | 17,296,672 | SH | SOLE | 17,296,672 | 0 | 0 | ||
ANAPTYSBIO INC | COM | 032724106 | 22,788 | 952,269 | SH | SOLE | 952,269 | 0 | 0 | ||
ANI PHARMACEUTICALS INC | NOTE 3.000%12/0 | 00182CAA1 | 7,908 | 7,500,000 | PRN | SOLE | 7,500,000 | 0 | 0 | ||
ANI PHARMACEUTICALS INC | COM | 00182C103 | 5,869 | 125,399 | SH | SOLE | 125,399 | 0 | 0 | ||
ANTARES PHARMA INC | COM | 036642106 | 13,741 | 4,267,253 | SH | SOLE | 4,267,253 | 0 | 0 | ||
ARDELYX INC | COM | 039697107 | 9,233 | 1,810,581 | SH | SOLE | 1,810,581 | 0 | 0 | ||
ARGENX SE | SPONSORED ADR | 04016X101 | 9,544 | 450,000 | SH | SOLE | 450,000 | 0 | 0 | ||
ARNO THERAPEUTICS INC | COM | 042564203 | 208 | 4,177,577 | SH | SOLE | 4,177,577 | 0 | 0 | ||
ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 | 1,372 | 847,458 | SH | SOLE | 847,458 | 0 | 0 | ||
ASSEMBLY BIOSCIENCES INC | COM | 045396108 | 9,124 | 441,833 | SH | SOLE | 441,833 | 0 | 0 | ||
AUDENTES THERAPEUTICS INC | COM | 05070R104 | 13,534 | 707,500 | SH | SOLE | 707,500 | 0 | 0 | ||
AVADEL PHARMACEUTICALS PLC | SPONSORED ADR | 05337M104 | 15,763 | 1,429,114 | SH | SOLE | 1,429,114 | 0 | 0 | ||
AVEO PHARMACEUTICALS INC | COM | 053588109 | 13,343 | 6,010,660 | SH | SOLE | 6,010,660 | 0 | 0 | ||
AVEXIS INC | COM | 05366U100 | 22,280 | 271,181 | SH | SOLE | 271,181 | 0 | 0 | ||
AXOVANT SCIENCES LTD | COM | G0750W104 | 6,957 | 300,000 | SH | Call | SOLE | 0 | 0 | 0 | |
AXOVANT SCIENCES LTD | COM | G0750W104 | 13,281 | 572,700 | SH | SOLE | 572,700 | 0 | 0 | ||
AZURRX BIOPHARMA INC | COM | 05502L105 | 916 | 227,272 | SH | SOLE | 227,272 | 0 | 0 | ||
BIOHAVEN PHARMACTL HLDG CO L | COM | G11196105 | 3,000 | 120,000 | SH | SOLE | 120,000 | 0 | 0 | ||
BLUEBIRD BIO INC | COM | 09609G100 | 2,101 | 20,000 | SH | SOLE | 20,000 | 0 | 0 | ||
BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 22,530 | 444,661 | SH | SOLE | 444,661 | 0 | 0 | ||
BRAINSTORM CELL THERAPEUTICS | COM NEW | 10501E201 | 1,660 | 400,000 | SH | SOLE | 400,000 | 0 | 0 | ||
CAPITAL SR LIVING CORP | COM | 140475104 | 8,064 | 530,173 | SH | SOLE | 530,173 | 0 | 0 | ||
CARA THERAPEUTICS INC | COM | 140755109 | 1,539 | 100,000 | SH | Call | SOLE | 0 | 0 | 0 | |
CENTENE CORP DEL | COM | 15135B101 | 617 | 7,726 | SH | SOLE | 7,726 | 0 | 0 | ||
CHAMPIONS ONCOLOGY INC | COM NEW | 15870P307 | 943 | 366,973 | SH | SOLE | 366,973 | 0 | 0 | ||
CIDARA THERAPEUTICS INC | COM | 171757107 | 465 | 62,110 | SH | SOLE | 62,110 | 0 | 0 | ||
CLEARSIDE BIOMEDICAL INC | COM | 185063104 | 5,649 | 620,181 | SH | SOLE | 620,181 | 0 | 0 | ||
CORBUS PHARMACEUTICALS HLDGS | COM | 21833P103 | 7,764 | 1,232,500 | SH | SOLE | 1,232,500 | 0 | 0 | ||
CORIUM INTL INC | COM | 21887L107 | 43,620 | 5,847,133 | SH | SOLE | 5,847,133 | 0 | 0 | ||
CURIS INC | COM | 231269101 | 1,798 | 951,201 | SH | SOLE | 951,201 | 0 | 0 | ||
CUTERA INC | COM | 232109108 | 310 | 11,981 | SH | SOLE | 11,981 | 0 | 0 | ||
CYTOMX THERAPEUTICS INC | COM | 23284F105 | 21,550 | 1,390,381 | SH | SOLE | 1,390,381 | 0 | 0 | ||
DBV TECHNOLOGIES S A | SPONSORED ADR | 23306J101 | 21,131 | 591,765 | SH | SOLE | 591,765 | 0 | 0 | ||
DIPLOMAT PHARMACY INC | COM | 25456K101 | 454 | 30,658 | SH | SOLE | 30,658 | 0 | 0 | ||
DOVA PHARMACEUTICALS INC | COM | 25985T102 | 38,037 | 1,706,499 | SH | SOLE | 1,706,499 | 0 | 0 | ||
EAGLE PHARMACEUTICALS INC | COM | 269796108 | 7,889 | 100,000 | SH | SOLE | 100,000 | 0 | 0 | ||
EDWARDS LIFESCIENCES CORP | COM | 28176E108 | 719 | 6,088 | SH | SOLE | 6,088 | 0 | 0 | ||
EIGER BIOPHARMACEUTICALS INC | COM | 28249U105 | 1,245 | 157,679 | SH | SOLE | 157,679 | 0 | 0 | ||
EVOLENT HEALTH INC | CL A | 30050B101 | 27,234 | 1,074,327 | SH | SOLE | 1,074,327 | 0 | 0 | ||
EXACT SCIENCES CORP | COM | 30063P105 | 3,537 | 100,000 | SH | SOLE | 100,000 | 0 | 0 | ||
EXELIXIS SHARES | COM | 30161Q104 | 1,142 | 46,361 | SH | SOLE | 46,361 | 0 | 0 | ||
FERRARI N V | COM | N3167Y103 | 533 | 6,200 | SH | SOLE | 6,200 | 0 | 0 | ||
FIAT CHRYSLER AUTOMOBILES N | SHS | N31738102 | 659 | 62,000 | SH | SOLE | 62,000 | 0 | 0 | ||
FOAMIX PHARMACEUTICALS LTD | SHS | M46135105 | 5,184 | 1,117,324 | SH | SOLE | 1,117,324 | 0 | 0 | ||
FORWARD PHARMA A/S | SPONSORED ADR | 34986J105 | 3,959 | 194,718 | SH | SOLE | 194,718 | 0 | 0 | ||
GALAPAGOS NV | SPON ADR | 36315X101 | 17,325 | 226,405 | SH | SOLE | 226,405 | 0 | 0 | ||
GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 107,592 | 3,933,927 | SH | SOLE | 3,933,927 | 0 | 0 | ||
HESKA CORP | COM RESTRC NEW | 42805E306 | 745 | 7,300 | SH | SOLE | 7,300 | 0 | 0 | ||
HISTOGENICS CORP | COM | 43358V109 | 3,182 | 1,777,777 | SH | SOLE | 1,777,777 | 0 | 0 | ||
HILL ROM HLDGS INC | COM | 431475102 | 631 | 7,930 | SH | SOLE | 7,930 | 0 | 0 | ||
HUMANA INC | COM | 444859102 | 18,791 | 78,093 | SH | SOLE | 78,093 | 0 | 0 | ||
ICON PLC | SHS | G4705A100 | 507 | 5,187 | SH | SOLE | 5,187 | 0 | 0 | ||
INC RESH HLDGS INC | CL A | 45329R109 | 499 | 8,532 | SH | SOLE | 8,532 | 0 | 0 | ||
INCYTE CORP | COM | 45337C102 | 707 | 5,619 | SH | SOLE | 5,619 | 0 | 0 | ||
INTUITIVE SURGICAL INC | COM NEW | 46120E602 | 19,357 | 20,695 | SH | SOLE | 20,695 | 0 | 0 | ||
INVITAE CORP | COM | 46185L103 | 6,209 | 649,500 | SH | SOLE | 649,500 | 0 | 0 | ||
IOVANCE BIOTHERAPEUTICS INC | COM | 462260100 | 32,068 | 4,363,114 | SH | SOLE | 4,363,114 | 0 | 0 | ||
IRHYTHM TECHNOLOGIES INC | COM | 450056106 | 12,019 | 282,857 | SH | SOLE | 282,857 | 0 | 0 | ||
JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 | 13,306 | 85,572 | SH | SOLE | 85,572 | 0 | 0 | ||
KADMON HLDGS INC | COM | 48283N106 | 20,172 | 5,185,847 | SH | SOLE | 5,185,847 | 0 | 0 | ||
LA JOLLA PHARMACEUTICAL CO | COM PAR $.0001 2 | 503459604 | 64,214 | 2,157,011 | SH | SOLE | 2,157,011 | 0 | 0 | ||
LANTHEUS HLDGS INC | COM | 516544103 | 949 | 53,763 | SH | SOLE | 53,763 | 0 | 0 | ||
LHC GROUP INC | COM | 50187A107 | 728 | 10,730 | SH | SOLE | 10,730 | 0 | 0 | ||
MGC DIAGNOSTICS CORP | COM | 552768103 | 2,140 | 252,327 | SH | SOLE | 252,327 | 0 | 0 | ||
MOLINA HEALTHCARE INC | COM | 60855R100 | 563 | 8,140 | SH | SOLE | 8,140 | 0 | 0 | ||
MYOKARDIA INC | COM | 62857M105 | 14,492 | 553,154 | SH | SOLE | 553,154 | 0 | 0 | ||
NEPTUNE TECHNOLOGIES BIORESO | COM | 64077P108 | 3,801 | 6,519,634 | SH | SOLE | 6,519,634 | 0 | 0 | ||
NEUROCRINE BIOSCIENCES INC | COM | 64125C109 | 164,569 | 3,577,589 | SH | SOLE | 3,577,589 | 0 | 0 | ||
NXSTAGE MEDICAL INC | COM | 67072V103 | 38,997 | 1,555,523 | SH | SOLE | 1,555,523 | 0 | 0 | ||
OCERA THERAPEUTICS INC | COM | 67552A108 | 2,365 | 2,038,880 | SH | SOLE | 2,038,880 | 0 | 0 | ||
ONCOBIOLOGICS INC | W EXP 02/18/201 | 68235M113 | 80 | 462,500 | SH | SOLE | 462,500 | 0 | 0 | ||
ONCOBIOLOGICS INC | *W EXP 05/18/201 | 68235M121 | 42 | 462,500 | SH | SOLE | 462,500 | 0 | 0 | ||
ONCOBIOLOGICS INC | COM | 68235M105 | 837 | 837,886 | SH | SOLE | 837,886 | 0 | 0 | ||
ORASURE TECHNOLOGIES INC | COM | 68554V108 | 945 | 54,729 | SH | SOLE | 54,729 | 0 | 0 | ||
OXFORD IMMUNOTEC GLOBAL PLC | ORD SHS | G6855A103 | 741 | 44,106 | SH | SOLE | 44,106 | 0 | 0 | ||
PEREGRINE PHARMACEUTICALS IN | COM NEW | 713661304 | 15 | 24,332 | SH | SOLE | 24,332 | 0 | 0 | ||
PERNIX THERAPEUTICS HLDGS IN | DBCV 4.250% 4/0 | 71426VAK4 | 282 | 1,000,000 | PRN | SOLE | 1,000,000 | 0 | 0 | ||
PFENEX INC | COM | 717071104 | 3,392 | 845,973 | SH | SOLE | 845,973 | 0 | 0 | ||
PORTOLA PHARMACEUTICALS INC | COM | 737010108 | 442 | 7,870 | SH | SOLE | 7,870 | 0 | 0 | ||
PROTEON THERAPEUTICS INC | COM | 74371L109 | 518 | 334,116 | SH | SOLE | 334,116 | 0 | 0 | ||
PSIVIDA CORP | COM | 74440J101 | 1,966 | 1,149,556 | SH | SOLE | 1,149,556 | 0 | 0 | ||
PUMA BIOTECHNOLOGY INC | COM | 74587V107 | 64,092 | 733,320 | SH | SOLE | 733,320 | 0 | 0 | ||
QUOTIENT LTD | SHS | G73268107 | 26,010 | 3,714,486 | SH | SOLE | 3,714,486 | 0 | 0 | ||
RADIUS HEALTH INC | COM NEW | 750469207 | 9,046 | 200,000 | SH | Put | SOLE | 200,000 | 0 | 0 | |
RADIUS HEALTH INC | COM NEW | 750469207 | 29,212 | 645,873 | SH | SOLE | 645,873 | 0 | 0 | ||
REGENXBIO INC | COM | 75901B107 | 27,080 | 1,371,186 | SH | SOLE | 1,371,186 | 0 | 0 | ||
RETROPHIN INC | COM | 761299106 | 51,816 | 2,672,309 | SH | SOLE | 2,672,309 | 0 | 0 | ||
SAGE THERAPEUTICS INC | COM | 78667J108 | 21,901 | 275,000 | SH | Call | SOLE | 0 | 0 | 0 | |
SAREPTA THERAPEUTICS | COM | 803607100 | 36,743 | 1,089,961 | SH | SOLE | 1,089,961 | 0 | 0 | ||
SELECTA BIOSCIENCES INC | COM | 816212104 | 15,834 | 797,325 | SH | SOLE | 797,325 | 0 | 0 | ||
SIERRA ONCOLOGY INC | COM | 82640U107 | 4,277 | 3,655,186 | SH | SOLE | 3,655,186 | 0 | 0 | ||
TESARO INC | COM | 881569107 | 50,287 | 359,551 | SH | SOLE | 359,551 | 0 | 0 | ||
ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 | 6,211 | 100,000 | SH | Call | SOLE | 0 | 0 | 0 | |
UNIQURE NV | SHS | N90064101 | 6,748 | 1,090,119 | SH | SOLE | 1,090,119 | 0 | 0 | ||
UNITEDHEALTH GROUP INC | COM | 91324P102 | 5,281 | 28,480 | SH | SOLE | 28,480 | 0 | 0 | ||
UROGEN PHARMA LTD | COM | M96088105 | 4,858 | 269,014 | SH | SOLE | 269,014 | 0 | 0 | ||
VANDA PHARMACEUTICALS INC | COM | 921659108 | 591 | 36,232 | SH | SOLE | 36,232 | 0 | 0 | ||
VBI VACCINES IN | COM NEW | 91822J103 | 28,561 | 6,565,843 | SH | SOLE | 6,565,843 | 0 | 0 | ||
VERONA PHARMA PLC | SPONSORED ADS | 925050106 | 2,331 | 200,000 | SH | SOLE | 200,000 | 0 | 0 | ||
VERSARTIS INC | COM | 92529L102 | 76,907 | 4,407,317 | SH | SOLE | 4,407,317 | 0 | 0 | ||
VERTEX PHARMACEUTICALS INC | COM | 92532F100 | 35,742 | 277,352 | SH | SOLE | 277,352 | 0 | 0 | ||
VIVEVE MED INC | COM NEW | 92852W204 | 6,394 | 890,468 | SH | SOLE | 890,468 | 0 | 0 | ||
VOYAGER THERAPEUTICS INC | COM | 92915B106 | 310 | 34,604 | SH | SOLE | 34,604 | 0 | 0 | ||
WAVE LIFE SCIENCES LTD | SHS | Y95308105 | 12,328 | 662,798 | SH | SOLE | 662,798 | 0 | 0 | ||
WELLCARE HEALTH PLANS INC | COM | 94946T106 | 908 | 5,056 | SH | SOLE | 5,056 | 0 | 0 | ||
XENCOR INC | COM | 98401F105 | 27,297 | 1,293,095 | SH | SOLE | 1,293,095 | 0 | 0 | ||
XENON PHARMACEUTICALS INC | COM | 98420N105 | 2,280 | 723,853 | SH | SOLE | 723,853 | 0 | 0 | ||
ZOGENIX INC | COM NEW | 98978L204 | 50,000 | 3,448,302 | SH | SOLE | 3,448,302 | 0 | 0 | ||
ZOSANO PHARMA CORP | COM | 98979H103 | 705 | 500,000 | SH | SOLE | 500,000 | 0 | 0 | ||
ZYMEWORKS INC | COM | 98985W102 | 6,101 | 730,768 | SH | SOLE | 730,768 | 0 | 0 | ||
ZYNERBA PHARMACEUTICALS INC | COM | 98986X109 | 10,164 | 100,000 | SH | Put | SOLE | 100,000 | 0 | 0 |