MedAssets (MDAS) 8-K Changes in Registrant's Certifying Accountant

Exhibit 16.1

	BDO Seidman, LLP	1100 Peachtree Street, Suite 700
	Accountants and Consultants	Atlanta, Georgia 30309-4516
		Telephone: (404) 688-6841
		Fax: (404) 688-1075

March 8, 2010

Securities and Exchange Commission
100 F Street N.E.
Washington, D.C. 20549

We have been furnished with a copy of the response to Item 4.01 of Form 8-K for the event that occurred on March 2, 2010, to be filed by our former client, MedAssets, Inc. We agree with the statements made in response to that Item insofar as they relate to our Firm.

Very truly yours,

cc: Mr. Bruce F. Wesson, Audit Committee Chair
Mr. John A. Bardis, President
Mr. L. Neil Hunn, Chief Financial Officer
MedAssets, Inc.
100 North Point Center East, Suite 200
Alpharetta, Georgia 30022