Luna Innovations (LUNA) 8-K Changes in Registrant's Certifying Accountant

Ex. 16.1 GT.COM Grant Thornton LLP is the U.S. member firm of Grant Thornton International Ltd (GTIL). GTIL and each of its member firms are separate legal entities and are not a worldwide partnership. GRANT THORNTON LLP 2001 Market St., Suite 700 Philadelphia, PA 19103-7065 D +1 215 561 4200 F +1 215 561 1066 Re: Luna Innovations Incorporated File No. 000-52008 Dear Sir or Madam: We have read Item 4.01 of Form 8-K of Luna Innovations Incorporated dated March 17, 2022, and agree with the statements concerning our Firm contained therein. Very truly yours, /s/ GRANT THORNTON LLP March 23, 2022 U.S. Securities and Exchange Commission Office of the Chief Accountant 100 F Street, NE Washington, DC 20549