Oncternal Therapeutics (ONCT) 10-Q 2009 Q2 Quarterly report

Exhibit 12.1

GTx, Inc.
Computation of Deficiency of Earnings Available to Cover Fixed Charges

	Six Months Ended			Year Ended December 31,
	June 30, 2009			2008			2007			2006			2005			2004
Loss:
Pretax loss from continuing operations	$	(22,561	)	$	(51,780	)	$	(40,359	)	$	(35,510	)	$	(36,839	)	$	(22,348	)
Fixed charges (from below)		51			89			35			32			32			21
Total loss	$	(22,510	)	$	(51,691	)	$	(40,324	)	$	(35,478	)	$	(36,807	)	$	(22,327	)
Fixed charges:
Estimated interest portion of rent expenses	$	51		$	89		$	35		$	32		$	32		$	21
Total fixed charges	$	51		$	89		$	35		$	32		$	32		$	21
Coverage deficiency	$	(22,561	)	$	(51,780	)	$	(40,359	)	$	(35,510	)	$	(36,839	)	$	(22,348	)