RBC CAPITAL MARKETS, LLC
Three World Financial Center, 8th Floor
200 Vesey Street
New York, NY 10281
July 27, 2012
VIA EDGAR
Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
Attention: Jeffrey Riedler, Assistant Director
Re: | Stemline Therapeutics, Inc. |
| Registration Statement on Form S-1, as amended |
| File No. 333-180515 |
Ladies and Gentlemen:
In accordance with Rule 461 of the General Rules and Regulations promulgated under the Securities Act of 1933, as amended (the “Securities Act”), RBC Capital Markets, LLC, as representative of the several underwriters (the “Representative”) hereby joins in the request of Stemline Therapeutics, Inc. (the “Company”) that the effective time of the above-referenced Registration Statement on Form S-1 be accelerated to Tuesday, July 31, 2012, at 4:00 p.m., Eastern Time, or as soon thereafter as practicable.
In connection with this acceleration request and pursuant to Rule 460 under the Securities Act, please be advised that during the period from July 19, 2012 to the date of this letter, the preliminary prospectus, dated July 19, 2012, was distributed as follows:
Underwriters and dealers: | | 125 | |
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Institutional investors: | | 807 | |
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Retail investors and others: | | 1,058 | |
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Total: | | 1,990 | |
The Representative confirms on behalf of itself and the several underwriters that it has complied and will continue to comply with the requirements of Rule 15c2-8 of the Securities Exchange Act of 1934, as amended, in connection with the above-referenced issue.
[Remainder of Page Intentionally Left Blank]
| Very truly yours, |
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| RBC CAPITAL MARKETS, LLC |
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| As Representative of the Several Underwriters |
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| RBC CAPITAL MARKETS, LLC |
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| By: | /s/ Jennifer Caruso |
| | Name: Jennifer Caruso |
| | Title: Director |
[Signature Page to Underwriter Acceleration Request]