The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
ABBOTT LABORATORIES | COM | 002824100 | 1,921 | 50,000 | SH | SOLE | 0 | 0 | 0 | ||
ABEONA THERAPEUTICS | COM | 00289Y107 | 4,085 | 842,173 | SH | SOLE | 0 | 0 | 0 | ||
ABEONA THERAPEUTICS CW-19 | WARRANTS | 00289y115 | 3,778 | 1,259,636 | SH | SOLE | 0 | 0 | 0 | ||
ABIOMED | COM | 003654100 | 12 | 109 | SH | SOLE | 0 | 0 | 0 | ||
ACORDA THERAPEUTICS | COM | 00484M106 | 13,536 | 720,000 | SH | SOLE | 0 | 0 | 0 | ||
ACADIA PHARMACEUTICALS INC CALL 40 01/20/2017 | COM | 004225108 | 0 | 5,200 | SH | Call | SOLE | 0 | 0 | 0 | |
ACADIA PHARMACEUTICALS INC CALL 40 01/20/2017 | COM | 004225108 | 7 | 94,800 | SH | Call | SOLE | 0 | 0 | 0 | |
ACASTI PHARMA CLASS A | COM | 00430K402 | 233 | 186,559 | SH | SOLE | 0 | 0 | 0 | ||
ACCELERON PHARMA | COM | 00434H108 | 15,822 | 619,987 | SH | SOLE | 0 | 0 | 0 | ||
ACCRETIVE HEALTH | COM | 00438V103 | 709 | 315,000 | SH | SOLE | 0 | 0 | 0 | ||
ACELRX PHARMACEUTICALS | COM | 00444T100 | 14,063 | 5,408,728 | SH | SOLE | 0 | 0 | 0 | ||
ACLARIS THERAPEUTICS | COM | 00461U105 | 34,219 | 1,260,847 | SH | SOLE | 0 | 0 | 0 | ||
ADMA BIOLOGICS | COM | 000899104 | 3,692 | 721,102 | SH | SOLE | 0 | 0 | 0 | ||
AEGLEA BIOTHERAPEUTICS | COM | 00773J103 | 451 | 103,585 | SH | SOLE | 0 | 0 | 0 | ||
AERIE PHARMACEUTICALS | COM | 00771V108 | 1,893 | 50,000 | SH | SOLE | 0 | 0 | 0 | ||
AEVI GENOMIC MEDICINE WARRANT | WARRANTS | 58436Q120 | 106 | 150,000 | SH | SOLE | 0 | 0 | 0 | ||
AEVI GENOMIC MEDICINE | COM | 00835P105 | 1,520 | 293,460 | SH | SOLE | 0 | 0 | 0 | ||
AFFIMED | COM | N01045108 | 1,322 | 734,301 | SH | SOLE | 0 | 0 | 0 | ||
AGENUS | COM | 00847G705 | 297 | 72,187 | SH | SOLE | 0 | 0 | 0 | ||
AGILE THERAPEUTICS | COM | 00847L100 | 3,770 | 661,446 | SH | SOLE | 0 | 0 | 0 | ||
AKEBIA THERAPEUTICS | COM | 00972D105 | 5,593 | 537,256 | SH | SOLE | 0 | 0 | 0 | ||
ALDER BIOPHARMACEUTICALS | COM | 014339105 | 7,991 | 384,169 | SH | SOLE | 0 | 0 | 0 | ||
ALDEYRA THERAPEUTICS | COM | 01438T106 | 10,381 | 1,940,458 | SH | SOLE | 0 | 0 | 0 | ||
ALLIQUA BIOMEDICAL | COM | 019621200 | 1,133 | 1,921,951 | SH | SOLE | 0 | 0 | 0 | ||
ALLON THERAPEUTICS | COM | 019774108 | 0 | 751,124 | SH | SOLE | 0 | 0 | 0 | ||
ALNYLAM PHARMACEUTICALS | COM | 02043Q107 | 4,436 | 118,475 | SH | SOLE | 0 | 0 | 0 | ||
AMAG PHARMACEUTICALS | COM | 00163U106 | 679 | 19,524 | SH | SOLE | 0 | 0 | 0 | ||
AMICUS THERAPEUTICS | COM | 03152W109 | 85,964 | 17,296,672 | SH | SOLE | 0 | 0 | 0 | ||
AMN HEALTHCARE | COM | 001744101 | 484 | 12,585 | SH | SOLE | 0 | 0 | 0 | ||
ANI PHARMACEUTICALS | COM | 00182C103 | 16,192 | 267,100 | SH | SOLE | 0 | 0 | 0 | ||
ANI PHARMACEUTICALS INC 01DEC19 3.0PCT | NOTE | 00182CAA1 | 8,700 | 7,500,000 | PRN | SOLE | 0 | 0 | 0 | ||
ANTARES PHARMA | COM | 036642106 | 6,797 | 2,917,253 | SH | SOLE | 0 | 0 | 0 | ||
APPLIED GENETIC TECHNOLOGIES | COM | 03820J100 | 470 | 50,251 | SH | SOLE | 0 | 0 | 0 | ||
APTEVO THERAPEUTICS | COM | 03835L108 | 2,411 | 988,133 | SH | SOLE | 0 | 0 | 0 | ||
ARDELYX | COM | 039697107 | 26,073 | 1,836,196 | SH | SOLE | 0 | 0 | 0 | ||
ARIAD PHARMACEUTICALS | COM | 04033A100 | 19 | 1,551 | SH | SOLE | 0 | 0 | 0 | ||
ARNO THERAPEUTICS INC | COM | 042564203 | 781 | 4,177,577 | SH | SOLE | 0 | 0 | 0 | ||
ARROWHEAD Pharmaceuticals | com | 04280a100 | 1,313 | 847,458 | SH | SOLE | 0 | 0 | 0 | ||
ASSEMBLY BIOSCIENCES | COM | 045396108 | 8,679 | 714,354 | SH | SOLE | 0 | 0 | 0 | ||
ATRICURE | COM | 04963C209 | 1,847 | 94,400 | SH | SOLE | 0 | 0 | 0 | ||
AUDENTES THERAPEUTICS | COM | 05070R104 | 137 | 7,500 | SH | SOLE | 0 | 0 | 0 | ||
AVADEL PHARMACEUTICALS | COM | 05337M104 | 14,424 | 1,388,240 | SH | SOLE | 0 | 0 | 0 | ||
AVEO PHARMACEUTICALS | COM | 053588109 | 1,678 | 3,108,808 | SH | SOLE | 0 | 0 | 0 | ||
AVEXIS | COM | 05366U100 | 22,602 | 473,531 | SH | SOLE | 0 | 0 | 0 | ||
AVINGER | COM | 053734109 | 4 | 1,062 | SH | SOLE | 0 | 0 | 0 | ||
AZURRX BIOPHARMA | COM | 05502L105 | 1,077 | 227,272 | SH | SOLE | 0 | 0 | 0 | ||
BARCLAYS BANK IPATH SandP 500 VIX SHORT TERM FUTURES ETN EXP | COM | 06740Q252 | 1,046 | 41,000 | SH | SOLE | 0 | 0 | 0 | ||
BIO RAD LABORATORIES CLASS A | COM | 090572207 | 4,451 | 24,416 | SH | SOLE | 0 | 0 | 0 | ||
BIOCRYST PHARMACEUTICALS | COM | 09058V103 | 8,420 | 1,330,240 | SH | SOLE | 0 | 0 | 0 | ||
BIOGEN INC | COM | 09062X103 | 545 | 1,922 | SH | SOLE | 0 | 0 | 0 | ||
BIOMARIN PHARMACEUTICAL | COM | 09061G101 | 21 | 250 | SH | SOLE | 0 | 0 | 0 | ||
BLUEPRINT MEDICINES | COM | 09627Y109 | 7,680 | 273,820 | SH | SOLE | 0 | 0 | 0 | ||
BOSTON SCIENTIFIC | COM | 101137107 | 0 | 3 | SH | SOLE | 0 | 0 | 0 | ||
BRAINSTORM CELL THERAPEUTICS | COM | 10501E201 | 1,016 | 400,000 | SH | SOLE | 0 | 0 | 0 | ||
BRUKER | COM | 116794108 | 0 | 3 | SH | SOLE | 0 | 0 | 0 | ||
CAPITAL SENIOR LIVING | COM | 140475104 | 5,222 | 320,173 | SH | SOLE | 0 | 0 | 0 | ||
CAPRICOR THERAPEUTICS | COM | 14070B101 | 11 | 4,000 | SH | SOLE | 0 | 0 | 0 | ||
CASCADIAN THERAPEUTICS | COM | 14740B606 | 2,355 | 546,498 | SH | SOLE | 0 | 0 | 0 | ||
CATALENT | COM | 148806102 | 0 | 3 | SH | SOLE | 0 | 0 | 0 | ||
CELGENE | COM | 151020104 | 3,010 | 26,000 | SH | SOLE | 0 | 0 | 0 | ||
CEMPRA | COM | 15130J109 | 62 | 22,321 | SH | SOLE | 0 | 0 | 0 | ||
CHAMPIONS ONCOLOGY | COM | 15870P307 | 942 | 372,597 | SH | SOLE | 0 | 0 | 0 | ||
CHINA BIOLOGIC PRODUCTS | COM | 16938C106 | 25 | 236 | SH | SOLE | 0 | 0 | 0 | ||
CIDARA THERAPEUTICS | COM | 171757107 | 8,043 | 773,369 | SH | SOLE | 0 | 0 | 0 | ||
CLEARSIDE BIOMEDICAL | COM | 185063104 | 6,365 | 712,062 | SH | SOLE | 0 | 0 | 0 | ||
CLOVIS ONCOLOGY | COM | 189464100 | 7,452 | 167,754 | SH | SOLE | 0 | 0 | 0 | ||
COLLEGIUM PHARMACEUTICAL | COM | 19459J104 | 3,063 | 196,728 | SH | SOLE | 0 | 0 | 0 | ||
COLUCID PHARMACEUTICALS | COM | 19716T101 | 23,346 | 641,364 | SH | SOLE | 0 | 0 | 0 | ||
CORBUS PHARMACEUTICALS HOLDINGS INC CALL 15 01/20/2017 | COM | 21833P103 | 0 | 1,600 | SH | Call | SOLE | 0 | 0 | 0 | |
CORBUS PHARMACEUTICALS HOLDINGS INC | COM | 21833P103 | 10,562 | 1,250,000 | SH | SOLE | 0 | 0 | 0 | ||
CROSS COUNTRY HEALTHCARE | COM | 227483104 | 544 | 34,819 | SH | SOLE | 0 | 0 | 0 | ||
CRYOLIFE | COM | 228903100 | 2 | 123 | SH | SOLE | 0 | 0 | 0 | ||
CYNOSURE CLASS A | COM | 232577205 | 82 | 1,800 | SH | SOLE | 0 | 0 | 0 | ||
CYTOMX THERAPEUTICS | COM | 23284F105 | 10,152 | 923,763 | SH | SOLE | 0 | 0 | 0 | ||
DANAHER | COM | 235851102 | 0 | 3 | SH | SOLE | 0 | 0 | 0 | ||
DAVITA | COM | 23918K108 | 0 | 3 | SH | SOLE | 0 | 0 | 0 | ||
DBV TECHNOLOGIES ADR REPRESENTING 0.5 | COM | 23306J101 | 21,452 | 610,643 | SH | SOLE | 0 | 0 | 0 | ||
DERMIRA | COM | 24983L104 | 9,875 | 325,583 | SH | SOLE | 0 | 0 | 0 | ||
DYNAVAX TECHNOLOGIES CALL 4 01/2017 | COM | 268158201 | 5 | 15,600 | SH | Call | SOLE | 0 | 0 | 0 | |
EAGLE PHARMACEUTICALS | COM | 269796108 | 39,527 | 498,198 | SH | SOLE | 0 | 0 | 0 | ||
EIGER BIOPHARMACEUTICALS | COM | 28249U105 | 1,836 | 157,679 | SH | SOLE | 0 | 0 | 0 | ||
ELI LILLY & CO CALL 90 01/20/2017 | COM | 532457108 | 3 | 100,000 | SH | Call | SOLE | 0 | 0 | 0 | |
ENDO INTERNATIONAL | COM | G30401106 | 213 | 12,920 | SH | SOLE | 0 | 0 | 0 | ||
ENZO BIOCHEM | COM | 294100102 | 582 | 83,893 | SH | SOLE | 0 | 0 | 0 | ||
EVOLENT HEALTH CLASS A | COM | 30050B101 | 4,555 | 307,800 | SH | SOLE | 0 | 0 | 0 | ||
EXACT SCIENCES CORP PUT 17 01/20/2017 | COM | 30063P105 | 670 | 200,000 | SH | Put | SOLE | 0 | 0 | 0 | |
EXELIXIS | COM | 30161Q104 | 691 | 46,361 | SH | SOLE | 0 | 0 | 0 | ||
EXPRESS SCRIPTS HOLDING | COM | 30219G108 | 457 | 6,639 | SH | SOLE | 0 | 0 | 0 | ||
FERRARI | COM | N3167Y103 | 360 | 6,200 | SH | SOLE | 0 | 0 | 0 | ||
FIAT CHRYSLER AUTOMOBILES | COM | N31738102 | 565 | 62,000 | SH | SOLE | 0 | 0 | 0 | ||
FIVE PRIME THERAPEUTICS | COM | 33830X104 | 8,181 | 163,255 | SH | SOLE | 0 | 0 | 0 | ||
FIVE STAR QUALITY CARE | COM | 33832D106 | 183 | 67,797 | SH | SOLE | 0 | 0 | 0 | ||
FLEX PHARMA | COM | 33938A105 | 1 | 237 | SH | SOLE | 0 | 0 | 0 | ||
FOAMIX PHARMACEUTICALS | COM | M46135105 | 14,685 | 1,322,994 | SH | SOLE | 0 | 0 | 0 | ||
FORWARD PHARMA ADR REPRESENTING 1 | COM | 34986J105 | 5,918 | 394,241 | SH | SOLE | 0 | 0 | 0 | ||
GALAPAGOS ADR REPRESENTING | COM | 36315X101 | 20,631 | 304,531 | SH | SOLE | 0 | 0 | 0 | ||
GENVEC | COM | 37246C406 | 180 | 56,131 | SH | SOLE | 0 | 0 | 0 | ||
GLAUKOS | COM | 377322102 | 10 | 300 | SH | SOLE | 0 | 0 | 0 | ||
GLOBAL BLOOD THERAPEUTICS | COM | 37890U108 | 45,213 | 3,128,978 | SH | SOLE | 0 | 0 | 0 | ||
HILL ROM HOLDINGS | COM | 431475102 | 445 | 7,930 | SH | SOLE | 0 | 0 | 0 | ||
HISTOGENCIS CORP | COM | 43358V109 | 2,968 | 1,777,777 | SH | SOLE | 0 | 0 | 0 | ||
HUMANA | COM | 444859102 | 454 | 2,227 | SH | SOLE | 0 | 0 | 0 | ||
HUMANA INC CALL 210 04/21/2017 | COM | 444859102 | 528 | 40,000 | SH | Call | SOLE | 0 | 0 | 0 | |
ICON | COM | G4705A100 | 517 | 6,873 | SH | SOLE | 0 | 0 | 0 | ||
IGNYTA | COM | 451731103 | 35 | 6,584 | SH | SOLE | 0 | 0 | 0 | ||
IMMUNE DESIGN | COM | 45252L103 | 428 | 77,725 | SH | SOLE | 0 | 0 | 0 | ||
IMPAX LABORATORIES | COM | 45256B101 | 0 | 1 | SH | SOLE | 0 | 0 | 0 | ||
INC RESEARCH HOLDINGS CLASS A | COM | 45329R109 | 665 | 12,636 | SH | SOLE | 0 | 0 | 0 | ||
INCYTE | COM | 45337C102 | 563 | 5,619 | SH | SOLE | 0 | 0 | 0 | ||
INNOCOLL | COM | G4783X105 | 7 | 9,433 | SH | SOLE | 0 | 0 | 0 | ||
INOGEN | COM | 45780L104 | 8 | 125 | SH | SOLE | 0 | 0 | 0 | ||
INTELLIA THERAPEUTICS | COM | 45826J105 | 192 | 14,673 | SH | SOLE | 0 | 0 | 0 | ||
INVITAE | COM | 46185L103 | 3,970 | 500,000 | SH | SOLE | 0 | 0 | 0 | ||
IRHYTHM TECHNOLOGIES | COM | 450056106 | 10,567 | 352,241 | SH | SOLE | 0 | 0 | 0 | ||
IRIDEX | COM | 462684101 | 308 | 21,885 | SH | SOLE | 0 | 0 | 0 | ||
ISHARES 20 PLUS YEAR TREASURY BOND ETF | NOTE | 464287432 | 0 | 2 | PRN | SOLE | 0 | 0 | 0 | ||
ISHARES CORE SandP 500 ETF | COM | 464287200 | 0 | 1 | SH | SOLE | 0 | 0 | 0 | ||
ISHARES RUSSELL MID-CAP VALUE ETF | COM | 464287473 | 0 | 2 | SH | SOLE | 0 | 0 | 0 | ||
JAZZ PHARMACEUTICALS | COM | G50871105 | 5,670 | 52,000 | SH | SOLE | 0 | 0 | 0 | ||
JOHNSON and JOHNSON | COM | 478160104 | 0 | 2 | SH | SOLE | 0 | 0 | 0 | ||
KADMON | COM | 48283N106 | 11,821 | 2,209,657 | SH | SOLE | 0 | 0 | 0 | ||
LA JOLLA PHARMACEUTICAL | COM | 503459604 | 23,127 | 1,319,274 | SH | SOLE | 0 | 0 | 0 | ||
LANTHEUS HOLDINGS | COM | 516544103 | 462 | 53,763 | SH | SOLE | 0 | 0 | 0 | ||
LION BIOTECHNOLOGIES INC | COM | 53619R102 | 24,794 | 3,567,553 | SH | SOLE | 0 | 0 | 0 | ||
LHC GROUP | COM | 50187A107 | 217 | 4,745 | SH | SOLE | 0 | 0 | 0 | ||
MAGELLAN HEALTH | COM | 559079207 | 565 | 7,508 | SH | SOLE | 0 | 0 | 0 | ||
MCKESSON | COM | 58155Q103 | 432 | 3,078 | SH | SOLE | 0 | 0 | 0 | ||
MEDICINES CO PUT 32 04/21/2017 | COM | 584688105 | 1,070 | 200,000 | SH | Put | SOLE | 0 | 0 | 0 | |
MERRIMACK PHARMACEUTICALS | COM | 590328100 | 200 | 48,910 | SH | SOLE | 0 | 0 | 0 | ||
METASTAT INC | COM | 59140A203 | 618 | 500,000 | SH | SOLE | 0 | 0 | 0 | ||
MGC DIAGNOSTICS | COM | 552768103 | 2,602 | 329,733 | SH | SOLE | 0 | 0 | 0 | ||
MINERVA NEUROSCIENCES INC | COM | 603380106 | 9,523 | 810,537 | SH | SOLE | 0 | 0 | 0 | ||
MIRATI THERAPEUTICS | COM | 60468T105 | 2 | 521 | SH | SOLE | 0 | 0 | 0 | ||
MOLINA HEALTHCARE | COM | 60855R100 | 379 | 6,981 | SH | SOLE | 0 | 0 | 0 | ||
MYOKARDIA | COM | 62857M105 | 8,089 | 624,694 | SH | SOLE | 0 | 0 | 0 | ||
MYOVANT SCIENCES | COM | G637AM102 | 2,815 | 226,322 | SH | SOLE | 0 | 0 | 0 | ||
NEOS THERAPEUTICS | COM | 64052L106 | 6 | 1,056 | SH | SOLE | 0 | 0 | 0 | ||
NEPTUNE TECHNOLOGIES AND BIORESOURCES | COM | 64077P108 | 6,004 | 6,519,634 | SH | SOLE | 0 | 0 | 0 | ||
NEUROCRINE BIOSCIENCES | COM | 64125C109 | 128,349 | 3,316,523 | SH | SOLE | 0 | 0 | 0 | ||
NEURODERM | COM | M74231107 | 1,284 | 57,825 | SH | SOLE | 0 | 0 | 0 | ||
NIVALIS THERAPEUTICS | COM | 65481J109 | 274 | 122,275 | SH | SOLE | 0 | 0 | 0 | ||
NOVAVAX | COM | 670002104 | 423 | 335,413 | SH | SOLE | 0 | 0 | 0 | ||
NXSTAGE MEDICAL | COM | 67072V103 | 50,533 | 1,927,989 | SH | SOLE | 0 | 0 | 0 | ||
ONCOBIOLOGICS | COM | 68235M105 | 3,759 | 1,248,990 | SH | SOLE | 0 | 0 | 0 | ||
ONCOBIOLOGICS INC WTS | W EXP 2/18/2017 | 68235M121 | 518 | 656,382 | SH | SOLE | 0 | 0 | 0 | ||
ONCOBIOLOGICS INC WTS | W EXP 2/18/2017 | 68235M113 | 124 | 656,382 | SH | SOLE | 0 | 0 | 0 | ||
OPHTHOTECH CORP CALL 55 01/20/2017 | COM | 683745103 | 0 | 20,000 | SH | Call | SOLE | 0 | 0 | 0 | |
OPHTHOTECH CORP CALL 70 01/20/2017 | COM | 683745103 | 0 | 400 | SH | Call | SOLE | 0 | 0 | 0 | |
OPHTHOTECH CORP CALL 75 01/20/2017 | COM | 683745103 | 5 | 200,000 | SH | Call | SOLE | 0 | 0 | 0 | |
OPHTHOTECH CORP PUT 20 01/20/2017 | COM | 683745103 | 24 | 1,600 | SH | Put | SOLE | 0 | 0 | 0 | |
PEREGRINE PHARMACEUTICALS | COM | 713661304 | 8 | 24,332 | SH | SOLE | 0 | 0 | 0 | ||
PEREGRINE PHARMACEUTICALS INC 10.5 | COM | 713661403 | 3,982 | 200,000 | SH | SOLE | 0 | 0 | 0 | ||
PERNIX THERAPEUTICS HOLD 01APR21 4.25PCT | Note | 71426VAK4 | 246 | 1,000,000 | PRN | SOLE | 0 | 0 | 0 | ||
PFENEX | COM | 717071104 | 8,293 | 914,376 | SH | SOLE | 0 | 0 | 0 | ||
PFIZER | COM | 717081103 | 1,786 | 55,000 | SH | SOLE | 0 | 0 | 0 | ||
PHASERX | COM | 71723F103 | 310 | 200,000 | SH | SOLE | 0 | 0 | 0 | ||
PROTEON THERAPEUTICS | COM | 74371L109 | 635 | 334,116 | SH | SOLE | 0 | 0 | 0 | ||
PSIVIDA | COM | 74440J101 | 3,898 | 2,279,706 | SH | SOLE | 0 | 0 | 0 | ||
PSYCHEMEDICS | COM | 744375205 | 164 | 6,626 | SH | SOLE | 0 | 0 | 0 | ||
PUMA BIOTECHNOLOGY | COM | 74587V107 | 225 | 7,344 | SH | SOLE | 0 | 0 | 0 | ||
QUORUM HEALTH | COM | 74909e106 | 731 | 100,604 | SH | SOLE | 0 | 0 | 0 | ||
QUOTIENT | COM | G73268107 | 13,815 | 2,854,486 | SH | SOLE | 0 | 0 | 0 | ||
RA PHARMACEUTICALS | COM | 74933V108 | 2,506 | 165,000 | SH | SOLE | 0 | 0 | 0 | ||
RADIUS HEALTH | COM | 750469207 | 10,035 | 263,872 | SH | SOLE | 0 | 0 | 0 | ||
REGENXBIO | COM | 75901B107 | 23,786 | 1,282,286 | SH | SOLE | 0 | 0 | 0 | ||
RETROPHIN | COM | 761299106 | 50,872 | 2,687,412 | SH | SOLE | 0 | 0 | 0 | ||
SANGAMO BIOSCIENCES | COM | 800677106 | 1 | 272 | SH | SOLE | 0 | 0 | 0 | ||
SAREPTA THERAPEUTICS | COM | 803607100 | 75,976 | 2,769,829 | SH | SOLE | 0 | 0 | 0 | ||
SAREPTA THERAPEUTICS INC PUT 50 01/20/2017 | COM | 803607100 | 249 | 10,900 | SH | Put | SOLE | 0 | 0 | 0 | |
SCYNEXIS | COM | 811292101 | 546 | 171,185 | SH | SOLE | 0 | 0 | 0 | ||
SELECTA BIOSCIENCES | COM | 816212104 | 2,433 | 141,875 | SH | SOLE | 0 | 0 | 0 | ||
SEVION THERAPEUTICS INC | COM | 81834Q104 | 8 | 59,220 | SH | SOLE | 0 | 0 | 0 | ||
SPDR DOW JONES INDUSTRIAL AVERAGE ETF | COM | 78467X109 | 1 | 3 | SH | SOLE | 0 | 0 | 0 | ||
SPDR GOLD SHARES ETF | COM | 78463V107 | 0 | 1 | SH | SOLE | 0 | 0 | 0 | ||
SPDR SandP BIOTECH ETF | COM | 78464A870 | 3 | 50 | SH | SOLE | 0 | 0 | 0 | ||
STEMLINE THERAPEUTICS | COM | 85858C107 | 115 | 10,702 | SH | SOLE | 0 | 0 | 0 | ||
SUCAMPO PHARMACEUTICALS CLASS A | COM | 864909106 | 416 | 30,694 | SH | SOLE | 0 | 0 | 0 | ||
SUPERNUS PHARMACEUTICALS | COM | 868459108 | 11 | 421 | SH | SOLE | 0 | 0 | 0 | ||
SYNERGY PHARMACEUTICALS | COM | 871639308 | 2,986 | 490,300 | SH | SOLE | 0 | 0 | 0 | ||
TENGION INC | COM | 88034G208 | 1 | 1,826,399 | SH | SOLE | 0 | 0 | 0 | ||
TESARO | COM | 881569107 | 92,521 | 687,993 | SH | SOLE | 0 | 0 | 0 | ||
THERAPEUTICSMD | COM | 88338N107 | 1,731 | 300,000 | SH | SOLE | 0 | 0 | 0 | ||
THERMO FISHER SCIENTIFIC | COM | 883556102 | 0 | 2 | SH | SOLE | 0 | 0 | 0 | ||
TRACON PHARMACEUTICALS | COM | 89237H100 | 490 | 100,000 | SH | SOLE | 0 | 0 | 0 | ||
UNIQURE | COM | N90064101 | 7,089 | 1,265,963 | SH | SOLE | 0 | 0 | 0 | ||
UNITED THERAPEUTICS | COM | 91307C102 | 682 | 4,753 | SH | SOLE | 0 | 0 | 0 | ||
UNITEDHEALTH GROUP | COM | 91324P102 | 516 | 3,223 | SH | SOLE | 0 | 0 | 0 | ||
VBI VACCINES | COM | 91822J103 | 20,354 | 6,565,843 | SH | SOLE | 0 | 0 | 0 | ||
VERICEL | COM | 92346J108 | 28 | 9,385 | SH | SOLE | 0 | 0 | 0 | ||
VERSARTIS | COM | 92529L102 | 61,889 | 4,153,685 | SH | SOLE | 0 | 0 | 0 | ||
VERTEX PHARMACEUTICALS | COM | 92532F100 | 6,299 | 85,509 | SH | SOLE | 0 | 0 | 0 | ||
WAVE LIFE SCIENCES | COM | Y95308105 | 18,088 | 665,198 | SH | SOLE | 0 | 0 | 0 | ||
WELLCARE HEALTHCARE PLANS | COM | 94946T106 | 693 | 5,056 | SH | SOLE | 0 | 0 | 0 | ||
WEST PHARMACEUTICAL SERVICES | COM | 955306105 | 12 | 138 | SH | SOLE | 0 | 0 | 0 | ||
XENCOR | COM | 98401F105 | 46,982 | 1,785,018 | SH | SOLE | 0 | 0 | 0 | ||
XENON PHARMACEUTICALS | COM | 98420N105 | 5,700 | 740,272 | SH | SOLE | 0 | 0 | 0 | ||
ZOETIS CLASS A | COM | 98978V103 | 0 | 3 | SH | SOLE | 0 | 0 | 0 | ||
ZOGENIX | COM | 98978L204 | 9,149 | 752,999 | SH | SOLE | 0 | 0 | 0 | ||
ZYNERBA PHARMACEUTICALS | COM | 98986X109 | 13,128 | 842,128 | SH | SOLE | 0 | 0 | 0 |