| GTx, Inc. | ||
| Computation of Deficiency of Earnings Available to Cover Fixed Charges | ||
| (unaudited — $ in thousands) |
| Nine Months | ||||||||||||||||||||||||
| Ended | ||||||||||||||||||||||||
| September 30, | Year Ended December 31, | |||||||||||||||||||||||
| 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | |||||||||||||||||||
| Loss: | ||||||||||||||||||||||||
| Pretax loss from continuing operations | $ | (27,569 | ) | $ | (35,510 | ) | $ | (36,839 | ) | $ | (22,348 | ) | $ | (14,194 | ) | $ | (11,866 | ) | ||||||
| Fixed charges (from below) | 27 | 32 | 32 | 21 | 18 | 16 | ||||||||||||||||||
| Total loss | $ | (27,542 | ) | $ | (35,478 | ) | $ | (36,807 | ) | $ | (22,327 | ) | $ | (14,176 | ) | $ | (11,850 | ) | ||||||
| Fixed charges: | ||||||||||||||||||||||||
| Estimated interest portion of rent expenses | $ | 27 | $ | 32 | $ | 32 | $ | 21 | $ | 18 | $ | 16 | ||||||||||||
| Total fixed charges | $ | 27 | $ | 32 | $ | 32 | $ | 21 | $ | 18 | $ | 16 | ||||||||||||
| Coverage deficiency | $ | (27,569 | ) | $ | (35,510 | ) | $ | (36,839 | ) | $ | (22,348 | ) | $ | (14,194 | ) | $ | (11,866 | ) | ||||||
