| Document and Entity Information Document | Feb. 26, 2020 |
| Cover page. | |
| Document Type | 8-K |
| Document Period End Date | Feb. 26, 2020 |
| Entity Registrant Name | Portola Pharmaceuticals, Inc |
| Entity Incorporation, State or Country Code | DE |
| Entity File Number | 001-35935 |
| Entity Tax Identification Number | 20-0216859 |
| Entity Address, Address Line One | 270 E. Grand Avenue |
| Entity Address, City or Town | South San Francisco |
| Entity Address, State or Province | CA |
| Entity Address, Postal Zip Code | 94080 |
| City Area Code | 650 |
| Local Phone Number | 246-7300 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common Stock |
| Trading Symbol | PTLA |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | false |
| Entity Central Index Key | 0001269021 |
| Amendment Flag | false |
