Janus Henderson (JHG) 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
10X GENOMICS INC	CL A COM	88025U109	5,125	36,192	SH		DFND	9	0	36,192	0
21VIANET GROUP INC	SPONSORED ADS A	90138A103	4,334	124,940	SH		DFND	4	0	124,940	0
3M CO	COM	88579Y101	103,833	594,080	SH		DFND	4,9,10	0	213,725	380,355
4D MOLECULAR THERAPEUTICS IN	COM	35104E100	39,907	1,021,911	SH		DFND	10	0	992,693	29,218
7GC & CO HOLDINGS INC	UNIT 12/23/2025	81786A206	262	25,000	SH		DFND	4	0	25,000	0
908 DEVICES INC	COM	65443P102	4,795	84,190	SH		DFND	10	0	49,193	34,997
ABB LTD	SPONSORED ADR	000375204	762	27,267	SH		DFND	4,10	0	27,267	0
ABBOTT LABS	COM	002824100	1,020,818	9,323,471	SH		DFND	4,9,10	0	9,193,514	129,957
ABBVIE INC	COM	00287Y109	1,964,269	18,332,278	SH		DFND	4,9,10	0	15,414,832	2,917,446
ABCAM PLC	ADS	000380204	22,768	1,056,516	SH		DFND	10	0	817,889	238,627
ABIOMED INC	COM	003654100	22,523	69,472	SH		DFND	4,9	0	48,366	21,106
ACADIA PHARMACEUTICALS INC	COM	004225108	271,735	5,082,912	SH		DFND	9,10	0	4,927,352	155,560
ACCELERON PHARMA INC	COM	00434H108	232,085	1,814,041	SH		DFND	9,10	0	1,754,261	59,780
ACCENTURE PLC IRELAND	SHS CLASS A	G1151C101	1,281,685	4,906,825	SH		DFND	4,9,10	0	4,046,058	860,767
ACCOLADE INC	COM	00437E102	41,847	962,010	SH		DFND	10	0	924,221	37,789
ACI WORLDWIDE INC	COM	004498101	111,615	2,904,362	SH		DFND	4,10	0	2,803,268	101,094
ACM RESEARCH INC	COM CL A	00108J109	1,811	22,290	SH		DFND	10	0	22,290	0
ACTIVISION BLIZZARD INC	COM	00507V109	502,998	5,417,629	SH		DFND	4,9,10	0	4,785,006	632,623
ADAPTIVE BIOTECHNOLOGIES COR	COM	00650F109	419	7,089	SH		DFND	9	0	7,089	0
ADDUS HOMECARE CORP	COM	006739106	379	3,234	SH		DFND	10	0	3,234	0
ADOBE SYSTEMS INCORPORATED	COM	00724F101	3,371,324	6,741,367	SH		DFND	4,9,10	0	6,222,917	518,450
ADVANCE AUTO PARTS INC	COM	00751Y106	2,866	18,196	SH		DFND	4,9	0	18,196	0
ADVANCED MICRO DEVICES INC	COM	007903107	348,033	3,794,956	SH		DFND	4,9,10	0	2,216,665	1,578,291
AEROJET ROCKETDYNE HLDGS INC	COM	007800105	1,353	25,607	SH		DFND	10	0	25,607	0
AES CORP	COM	00130H105	36,636	1,559,001	SH		DFND	4,9	0	1,435,940	123,061
AFLAC INC	COM	001055102	7,286	163,854	SH		DFND	4,9	0	163,517	337
AFYA LTD	CL A COM	G01125106	12,240	484,458	SH		DFND	4	0	484,458	0
AGILENT TECHNOLOGIES INC	COM	00846U101	42,360	357,516	SH		DFND	2,4,9	0	352,198	5,318
AGNC INVT CORP	COM	00123Q104	2,820	180,736	SH		DFND	4,9	0	180,736	0
AGNICO EAGLE MINES LTD	COM	008474108	6,855	97,340	SH		DFND	4,9	0	97,340	0
AIR PRODS & CHEMS INC	COM	009158106	515,938	1,888,358	SH		DFND	4,9,10,11	0	1,412,009	476,349
AIRBNB INC	COM CL A	009066101	49,249	339,352	SH		DFND	4,10	0	274,712	64,640
AKAMAI TECHNOLOGIES INC	COM	00971T101	47,590	453,286	SH		DFND	4,9	0	104,105	349,181
AKERO THERAPEUTICS INC	COM	00973Y108	90,136	3,493,419	SH		DFND	10	0	3,392,289	101,130
ALAMO GROUP INC	COM	011311107	24,496	177,571	SH		DFND	10	0	169,936	7,635
ALARM COM HLDGS INC	COM	011642105	113,489	1,097,042	SH		DFND	10	0	1,051,637	45,405
ALBANY INTL CORP	CL A	012348108	512	6,975	SH		DFND	4,10	0	6,975	0
ALBEMARLE CORP	COM	012653101	3,637	24,656	SH		DFND	4,9,11	0	24,006	650
ALCON AG	ORD SHS	H01301128	27,007	405,657	SH		DFND	4,9	0	275,763	129,894
ALEXANDRIA REAL ESTATE EQ IN	COM	015271109	72,950	409,571	SH		DFND	4,9,10,12	0	387,353	22,218
ALEXION PHARMACEUTICALS INC	COM	015351109	421,404	2,697,186	SH		DFND	4,9,10	0	2,589,827	107,359
ALGONQUIN PWR UTILS CORP	COM	015857105	5,856	355,915	SH		DFND	4,9,11	0	355,915	0
ALIBABA GROUP HLDG LTD	SPONSORED ADS	01609W102	229,699	987,093	SH		DFND	4,9,10,12	0	942,176	44,917
ALIGN TECHNOLOGY INC	COM	016255101	728,775	1,363,804	SH		DFND	4,9,10	0	1,279,446	84,358
ALIGOS THERAPEUTICS INC	COM	01626L105	50,009	1,893,968	SH		DFND	10	0	1,844,934	49,034
ALLEGHANY CORP DEL	COM	017175100	3,238	5,357	SH		DFND	4,9	0	5,357	0
ALLEGIANT TRAVEL CO	COM	01748X102	1,028	5,432	SH		DFND	10	0	5,432	0
ALLEGION PLC	ORD SHS	G0176J109	4,500	38,659	SH		DFND	4,9	0	38,659	0
ALLIANT ENERGY CORP	COM	018802108	436,651	8,473,743	SH		DFND	2,4,9,10	0	8,147,509	326,234
ALLISON TRANSMISSION HLDGS I	COM	01973R101	597	13,850	SH		DFND	10	0	13,850	0
ALLSTATE CORP	COM	020002101	25,725	234,019	SH		DFND	4,9,10	0	222,379	11,640
ALLY FINL INC	COM	02005N100	35,348	991,243	SH		DFND	4,9	0	129,750	861,493
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	11,731	90,255	SH		DFND	4,9,10	0	90,250	5
ALPHABET INC	CAP STK CL A	02079K305	740,253	422,516	SH		DFND	2,4,9,10	0	399,577	22,939
ALPHABET INC	CAP STK CL C	02079K107	4,014,890	2,291,697	SH		DFND	4,9,10	0	2,101,214	190,483
ALTAIR ENGR INC	COM CL A	021369103	133,696	2,297,972	SH		DFND	10	0	2,226,048	71,924
ALTERYX INC	COM CL A	02156B103	2,322	19,066	SH		DFND	10	0	19,066	0
ALTICE USA INC	CL A	02156K103	4,804	126,857	SH		DFND	4,9	0	126,857	0
ALTIMETER GROWTH CORP	UNIT 99/99/9999	G0370L124	101,633	7,817,934	SH		DFND	10	0	7,621,749	196,185
ALTRIA GROUP INC	COM	02209S103	32,795	799,896	SH		DFND	4,9	0	713,262	86,634
ALX ONCOLOGY HLDGS INC	COM	00166B105	135,690	1,628,199	SH		DFND	10	0	1,607,634	20,565
AMAZON COM INC	COM	023135106	7,342,635	2,254,481	SH		DFND	4,9,10	0	2,060,323	194,158
AMBARELLA INC	SHS	G037AX101	86,368	940,218	SH		DFND	4	0	940,218	0
AMCOR PLC	ORD	G0250X107	16,662	1,415,792	SH		DFND	4,9	0	931,929	483,863
AMDOCS LTD	SHS	G02602103	482,473	6,802,093	SH		DFND	4,9,10	0	6,619,601	182,492
AMEDISYS INC	COM	023436108	6,385	21,767	SH		DFND	9,10	0	21,013	754
AMERCO	COM	023586100	26,863	59,174	SH		DFND	4,9,10	0	51,433	7,741
AMEREN CORP	COM	023608102	10,221	130,962	SH		DFND	4,9	0	130,962	0
AMERICAN AIRLS GROUP INC	COM	02376R102	5,115	324,557	SH		DFND	4,9	0	324,557	0
AMERICAN CAMPUS CMNTYS INC	COM	024835100	883	20,645	SH		DFND	4	0	20,645	0
AMERICAN ELEC PWR CO INC	COM	025537101	143,055	1,717,992	SH		DFND	4,9,10	0	1,631,802	86,190
AMERICAN ELEC PWR CO INC	UNIT 08/15/2025	02557T307	1,992	40,000	SH		DFND	10	0	40,000	0
AMERICAN EXPRESS CO	COM	025816109	505,193	4,178,399	SH		DFND	4,9,10	0	4,158,203	20,196
AMERICAN FINL GROUP INC OHIO	COM	025932104	1,656	18,890	SH		DFND	4,9	0	18,890	0
AMERICAN HOMES 4 RENT	CL A	02665T306	1,518	50,610	SH		DFND	4	0	50,610	0
AMERICAN INTL GROUP INC	COM NEW	026874784	38,741	1,023,283	SH		DFND	2,4,9	0	385,385	637,898
AMERICAN TOWER CORP NEW	COM	03027X100	784,556	3,495,666	SH		DFND	4,9,10,12	0	3,203,705	291,961
AMERICAN VANGUARD CORP	COM	030371108	22,257	1,434,063	SH		DFND	2	0	1,434,063	0
AMERICAN WELL CORP	CL A	03044L105	3,097	122,257	SH		DFND	10	0	72,784	49,473
AMERICAN WOODMARK CORPORATIO	COM	030506109	50,687	540,082	SH		DFND	2,10	0	540,082	0
AMERICAN WTR WKS CO INC NEW	COM	030420103	32,922	214,526	SH		DFND	4,9	0	214,526	0
AMERICOLD RLTY TR	COM	03064D108	79,089	2,118,237	SH		DFND	2,4,9,10,12	0	2,076,911	41,326
AMERIPRISE FINL INC	COM	03076C106	5,348	27,522	SH		DFND	4,9	0	27,522	0
AMERIS BANCORP	COM	03076K108	39,022	1,024,995	SH		DFND	2,10	0	1,024,995	0
AMERISOURCEBERGEN CORP	COM	03073E105	38,425	393,059	SH		DFND	4,9	0	262,594	130,465
AMETEK INC	COM	031100100	66,480	549,715	SH		DFND	2,4,9	0	546,830	2,885
AMGEN INC	COM	031162100	269,066	1,170,285	SH		DFND	4,9,10	0	522,345	647,940
AMICUS THERAPEUTICS INC	COM	03152W109	259,701	11,247,208	SH		DFND	10	0	10,889,013	358,195
AMN HEALTHCARE SVCS INC	COM	001744101	3,557	52,113	SH		DFND	4,10	0	52,113	0
AMPHENOL CORP NEW	CL A	032095101	11,784	90,113	SH		DFND	4,9	0	90,113	0
ANALOG DEVICES INC	COM	032654105	229,757	1,555,967	SH		DFND	2,4,9,10	0	1,497,283	58,684
ANGI HOMESERVICES INC	COM CL A	00183L102	136	10,270	SH		DFND	10	0	10,270	0
ANNALY CAPITAL MANAGEMENT IN	COM	035710409	4,572	541,250	SH		DFND	4,9	0	541,250	0
ANNEXON INC	COM	03589W102	22,085	928,251	SH		DFND	10	0	928,251	0
ANSYS INC	COM	03662Q105	14,092	38,744	SH		DFND	4,9	0	38,744	0
ANTERO MIDSTREAM CORP	COM	03676B102	2,037	264,212	SH		DFND	9	0	179,749	84,463
ANTHEM INC	COM	036752103	205,003	638,454	SH		DFND	4,9,10	0	621,357	17,097
ANWORTH MTG ASSET CORP	COM	037347101	255	94,219	SH		DFND	2	0	94,219	0
AON PLC	SHS CL A	G0403H108	941,652	4,457,198	SH		DFND	4,9,10	0	4,360,423	96,775
APACHE CORP	COM	037411105	18,711	1,318,578	SH		DFND	9	0	1,136,740	181,838
APOLLO GLOBAL MGMT INC	COM CL A	03768E105	193,406	3,948,680	SH		DFND	4,9,10	0	3,277,370	671,310
APPFOLIO INC	COM CL A	03783C100	3,693	20,513	SH		DFND	10	0	20,513	0
APPLE HOSPITALITY REIT INC	COM NEW	03784Y200	17,486	1,354,456	SH		DFND	2,9	0	1,353,543	913
APPLE INC	COM	037833100	9,284,252	69,975,440	SH		DFND	4,9,10	0	60,734,150	9,241,290
APPLIED MATLS INC	COM	038222105	155,158	1,798,371	SH		DFND	4,9	0	1,750,861	47,510
APTARGROUP INC	COM	038336103	2,886	21,086	SH		DFND	9	0	19,062	2,024
APTIV PLC	SHS	G6095L109	388,851	2,984,554	SH		DFND	2,4,9,10	0	2,928,474	56,080
ARAMARK	COM	03852U106	373,425	9,704,383	SH		DFND	4,9,10	0	9,494,715	209,668
ARCH CAP GROUP LTD	ORD	G0450A105	6,359	176,277	SH		DFND	4,9	0	176,277	0
ARCHER DANIELS MIDLAND CO	COM	039483102	106,213	2,107,008	SH		DFND	4,9,10,11	0	1,673,484	433,524
ARDELYX INC	COM	039697107	2,184	337,333	SH		DFND	10	0	337,333	0
ARENA PHARMACEUTICALS INC	COM NEW	040047607	3,787	49,257	SH		DFND	10	0	49,257	0
ARGENX SE	SPONSORED ADR	04016X101	88,996	302,621	SH		DFND	10	0	294,303	8,318
ARGO GROUP INTL HLDGS LTD	COM	G0464B107	48,400	1,107,544	SH		DFND	2	0	1,107,544	0
ARISTA NETWORKS INC	COM	040413106	22,920	78,880	SH		DFND	4,9	0	38,974	39,906
ARROW ELECTRS INC	COM	042735100	1,467	15,079	SH		DFND	4,9	0	15,079	0
ARROWHEAD PHARMACEUTICALS IN	COM	04280A100	87,890	1,145,443	SH		DFND	10	0	1,102,000	43,443
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	501,805	3,008,829	SH		DFND	10	0	2,868,890	139,939
ASGN INC	COM	00191U102	543	6,501	SH		DFND	10	0	6,501	0
ASML HOLDING N V	N Y REGISTRY SHS	N07059210	534,152	1,095,223	SH		DFND	10	0	1,046,162	49,061
ASPEN TECHNOLOGY INC	COM	045327103	3,112	23,892	SH		DFND	10	0	23,892	0
ASSETMARK FINL HLDGS INC	COM	04546L106	16,174	668,344	SH		DFND	4,10	0	641,221	27,123
ASSURANT INC	COM	04621X108	36,731	269,643	SH		DFND	4,9	0	67,821	201,822
ASSURED GUARANTY LTD	COM	G0585R106	2,531	80,384	SH		DFND	9	0	53,126	27,258
ASTRAZENECA PLC	SPONSORED ADR	046353108	42,052	841,212	SH		DFND	10	0	841,212	0
AT&T INC	COM	00206R102	54,603	1,898,670	SH		DFND	4,9,10	0	1,578,158	320,512
ATHENE HOLDING LTD	CL A	G0684D107	1,080	25,024	SH		DFND	4,9,10	0	24,752	272
ATHIRA PHARMA INC	COM	04746L104	32,297	955,660	SH		DFND	10	0	955,660	0
ATKORE INTL GROUP INC	COM	047649108	406	9,882	SH		DFND	10	0	9,882	0
ATLANTIC UN BANKSHARES CORP	COM	04911A107	91,370	2,773,822	SH		DFND	2,10	0	2,773,822	0
ATLASSIAN CORP PLC	CL A	G06242104	932,361	3,986,682	SH		DFND	4,9,10	0	3,712,242	274,440
ATMOS ENERGY CORP	COM	049560105	4,734	49,612	SH		DFND	4,9	0	44,331	5,281
AUTODESK INC	COM	052769106	687,693	2,252,197	SH		DFND	4,9,10	0	1,909,992	342,205
AUTOHOME INC	SP ADR RP CL A	05278C107	499	5,006	SH		DFND	9	0	5,006	0
AUTOLIV INC	COM	052800109	1,726	18,737	SH		DFND	4,9	0	18,737	0
AUTOMATIC DATA PROCESSING IN	COM	053015103	143,616	815,059	SH		DFND	4,9,10	0	468,525	346,534
AUTOZONE INC	COM	053332102	52,025	43,883	SH		DFND	2,4,9	0	34,864	9,019
AVADEL PHARMACEUTICALS PLC	SPONSORED ADR	05337M104	1,538	229,402	SH		DFND	10	0	229,402	0
AVALARA INC	COM	05338G106	543,101	3,293,569	SH		DFND	4,9,10	0	2,959,734	333,835
AVALONBAY CMNTYS INC	COM	053484101	7,199	44,871	SH		DFND	4,9	0	44,871	0
AVANGRID INC	COM	05351W103	963	21,197	SH		DFND	4,10	0	21,197	0
AVANTOR INC	COM	05352A100	1,238	44,007	SH		DFND	4,9	0	44,007	0
AVERY DENNISON CORP	COM	053611109	70,986	457,685	SH		DFND	4,9,10,11	0	366,700	90,985
AVNET INC	COM	053807103	25,857	736,464	SH		DFND	2	0	736,464	0
AVROBIO INC	COM	05455M100	1,569	112,382	SH		DFND	10	0	112,382	0
AXALTA COATING SYS LTD	COM	G0750C108	37,684	1,319,929	SH		DFND	2,4,9,10	0	1,316,843	3,086
AXIS CAP HLDGS LTD	SHS	G0692U109	46,747	927,713	SH		DFND	2,9	0	871,139	56,574
AXOGEN INC	COM	05463X106	26,944	1,505,232	SH		DFND	10	0	1,444,315	60,917
AXON ENTERPRISE INC	COM	05464C101	170,189	1,388,957	SH		DFND	10	0	1,341,056	47,901
AXSOME THERAPEUTICS INC	COM	05464T104	36,552	448,653	SH		DFND	10	0	433,818	14,835
B2GOLD CORP	COM	11777Q209	9,404	1,681,315	SH		DFND	4,9,11	0	1,681,315	0
BAIDU INC	SPON ADR REP A	056752108	1,028	4,753	SH		DFND	9	0	4,753	0
BAKER HUGHES COMPANY	CL A	05722G100	2,909	139,524	SH		DFND	4,9	0	139,524	0
BALL CORP	COM	058498106	129,868	1,393,713	SH		DFND	4,9,10,11	0	1,372,772	20,941
BANK HAWAII CORP	COM	062540109	42,628	556,356	SH		DFND	2	0	556,356	0
BANK MONTREAL QUE	COM	063671101	11,326	149,045	SH		DFND	4,9	0	149,039	6
BANK NEW YORK MELLON CORP	COM	064058100	8,625	203,239	SH		DFND	4,9,10	0	202,010	1,229
BANK NOVA SCOTIA B C	COM	064149107	14,992	277,626	SH		DFND	4,9	0	277,626	0
BARRICK GOLD CORP	COM	067901108	19,483	856,047	SH		DFND	4,9,11	0	856,047	0
BARRICK GOLD CORP	COM	067901108	283	12,443	SH		DFND	10	0	12,443	0
BARRICK GOLD CORP	COM	067901108	100	4,237	SH		DFND	4	0	4,237	0
BAUSCH HEALTH COS INC	COM	071734107	2,332	112,454	SH		DFND	4,9	0	112,454	0
BAXTER INTL INC	COM	071813109	143,191	1,784,570	SH		DFND	4,9,10	0	1,747,687	36,883
BCE INC	COM NEW	05534B760	3,703	86,625	SH		DFND	4,9	0	86,625	0
BCLS ACQUISITION CORP	COM CL A	G0904B105	1,798	163,044	SH		DFND	10	0	163,044	0
BCTG ACQUISITION CORP	COM	05492W103	1,986	174,535	SH		DFND	10	0	174,535	0
BECTON DICKINSON & CO	COM	075887109	50,454	201,617	SH		DFND	4,9,10	0	101,912	99,705
BELLRING BRANDS INC	COM CL A	079823100	21,189	871,623	SH		DFND	10	0	785,607	86,016
BELLUS HEALTH INC NEW	COM NEW	07987C204	5,635	1,856,737	SH		DFND	10	0	1,856,737	0
BENCHMARK ELECTRS INC	COM	08160H101	35,107	1,299,767	SH		DFND	2	0	1,299,767	0
BENTLEY SYS INC	COM CL B	08265T208	6,342	156,553	SH		DFND	10	0	156,553	0
BERKELEY LTS INC	COM	084310101	5,063	56,629	SH		DFND	10	0	24,200	32,429
BERKLEY W R CORP	COM	084423102	438,623	6,603,783	SH		DFND	4,9,10	0	6,409,153	194,630
BERKSHIRE HATHAWAY INC DEL	CL A	084670108	8,007	23	SH		DFND	4	0	23	0
BERKSHIRE HATHAWAY INC DEL	CL B NEW	084670702	162,048	698,913	SH		DFND	2,4,9,10	0	641,406	57,507
BERRY GLOBAL GROUP INC	COM	08579W103	2,973	52,907	SH		DFND	10	0	52,907	0
BEST BUY INC	COM	086516101	221,755	2,222,220	SH		DFND	4,9,10	0	834,203	1,388,017
BEYOND MEAT INC	COM	08862E109	4,014	32,102	SH		DFND	11	0	32,102	0
BHP GROUP PLC	SPONSORED ADR	05545E209	12,103	228,253	SH		DFND	4	0	228,253	0
BILIBILI INC	SPONS ADS REP Z	090040106	329	3,834	SH		DFND	9	0	3,834	0
BILL COM HLDGS INC	COM	090043100	87,122	638,191	SH		DFND	4,9,10	0	584,500	53,691
BIO RAD LABS INC	CL A	090572207	33,164	56,889	SH		DFND	4,9	0	23,099	33,790
BIOATLA INC	COM	09077B104	44,767	1,316,177	SH		DFND	10	0	1,273,547	42,630
BIOGEN INC	COM	09062X103	27,418	111,997	SH		DFND	4,9	0	79,627	32,370
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	498,682	5,686,942	SH		DFND	4,9,10	0	5,514,725	172,217
BIONTECH SE	SPONSORED ADS	09075V102	748	9,173	SH		DFND	4,10	0	9,173	0
BIO-TECHNE CORP	COM	09073M104	185,667	584,685	SH		DFND	9,10	0	558,401	26,284
BIOTELEMETRY INC	COM	090672106	3,485	48,343	SH		DFND	10	0	48,343	0
BK OF AMERICA CORP	COM	060505104	443,624	14,636,465	SH		DFND	4,9,10	0	14,444,132	192,333
BLACK HILLS CORP	COM	092113109	72,854	1,185,585	SH		DFND	2	0	1,185,585	0
BLACK KNIGHT INC	COM	09215C105	3,145	35,603	SH		DFND	4,9	0	35,603	0
BLACKBAUD INC	COM	09227Q100	177,034	3,075,646	SH		DFND	10	0	2,960,112	115,534
BLACKBERRY LTD	COM	09228F103	537	80,973	SH		DFND	4,9	0	80,973	0
BLACKROCK INC	COM	09247X101	38,080	52,792	SH		DFND	4,9	0	45,044	7,748
BLACKSTONE GROUP INC	COM CL A	09260D107	1,202,175	18,549,192	SH		DFND	4,9,10	0	16,129,634	2,419,558
BMC STK HLDGS INC	COM	05591B109	443	8,261	SH		DFND	10	0	8,261	0
BOEING CO	COM	097023105	24,101	112,614	SH		DFND	4,9	0	112,554	60
BOOKING HOLDINGS INC	COM	09857L108	1,452,825	652,322	SH		DFND	4,9,10	0	626,246	26,076
BOOT BARN HLDGS INC	COM	099406100	308	7,104	SH		DFND	10	0	7,104	0
BOOZ ALLEN HAMILTON HLDG COR	CL A	099502106	11,173	128,162	SH		DFND	4,9	0	71,514	56,648
BORGWARNER INC	COM	099724106	3,306	85,558	SH		DFND	4,9	0	85,558	0
BOSTON BEER INC	CL A	100557107	9,180	9,233	SH		DFND	9	0	7,167	2,066
BOSTON PROPERTIES INC	COM	101121101	3,324	35,174	SH		DFND	4,9	0	35,174	0
BOSTON SCIENTIFIC CORP	COM	101137107	1,723,028	47,928,915	SH		DFND	4,9,10	0	46,523,308	1,405,607
BP PLC	SPONSORED ADR	055622104	3,751	182,810	SH		DFND	2	0	118,609	64,201
BRADY CORP	CL A	104674106	170,611	3,230,045	SH		DFND	10	0	3,085,276	144,769
BRIDGEBIO PHARMA INC	COM	10806X102	126,827	1,783,535	SH		DFND	10	0	1,720,639	62,896
BRIGHAM MINERALS INC	CL A COM	10918L103	1,628	148,125	SH		DFND	2	0	148,125	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	1,441,333	23,237,575	SH		DFND	4,9,10	0	21,936,883	1,300,692
BRISTOL-MYERS SQUIBB CO	RIGHT 99/99/9999	110122157	20,555	29,785,990	SH		DFND	10	0	29,055,780	730,210
BRITISH AMERN TOB PLC	SPONSORED ADR	110448107	281	7,508	SH		DFND	4	0	7,508	0
BROADCOM INC	COM	11135F101	719,773	1,643,547	SH		DFND	4,9	0	1,346,073	297,474
BROADMARK RLTY CAP INC	COM	11135B100	110	10,798	SH		DFND	10	0	10,798	0
BROADRIDGE FINL SOLUTIONS IN	COM	11133T103	971,826	6,343,511	SH		DFND	4,9,10	0	6,106,302	237,209
BROOKDALE SR LIVING INC	COM	112463104	171	38,656	SH		DFND	10	0	38,656	0
BROOKFIELD ASSET MGMT INC	CL A LTD VT SH	112585104	3,313	80,286	SH		DFND	4,10	0	80,286	0
BROOKFIELD ASSET MGMT INC	CL A LTD VT SH	112585104	10,871	263,430	SH		DFND	4,9	0	263,430	0
BROOKS AUTOMATION INC NEW	COM	114340102	95,448	1,406,751	SH		DFND	10	0	1,342,637	64,114
BROWN & BROWN INC	COM	115236101	25,708	542,244	SH		DFND	4,9	0	465,456	76,788
BROWN FORMAN CORP	CL B	115637209	17,855	224,796	SH		DFND	4,9	0	166,289	58,507
BRUKER CORP	COM	116794108	133,725	2,470,442	SH		DFND	4,10	0	2,378,887	91,555
BUILDERS FIRSTSOURCE INC	COM	12008R107	659	16,140	SH		DFND	4,10	0	16,140	0
BUNGE LIMITED	COM	G16962105	74,525	1,136,397	SH		DFND	4,9	0	325,101	811,296
BURLINGTON STORES INC	COM	122017106	348,125	1,331,008	SH		DFND	4,9,10	0	1,304,984	26,024
BWX TECHNOLOGIES INC	COM	05605H100	152,315	2,526,791	SH		DFND	2,9	0	2,526,597	194
C H ROBINSON WORLDWIDE INC	COM NEW	12541W209	79,947	851,685	SH		DFND	4,9	0	416,954	434,731
C4 THERAPEUTICS INC	COM STK	12529R107	40,370	1,297,609	SH		DFND	10	0	1,267,804	29,805
CABLE ONE INC	COM	12685J105	98,244	44,100	SH		DFND	4,9,10	0	38,091	6,009
CABOT OIL & GAS CORP	COM	127097103	20,138	1,236,853	SH		DFND	4,9,11	0	766,928	469,925
CADENCE BANCORPORATION	CL A	12739A100	169	10,281	SH		DFND	10	0	10,281	0
CADENCE DESIGN SYSTEM INC	COM	127387108	354,906	2,601,607	SH		DFND	4,9,10	0	1,916,068	685,539
CAE INC	COM	124765108	80,634	2,912,628	SH		DFND	4,9,10	0	2,797,997	114,631
CAESARS ENTERTAINMENT INC NE	COM	12769G100	259,485	3,493,807	SH		DFND	10	0	3,389,604	104,203
CAL MAINE FOODS INC	COM NEW	128030202	24,056	640,804	SH		DFND	2	0	640,804	0
CALAVO GROWERS INC	COM	128246105	678	9,766	SH		DFND	10	0	9,766	0
CALLAWAY GOLF CO	COM	131193104	557	23,186	SH		DFND	10	0	23,186	0
CAMDEN PPTY TR	SH BEN INT	133131102	57,447	574,927	SH		DFND	2,4,9	0	567,480	7,447
CAMECO CORP	COM	13321L108	879	65,697	SH		DFND	4,9	0	65,697	0
CAMPBELL SOUP CO	COM	134429109	118,186	2,444,379	SH		DFND	4,9,10	0	1,086,801	1,357,578
CANADIAN IMP BK COMM	COM	136069101	292	3,411	SH		DFND	10	0	3,411	0
CANADIAN IMP BK COMM	COM	136069101	10,866	127,307	SH		DFND	4,9	0	116,303	11,004
CANADIAN NAT RES LTD	COM	136385101	56,563	2,355,555	SH		DFND	4,9,10	0	1,786,937	568,618
CANADIAN NAT RES LTD	COM	136385101	85,690	3,562,994	SH		DFND	10	0	3,554,021	8,973
CANADIAN NATL RY CO	COM	136375102	18,007	164,062	SH		DFND	4,9	0	164,062	0
CANADIAN PAC RY LTD	COM	13645T100	14,298	41,288	SH		DFND	4,9,10	0	41,288	0
CANOPY GROWTH CORP	COM	138035100	1,391	56,529	SH		DFND	4,9	0	56,529	0
CANTEL MED CORP	COM	138098108	89,801	1,138,743	SH		DFND	10	0	1,101,122	37,621
CAPITAL ONE FINL CORP	COM	14040H105	96,899	980,266	SH		DFND	4,9,10	0	980,266	0
CARDIFF ONCOLOGY INC	COM	14147L108	38,434	2,137,671	SH		DFND	10	0	2,084,762	52,909
CARDINAL HEALTH INC	COM	14149Y108	113,901	2,126,605	SH		DFND	4,9	0	477,477	1,649,128
CARDIOVASCULAR SYS INC DEL	COM	141619106	59,921	1,369,311	SH		DFND	10	0	1,338,955	30,356
CARETRUST REIT INC	COM	14174T107	1,082	48,794	SH		DFND	10	0	48,794	0
CARGURUS INC	COM CL A	141788109	527	16,612	SH		DFND	10	0	16,612	0
CARLISLE COS INC	COM	142339100	161,638	1,034,944	SH		DFND	2,9,10	0	1,006,346	28,598
CARLYLE GROUP INC	COM	14316J108	7,700	244,924	SH		DFND	4,9	0	145,805	99,119
CARMAX INC	COM	143130102	390,145	4,130,282	SH		DFND	4,9,10	0	4,018,666	111,616
CARNIVAL PLC	ADR	14365C103	9,856	526,366	SH		DFND	4	0	526,366	0
CARRIER GLOBAL CORPORATION	COM	14448C104	30,679	813,355	SH		DFND	4,9,10	0	373,263	440,092
CARTERS INC	COM	146229109	73,343	779,660	SH		DFND	2,10	0	770,530	9,130
CARVANA CO	CL A	146869102	13,384	55,872	SH		DFND	4,9	0	36,167	19,705
CASEYS GEN STORES INC	COM	147528103	212,576	1,190,101	SH		DFND	2,9,10	0	1,166,244	23,857
CASS INFORMATION SYS INC	COM	14808P109	18,878	485,175	SH		DFND	2	0	485,175	0
CASTLE BIOSCIENCES INC	COM	14843C105	1,887	28,095	SH		DFND	10	0	28,095	0
CATALENT INC	COM	148806102	1,243,166	11,945,488	SH		DFND	4,9,10	0	11,491,178	454,310
CATERPILLAR INC	COM	149123101	37,418	205,611	SH		DFND	4,9,10	0	205,611	0
CAVCO INDS INC DEL	COM	149568107	397	2,261	SH		DFND	10	0	2,261	0
CBOE GLOBAL MKTS INC	COM	12503M108	279,667	3,003,320	SH		DFND	4,9,10	0	2,931,755	71,565
CBRE GROUP INC	CL A	12504L109	194,079	3,094,353	SH		DFND	4,9,10	0	3,094,353	0
CDK GLOBAL INC	COM	12508E101	104,455	2,015,342	SH		DFND	2	0	2,015,342	0
CDW CORP	COM	12514G108	104,704	794,937	SH		DFND	4,9	0	794,937	0
CELANESE CORP DEL	COM	150870103	46,319	356,458	SH		DFND	4,9	0	55,361	301,097
CENOVUS ENERGY INC	COM	15135U109	1,917	316,319	SH		DFND	4,9	0	316,319	0
CENTENE CORP DEL	COM	15135B101	189,781	3,161,442	SH		DFND	4,9,10	0	3,057,069	104,373
CENTERPOINT ENERGY INC	COM	15189T107	5,461	252,389	SH		DFND	2,4,9	0	252,389	0
CENTURY CASINOS INC	COM	156492100	14,671	2,296,002	SH		DFND	2	0	2,296,002	0
CERIDIAN HCM HLDG INC	COM	15677J108	589,425	5,531,394	SH		DFND	4,9,10	0	5,135,914	395,480
CERNER CORP	COM	156782104	54,737	697,478	SH		DFND	2,4,9,10	0	629,143	68,335
CERTARA INC	COM	15687V109	40,076	1,188,508	SH		DFND	10	0	1,163,256	25,252
CF INDS HLDGS INC	COM	125269100	2,515	64,977	SH		DFND	4,9	0	64,977	0
CGI INC	CL A SUB VTG	12532H104	5,629	71,008	SH		DFND	4,9	0	71,008	0
CHANNELADVISOR CORP	COM	159179100	36,742	2,299,243	SH		DFND	10	0	2,142,738	156,505
CHARTER COMMUNICATIONS INC N	CL A	16119P108	242,389	366,390	SH		DFND	4,9,10	0	238,447	127,943
CHASE CORP	COM	16150R104	11,673	115,559	SH		DFND	10	0	115,559	0
CHECK POINT SOFTWARE TECH LT	ORD	M22465104	47,055	354,033	SH		DFND	2,4,9	0	347,426	6,607
CHEGG INC	COM	163092109	76,302	844,658	SH		DFND	4,9	0	815,293	29,365
CHEMED CORP NEW	COM	16359R103	102,429	192,314	SH		DFND	4,10	0	184,494	7,820
CHENIERE ENERGY INC	COM NEW	16411R208	46,752	778,758	SH		DFND	4,9,10	0	760,294	18,464
CHEVRON CORP NEW	COM	166764100	65,404	774,542	SH		DFND	2,4,9,10	0	597,638	176,904
CHEWY INC	CL A	16679L109	1,710	19,021	SH		DFND	4,9,10	0	13,634	5,387
CHINOOK THERAPEUTICS INC	COM	16961L106	2,746	173,551	SH		DFND	10	0	173,551	0
CHIPOTLE MEXICAN GRILL INC	COM	169656105	98,314	70,895	SH		DFND	4,9	0	47,539	23,356
CHOICE HOTELS INTL INC	COM	169905106	688	6,444	SH		DFND	10	0	6,444	0
CHUBB LIMITED	COM	H1467J104	29,182	189,629	SH		DFND	2,4,9	0	164,607	25,022
CHURCH & DWIGHT INC	COM	171340102	19,970	228,949	SH		DFND	4,9	0	225,282	3,667
CHURCHILL DOWNS INC	COM	171484108	52,248	268,227	SH		DFND	4,10	0	257,562	10,665
CIENA CORP	COM NEW	171779309	102,872	1,947,021	SH		DFND	4,9,10	0	1,946,242	779
CIGNA CORP NEW	COM	125523100	13,369	64,192	SH		DFND	4	0	64,192	0
CIMPRESS PLC	SHS EURO	G2143T103	293,997	3,350,779	SH		DFND	10	0	3,253,011	97,768
CINCINNATI FINL CORP	COM	172062101	45,379	519,409	SH		DFND	4,9	0	472,207	47,202
CINTAS CORP	COM	172908105	148,605	420,445	SH		DFND	4,9	0	120,268	300,177
CISCO SYS INC	COM	17275R102	579,420	12,949,260	SH		DFND	2,4,9	0	7,841,620	5,107,640
CITIGROUP INC	COM NEW	172967424	314,922	5,107,419	SH		DFND	2,4,9,10	0	4,884,030	223,389
CITIZENS FINL GROUP INC	COM	174610105	81,821	2,288,060	SH		DFND	2,4,9	0	2,288,060	0
CITRIX SYS INC	COM	177376100	61,918	475,910	SH		DFND	2,4,9	0	446,576	29,334
CLARIVATE PLC	ORD SHS	G21810109	179,384	6,037,845	SH		DFND	10	0	5,817,912	219,933
CLOROX CO DEL	COM	189054109	188,468	933,382	SH		DFND	4,9,10	0	752,533	180,849
CLOUDFLARE INC	CL A COM	18915M107	6,096	80,228	SH		DFND	4,9	0	71,326	8,902
CMC MATERIALS INC	COM	12571T100	48,260	318,971	SH		DFND	2	0	318,971	0
CME GROUP INC	COM	12572Q105	659,574	3,623,362	SH		DFND	4,9,10	0	3,608,463	14,899
CMS ENERGY CORP	COM	125896100	36,845	603,920	SH		DFND	4,9	0	175,579	428,341
CNH INDL N V	SHS	N20944109	52,037	4,115,160	SH		DFND	4,9	0	3,847,802	267,358
COCA COLA CO	COM	191216100	290,040	5,290,243	SH		DFND	2,4,9,10	0	4,845,497	444,746
COCA COLA EUROPEAN PARTNERS	SHS	G25839104	13,376	268,471	SH		DFND	4,9	0	227,661	40,810
COCA-COLA FEMSA SAB DE CV	SPONSORD ADR REP	191241108	24,322	527,195	SH		DFND	4	0	527,195	0
CODEXIS INC	COM	192005106	31,109	1,425,078	SH		DFND	10	0	1,314,681	110,397
COGENT BIOSCIENCES INC	COM	19240Q201	19,399	1,728,670	SH		DFND	10	0	1,644,154	84,516
COGNEX CORP	COM	192422103	210,361	2,620,180	SH		DFND	4,9,10	0	2,267,484	352,696
COGNIZANT TECHNOLOGY SOLUTIO	CL A	192446102	24,142	294,588	SH		DFND	2,4,9	0	238,396	56,192
COHEN & STEERS INC	COM	19247A100	400	5,377	SH		DFND	2,10	0	5,377	0
COHERUS BIOSCIENCES INC	COM	19249H103	8,795	506,049	SH		DFND	2	0	506,049	0
COLGATE PALMOLIVE CO	COM	194162103	83,773	979,870	SH		DFND	2,4,9	0	615,478	364,392
COLLEGIUM PHARMACEUTICAL INC	COM	19459J104	101,903	5,087,509	SH		DFND	10	0	5,005,518	81,991
COLUMBIA SPORTSWEAR CO	COM	198516106	97,492	1,115,728	SH		DFND	2,9,10	0	1,115,452	276
COMCAST CORP NEW	CL A	20030N101	849,351	16,208,834	SH		DFND	2,4,9,10	0	16,101,487	107,347
COMERICA INC	COM	200340107	931	16,663	SH		DFND	4,9	0	16,663	0
COMFORT SYS USA INC	COM	199908104	43,639	828,685	SH		DFND	2,4,10	0	828,685	0
COMMERCE BANCSHARES INC	COM	200525103	12,571	191,337	SH		DFND	4,9	0	175,073	16,264
COMMERCIAL METALS CO	COM	201723103	60,988	2,969,241	SH		DFND	2	0	2,969,241	0
CONAGRA BRANDS INC	COM	205887102	102,415	2,824,467	SH		DFND	4,9	0	582,455	2,242,012
CONCENTRIX CORP	COM	20602D101	1,795	18,185	SH		DFND	10	0	18,185	0
CONCHO RES INC	COM	20605P101	2,842	48,717	SH		DFND	4,9	0	48,717	0
CONOCOPHILLIPS	COM	20825C104	38,209	955,469	SH		DFND	2,4,9,10	0	897,423	58,046
CONSOLIDATED EDISON INC	COM	209115104	116,552	1,612,742	SH		DFND	4,9,10	0	640,110	972,632
CONSTELLATION BRANDS INC	CL A	21036P108	363,116	1,657,688	SH		DFND	4,9,10	0	1,600,596	57,092
CONSTELLIUM SE	CL A SHS	F21107101	106,036	7,579,444	SH		DFND	10	0	7,579,444	0
CONSTRUCTION PARTNERS INC	COM CL A	21044C107	27,615	948,642	SH		DFND	10	0	914,100	34,542
CONTEXTLOGIC INC	COM CL A	21077C107	31,918	1,750,000	SH		DFND	4,10	0	1,750,000	0
CONTINENTAL RES INC	COM	212015101	1,539	94,389	SH		DFND	9	0	94,389	0
COOPER COS INC	COM NEW	216648402	783,196	2,155,648	SH		DFND	4,9,10	0	2,088,493	67,155
COPART INC	COM	217204106	83,635	657,240	SH		DFND	4,9	0	289,625	367,615
CORCEPT THERAPEUTICS INC	COM	218352102	3,680	140,665	SH		DFND	10	0	140,665	0
CORELOGIC INC	COM	21871D103	2,298	29,719	SH		DFND	4,9	0	14,352	15,367
CORESITE RLTY CORP	COM	21870Q105	4,026	32,140	SH		DFND	9,10	0	27,224	4,916
CORNER GROWTH ACQUISITION CO	UNIT 01/01/2027	G2425N121	261	25,000	SH		DFND	4	0	25,000	0
CORNING INC	COM	219350105	431,293	11,980,099	SH		DFND	4,9,10	0	9,020,437	2,959,662
CORTEVA INC	COM	22052L104	44,382	1,146,200	SH		DFND	2,4,9	0	1,102,934	43,266
COSTAR GROUP INC	COM	22160N109	1,196,074	1,294,046	SH		DFND	4,9,10	0	1,173,381	120,665
COSTCO WHSL CORP NEW	COM	22160K105	783,396	2,079,215	SH		DFND	4,9,10	0	1,953,566	125,649
COUPA SOFTWARE INC	COM	22266L106	5,751	16,978	SH		DFND	4,9	0	16,897	81
COUSINS PPTYS INC	COM NEW	222795502	5,736	171,237	SH		DFND	9	0	90,276	80,961
CRACKER BARREL OLD CTRY STOR	COM	22410J106	51,538	390,675	SH		DFND	2	0	390,675	0
CREDICORP LTD	COM	G2519Y108	2,542	15,495	SH		DFND	4,9	0	15,495	0
CREDIT ACCEP CORP MICH	COM	225310101	344	994	SH		DFND	9,10	0	855	139
CREE INC	COM	225447101	88,115	832,055	SH		DFND	10	0	805,277	26,778
CRITEO S A	SPONS ADS	226718104	39,213	1,914,675	SH		DFND	4	0	1,914,675	0
CROWDSTRIKE HLDGS INC	CL A	22788C105	10,986	51,856	SH		DFND	4,9	0	51,856	0
CROWN CASTLE INTL CORP NEW	COM	22822V101	676,953	4,252,659	SH		DFND	2,4,9,10	0	3,872,769	379,890
CROWN HLDGS INC	COM	228368106	733,798	7,323,332	SH		DFND	4,9,10	0	7,119,174	204,158
CRYOPORT INC	COM PAR $0.001	229050307	42,275	963,414	SH		DFND	10	0	902,346	61,068
CSW INDUSTRIALS INC	COM	126402106	58,776	525,204	SH		DFND	10	0	492,987	32,217
CSX CORP	COM	126408103	293,097	3,229,721	SH		DFND	4,9,10	0	3,209,993	19,728
CUBESMART	COM	229663109	505	15,034	SH		DFND	4,9,10	0	15,034	0
CUBIC CORP	COM	229669106	78,344	1,262,806	SH		DFND	10	0	1,215,483	47,323
CUMMINS INC	COM	231021106	36,857	162,329	SH		DFND	4,9,10	0	116,816	45,513
CVS HEALTH CORP	COM	126650100	247,768	3,627,691	SH		DFND	4,9,10	0	1,538,636	2,089,055
CYBERARK SOFTWARE LTD	SHS	M2682V108	4,384	27,131	SH		DFND	4,9	0	26,059	1,072
CYRUSONE INC	COM	23283R100	10,789	147,486	SH		DFND	9,10	0	75,421	72,065
D R HORTON INC	COM	23331A109	5,809	84,290	SH		DFND	4,9	0	84,192	98
DADA NEXUS LTD	ADS	23344D108	2,825	77,655	SH		DFND	4	0	77,655	0
DANAHER CORPORATION	COM	235851102	1,103,691	4,968,395	SH		DFND	4,9,10	0	4,514,564	453,831
DARDEN RESTAURANTS INC	COM	237194105	100,372	842,606	SH		DFND	4,9	0	217,541	625,065
DATADOG INC	CL A COM	23804L103	3,878	39,394	SH		DFND	4,9	0	39,394	0
DAVE & BUSTERS ENTMT INC	COM	238337109	351	11,681	SH		DFND	10	0	11,681	0
DAVITA INC	COM	23918K108	15,939	135,775	SH		DFND	4,9	0	54,093	81,682
DBX ETF TR	XTRACK HRVST CSI	233051879	867	21,655	SH		DFND	10	0	21,655	0
DECIPHERA PHARMACEUTICALS IN	COM	24344T101	19,109	334,838	SH		DFND	10	0	320,501	14,337
DEERE & CO	COM	244199105	619,193	2,301,448	SH		DFND	4,9,10	0	2,291,432	10,016
DELEK US HLDGS INC NEW	COM	24665A103	34,080	2,120,721	SH		DFND	2	0	2,120,721	0
DELL TECHNOLOGIES INC	CL C	24703L202	4,537	61,897	SH		DFND	4,9,10	0	61,897	0
DELTA AIR LINES INC DEL	COM NEW	247361702	2,618	65,135	SH		DFND	4,9,10	0	63,791	1,344
DENTSPLY SIRONA INC	COM	24906P109	482,056	9,206,575	SH		DFND	4,9,10	0	8,618,630	587,945
DESCARTES SYS GROUP INC	COM	249906108	66,398	1,136,213	SH		DFND	10	0	1,088,292	47,921
DEUTSCHE BANK A G	NAMEN AKT	D18190898	13,148	1,200,787	SH		DFND	4,9	0	285,534	915,253
DEXCOM INC	COM	252131107	229,282	620,147	SH		DFND	4,9,10	0	364,187	255,960
DIAGEO PLC	SPON ADR NEW	25243Q205	447	2,815	SH		DFND	4	0	2,815	0
DIAMONDBACK ENERGY INC	COM	25278X109	4,011	82,865	SH		DFND	4,9,10	0	82,865	0
DIGITAL RLTY TR INC	COM	253868103	59,017	423,031	SH		DFND	4,9,10	0	255,150	167,881
DISCOVER FINL SVCS	COM	254709108	117,050	1,292,943	SH		DFND	2,4,9,10	0	885,055	407,888
DISCOVERY INC	COM SER C	25470F302	12,689	484,556	SH		DFND	4,9	0	483,320	1,236
DISNEY WALT CO	COM	254687106	973,234	5,371,728	SH		DFND	4,9,10	0	4,373,369	998,359
DIVERSIFIED HEALTHCARE TR	COM SH BEN INT	25525P107	209	50,640	SH		DFND	10	0	50,640	0
DOCUSIGN INC	COM	256163106	92,773	417,322	SH		DFND	4,9	0	158,999	258,323
DOLBY LABORATORIES INC	COM CL A	25659T107	320,488	3,299,577	SH		DFND	9,10	0	3,204,946	94,631
DOLLAR GEN CORP NEW	COM	256677105	454,470	2,161,055	SH		DFND	4,9,10	0	2,036,178	124,877
DOLLAR TREE INC	COM	256746108	11,819	109,417	SH		DFND	4,9	0	105,338	4,079
DOMINION ENERGY INC	COM	25746U109	91,806	1,221,193	SH		DFND	4,9,10	0	1,168,471	52,722
DOMINOS PIZZA INC	COM	25754A201	45,099	117,611	SH		DFND	4,9,10	0	84,595	33,016
DONALDSON INC	COM	257651109	117,228	2,097,852	SH		DFND	2,10	0	2,019,695	78,157
DOORDASH INC	CL A	25809K105	173,742	1,217,110	SH		DFND	10	0	1,184,273	32,837
DOUGLAS EMMETT INC	COM	25960P109	31,464	1,077,767	SH		DFND	4,9,10,12	0	997,078	80,689
DOVER CORP	COM	260003108	50,426	399,414	SH		DFND	4,9	0	347,682	51,732
DOW INC	COM	260557103	10,620	191,357	SH		DFND	4,9	0	191,351	6
DRAFTKINGS INC	COM CL A	26142R104	816	17,518	SH		DFND	4,9	0	17,518	0
DRAGONEER GROWTH OPPORTUN CO	UNIT 08/18/2027	G28302126	76,945	5,500,000	SH		DFND	10	0	5,500,000	0
DROPBOX INC	CL A	26210C104	7,991	360,126	SH		DFND	4,9	0	24,619	335,507
DTE ENERGY CO	COM	233331107	68,239	562,143	SH		DFND	4,9	0	562,143	0
DUKE ENERGY CORP NEW	COM NEW	26441C204	21,246	232,087	SH		DFND	4,9,10	0	171,962	60,125
DUKE REALTY CORP	COM NEW	264411505	59,610	1,491,557	SH		DFND	4,9,10,12	0	1,442,814	48,743
DUNE ACQUISITION CORP	UNIT 10/29/2027	265334201	256	25,000	SH		DFND	4	0	25,000	0
DUPONT DE NEMOURS INC	COM	26614N102	28,730	403,988	SH		DFND	2,4,9	0	314,936	89,052
DYNATRACE INC	COM NEW	268150109	304,022	7,026,165	SH		DFND	4,9,10	0	6,340,451	685,714
DYNE THERAPEUTICS INC	COM	26818M108	13,227	629,852	SH		DFND	10	0	607,806	22,046
EAGLE MATLS INC	COM	26969P108	65,448	645,760	SH		DFND	2,9	0	645,382	378
EAGLE PHARMACEUTICALS INC	COM	269796108	78,893	1,694,073	SH		DFND	10	0	1,629,306	64,767
EARGO INC	COM	270087109	13,544	302,194	SH		DFND	10	0	290,164	12,030
EAST WEST BANCORP INC	COM	27579R104	254	5,016	SH		DFND	9	0	3,894	1,122
EASTERLY GOVT PPTYS INC	COM	27616P103	31,865	1,406,836	SH		DFND	10	0	1,306,300	100,536
EASTMAN CHEM CO	COM	277432100	3,441	34,320	SH		DFND	4,9	0	34,320	0
EATON CORP PLC	SHS	G29183103	134,236	1,117,335	SH		DFND	4,9	0	301,442	815,893
EBAY INC.	COM	278642103	138,250	2,751,257	SH		DFND	4,9,10	0	1,235,029	1,516,228
EBIX INC	COM NEW	278715206	1,988	52,344	SH		DFND	10	0	52,344	0
ECOLAB INC	COM	278865100	27,601	127,579	SH		DFND	4,9	0	69,895	57,684
EDISON INTL	COM	281020107	168,976	2,689,868	SH		DFND	4,9	0	1,021,961	1,667,907
EDWARDS LIFESCIENCES CORP	COM	28176E108	888,674	9,741,014	SH		DFND	4,9,10	0	7,244,496	2,496,518
ELANCO ANIMAL HEALTH INC	COM	28414H103	1,069,375	34,867,068	SH		DFND	4,9,10	0	33,806,282	1,060,786
ELECTRONIC ARTS INC	COM	285512109	187,692	1,307,031	SH		DFND	2,4,9	0	905,532	401,499
EMCOR GROUP INC	COM	29084Q100	80,874	884,258	SH		DFND	2,10	0	884,258	0
EMERGENT BIOSOLUTIONS INC	COM	29089Q105	84,588	944,064	SH		DFND	10	0	906,138	37,926
EMERSON ELEC CO	COM	291011104	44,985	559,737	SH		DFND	4,9	0	418,023	141,714
ENBRIDGE INC	COM	29250N105	56,849	1,778,726	SH		DFND	4,9	0	1,572,487	206,239
ENBRIDGE INC	COM	29250N105	2,822	88,219	SH		DFND	4	0	88,219	0
ENCOMPASS HEALTH CORP	COM	29261A100	68,003	822,038	SH		DFND	4,10	0	822,038	0
ENCORE WIRE CORP	COM	292562105	46,330	764,898	SH		DFND	2	0	764,898	0
ENERGIZER HLDGS INC NEW	COM	29272W109	2,091	49,582	SH		DFND	9	0	33,227	16,355
ENERSYS	COM	29275Y102	143,698	1,730,052	SH		DFND	10	0	1,661,918	68,134
ENPHASE ENERGY INC	COM	29355A107	2,552	14,542	SH		DFND	4,9	0	14,542	0
ENSIGN GROUP INC	COM	29358P101	796	10,919	SH		DFND	10	0	10,919	0
ENSTAR GROUP LIMITED	SHS	G3075P101	310	1,515	SH		DFND	10	0	1,515	0
ENTEGRIS INC	COM	29362U104	192,470	2,002,805	SH		DFND	9,10	0	1,916,766	86,039
ENTERGY CORP NEW	COM	29364G103	86,318	864,561	SH		DFND	2,4,9	0	840,549	24,012
ENTERPRISE FINL SVCS CORP	COM	293712105	32,706	935,789	SH		DFND	2,10	0	935,789	0
ENTERPRISE PRODS PARTNERS L	COM	293792107	12,350	630,440	SH		DFND	10	0	630,440	0
ENVESTNET INC	COM	29404K106	183,127	2,225,388	SH		DFND	10	0	2,141,741	83,647
ENVISTA HOLDINGS CORPORATION	COM	29415F104	98,280	2,912,898	SH		DFND	2,4	0	2,912,898	0
EOG RES INC	COM	26875P101	14,366	288,162	SH		DFND	4,9,11	0	288,162	0
EPAM SYS INC	COM	29414B104	4,651	12,979	SH		DFND	4,9	0	12,979	0
EQT CORP	COM	26884L109	3,203	251,985	SH		DFND	9	0	211,685	40,300
EQUIFAX INC	COM	294429105	13,243	68,672	SH		DFND	4,9	0	56,569	12,103
EQUINIX INC	COM	29444U700	459,495	643,416	SH		DFND	4,9,10	0	537,778	105,638
EQUITABLE HLDGS INC	COM	29452E101	15,815	618,035	SH		DFND	4,9	0	221,426	396,609
EQUITY COMWLTH	COM SH BEN INT	294628102	88,608	3,248,102	SH		DFND	2,9	0	3,184,088	64,014
EQUITY LIFESTYLE PPTYS INC	COM	29472R108	137,738	2,174,014	SH		DFND	2,4,9,10,12	0	2,131,097	42,917
EQUITY RESIDENTIAL	SH BEN INT	29476L107	8,744	147,524	SH		DFND	2,4,9	0	130,024	17,500
ERIE INDTY CO	CL A	29530P102	23,295	94,848	SH		DFND	4,9	0	32,825	62,023
ESSA PHARMA INC	COM NEW	29668H708	5,995	509,095	SH		DFND	10	0	509,095	0
ESSENT GROUP LTD	COM	G3198U102	223	5,151	SH		DFND	10	0	5,151	0
ESSENTIAL UTILS INC	COM	29670G102	1,241	26,234	SH		DFND	4,9	0	26,234	0
ESSEX PPTY TR INC	COM	297178105	55,683	234,540	SH		DFND	4,9,10,12	0	226,786	7,754
ETSY INC	COM	29786A106	271,408	1,525,537	SH		DFND	4,9,10	0	1,395,978	129,559
EURONAV NV	SHS	B38564108	15,917	1,990,822	SH		DFND	4	0	1,990,822	0
EURONET WORLDWIDE INC	COM	298736109	418,338	2,886,680	SH		DFND	10	0	2,789,857	96,823
EVERBRIDGE INC	COM	29978A104	32,562	218,435	SH		DFND	9,10	0	206,119	12,316
EVERCORE INC	CLASS A	29977A105	40,804	372,161	SH		DFND	2,9,10	0	371,548	613
EVEREST RE GROUP LTD	COM	G3223R108	90,858	388,134	SH		DFND	4,9	0	190,761	197,373
EVERGY INC	COM	30034W106	80,956	1,458,435	SH		DFND	2,4,9	0	1,344,633	113,802
EVERSOURCE ENERGY	COM	30040W108	36,002	416,169	SH		DFND	4,9	0	202,280	213,889
EVOQUA WATER TECHNOLOGIES CO	COM	30057T105	51,328	1,902,093	SH		DFND	4,10	0	1,902,093	0
EXACT SCIENCES CORP	COM	30063P105	4,405	33,243	SH		DFND	4,9,10	0	24,052	9,191
EXELIXIS INC	COM	30161Q104	17,542	874,031	SH		DFND	9,10	0	832,982	41,049
EXELON CORP	COM	30161N101	35,040	829,950	SH		DFND	2,4,9	0	722,236	107,714
EXLSERVICE HOLDINGS INC	COM	302081104	2,354	27,647	SH		DFND	10	0	27,647	0
EXPEDIA GROUP INC	COM NEW	30212P303	5,521	41,702	SH		DFND	4,9	0	41,469	233
EXPEDITORS INTL WASH INC	COM	302130109	48,879	513,932	SH		DFND	4,9	0	201,870	312,062
EXPONENT INC	COM	30214U102	571	6,346	SH		DFND	10	0	6,346	0
EXTRA SPACE STORAGE INC	COM	30225T102	18,754	161,874	SH		DFND	4,9	0	126,157	35,717
EXXON MOBIL CORP	COM	30231G102	41,753	1,013,156	SH		DFND	2,4,9	0	974,564	38,592
EYEPOINT PHARMACEUTICALS INC	COM NEW	30233G209	136	20,636	SH		DFND	10	0	20,636	0
F5 NETWORKS INC	COM	315616102	64,934	369,063	SH		DFND	2,4,9	0	362,316	6,747
FABRINET	SHS	G3323L100	42,009	541,422	SH		DFND	2	0	541,422	0
FACEBOOK INC	CL A	30303M102	3,410,933	12,487,626	SH		DFND	4,9,10	0	11,082,489	1,405,137
FACTSET RESH SYS INC	COM	303075105	14,101	42,407	SH		DFND	4,9	0	15,700	26,707
FAIR ISAAC CORP	COM	303250104	2,243	4,387	SH		DFND	4,9	0	4,387	0
FASTENAL CO	COM	311900104	344,781	7,060,880	SH		DFND	4,9	0	3,030,606	4,030,274
FASTLY INC	CL A	31188V100	433	4,960	SH		DFND	9	0	4,960	0
FATE THERAPEUTICS INC	COM	31189P102	231,467	2,545,568	SH		DFND	10	0	2,459,642	85,926
FB FINL CORP	COM	30257X104	45,528	1,310,899	SH		DFND	2,10	0	1,310,899	0
FEDERAL RLTY INVT TR	SH BEN INT NEW	313747206	513	6,027	SH		DFND	4	0	6,027	0
FEDEX CORP	COM	31428X106	20,420	78,653	SH		DFND	4,9	0	78,653	0
FERRARI N V	COM	N3167Y103	18,788	81,389	SH		DFND	4,9	0	33,849	47,540
FIAT CHRYSLER AUTOMOBILES N	SHS	N31738102	7,908	440,819	SH		DFND	4,9	0	144,703	296,116
FIBROGEN INC	COM	31572Q808	126,094	3,399,684	SH		DFND	10	0	3,284,948	114,736
FIDELITY NATIONAL FINANCIAL	FNF GROUP COM	31620R303	4,945	126,499	SH		DFND	4,9	0	117,682	8,817
FIDELITY NATL INFORMATION SV	COM	31620M106	1,121,738	7,930,090	SH		DFND	4,9,10	0	7,337,878	592,212
FIFTH THIRD BANCORP	COM	316773100	55,729	2,021,381	SH		DFND	2,4,9	0	1,781,136	240,245
FIRST AMERN FINL CORP	COM	31847R102	75,709	1,466,380	SH		DFND	2	0	1,466,380	0
FIRST FINL BANKSHARES	COM	32020R109	236	6,535	SH		DFND	10	0	6,535	0
FIRST HORIZON CORPORATION	COM	320517105	118,565	9,291,891	SH		DFND	2	0	9,291,891	0
FIRST REP BK SAN FRANCISCO C	COM	33616C100	23,742	161,594	SH		DFND	4,9	0	120,346	41,248
FIRST SOLAR INC	COM	336433107	420	4,248	SH		DFND	9	0	963	3,285
FIRSTENERGY CORP	COM	337932107	26,330	860,192	SH		DFND	4,9	0	757,125	103,067
FIRSTSERVICE CORP NEW	COM	33767E202	30,787	225,116	SH		DFND	10	0	216,177	8,939
FIRSTSERVICE CORP NEW	COM	33767E202	417	3,048	SH		DFND	4,9	0	3,048	0
FISERV INC	COM	337738108	175,622	1,542,945	SH		DFND	4,9	0	1,525,754	17,191
FIVE BELOW INC	COM	33829M101	1,135	6,488	SH		DFND	10	0	6,488	0
FIVE9 INC	COM	338307101	4,259	24,423	SH		DFND	9	0	24,423	0
FLEETCOR TECHNOLOGIES INC	COM	339041105	19,720	72,278	SH		DFND	4,9	0	49,680	22,598
FLEX LNG LTD	SHS	G35947202	24,982	2,849,068	SH		DFND	4	0	2,849,068	0
FLEX LTD	ORD	Y2573F102	401,820	22,348,167	SH		DFND	4,9,10	0	21,722,315	625,852
FLOOR & DECOR HLDGS INC	CL A	339750101	1,753	18,880	SH		DFND	9,10	0	18,880	0
FLOWERS FOODS INC	COM	343498101	3,690	163,039	SH		DFND	9	0	135,972	27,067
FLWS/1-800 FLOWERS	CL A	68243Q106	232	8,932	SH		DFND	10	0	8,932	0
FMC CORP	COM NEW	302491303	37,271	324,295	SH		DFND	4,9,11	0	285,029	39,266
FOCUS FINL PARTNERS INC	COM CL A	34417P100	800	18,363	SH		DFND	4	0	18,363	0
FORD MTR CO DEL	COM	345370860	10,832	1,232,750	SH		DFND	4,9	0	1,200,796	31,954
FORMA THERAPEUTICS HLDGS INC	SHS	34633R104	37,810	1,114,709	SH		DFND	10	0	1,091,990	22,719
FORMFACTOR INC	COM	346375108	2,511	58,368	SH		DFND	4,10	0	58,368	0
FORTINET INC	COM	34959E109	7,807	52,575	SH		DFND	4,9	0	52,575	0
FORTIS INC	COM	349553107	4,784	117,288	SH		DFND	4,9	0	117,288	0
FORTIVE CORP	COM	34959J108	4,329	61,127	SH		DFND	4,9	0	61,127	0
FORTUNA SILVER MINES INC	COM	349915108	683	83,217	SH		DFND	11	0	83,217	0
FORTUNE BRANDS HOME & SEC IN	COM	34964C106	5,671	66,168	SH		DFND	4,9	0	66,168	0
FOX CORP	CL A COM	35137L105	3,173	108,975	SH		DFND	4,9,10	0	107,805	1,170
FOX CORP	CL B COM	35137L204	56,793	1,966,517	SH		DFND	2,4,9	0	1,914,299	52,218
FOX FACTORY HLDG CORP	COM	35138V102	512	4,848	SH		DFND	10	0	4,848	0
FRANCO NEV CORP	COM	351858105	17,097	136,567	SH		DFND	4,9,11	0	130,644	5,923
FRANKLIN RESOURCES INC	COM	354613101	1,233	49,331	SH		DFND	4,9	0	49,331	0
FRANKLIN TEMPLETON ETF TR	FTSE JAPAN ETF	35473P744	14,322	480,928	SH		DFND	10	0	480,928	0
FRANKLIN TEMPLETON ETF TR	FTSE UNTD KGDM	35473P678	25,587	1,145,877	SH		DFND	10	0	1,145,877	0
FREEPORT-MCMORAN INC	CL B	35671D857	126,120	4,847,147	SH		DFND	4,9,10,11	0	4,847,147	0
FRONTDOOR INC	COM	35905A109	315,626	6,286,110	SH		DFND	9,10	0	6,047,356	238,754
FRONTLINE LTD	SHS NEW	G3682E192	695	109,665	SH		DFND	4	0	109,665	0
FTI CONSULTING INC	COM	302941109	2,739	24,516	SH		DFND	9,10	0	15,442	9,074
FULCRUM THERAPEUTICS INC	COM	359616109	2,688	229,634	SH		DFND	10	0	229,634	0
FULLER H B CO	COM	359694106	43,670	841,754	SH		DFND	10	0	798,052	43,702
FULTON FINL CORP PA	COM	360271100	67,363	5,295,818	SH		DFND	2	0	5,295,818	0
GALECTO INC	COM	36322Q107	15,856	1,335,569	SH		DFND	10	0	1,269,204	66,365
GALLAGHER ARTHUR J & CO	COM	363576109	11,534	93,236	SH		DFND	4,9	0	93,236	0
GARMIN LTD	SHS	H2906T109	211,231	1,765,270	SH		DFND	4,9,10	0	1,113,171	652,099
GARTNER INC	COM	366651107	5,476	34,184	SH		DFND	4,9	0	34,184	0
GATES INDUSTRIAL CORPRATIN P	ORD SHS	G39108108	95,011	7,445,976	SH		DFND	10	0	7,180,844	265,132
GATOS SILVER INC	COM	368036109	1,107	84,958	SH		DFND	11	0	84,958	0
GATX CORP	COM	361448103	114,414	1,375,500	SH		DFND	2	0	1,375,500	0
GDS HLDGS LTD	SPONSORED ADS	36165L108	71,167	760,162	SH		DFND	4,9,10,12	0	749,547	10,615
GENERAC HLDGS INC	COM	368736104	13,664	60,086	SH		DFND	2,4,9	0	54,125	5,961
GENERAL DYNAMICS CORP	COM	369550108	342,354	2,300,465	SH		DFND	4,9,10	0	2,299,229	1,236
GENERAL ELECTRIC CO	COM	369604103	17,423	1,613,721	SH		DFND	4,9	0	1,569,895	43,826
GENERAL MLS INC	COM	370334104	149,444	2,541,590	SH		DFND	4,9,10	0	1,089,178	1,452,412
GENERAL MTRS CO	COM	37045V100	139,971	3,361,515	SH		DFND	4,9	0	2,224,433	1,137,082
GENESIS HEALTHCARE INC	CL A COM	37185X106	8	16,204	SH		DFND	10	0	16,204	0
GENPACT LIMITED	SHS	G3922B107	17,334	419,108	SH		DFND	9	0	233,812	185,296
GENTEX CORP	COM	371901109	10,756	316,996	SH		DFND	4,9	0	246,668	70,328
GENUINE PARTS CO	COM	372460105	3,140	31,269	SH		DFND	4,9	0	31,269	0
GEOPARK LTD	USD SHS	G38327105	2,064	158,866	SH		DFND	10	0	158,866	0
GIBRALTAR INDS INC	COM	374689107	488	6,778	SH		DFND	10	0	6,778	0
GILDAN ACTIVEWEAR INC	COM	375916103	246,864	8,813,408	SH		DFND	10	0	8,425,360	388,048
GILDAN ACTIVEWEAR INC	COM	375916103	1,071	38,335	SH		DFND	4,9	0	38,335	0
GILEAD SCIENCES INC	COM	375558103	289,637	4,971,519	SH		DFND	2,4,9,10	0	4,239,742	731,777
GLAUKOS CORP	COM	377322102	117,078	1,555,651	SH		DFND	10	0	1,496,093	59,558
GLAXOSMITHKLINE PLC	SPONSORED ADR	37733W105	288	7,824	SH		DFND	4,10	0	7,824	0
GLOBAL BLOOD THERAPEUTICS IN	COM	37890U108	258,426	5,966,862	SH		DFND	9,10	0	5,775,863	190,999
GLOBAL PMTS INC	COM	37940X102	701,257	3,255,329	SH		DFND	2,4,9,10	0	3,034,220	221,109
GLOBANT S A	COM	L44385109	1,255	5,767	SH		DFND	4,9	0	5,767	0
GLOBE LIFE INC	COM	37959E102	93,616	985,853	SH		DFND	2,4,9	0	985,853	0
GLOBUS MED INC	CL A	379577208	420,132	6,441,759	SH		DFND	2,10	0	6,196,739	245,020
GMS INC	COM	36251C103	432	14,159	SH		DFND	10	0	14,159	0
GODADDY INC	CL A	380237107	572,363	6,900,096	SH		DFND	4,9,10	0	6,713,615	186,481
GOLDEN FALCON ACQUISITION CO	UNIT 99/99/9999	38102H208	209	20,000	SH		DFND	4	0	20,000	0
GOLDMAN SACHS GROUP INC	COM	38141G104	82,905	314,445	SH		DFND	4,9,10	0	241,735	72,710
GOODRX HLDGS INC	COM CL A	38246G108	2,500	61,980	SH		DFND	10	0	61,980	0
GRACE W R & CO DEL NEW	COM	38388F108	32,619	595,014	SH		DFND	2,9	0	583,289	11,725
GRACO INC	COM	384109104	3,412	47,166	SH		DFND	9,10	0	47,166	0
GRAINGER W W INC	COM	384802104	70,399	172,403	SH		DFND	4,9	0	36,474	135,929
GRAPHIC PACKAGING HLDG CO	COM	388689101	59,107	3,489,224	SH		DFND	2,9	0	3,484,050	5,174
GREEN DOT CORP	CL A	39304D102	244	4,366	SH		DFND	10	0	4,366	0
GREENSKY INC	CL A	39572G100	598	129,196	SH		DFND	10	0	129,196	0
GRIFOLS S A	SP ADR REP B NVT	398438408	62,644	3,399,031	SH		DFND	4	0	3,273,380	125,651
GRUBHUB INC	COM	400110102	3,522	47,420	SH		DFND	4	0	0	47,420
GSX TECHEDU INC	SPONSORED ADS	36257Y109	4,200	81,223	SH		DFND	9	0	1,538	79,685
GUARDANT HEALTH INC	COM	40131M109	28,604	221,943	SH		DFND	9	0	124,044	97,899
GUIDEWIRE SOFTWARE INC	COM	40171V100	164,974	1,281,549	SH		DFND	4,9,10	0	1,128,198	153,351
GW PHARMACEUTICALS PLC	ADS	36197T103	227,967	1,975,301	SH		DFND	10	0	1,920,540	54,761
H & E EQUIPMENT SERVICES INC	COM	404030108	47,245	1,584,861	SH		DFND	2	0	1,584,861	0
HACKETT GROUP INC	COM	404609109	153	10,641	SH		DFND	10	0	10,641	0
HAIN CELESTIAL GROUP INC	COM	405217100	24,800	617,673	SH		DFND	10	0	597,137	20,536
HALLIBURTON CO	COM	406216101	62,732	3,319,101	SH		DFND	4,9	0	942,749	2,376,352
HALOZYME THERAPEUTICS INC	COM	40637H109	34,143	799,410	SH		DFND	10	0	764,280	35,130
HANESBRANDS INC	COM	410345102	717	49,167	SH		DFND	9	0	49,167	0
HANOVER INS GROUP INC	COM	410867105	113,191	968,103	SH		DFND	2,9	0	965,932	2,171
HARMONY BIOSCIENCES HLDGS IN	COM	413197104	39,562	1,094,449	SH		DFND	10	0	1,063,587	30,862
HARTFORD FINL SVCS GROUP INC	COM	416515104	127,123	2,595,402	SH		DFND	2,4,9	0	2,425,891	169,511
HASBRO INC	COM	418056107	564,144	6,031,050	SH		DFND	4,9,10	0	5,292,564	738,486
HCA HEALTHCARE INC	COM	40412C101	13,633	82,896	SH		DFND	4,9	0	82,411	485
HDFC BANK LTD	SPONSORED ADS	40415F101	16,632	230,224	SH		DFND	4,10,12	0	169,490	60,734
HEALTH ASSURN ACQUISITION CO	UNIT 99/99/9999	42226W208	11,060	1,003,615	SH		DFND	10	0	971,098	32,517
HEALTH CATALYST INC	COM	42225T107	62,583	1,437,694	SH		DFND	10	0	1,395,903	41,791
HEALTH SCIENCES ACQ CORP 2	ORD SHS	G4411D109	2,180	170,276	SH		DFND	10	0	170,276	0
HEALTHCARE SVCS GROUP INC	COM	421906108	9,679	344,454	SH		DFND	2,10	0	344,454	0
HEALTHCARE TR AMER INC	CL A NEW	42225P501	3,494	126,858	SH		DFND	9	0	64,549	62,309
HEALTHEQUITY INC	COM	42226A107	99,039	1,420,728	SH		DFND	10	0	1,372,659	48,069
HEALTHPEAK PROPERTIES INC	COM	42250P103	13,406	443,493	SH		DFND	4,9,10	0	395,080	48,413
HEICO CORP NEW	CL A	422806208	10,197	87,110	SH		DFND	4,9,10	0	86,377	733
HEICO CORP NEW	COM	422806109	10,063	75,995	SH		DFND	4,9,10	0	54,770	21,225
HELIX ACQUISITION CORP	COM CL A	G4444C102	1,658	150,000	SH		DFND	10	0	150,000	0
HENRY JACK & ASSOC INC	COM	426281101	4,461	27,544	SH		DFND	4,9	0	26,346	1,198
HENRY SCHEIN INC	COM	806407102	40,764	609,692	SH		DFND	2,4,9	0	418,123	191,569
HERBALIFE NUTRITION LTD	COM SHS	G4412G101	244	5,084	SH		DFND	4	0	5,084	0
HERSHEY CO	COM	427866108	329,778	2,164,893	SH		DFND	4,9,10	0	2,021,713	143,180
HESKA CORP	COM RESTRC NEW	42805E306	39,550	271,540	SH		DFND	10	0	265,804	5,736
HESS CORP	COM	42809H107	4,248	80,454	SH		DFND	4,9	0	80,454	0
HEWLETT PACKARD ENTERPRISE C	COM	42824C109	3,805	321,023	SH		DFND	4,9	0	321,023	0
HEXCEL CORP NEW	COM	428291108	1,377	28,393	SH		DFND	4,10	0	28,393	0
HILTON WORLDWIDE HLDGS INC	COM	43300A203	306,989	2,759,179	SH		DFND	4,9,10	0	2,519,812	239,367
HOLOGIC INC	COM	436440101	64,538	886,133	SH		DFND	4,9	0	89,002	797,131
HOME DEPOT INC	COM	437076102	985,888	3,711,823	SH		DFND	4,9,10	0	3,654,069	57,754
HONEYWELL INTL INC	COM	438516106	1,004,034	4,720,483	SH		DFND	2,4,9,10	0	4,363,336	357,147
HORIZON BANCORP INC	COM	440407104	21,146	1,333,272	SH		DFND	2,10	0	1,333,272	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	599,294	8,192,621	SH		DFND	4,9,10	0	7,924,484	268,137
HORMEL FOODS CORP	COM	440452100	69,087	1,482,242	SH		DFND	4,9,10	0	639,474	842,768
HOST HOTELS & RESORTS INC	COM	44107P104	42,984	2,938,112	SH		DFND	4,9	0	568,041	2,370,071
HOSTESS BRANDS INC	CL A	44109J106	88,243	6,027,516	SH		DFND	10	0	5,802,974	224,542
HOULIHAN LOKEY INC	CL A	441593100	237	3,519	SH		DFND	4,10	0	3,519	0
HOWARD HUGHES CORP	COM	44267D107	207	2,628	SH		DFND	9	0	567	2,061
HOWMET AEROSPACE INC	COM	443201108	3,242	113,605	SH		DFND	4,9,10	0	112,101	1,504
HP INC	COM	40434L105	287,652	11,697,991	SH		DFND	4,9	0	4,780,759	6,917,232
HUAZHU GROUP LTD	SPONSORED ADS	44332N106	848	18,838	SH		DFND	9	0	18,838	0
HUBBELL INC	COM	443510607	8,035	51,246	SH		DFND	9	0	25,084	26,162
HUBSPOT INC	COM	443573100	17,062	43,038	SH		DFND	4,9,10	0	30,144	12,894
HUDBAY MINERALS INC	COM	443628102	745	106,488	SH		DFND	11	0	106,488	0
HUMANA INC	COM	444859102	750,021	1,828,264	SH		DFND	2,4,9,10	0	1,765,931	62,333
HUNT J B TRANS SVCS INC	COM	445658107	283,523	2,074,806	SH		DFND	4,9,10	0	2,014,597	60,209
HUNTINGTON BANCSHARES INC	COM	446150104	3,072	243,320	SH		DFND	4,9	0	243,320	0
HUNTINGTON INGALLS INDS INC	COM	446413106	3,227	18,928	SH		DFND	4,9	0	18,928	0
HUNTSMAN CORP	COM	447011107	3,241	128,922	SH		DFND	9	0	128,922	0
HYDROFARM HLDGS GROUP INC	COM	44888K209	17,078	324,805	SH		DFND	10	0	312,210	12,595
IAA INC	COM	449253103	174,167	2,680,320	SH		DFND	2,9,10	0	2,606,474	73,846
IAC INTERACTIVECORP NEW	COM	44891N109	204,412	1,079,036	SH		DFND	4,9	0	1,015,795	63,241
ICON PLC	SHS	G4705A100	93,105	477,309	SH		DFND	4,10	0	471,488	5,821
ICU MED INC	COM	44930G107	562,756	2,623,694	SH		DFND	9,10	0	2,546,523	77,171
IDEX CORP	COM	45167R104	3,466	17,398	SH		DFND	4,9	0	17,398	0
IDEXX LABS INC	COM	45168D104	18,390	36,801	SH		DFND	4,9	0	36,801	0
IES HLDGS INC	COM	44951W106	321	6,976	SH		DFND	10	0	6,976	0
IGM BIOSCIENCES INC	COM	449585108	44,299	501,745	SH		DFND	10	0	485,321	16,424
IHS MARKIT LTD	SHS	G47567105	209,551	2,332,785	SH		DFND	4,9,10	0	1,809,687	523,098
ILLINOIS TOOL WKS INC	COM	452308109	16,381	80,350	SH		DFND	4,9	0	80,350	0
ILLUMINA INC	COM	452327109	1,013,244	2,738,465	SH		DFND	4,9,10	0	2,623,713	114,752
IMPERIAL OIL LTD	COM NEW	453038408	1,377	72,587	SH		DFND	4,9	0	72,587	0
IMPINJ INC	COM	453204109	29,575	706,765	SH		DFND	4	0	706,765	0
INCYTE CORP	COM	45337C102	4,424	50,870	SH		DFND	4,9,10	0	49,818	1,052
INDEPENDENCE RLTY TR INC	COM	45378A106	348	25,933	SH		DFND	10	0	25,933	0
INDEPENDENT BANK CORP MASS	COM	453836108	24,314	332,882	SH		DFND	2,10	0	332,882	0
INDEPENDENT BK GROUP INC	COM	45384B106	221	3,530	SH		DFND	10	0	3,530	0
INGERSOLL RAND INC	COM	45687V106	426,545	9,362,272	SH		DFND	4,9,10	0	9,052,999	309,273
INGEVITY CORP	COM	45688C107	1,260	16,642	SH		DFND	10	0	16,642	0
INHIBRX INC	COM	45720L107	1,754	53,213	SH		DFND	10	0	53,213	0
INNOSPEC INC	COM	45768S105	73,133	806,049	SH		DFND	2	0	806,049	0
INNOVIVA INC	COM	45781M101	1,773	143,072	SH		DFND	10	0	143,072	0
INOGEN INC	COM	45780L104	1,394	31,209	SH		DFND	10	0	31,209	0
INSIGHT ENTERPRISES INC	COM	45765U103	41,562	546,223	SH		DFND	2,10	0	546,223	0
INSMED INC	COM PAR $.01	457669307	193,831	5,822,413	SH		DFND	10	0	5,645,161	177,252
INSPERITY INC	COM	45778Q107	1,035	12,709	SH		DFND	10	0	12,709	0
INSTALLED BLDG PRODS INC	COM	45780R101	748	7,335	SH		DFND	10	0	7,335	0
INSU ACQUISITION CORP III	UNIT 12/31/2026	457817302	212	20,000	SH		DFND	4	0	20,000	0
INSULET CORP	COM	45784P101	183,814	719,062	SH		DFND	4,9,10	0	325,280	393,782
INTEGRA LIFESCIENCES HLDGS C	COM NEW	457985208	300,071	4,622,163	SH		DFND	10	0	4,459,092	163,071
INTEGRA RES CORP	COM NEW	45826T301	640	163,118	SH		DFND	11	0	163,118	0
INTEL CORP	COM	458140100	258,605	5,190,645	SH		DFND	2,4,9,10	0	4,483,041	707,604
INTELLIGENT SYS CORP NEW	COM	45816D100	19,095	481,061	SH		DFND	10	0	466,235	14,826
INTERACTIVE BROKERS GROUP IN	COM CL A	45841N107	3,097	50,830	SH		DFND	9	0	49,329	1,501
INTERCONTINENTAL EXCHANGE IN	COM	45866F104	101,894	883,924	SH		DFND	4,9,10	0	867,036	16,888
INTERNATIONAL BUSINESS MACHS	COM	459200101	366,703	2,913,144	SH		DFND	4,9,10	0	1,281,243	1,631,901
INTERNATIONAL FLAVORS&FRAGRA	COM	459506101	26,027	239,135	SH		DFND	4,9	0	138,872	100,263
INTERNATIONAL FLAVORS&FRAGRA	COM	459506101	23	208	SH		DFND	4	0	208	0
INTERNATIONAL PAPER CO	COM	460146103	14,487	291,500	SH		DFND	4,9,11	0	290,450	1,050
INTERPUBLIC GROUP COS INC	COM	460690100	49,494	2,104,357	SH		DFND	4,9,10	0	732,182	1,372,175
INTRA CELLULAR THERAPIES INC	COM	46116X101	1,489	46,783	SH		DFND	10	0	46,783	0
INTRUSION INC	COM NEW	46121E205	518	29,405	SH		DFND	10	0	29,405	0
INTUIT	COM	461202103	626,071	1,648,115	SH		DFND	4,9,10	0	1,237,755	410,360
INTUITIVE SURGICAL INC	COM NEW	46120E602	336,678	411,548	SH		DFND	4,9,10	0	383,413	28,135
INVESCO LTD	SHS	G491BT108	1,463	83,949	SH		DFND	4,9	0	83,949	0
INVESCO QQQ TR	UNIT SER 1	46090E103	42,711	136,136	SH		DFND	10	0	136,136	0
INVITATION HOMES INC	COM	46187W107	59,035	1,988,046	SH		DFND	4,9,10,12	0	1,925,378	62,668
IONIS PHARMACEUTICALS INC	COM	462222100	2,862	50,626	SH		DFND	4,9,10	0	44,412	6,214
IOVANCE BIOTHERAPEUTICS INC	COM	462260100	834	18,004	SH		DFND	9,10	0	0	18,004
IPG PHOTONICS CORP	COM	44980X109	58,822	263,122	SH		DFND	4,9,10	0	263,122	0
IQVIA HLDGS INC	COM	46266C105	375,311	2,094,736	SH		DFND	4,9,10	0	1,873,692	221,044
IRADIMED CORP	COM	46266A109	301	13,196	SH		DFND	10	0	13,196	0
IRON MTN INC NEW	COM	46284V101	3,765	127,735	SH		DFND	4,9	0	95,115	32,620
ISHARES TR	20 YR TR BD ETF	464287432	1,389	8,806	SH		DFND	10	0	8,806	0
ISHARES TR	BARCLAYS 7 10 YR	464287440	442	3,688	SH		DFND	10	0	3,688	0
ISHARES TR	CORE S&P500 ETF	464287200	15,013	39,993	SH		DFND	10	0	39,993	0
ISHARES TR	CORE US AGGBD ET	464287226	113,056	956,559	SH		DFND	10	0	956,559	0
ISHARES TR	IBOXX HI YD ETF	464288513	349	3,996	SH		DFND	10	0	3,996	0
ISHARES TR	IBOXX INV CP ETF	464287242	743	5,381	SH		DFND	10	0	5,381	0
ISHARES TR	RUS 1000 GRW ETF	464287614	1,313	5,447	SH		DFND	10	0	59	5,388
ITAU UNIBANCO HLDG S A	SPON ADR REP PFD	465562106	21,696	3,559,885	SH		DFND	4,10	0	3,559,885	0
ITEOS THERAPEUTICS INC	COM	46565G104	64,662	1,988,130	SH		DFND	10	0	1,952,654	35,476
ITRON INC	COM	465741106	77,765	810,897	SH		DFND	10	0	774,693	36,204
ITT INC	COM	45073V108	159,439	2,070,102	SH		DFND	4,9,10	0	2,005,581	64,521
J P MORGAN EXCHANGE-TRADED F	BETABULDR DEVE	46641Q688	14,466	534,578	SH		DFND	10	0	534,578	0
J2 GLOBAL INC	COM	48123V102	192,142	1,966,850	SH		DFND	10	0	1,888,926	77,924
JABIL INC	COM	466313103	53,385	1,255,528	SH		DFND	4,9	0	1,255,203	325
JACOBS ENGR GROUP INC	COM	469814107	15,107	138,641	SH		DFND	4,9	0	131,126	7,515
JANUS DETROIT STR TR	HENDRSN SHRT ETF	47103U886	5,147	101,991	SH		DFND	10	0	992	100,999
JANUS DETROIT STR TR	HENDRSON AAA CL	47103U845	20,116	400,000	SH		DFND	10	0	0	400,000
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	143,858	871,600	SH		DFND	4,9,10	0	846,315	25,285
JD.COM INC	SPON ADR CL A	47215P106	75,659	860,930	SH		DFND	4,9,10,12	0	762,261	98,669
JEFFERIES FINL GROUP INC	COM	47233W109	7,936	322,582	SH		DFND	9	0	176,661	145,921
JETBLUE AWYS CORP	COM	477143101	3,563	244,980	SH		DFND	4	0	244,980	0
JFROG LTD	ORD SHS	M6191J100	4,921	78,322	SH		DFND	10	0	52,638	25,684
JIYA ACQUISITION CORP	COM CL A	47760M102	2,059	200,092	SH		DFND	10	0	200,092	0
JOHN BEAN TECHNOLOGIES CORP	COM	477839104	27,961	245,553	SH		DFND	4,10	0	236,908	8,645
JOHNSON & JOHNSON	COM	478160104	403,021	2,561,053	SH		DFND	2,4,9,10	0	2,272,766	288,287
JOHNSON CTLS INTL PLC	SHS	G51502105	152,051	3,263,607	SH		DFND	4,9	0	419,801	2,843,806
JOHNSON OUTDOORS INC	CL A	479167108	246	2,185	SH		DFND	10	0	2,185	0
JOINT CORP	COM	47973J102	520	19,811	SH		DFND	10	0	19,811	0
JPMORGAN CHASE & CO	COM	46625H100	559,726	4,405,673	SH		DFND	4,9,10	0	4,164,309	241,364
JUNIPER NETWORKS INC	COM	48203R104	8,112	360,382	SH		DFND	4,9	0	283,233	77,149
KADANT INC	COM	48282T104	631	4,475	SH		DFND	4,10	0	4,475	0
KALVISTA PHARMACEUTICALS INC	COM	483497103	3,049	160,511	SH		DFND	10	0	160,511	0
KANSAS CITY SOUTHERN	COM NEW	485170302	84,069	411,835	SH		DFND	4,9,10	0	355,298	56,537
KAR AUCTION SVCS INC	COM	48238T109	33,209	1,784,453	SH		DFND	2,4	0	1,784,453	0
KELLOGG CO	COM	487836108	207,255	3,330,475	SH		DFND	4,9,10	0	1,313,201	2,017,274
KEURIG DR PEPPER INC	COM	49271V100	5,399	168,712	SH		DFND	4,9	0	123,848	44,864
KEYCORP	COM	493267108	4,814	293,389	SH		DFND	4,9	0	293,389	0
KEYSIGHT TECHNOLOGIES INC	COM	49338L103	30,757	232,840	SH		DFND	4,9	0	123,898	108,942
KIMBERLY-CLARK CORP	COM	494368103	137,700	1,021,307	SH		DFND	4,9	0	403,627	617,680
KIMCO RLTY CORP	COM	49446R109	3,075	204,882	SH		DFND	4,9	0	204,364	518
KINDER MORGAN INC DEL	COM	49456B101	15,212	1,112,921	SH		DFND	4,9	0	1,005,689	107,232
KINIKSA PHARMACEUTICALS LTD	COM CL A	G5269C101	20,019	1,132,948	SH		DFND	10	0	1,085,600	47,348
KINNATE BIOPHARMA INC	COM	49705R105	30,367	805,769	SH		DFND	10	0	805,769	0
KINROSS GOLD CORP	COM	496902404	9,732	1,326,877	SH		DFND	4,9,11	0	1,326,877	0
KINS TECHNOLOGY GROUP INC	UNIT 10/14/2025	49714K208	258	25,000	SH		DFND	4	0	25,000	0
KINSALE CAP GROUP INC	COM	49714P108	208	1,039	SH		DFND	10	0	1,039	0
KIRKLAND LAKE GOLD LTD	COM	49741E100	9,610	233,045	SH		DFND	4,9,11	0	233,045	0
KKR & CO INC	COM	48251W104	3,937	97,190	SH		DFND	4,9	0	97,190	0
KLA CORP	COM NEW	482480100	921,013	3,557,258	SH		DFND	4,9,10	0	3,275,737	281,521
KNIGHT-SWIFT TRANSN HLDGS IN	CL A	499049104	5,017	119,955	SH		DFND	4,9	0	105,081	14,874
KODIAK SCIENCES INC	COM	50015M109	49,532	337,174	SH		DFND	10	0	328,033	9,141
KORN FERRY	COM NEW	500643200	48,837	1,122,698	SH		DFND	2	0	1,122,698	0
KORNIT DIGITAL LTD	SHS	M6372Q113	51,018	572,395	SH		DFND	10	0	555,084	17,311
KRAFT HEINZ CO	COM	500754106	258,735	7,465,330	SH		DFND	4,9	0	3,912,077	3,553,253
KROGER CO	COM	501044101	105,190	3,312,038	SH		DFND	4,9	0	1,349,061	1,962,977
KURA ONCOLOGY INC	COM	50127T109	2,810	86,038	SH		DFND	4,10	0	86,038	0
L3HARRIS TECHNOLOGIES INC	COM	502431109	1,569,118	8,301,442	SH		DFND	4,9,10	0	8,031,141	270,301
LABORATORY CORP AMER HLDGS	COM NEW	50540R409	87,701	430,860	SH		DFND	2,4,9	0	422,150	8,710
LAIRD SUPERFOOD INC	COM STK	50736T102	5,912	124,942	SH		DFND	10	0	95,605	29,337
LAM RESEARCH CORP	COM	512807108	2,105,415	4,458,150	SH		DFND	4,9,10	0	4,121,758	336,392
LAMAR ADVERTISING CO NEW	CL A	512816109	596,569	7,168,578	SH		DFND	2,4,9,10	0	6,976,619	191,959
LAMB WESTON HLDGS INC	COM	513272104	5,363	68,111	SH		DFND	2,4,9	0	68,111	0
LANDSTAR SYS INC	COM	515098101	4,444	33,004	SH		DFND	9	0	28,114	4,890
LARIMAR THERAPEUTICS INC	COM	517125100	2,966	138,745	SH		DFND	10	0	138,745	0
LAS VEGAS SANDS CORP	COM	517834107	38,292	642,465	SH		DFND	4,9,10	0	580,092	62,373
LAUDER ESTEE COS INC	CL A	518439104	298,543	1,121,682	SH		DFND	4,9,10	0	1,025,878	95,804
LCI INDS	COM	50189K103	803	6,192	SH		DFND	10	0	6,192	0
LEAR CORP	COM NEW	521865204	2,056	12,930	SH		DFND	4,9	0	12,930	0
LEGGETT & PLATT INC	COM	524660107	65,388	1,476,031	SH		DFND	2,9,10	0	1,455,069	20,962
LEIDOS HOLDINGS INC	COM	525327102	113,204	1,076,904	SH		DFND	4,9	0	506,897	570,007
LEMAITRE VASCULAR INC	COM	525558201	1,162	28,701	SH		DFND	10	0	28,701	0
LENDINGTREE INC NEW	COM	52603B107	101,151	369,448	SH		DFND	10	0	356,155	13,293
LENNAR CORP	CL A	526057104	11,611	152,331	SH		DFND	4,9,10	0	147,325	5,006
LENNOX INTL INC	COM	526107107	2,193	8,000	SH		DFND	4,9	0	8,000	0
LESLIES INC	COM	527064109	45,897	1,653,935	SH		DFND	10	0	1,532,723	121,212
LEVI STRAUSS & CO NEW	CL A COM STK	52736R102	50,352	2,507,588	SH		DFND	2	0	2,507,588	0
LGI HOMES INC	COM	50187T106	6,308	59,597	SH		DFND	10	0	59,597	0
LHC GROUP INC	COM	50187A107	3,146	14,749	SH		DFND	10	0	14,749	0
LIBERTY BROADBAND CORP	COM SER A	530307107	6,631	42,083	SH		DFND	4,9	0	28,552	13,531
LIBERTY BROADBAND CORP	COM SER C	530307305	54,965	347,065	SH		DFND	4,9,10	0	279,050	68,015
LIBERTY GLOBAL PLC	SHS CL A	G5480U104	5,298	218,719	SH		DFND	4,9	0	40,683	178,036
LIBERTY GLOBAL PLC	SHS CL C	G5480U120	11,868	501,823	SH		DFND	4,9	0	104,600	397,223
LIBERTY MEDIA CORP DEL	COM A SIRIUSXM	531229409	579	13,410	SH		DFND	4,9	0	13,410	0
LIBERTY MEDIA CORP DEL	COM C SIRIUSXM	531229607	1,988	45,679	SH		DFND	4,9	0	45,679	0
LIBERTY MEDIA CORP DEL	COM SER C FRMLA	531229854	597,320	14,021,602	SH		DFND	4,9,10	0	13,343,909	677,693
LIGAND PHARMACEUTICALS INC	COM NEW	53220K504	160,350	1,612,369	SH		DFND	10	0	1,551,608	60,761
LILLY ELI & CO	COM	532457108	1,034,108	6,124,921	SH		DFND	4,9,10	0	5,933,344	191,577
LINCOLN ELEC HLDGS INC	COM	533900106	137,523	1,182,990	SH		DFND	2,9	0	1,182,990	0
LINCOLN NATL CORP IND	COM	534187109	2,258	44,887	SH		DFND	4,9	0	44,887	0
LINDE PLC	SHS	G5494J103	74,402	282,366	SH		DFND	4,9	0	229,705	52,661
LITHIA MTRS INC	CL A	536797103	1,003	3,426	SH		DFND	4,10	0	3,426	0
LITTELFUSE INC	COM	537008104	927	3,640	SH		DFND	9	0	3,640	0
LIVE NATION ENTERTAINMENT IN	COM	538034109	3,385	46,072	SH		DFND	4,9	0	46,072	0
LIVENT CORP	COM	53814L108	2,204	116,965	SH		DFND	10	0	116,965	0
LIVEPERSON INC	COM	538146101	170,378	2,737,881	SH		DFND	10	0	2,626,202	111,679
LIVERAMP HLDGS INC	COM	53815P108	167,537	2,289,065	SH		DFND	10	0	2,201,037	88,028
LKQ CORP	COM	501889208	6,278	178,142	SH		DFND	4,9	0	59,617	118,525
LOCKHEED MARTIN CORP	COM	539830109	150,597	424,247	SH		DFND	4,9,10	0	388,699	35,548
LOEWS CORP	COM	540424108	3,042	67,556	SH		DFND	4,9	0	67,556	0
LOGITECH INTL S A	SHS	H50430232	7,161	73,681	SH		DFND	4,9	0	30,887	42,794
LOVESAC COMPANY	COM	54738L109	37,875	878,978	SH		DFND	10	0	840,845	38,133
LOWES COS INC	COM	548661107	190,015	1,183,827	SH		DFND	4,9	0	770,257	413,570
LPL FINL HLDGS INC	COM	50212V100	846,087	8,118,279	SH		DFND	9,10	0	7,826,566	291,713
LTC PPTYS INC	COM	502175102	323	8,301	SH		DFND	10	0	8,301	0
LULULEMON ATHLETICA INC	COM	550021109	197,036	566,152	SH		DFND	4,9,10	0	265,443	300,709
LUMEN TECHNOLOGIES INC	COM	156700106	73,727	7,561,794	SH		DFND	4,9	0	2,122,229	5,439,565
LUMENTUM HLDGS INC	COM	55024U109	91,135	960,985	SH		DFND	4	0	960,985	0
LYFT INC	CL A COM	55087P104	988	20,100	SH		DFND	4	0	20,100	0
LYONDELLBASELL INDUSTRIES N	SHS - A -	N53745100	13,520	147,491	SH		DFND	4,9	0	140,802	6,689
M & T BK CORP	COM	55261F104	74,628	586,234	SH		DFND	2,4,9	0	574,741	11,493
M D C HLDGS INC	COM	552676108	776	15,969	SH		DFND	10	0	15,969	0
M/I HOMES INC	COM	55305B101	313	7,076	SH		DFND	10	0	7,076	0
MACQUARIE INFRASTRUCTURE COR	COM	55608B105	245	6,518	SH		DFND	9	0	1,666	4,852
MADDEN STEVEN LTD	COM	556269108	67,911	1,922,743	SH		DFND	2	0	1,922,743	0
MADISON SQUARE GRDN SPRT COR	CL A	55825T103	43,577	236,705	SH		DFND	2,9	0	236,622	83
MAGELLAN MIDSTREAM PRTNRS LP	COM UNIT RP LP	559080106	325,210	7,662,826	SH		DFND	10	0	7,662,826	0
MAGNA INTL INC	COM	559222401	5,862	82,693	SH		DFND	4,9	0	82,693	0
MALIBU BOATS INC	COM CL A	56117J100	318	5,099	SH		DFND	10	0	5,099	0
MANCHESTER UTD PLC NEW	ORD CL A	G5784H106	18,469	1,103,276	SH		DFND	10	0	1,056,860	46,416
MANPOWERGROUP INC	COM	56418H100	5,673	62,909	SH		DFND	9	0	32,063	30,846
MANULIFE FINL CORP	COM	56501R106	2	107	SH		DFND	4	0	107	0
MANULIFE FINL CORP	COM	56501R106	217,853	12,249,584	SH		DFND	4,9	0	7,126,040	5,123,544
MARATHON OIL CORP	COM	565849106	296	44,340	SH		DFND	9	0	24,216	20,124
MARATHON PETE CORP	COM	56585A102	31,001	749,557	SH		DFND	2,4,9,10	0	683,067	66,490
MARAVAI LIFESCIENCES HLDGS I	COM CL A	56600D107	23,009	820,275	SH		DFND	10	0	820,275	0
MARCUS & MILLICHAP INC	COM	566324109	45,866	1,231,955	SH		DFND	2	0	1,231,955	0
MARKEL CORP	COM	570535104	3,302	3,196	SH		DFND	4,9	0	3,196	0
MARKETAXESS HLDGS INC	COM	57060D108	42,681	74,811	SH		DFND	4,9,10	0	31,317	43,494
MARQUEE RAINE ACQUISITION CO	UNIT 12/01/2025	G58442115	217	20,000	SH		DFND	4	0	20,000	0
MARRIOTT INTL INC NEW	CL A	571903202	8,700	65,946	SH		DFND	4,9	0	65,946	0
MARSH & MCLENNAN COS INC	COM	571748102	246,480	2,106,689	SH		DFND	4,9,10	0	2,064,724	41,965
MARTEN TRANS LTD	COM	573075108	472	27,397	SH		DFND	10	0	27,397	0
MARTIN MARIETTA MATLS INC	COM	573284106	51,837	182,539	SH		DFND	2,4,9	0	176,556	5,983
MARVELL TECHNOLOGY GROUP LTD	ORD	G5876H105	173,819	3,656,277	SH		DFND	4,9,10	0	3,656,277	0
MASCO CORP	COM	574599106	5,332	97,100	SH		DFND	4,9	0	96,714	386
MASIMO CORP	COM	574795100	6,755	25,170	SH		DFND	4,9	0	13,281	11,889
MASTERCARD INCORPORATED	CL A	57636Q104	4,003,395	11,216,598	SH		DFND	4,9,10	0	10,276,440	940,158
MATCH GROUP INC NEW	COM	57667L107	485,753	3,212,798	SH		DFND	4,9,10	0	2,832,277	380,521
MAXIM INTEGRATED PRODS INC	COM	57772K101	107,367	1,211,217	SH		DFND	2,4,9	0	1,093,401	117,816
MAXIMUS INC	COM	577933104	68,569	936,860	SH		DFND	10	0	902,882	33,978
MCCORMICK & CO INC	COM NON VTG	579780206	80,581	842,909	SH		DFND	4,9,10	0	765,991	76,918
MCDONALDS CORP	COM	580135101	1,186,551	5,529,653	SH		DFND	4,9,10	0	5,140,560	389,093
MCGRATH RENTCORP	COM	580589109	536	7,990	SH		DFND	10	0	7,990	0
MCKESSON CORP	COM	58155Q103	7,288	41,894	SH		DFND	4,9	0	41,441	453
MEDALLIA INC	COM	584021109	34,097	1,026,411	SH		DFND	10	0	943,569	82,842
MEDICAL PPTYS TRUST INC	COM	58463J304	13,390	614,502	SH		DFND	4,9	0	281,900	332,602
MEDIFAST INC	COM	58470H101	1,279	6,515	SH		DFND	10	0	6,515	0
MEDPACE HLDGS INC	COM	58506Q109	4,167	29,938	SH		DFND	10	0	29,938	0
MEDTRONIC PLC	SHS	G5960L103	901,941	7,699,813	SH		DFND	2,4,9,10	0	6,622,425	1,077,388
MELCO RESORTS AND ENTMNT LTD	ADR	585464100	1,616	87,125	SH		DFND	4,9	0	87,125	0
MERCADOLIBRE INC	COM	58733R102	235,511	140,599	SH		DFND	4,9,10	0	107,656	32,943
MERCK & CO. INC	COM	58933Y105	1,955,653	23,908,304	SH		DFND	2,4,9,10	0	22,472,319	1,435,985
MERCURY GENL CORP NEW	COM	589400100	563	10,786	SH		DFND	9	0	9,018	1,768
MEREO BIOPHARMA GROUP PLC	ADS	589492107	3,998	1,124,678	SH		DFND	10	0	1,124,678	0
MERSANA THERAPEUTICS INC	COM	59045L106	24,455	919,101	SH		DFND	10	0	883,088	36,013
METLIFE INC	COM	59156R108	8,590	182,970	SH		DFND	4,9	0	182,970	0
METTLER TOLEDO INTERNATIONAL	COM	592688105	22,521	19,759	SH		DFND	4,9	0	11,438	8,321
MGIC INVT CORP WIS	COM	552848103	64,326	5,125,595	SH		DFND	10	0	5,094,140	31,455
MGM GROWTH PPTYS LLC	CL A COM	55303A105	73,870	2,360,447	SH		DFND	4,10,12	0	1,889,532	470,915
MGM RESORTS INTERNATIONAL	COM	552953101	5,345	169,667	SH		DFND	4,9,10	0	169,667	0
MGP INGREDIENTS INC NEW	COM	55303J106	323	6,874	SH		DFND	10	0	6,874	0
MICROCHIP TECHNOLOGY INC.	COM	595017104	1,245,560	9,019,043	SH		DFND	4,9,10	0	8,511,076	507,967
MICRON TECHNOLOGY INC	COM	595112103	121,639	1,617,892	SH		DFND	4,9,10	0	1,503,646	114,246
MICROSOFT CORP	COM	594918104	10,191,930	45,826,930	SH		DFND	2,4,9,10	0	40,757,892	5,069,038
MID-AMER APT CMNTYS INC	COM	59522J103	33,532	264,680	SH		DFND	4,9	0	112,059	152,621
MIDDLEBY CORP	COM	596278101	170,824	1,325,037	SH		DFND	10	0	1,286,567	38,470
MIRATI THERAPEUTICS INC	COM	60468T105	253,151	1,152,569	SH		DFND	10	0	1,117,321	35,248
MISSION PRODUCE INC	COM	60510V108	578	38,374	SH		DFND	10	0	38,374	0
MOBILE TELESYSTEMS PJSC	SPONSORED ADR	607409109	600	67,049	SH		DFND	9	0	67,049	0
MODERNA INC	COM	60770K107	15,595	149,292	SH		DFND	4,9,10	0	91,702	57,590
MOHAWK INDS INC	COM	608190104	2,250	15,968	SH		DFND	4,9	0	15,968	0
MOLINA HEALTHCARE INC	COM	60855R100	1,359	6,390	SH		DFND	4,9	0	5,933	457
MOLSON COORS BEVERAGE CO	CL B	60871R209	3,559	78,750	SH		DFND	4,9	0	78,099	651
MOMO INC	ADR	60879B107	667	47,750	SH		DFND	9	0	47,750	0
MONARCH CASINO & RESORT INC	COM	609027107	53,792	878,668	SH		DFND	10	0	865,065	13,603
MONDELEZ INTL INC	CL A	609207105	41,348	707,312	SH		DFND	4,9,10	0	678,034	29,278
MONGODB INC	CL A	60937P106	58,499	162,928	SH		DFND	4,9,10	0	53,951	108,977
MONOLITHIC PWR SYS INC	COM	609839105	2,688	7,340	SH		DFND	4,9	0	7,340	0
MONSTER BEVERAGE CORP NEW	COM	61174X109	430,937	4,659,822	SH		DFND	4,9,10	0	4,211,665	448,157
MONTROSE ENVIRONMENTAL GROUP	COM	615111101	21,778	703,411	SH		DFND	10	0	674,680	28,731
MOODYS CORP	COM	615369105	80,248	276,619	SH		DFND	4,9	0	262,023	14,596
MORGAN STANLEY	COM NEW	617446448	854,988	12,476,174	SH		DFND	4,9,10	0	12,397,830	78,344
MORNINGSTAR INC	COM	617700109	6,923	29,897	SH		DFND	9	0	19,198	10,699
MOSAIC CO NEW	COM	61945C103	10,675	463,994	SH		DFND	4,9,11	0	463,994	0
MOTOROLA SOLUTIONS INC	COM NEW	620076307	264,306	1,554,204	SH		DFND	2,4,9,10	0	1,525,443	28,761
MSC INDL DIRECT INC	CL A	553530106	89,977	1,066,203	SH		DFND	2	0	1,066,203	0
MSCI INC	COM	55354G100	201,199	450,590	SH		DFND	4,9,10	0	439,232	11,358
MYOVANT SCIENCES LTD	COM	G637AM102	140,815	5,098,315	SH		DFND	10	0	4,941,519	156,796
NAPCO SEC TECHNOLOGIES INC	COM	630402105	21,247	810,325	SH		DFND	10	0	777,234	33,091
NASDAQ INC	COM	631103108	4,187	31,551	SH		DFND	4,9	0	31,551	0
NATERA INC	COM	632307104	77,217	775,894	SH		DFND	10	0	743,190	32,704
NATIONAL BEVERAGE CORP	COM	635017106	2,191	25,801	SH		DFND	10	0	25,801	0
NATIONAL GRID PLC	SPONSORED ADR NE	636274409	295	5,000	SH		DFND	4	0	5,000	0
NATIONAL HEALTH INVS INC	COM	63633D104	1,984	28,660	SH		DFND	4,10	0	28,660	0
NATIONAL INSTRS CORP	COM	636518102	413,438	9,409,156	SH		DFND	9,10	0	9,144,260	264,896
NATIONAL RESH CORP	COM NEW	637372202	1,526	35,704	SH		DFND	10	0	35,704	0
NATIONAL VISION HLDGS INC	COM	63845R107	122,031	2,694,439	SH		DFND	10	0	2,605,202	89,237
NATUS MED INC DEL	COM	639050103	22,838	1,139,631	SH		DFND	2	0	1,139,631	0
NCR CORP NEW	COM	62886E108	99,161	2,639,356	SH		DFND	9,10	0	2,553,070	86,286
NEOGENOMICS INC	COM NEW	64049M209	146,285	2,717,023	SH		DFND	4,10	0	2,626,354	90,669
NETAPP INC	COM	64110D104	3,871	58,431	SH		DFND	4,9	0	58,431	0
NETEASE INC	SPONSORED ADS	64110W102	70,827	739,941	SH		DFND	4,9,12	0	603,357	136,584
NETFLIX INC	COM	64110L106	1,803,455	3,334,980	SH		DFND	4,9,10	0	2,914,029	420,951
NEUROCRINE BIOSCIENCES INC	COM	64125C109	878,094	9,161,141	SH		DFND	4,9,10	0	8,758,736	402,405
NEUROCRINE BIOSCIENCES INC	NOTE 2.250% 5/1	64125CAD1	15,414	11,144,000	SH		DFND	4,10	0	11,144,000	0
NEW ORIENTAL ED & TECHNOLOGY	SPON ADR	647581107	91,930	494,457	SH		DFND	4,9,10,12	0	494,457	0
NEW RESIDENTIAL INVT CORP	COM NEW	64828T201	4,402	442,886	SH		DFND	9	0	218,778	224,108
NEW SR INVT GROUP INC	COM	648691103	86	16,527	SH		DFND	10	0	16,527	0
NEW YORK CMNTY BANCORP INC	COM	649445103	905	85,751	SH		DFND	9	0	15,276	70,475
NEW YORK TIMES CO	CL A	650111107	10,780	208,230	SH		DFND	9	0	132,933	75,297
NEWELL BRANDS INC	COM	651229106	70,700	3,330,243	SH		DFND	4,9	0	935,389	2,394,854
NEWMARK GROUP INC	CL A	65158N102	345	47,281	SH		DFND	10	0	47,281	0
NEWMARKET CORP	COM	651587107	107,482	269,858	SH		DFND	2	0	269,858	0
NEWMONT CORP	COM	651639106	215,522	3,598,563	SH		DFND	4,9,10	0	1,948,237	1,650,326
NEWMONT CORP	COM	651639106	3,427	57,207	SH		DFND	4	0	57,207	0
NEWS CORP NEW	CL A	65249B109	8,268	460,090	SH		DFND	4,9	0	206,528	253,562
NEXGEN ENERGY LTD	COM	65340P106	3,109	1,128,613	SH		DFND	11	0	1,128,613	0
NEXPOINT RESIDENTIAL TR INC	COM	65341D102	309	7,313	SH		DFND	10	0	7,313	0
NEXTERA ENERGY INC	COM	65339F101	127,148	1,648,515	SH		DFND	4,9,11	0	919,203	729,312
NICE LTD	SPONSORED ADR	653656108	1,191,403	4,201,886	SH		DFND	10	0	3,987,349	214,537
NIELSEN HLDGS PLC	SHS EUR	G6518L108	824	39,466	SH		DFND	4,9	0	37,904	1,562
NIKE INC	CL B	654106103	1,640,312	11,594,788	SH		DFND	4,9,10	0	10,031,323	1,563,465
NIO INC	SPON ADS	62914V106	3,567	73,176	SH		DFND	9,10	0	73,176	0
NISOURCE INC	COM	65473P105	3,787	165,117	SH		DFND	4,9	0	165,117	0
NOMAD FOODS LTD	USD ORD SHS	G6564A105	53,704	2,112,665	SH		DFND	2	0	2,112,665	0
NORDSON CORP	COM	655663102	147,327	733,153	SH		DFND	4,9,10	0	706,052	27,101
NORFOLK SOUTHN CORP	COM	655844108	18,475	77,759	SH		DFND	4,9,10	0	75,366	2,393
NORTHERN TR CORP	COM	665859104	4,879	52,393	SH		DFND	4,9	0	52,393	0
NORTHROP GRUMMAN CORP	COM	666807102	21,755	71,393	SH		DFND	4,9,10	0	65,892	5,501
NORTHWESTERN CORP	COM NEW	668074305	30,319	519,969	SH		DFND	2	0	519,969	0
NORTONLIFELOCK INC	COM	668771108	158,364	7,621,676	SH		DFND	4,9	0	4,615,888	3,005,788
NORWEGIAN CRUISE LINE HLDG L	SHS	G66721104	1,561	61,403	SH		DFND	9,10	0	61,403	0
NOVANTA INC	COM	67000B104	32,893	278,236	SH		DFND	10	0	259,589	18,647
NOVARTIS AG	SPONSORED ADR	66987V109	440,950	4,669,601	SH		DFND	4,10	0	4,536,986	132,615
NOVOCURE LTD	ORD SHS	G6674U108	969	5,614	SH		DFND	9,10	0	5,614	0
NOVO-NORDISK A S	ADR	670100205	13,633	195,169	SH		DFND	10	0	195,169	0
NOVUS CAP CORP	COM	67012U108	20,306	1,297,516	SH		DFND	10	0	1,242,069	55,447
NOW INC	COM	67011P100	90	12,500	SH		DFND	4	0	12,500	0
NRG ENERGY INC	COM NEW	629377508	304,093	8,098,350	SH		DFND	4,9,10	0	7,717,333	381,017
NUANCE COMMUNICATIONS INC	COM	67020Y100	1,667	37,814	SH		DFND	9	0	36,910	904
NUCOR CORP	COM	670346105	7,461	140,280	SH		DFND	4,9,11	0	140,280	0
NUTRIEN LTD	COM	67077M108	122,070	2,537,265	SH		DFND	2,4,9,11	0	2,151,875	385,390
NUTRIEN LTD	COM	67077M108	34,481	715,968	SH		DFND	2	0	697,680	18,288
NV5 GLOBAL INC	COM	62945V109	346	4,390	SH		DFND	10	0	4,390	0
NVIDIA CORPORATION	COM	67066G104	2,223,429	4,257,857	SH		DFND	4,9,10	0	3,853,717	404,140
NVR INC	COM	62944T105	30,561	7,483	SH		DFND	4,9,10,12	0	7,254	229
NXP SEMICONDUCTORS N V	COM	N6596X109	187,107	1,176,680	SH		DFND	4,9,10	0	1,150,597	26,083
OAK STR HEALTH INC	COM	67181A107	24,615	402,469	SH		DFND	10	0	374,744	27,725
OCCIDENTAL PETE CORP	COM	674599105	8,131	469,751	SH		DFND	4,9	0	357,591	112,160
ODONATE THERAPEUTICS INC	COM	676079106	52,286	2,723,248	SH		DFND	10	0	2,643,627	79,621
OGE ENERGY CORP	COM	670837103	653	20,497	SH		DFND	4,9	0	20,497	0
OKTA INC	CL A	679295105	62,528	245,917	SH		DFND	4,9	0	66,341	179,576
OLD DOMINION FREIGHT LINE IN	COM	679580100	18,535	94,958	SH		DFND	4,9	0	90,349	4,609
OLD REP INTL CORP	COM	680223104	517	26,213	SH		DFND	9	0	5,825	20,388
OLEMA PHARMACEUTICALS INC	COM	68062P106	160,929	3,638,838	SH		DFND	10	0	3,586,677	52,161
OLLIES BARGAIN OUTLET HLDGS	COM	681116109	812	9,936	SH		DFND	9,10	0	9,936	0
OMEGA HEALTHCARE INVS INC	COM	681936100	2,846	78,347	SH		DFND	4,9,10	0	78,347	0
OMNICOM GROUP INC	COM	681919106	33,938	544,160	SH		DFND	4,9	0	128,726	415,434
ON SEMICONDUCTOR CORP	COM	682189105	655,723	20,034,310	SH		DFND	4,9,10	0	19,397,287	637,023
ONCORUS INC	COM	68236R103	2,335	72,572	SH		DFND	10	0	72,572	0
ONEMAIN HLDGS INC	COM	68268W103	279	5,796	SH		DFND	4,9	0	2,306	3,490
ONEOK INC NEW	COM	682680103	4,649	121,138	SH		DFND	4,9	0	121,138	0
OPEN TEXT CORP	COM	683715106	2,519	55,462	SH		DFND	4,9	0	55,462	0
ORACLE CORP	COM	68389X105	337,866	5,223,164	SH		DFND	2,4,9,10	0	4,155,811	1,067,353
OREILLY AUTOMOTIVE INC	COM	67103H107	32,003	70,711	SH		DFND	2,4,9,10	0	70,711	0
ORMAT TECHNOLOGIES INC	COM	686688102	277	3,063	SH		DFND	10	0	3,063	0
OSI SYSTEMS INC	COM	671044105	171,048	1,834,887	SH		DFND	10	0	1,767,197	67,690
OSISKO GOLD ROYALTIES LTD	COM	68827L101	7,002	552,323	SH		DFND	11	0	552,323	0
OTIS WORLDWIDE CORP	COM	68902V107	49,560	733,689	SH		DFND	4,9,10	0	308,465	425,224
OUTFRONT MEDIA INC	COM	69007J106	2,163	110,580	SH		DFND	9	0	63,549	47,031
OUTSET MED INC	COM	690145107	6,514	114,595	SH		DFND	10	0	85,115	29,480
OWENS CORNING NEW	COM	690742101	1,315	17,351	SH		DFND	4,9	0	17,351	0
OZON HLDGS PLC	SPONSORED ADS	69269L104	8,096	195,358	SH		DFND	4,10	0	195,358	0
PACCAR INC	COM	693718108	14,078	163,199	SH		DFND	4,9	0	144,626	18,573
PACIFIC PREMIER BANCORP	COM	69478X105	241	7,702	SH		DFND	10	0	7,702	0
PACKAGING CORP AMER	COM	695156109	29,482	213,785	SH		DFND	4,9	0	150,164	63,621
PAGERDUTY INC	COM	69553P100	109,480	2,625,423	SH		DFND	10	0	2,527,446	97,977
PALO ALTO NETWORKS INC	COM	697435105	52,123	146,666	SH		DFND	4,9	0	81,523	65,143
PAN AMERN SILVER CORP	COM	697900108	1,690	49,057	SH		DFND	4,9,11	0	49,057	0
PARKER-HANNIFIN CORP	COM	701094104	222,276	815,970	SH		DFND	4,9,10	0	790,180	25,790
PARSLEY ENERGY INC	CL A	701877102	25,830	1,819,046	SH		DFND	2	0	1,819,046	0
PARSONS CORPORATION	COM	70202L102	1,215	33,378	SH		DFND	10	0	33,378	0
PATRICK INDS INC	COM	703343103	393	5,749	SH		DFND	10	0	5,749	0
PAYCHEX INC	COM	704326107	12,209	131,046	SH		DFND	4,9	0	131,046	0
PAYCOM SOFTWARE INC	COM	70432V102	18,422	40,733	SH		DFND	4,9	0	31,532	9,201
PAYLOCITY HLDG CORP	COM	70438V106	104,995	509,905	SH		DFND	10	0	452,301	57,604
PAYPAL HLDGS INC	COM	70450Y103	938,098	4,005,424	SH		DFND	4,9,10	0	3,932,594	72,830
PEBBLEBROOK HOTEL TR	COM	70509V100	31,369	1,668,133	SH		DFND	4,10,12	0	1,607,096	61,037
PEGASYSTEMS INC	COM	705573103	15,643	117,389	SH		DFND	9	0	63,368	54,021
PELOTON INTERACTIVE INC	CL A COM	70614W100	59,016	388,982	SH		DFND	4,9,10	0	377,949	11,033
PEMBINA PIPELINE CORP	COM	706327103	2,899	122,648	SH		DFND	4,9	0	122,648	0
PENNANT GROUP INC	COM	70805E109	315	5,421	SH		DFND	10	0	5,421	0
PENNYMAC FINL SVCS INC NEW	COM	70932M107	388	5,911	SH		DFND	10	0	5,911	0
PENTAIR PLC	SHS	G7S00T104	2,713	51,083	SH		DFND	4,9	0	51,083	0
PENUMBRA INC	COM	70975L107	2,467	14,098	SH		DFND	9,10	0	14,098	0
PEOPLES UNITED FINANCIAL INC	COM	712704105	557	43,099	SH		DFND	9	0	15,505	27,594
PEPSICO INC	COM	713448108	186,746	1,259,358	SH		DFND	2,4,9,10	0	728,247	531,111
PERKINELMER INC	COM	714046109	463,587	3,230,569	SH		DFND	4,9,10	0	3,129,449	101,120
PERRIGO CO PLC	SHS	G97822103	1,655	36,997	SH		DFND	4,9	0	35,851	1,146
PFIZER INC	COM	717081103	168,554	4,580,935	SH		DFND	2,4,9,10	0	4,299,052	281,883
PG&E CORP	COM	69331C108	1,918	153,993	SH		DFND	4,9	0	153,467	526
PGT INNOVATIONS INC	COM	69336V101	32,467	1,596,217	SH		DFND	2,10	0	1,596,217	0
PHATHOM PHARMACEUTICALS INC	COM	71722W107	64,396	1,938,436	SH		DFND	10	0	1,884,189	54,247
PHIBRO ANIMAL HEALTH CORP	CL A COM	71742Q106	14,372	740,085	SH		DFND	2	0	740,085	0
PHILIP MORRIS INTL INC	COM	718172109	27,542	332,771	SH		DFND	4,9	0	263,921	68,850
PHILLIPS 66	COM	718546104	26,650	381,052	SH		DFND	4,9	0	88,424	292,628
PHREESIA INC	COM	71944F106	34,103	628,504	SH		DFND	10	0	602,219	26,285
PHYSICIANS RLTY TR	COM	71943U104	27,530	1,545,340	SH		DFND	4,10	0	1,545,340	0
PINDUODUO INC	SPONSORED ADS	722304102	42,644	240,019	SH		DFND	9,10	0	70,690	169,329
PINNACLE FINL PARTNERS INC	COM	72346Q104	1,556	24,164	SH		DFND	2	0	24,164	0
PINNACLE WEST CAP CORP	COM	723484101	14,178	177,334	SH		DFND	4,9	0	166,804	10,530
PINTEREST INC	CL A	72352L106	80,615	1,222,860	SH		DFND	4,9	0	1,222,860	0
PIONEER NAT RES CO	COM	723787107	32,394	284,454	SH		DFND	2,4,9,10	0	265,715	18,739
PLANET FITNESS INC	CL A	72703H101	738	9,508	SH		DFND	10	0	9,508	0
PNC FINL SVCS GROUP INC	COM	693475105	18,877	126,707	SH		DFND	2,4,9	0	114,599	12,108
POLARIS INC	COM	731068102	456	4,788	SH		DFND	4	0	4,788	0
POOL CORP	COM	73278L105	8,953	24,034	SH		DFND	4,9	0	24,034	0
POPULAR INC	COM NEW	733174700	308	5,471	SH		DFND	9	0	1,321	4,150
PPG INDS INC	COM	693506107	8,936	61,950	SH		DFND	4,9,10	0	61,279	671
PPL CORP	COM	69351T106	15,203	539,142	SH		DFND	2,4,9	0	390,757	148,385
PQ GROUP HLDGS INC	COM	73943T103	894	62,682	SH		DFND	10	0	62,682	0
PRA HEALTH SCIENCES INC	COM	69354M108	301,296	2,401,911	SH		DFND	10	0	2,341,039	60,872
PRAXIS PRECISION MEDICINES I	COM	74006W108	49,366	897,372	SH		DFND	10	0	873,740	23,632
PRESTIGE CONSMR HEALTHCARE I	COM	74112D101	23,318	668,708	SH		DFND	10	0	641,072	27,636
PRETIUM RES INC	COM	74139C102	347	30,270	SH		DFND	11	0	30,270	0
PRICE T ROWE GROUP INC	COM	74144T108	236,395	1,561,519	SH		DFND	4,9	0	571,594	989,925
PRIMERICA INC	COM	74164M108	241	1,802	SH		DFND	10	0	1,802	0
PRINCIPAL FINANCIAL GROUP IN	COM	74251V102	3,855	77,741	SH		DFND	4,9	0	77,741	0
PROCTER AND GAMBLE CO	COM	742718109	1,807,482	12,990,893	SH		DFND	2,4,9,10	0	11,377,317	1,613,576
PROGRESSIVE CORP	COM	743315103	1,167,790	11,810,620	SH		DFND	4,9,10	0	10,419,354	1,391,266
PROLOGIS INC.	COM	74340W103	141,026	1,415,135	SH		DFND	4,9,10,12	0	1,371,148	43,987
PROSPERITY BANCSHARES INC	COM	743606105	62,332	898,668	SH		DFND	2	0	898,668	0
PROTO LABS INC	COM	743713109	505	3,289	SH		DFND	10	0	3,289	0
PRUDENTIAL FINL INC	COM	744320102	7,630	97,741	SH		DFND	4,9	0	97,741	0
PTC INC	COM	69370C100	2,329	19,480	SH		DFND	4,9	0	19,480	0
PTC THERAPEUTICS INC	COM	69366J200	182,875	2,996,421	SH		DFND	10	0	2,893,717	102,704
PUBLIC STORAGE	COM	74460D109	129,149	559,270	SH		DFND	2,4,9	0	424,000	135,270
PUBLIC SVC ENTERPRISE GRP IN	COM	744573106	9,031	154,922	SH		DFND	4,9	0	154,922	0
PULMONX CORP	COM	745848101	25,835	374,313	SH		DFND	10	0	359,123	15,190
PULTE GROUP INC	COM	745867101	69,296	1,607,049	SH		DFND	4,9,10	0	1,524,207	82,842
QIAGEN NV	SHS NEW	N72482123	7,432	140,626	SH		DFND	9	0	118,627	21,999
QIAGEN NV	SHS NEW	N72482123	7,559	145,041	SH		DFND	4,9	0	62,772	82,269
QORVO INC	COM	74736K101	130,396	784,542	SH		DFND	4,9	0	770,225	14,317
QUALCOMM INC	COM	747525103	819,804	5,381,500	SH		DFND	4,9,10	0	4,237,718	1,143,782
QUALYS INC	COM	74758T303	1,678	13,765	SH		DFND	10	0	13,765	0
QUANTA SVCS INC	COM	74762E102	5,952	82,639	SH		DFND	9	0	82,639	0
QUANTUMSCAPE CORP	COM CL A	74767V109	762,510	9,029,133	SH		DFND	10	0	9,024,948	4,185
QUEST DIAGNOSTICS INC	COM	74834L100	165,557	1,389,246	SH		DFND	2,4,9,10	0	1,036,912	352,334
QUIDEL CORP	COM	74838J101	49,350	274,699	SH		DFND	9,10	0	260,927	13,772
QURATE RETAIL INC	COM SER A	74915M100	29,620	2,700,068	SH		DFND	2,9	0	2,700,068	0
RALPH LAUREN CORP	CL A	751212101	6,178	59,572	SH		DFND	4,9	0	59,409	163
RAYMOND JAMES FINL INC	COM	754730109	3,080	32,193	SH		DFND	4,9	0	32,193	0
RAYTHEON TECHNOLOGIES CORP	COM	75513E101	132,345	1,850,584	SH		DFND	2,4,9	0	1,443,941	406,643
RBC BEARINGS INC	COM	75524B104	553	3,086	SH		DFND	10	0	3,086	0
REALPAGE INC	COM	75606N109	257,682	2,953,709	SH		DFND	10	0	2,842,449	111,260
REALTY INCOME CORP	COM	756109104	9,417	151,491	SH		DFND	4,9	0	147,726	3,765
REATA PHARMACEUTICALS INC	CL A	75615P103	6,130	49,591	SH		DFND	9,10	0	24,017	25,574
REDBALL ACQUISITION CORP	UNIT 99/99/9999	G7417R121	22,973	1,987,252	SH		DFND	10	0	1,987,252	0
REDFIN CORP	COM	75737F108	72,567	1,057,360	SH		DFND	10	0	1,021,862	35,498
REGAL BELOIT CORP	COM	758750103	1,594	12,980	SH		DFND	9	0	12,980	0
REGENCY CTRS CORP	COM	758849103	1,991	43,674	SH		DFND	4,9	0	43,674	0
REGENERON PHARMACEUTICALS	COM	75886F107	184,457	381,823	SH		DFND	4,9,10	0	223,701	158,122
REGIONS FINANCIAL CORP NEW	COM	7591EP100	51,106	3,170,401	SH		DFND	2,4,9	0	3,170,401	0
REINSURANCE GRP OF AMERICA I	COM NEW	759351604	16,144	139,291	SH		DFND	4,9	0	21,464	117,827
RELAY THERAPEUTICS INC	COM	75943R102	4,077	98,092	SH		DFND	10	0	64,291	33,801
RELIANCE STEEL & ALUMINUM CO	COM	759509102	8,185	68,352	SH		DFND	4,9	0	36,720	31,632
RENAISSANCERE HLDGS LTD	COM	G7496G103	77,835	469,393	SH		DFND	2,4,9	0	439,079	30,314
REPAY HLDGS CORP	COM CL A	76029L100	25,184	924,184	SH		DFND	10	0	888,888	35,296
REPLIGEN CORP	COM	759916109	4,377	22,839	SH		DFND	9	0	19,943	2,896
REPUBLIC SVCS INC	COM	760759100	50,701	526,497	SH		DFND	2,4,9	0	367,952	158,545
RESMED INC	COM	761152107	265,771	1,250,324	SH		DFND	4,9	0	409,521	840,803
RESTAURANT BRANDS INTL INC	COM	76131D103	3,836	62,750	SH		DFND	4,9	0	62,750	0
REXFORD INDL RLTY INC	COM	76169C100	50,139	1,021,253	SH		DFND	4,10,12	0	984,293	36,960
REXNORD CORP	COM	76169B102	439,857	11,138,450	SH		DFND	10	0	10,764,635	373,815
REYNOLDS CONSUMER PRODS INC	COM	76171L106	27,212	905,874	SH		DFND	10	0	905,874	0
RHYTHM PHARMACEUTICALS INC	COM	76243J105	133,542	4,491,765	SH		DFND	10	0	4,357,432	134,333
RINGCENTRAL INC	CL A	76680R206	459,587	1,212,726	SH		DFND	4,9,10	0	930,505	282,221
RITCHIE BROS AUCTIONEERS	COM	767744105	424	6,102	SH		DFND	4,9	0	6,102	0
RITCHIE BROS AUCTIONEERS	COM	767744105	434,814	6,251,823	SH		DFND	10	0	6,050,446	201,377
RLI CORP	COM	749607107	43,958	422,062	SH		DFND	10	0	398,498	23,564
ROBERT HALF INTL INC	COM	770323103	31,778	508,616	SH		DFND	4,9	0	48,441	460,175
ROCKET PHARMACEUTICALS INC	COM	77313F106	70,043	1,277,310	SH		DFND	10	0	1,240,908	36,402
ROCKWELL AUTOMATION INC	COM	773903109	180,305	718,892	SH		DFND	4,9,10	0	423,622	295,270
ROGERS COMMUNICATIONS INC	CL B	775109200	8,455	181,737	SH		DFND	2,4,9	0	144,627	37,110
ROGERS CORP	COM	775133101	126,956	817,543	SH		DFND	2,10	0	793,484	24,059
ROKU INC	COM CL A	77543R102	179,670	541,143	SH		DFND	4,9,10	0	501,734	39,409
ROLLINS INC	COM	775711104	32,578	833,850	SH		DFND	4,9,10	0	527,843	306,007
ROPER TECHNOLOGIES INC	COM	776696106	85,799	199,073	SH		DFND	4,9	0	188,488	10,585
ROSS STORES INC	COM	778296103	38,889	316,638	SH		DFND	2,4,9	0	312,612	4,026
ROYAL BK CDA	COM	780087102	64,428	785,078	SH		DFND	4,9	0	494,327	290,751
ROYAL CARIBBEAN GROUP	COM	V7780T103	30,814	412,580	SH		DFND	4,9	0	390,022	22,558
ROYAL DUTCH SHELL PLC	SPON ADR B	780259107	275	8,168	SH		DFND	4	0	8,168	0
ROYALTY PHARMA PLC	SHS CLASS A	G7709Q104	245,330	4,901,700	SH		DFND	4,9,10	0	4,746,323	155,377
RPM INTL INC	COM	749685103	13,354	147,099	SH		DFND	4,9	0	88,437	58,662
RYANAIR HOLDINGS PLC	SPONSORED ADS	783513203	318,467	2,895,682	SH		DFND	10	0	2,803,346	92,336
S&P GLOBAL INC	COM	78409V104	190,710	580,198	SH		DFND	4,9,10	0	580,198	0
SABRA HEALTH CARE REIT INC	COM	78573L106	42,578	2,450,564	SH		DFND	4,10,12	0	2,368,189	82,375
SABRE CORP	COM	78573M104	4,379	364,145	SH		DFND	4,9	0	363,366	779
SAFEGUARD SCIENTIFICS INC	COM NEW	786449207	1,232	192,633	SH		DFND	4,10	0	192,633	0
SAFEHOLD INC	COM	78645L100	1,143	15,774	SH		DFND	10	0	15,774	0
SAGE THERAPEUTICS INC	COM	78667J108	171,190	1,978,811	SH		DFND	10	0	1,915,338	63,473
SAIA INC	COM	78709Y105	185,981	1,028,653	SH		DFND	10	0	993,012	35,641
SAILPOINT TECHNOLOGIES HLDGS	COM	78781P105	112,335	2,109,970	SH		DFND	10	0	1,791,266	318,704
SALESFORCE COM INC	COM	79466L302	1,951,344	8,770,652	SH		DFND	4,9,10	0	8,017,135	753,517
SANDERSON FARMS INC	COM	800013104	46,711	353,337	SH		DFND	2	0	353,337	0
SANOFI	SPONSORED ADR	80105N105	25,392	522,591	SH		DFND	4,10	0	522,591	0
SANTANDER CONSUMER USA HDG I	COM	80283M101	2,116	96,109	SH		DFND	9	0	92,514	3,595
SAREPTA THERAPEUTICS INC	COM	803607100	660,758	3,875,676	SH		DFND	4,9,10	0	3,768,204	107,472
SBA COMMUNICATIONS CORP NEW	CL A	78410G104	60,601	214,803	SH		DFND	4,9,10,12	0	181,445	33,358
SCHLUMBERGER LTD	COM	806857108	13,779	631,289	SH		DFND	2,4,9	0	631,289	0
SCHWAB CHARLES CORP	COM	808513105	252,074	4,752,556	SH		DFND	2,4,9,10	0	4,623,118	129,438
SCHWAB STRATEGIC TR	US TIPS ETF	808524870	4,495	72,414	SH		DFND	10	0	72,414	0
SCIENCE APPLICATIONS INTL CO	COM	808625107	1,051	11,101	SH		DFND	9	0	5,488	5,613
SCION TECH GROWTH I	UNIT 12/17/2025	G31067120	209	20,000	SH		DFND	4	0	20,000	0
SCOTTS MIRACLE GRO CO	CL A	810186106	4,516	22,677	SH		DFND	4,9,10	0	22,582	95
SEA LTD	SPONSORD ADS	81141R100	4,976	24,998	SH		DFND	4,10,12	0	24,998	0
SEAGATE TECHNOLOGY PLC	SHS	G7945M107	121,012	1,946,789	SH		DFND	4,9	0	795,793	1,150,996
SEAGEN INC	COM	81181C104	47,939	273,707	SH		DFND	4,9	0	114,029	159,678
SEALED AIR CORP NEW	COM	81211K100	486,680	10,628,522	SH		DFND	4,9,10	0	10,329,434	299,088
SEI INVTS CO	COM	784117103	2,422	42,139	SH		DFND	4,9	0	41,490	649
SELECT SECTOR SPDR TR	ENERGY	81369Y506	3,723	98,235	SH		DFND	10	0	98,235	0
SELECT SECTOR SPDR TR	SBI INT-FINL	81369Y605	2,536	86,022	SH		DFND	10	0	86,022	0
SELECT SECTOR SPDR TR	SBI INT-INDS	81369Y704	4,178	47,180	SH		DFND	10	0	47,180	0
SELECT SECTOR SPDR TR	SBI MATERIALS	81369Y100	1,954	26,987	SH		DFND	10	0	26,987	0
SELECTIVE INS GROUP INC	COM	816300107	88,448	1,320,508	SH		DFND	10	0	1,288,028	32,480
SELECTQUOTE INC	COM	816307300	275	13,272	SH		DFND	10	0	13,272	0
SEMPRA ENERGY	COM	816851109	138,408	1,086,338	SH		DFND	4,9,10	0	1,067,138	19,200
SENSATA TECHNOLOGIES HLDG PL	SHS	G8060N102	545,822	10,349,230	SH		DFND	4,9,10	0	10,047,887	301,343
SENSIENT TECHNOLOGIES CORP	COM	81725T100	299,221	4,056,127	SH		DFND	10	0	3,894,759	161,368
SERES THERAPEUTICS INC	COM	81750R102	64,810	2,645,274	SH		DFND	10	0	2,571,517	73,757
SERVICENOW INC	COM	81762P102	219,012	397,896	SH		DFND	4,9,10	0	394,155	3,741
SHAKE SHACK INC	CL A	819047101	800	9,435	SH		DFND	10	0	9,435	0
SHATTUCK LABS INC	COM	82024L103	79,211	1,642,110	SH		DFND	10	0	1,642,110	0
SHAW COMMUNICATIONS INC	CL B CONV	82028K200	26,220	1,495,151	SH		DFND	4,9	0	731,816	763,335
SHERWIN WILLIAMS CO	COM	824348106	926,862	1,261,162	SH		DFND	4,9,10	0	1,225,758	35,404
SHIFT4 PMTS INC	CL A	82452J109	11,929	158,205	SH		DFND	10	0	151,834	6,371
SHOPIFY INC	CL A	82509L107	26,535	23,505	SH		DFND	4,9	0	23,505	0
SHOTSPOTTER INC	COM	82536T107	733	19,451	SH		DFND	10	0	19,451	0
SHUTTERSTOCK INC	COM	825690100	23,424	326,699	SH		DFND	2	0	326,699	0
SILK RD MED INC	COM	82710M100	60,730	964,281	SH		DFND	10	0	935,041	29,240
SIMON PPTY GROUP INC NEW	COM	828806109	6,788	79,627	SH		DFND	4,9	0	79,627	0
SIMPLY GOOD FOODS CO	COM	82900L102	96,468	3,076,156	SH		DFND	10	0	2,989,663	86,493
SIMPSON MANUFACTURING CO INC	COM	829073105	499	5,338	SH		DFND	10	0	5,338	0
SIMULATIONS PLUS INC	COM	829214105	2,023	28,124	SH		DFND	10	0	28,124	0
SIRIUS XM HOLDINGS INC	COM	82968B103	3,217	505,598	SH		DFND	4,9,10	0	505,598	0
SITEONE LANDSCAPE SUPPLY INC	COM	82982L103	863	5,438	SH		DFND	10	0	5,438	0
SK TELECOM LTD	SPONSORED ADR	78440P108	37,652	1,539,019	SH		DFND	4,12	0	1,539,019	0
SKECHERS U S A INC	CL A	830566105	661	18,389	SH		DFND	4,10	0	18,389	0
SKYLINE CHAMPION CORPORATION	COM	830830105	26,615	860,209	SH		DFND	2,10	0	860,209	0
SKYWORKS SOLUTIONS INC	COM	83088M102	37,591	245,895	SH		DFND	4,9	0	179,458	66,437
SLACK TECHNOLOGIES INC	COM CL A	83088V102	2,226	52,693	SH		DFND	4,9	0	52,693	0
SLM CORP	COM	78442P106	431	34,759	SH		DFND	9	0	31,193	3,566
SMARTSHEET INC	COM CL A	83200N103	221	3,195	SH		DFND	9	0	2,859	336
SMITH A O CORP	COM	831865209	13,158	240,022	SH		DFND	4,9	0	108,513	131,509
SMUCKER J M CO	COM NEW	832696405	47,489	410,811	SH		DFND	2,4,9	0	263,886	146,925
SNAP INC	CL A	83304A106	934,773	18,669,408	SH		DFND	4,9,10	0	17,196,560	1,472,848
SNAP ON INC	COM	833034101	10,821	63,231	SH		DFND	4,9	0	51,938	11,293
SNOWFLAKE INC	CL A	833445109	469	1,666	SH		DFND	4,9	0	1,666	0
SOLAREDGE TECHNOLOGIES INC	COM	83417M104	9,108	28,534	SH		DFND	4,9	0	17,722	10,812
SONOCO PRODS CO	COM	835495102	52,357	883,660	SH		DFND	2,9	0	813,576	70,084
SONY CORP	SPONSORED ADR	835699307	314	3,101	SH		DFND	10	0	3,101	0
SOTERA HEALTH CO	COM	83601L102	96,159	3,504,350	SH		DFND	10	0	3,410,542	93,808
SOUTHERN CO	COM	842587107	132,125	2,150,885	SH		DFND	4,9	0	1,225,940	924,945
SOUTHERN COPPER CORP	COM	84265V105	3,790	58,197	SH		DFND	4,9	0	58,197	0
SOUTHWEST AIRLS CO	COM	844741108	23,922	513,249	SH		DFND	4,9,10	0	513,249	0
SOUTHWEST GAS HOLDINGS INC	COM	844895102	68,109	1,121,135	SH		DFND	2	0	1,121,135	0
SPDR S&P 500 ETF TR	TR UNIT	78462F103	299	800	SH		DFND	10	0	800	0
SPDR SER TR	S&P HOMEBUILD	78464A888	793	13,758	SH		DFND	10	0	13,758	0
SPECTRUM BRANDS HLDGS INC NE	COM	84790A105	3,556	45,020	SH		DFND	4,9	0	21,450	23,570
SPIRIT RLTY CAP INC NEW	COM NEW	84860W300	40,330	1,003,756	SH		DFND	4,9,10,12	0	908,065	95,691
SPLUNK INC	COM	848637104	100,814	593,404	SH		DFND	4,9,10	0	224,557	368,847
SPOTIFY TECHNOLOGY S A	SHS	L8681T102	10,512	33,405	SH		DFND	4,9	0	26,978	6,427
SPROUTS FMRS MKT INC	COM	85208M102	5,899	293,482	SH		DFND	9	0	185,980	107,502
SPS COMMERCE INC	COM	78463M107	3,778	34,792	SH		DFND	10	0	34,792	0
SPX CORP	COM	784635104	29,332	537,816	SH		DFND	4,10	0	489,444	48,372
SQUARE INC	CL A	852234103	18,420	84,620	SH		DFND	4,9	0	84,620	0
SS&C TECHNOLOGIES HLDGS INC	COM	78467J100	1,336,088	18,365,283	SH		DFND	4,9,10	0	17,906,178	459,105
SSR MNG INC	COM	784730103	8,049	400,815	SH		DFND	9,11	0	400,815	0
STAG INDL INC	COM	85254J102	102,794	3,282,040	SH		DFND	2,10	0	3,282,040	0
STANDEX INTL CORP	COM	854231107	19,672	253,767	SH		DFND	10	0	253,767	0
STANLEY BLACK & DECKER INC	COM	854502101	25,627	143,526	SH		DFND	4,9,10	0	143,526	0
STARBUCKS CORP	COM	855244109	469,974	4,393,040	SH		DFND	2,4,9,10	0	4,137,179	255,861
STATE STR CORP	COM	857477103	9,145	125,657	SH		DFND	4,9	0	87,414	38,243
STEEL DYNAMICS INC	COM	858119100	1,722	46,710	SH		DFND	4,9	0	46,710	0
STERIS PLC	SHS USD	G8473T100	616,630	3,253,302	SH		DFND	4,9,10	0	3,139,611	113,691
STERLING BANCORP DEL	COM	85917A100	285	15,861	SH		DFND	10	0	15,861	0
STONERIDGE INC	COM	86183P102	51,073	1,689,494	SH		DFND	2	0	1,689,494	0
STORE CAP CORP	COM	862121100	215	6,314	SH		DFND	10	0	6,314	0
STRIDE INC	COM	86333M108	19,962	940,281	SH		DFND	10	0	900,648	39,633
STRYKER CORPORATION	COM	863667101	322,629	1,316,657	SH		DFND	2,4,9,10	0	1,303,604	13,053
SUMMIT MATLS INC	CL A	86614U100	107,444	5,350,782	SH		DFND	10	0	5,255,153	95,629
SUN CMNTYS INC	COM	866674104	80,427	529,494	SH		DFND	4,9,10,12	0	514,392	15,102
SUN LIFE FINANCIAL INC.	COM	866796105	14,936	336,154	SH		DFND	4,9	0	214,635	121,519
SUNCOR ENERGY INC NEW	COM	867224107	26,387	1,574,216	SH		DFND	4,9,10	0	1,516,995	57,221
SUNRUN INC	COM	86771W105	445	6,414	SH		DFND	4,9	0	6,414	0
SUNSTONE HOTEL INVS INC NEW	COM	867892101	75,491	6,662,896	SH		DFND	2	0	6,662,896	0
SUPERNUS PHARMACEUTICALS INC	COM	868459108	1,870	74,343	SH		DFND	10	0	74,343	0
SURMODICS INC	COM	868873100	19,284	443,102	SH		DFND	10	0	409,932	33,170
SUTRO BIOPHARMA INC	COM	869367102	3,962	182,913	SH		DFND	10	0	182,913	0
SVB FINANCIAL GROUP	COM	78486Q101	268,978	693,552	SH		DFND	4,9,10	0	671,891	21,661
SYNCHRONY FINANCIAL	COM	87165B103	164,329	4,734,396	SH		DFND	2,4,9,10	0	2,115,196	2,619,200
SYNDAX PHARMACEUTICALS INC	COM	87164F105	2,901	130,458	SH		DFND	10	0	130,458	0
SYNEOS HEALTH INC	CL A	87166B102	7,412	108,797	SH		DFND	9,10	0	75,010	33,787
SYNNEX CORP	COM	87162W100	1,481	18,185	SH		DFND	10	0	18,185	0
SYNOPSYS INC	COM	871607107	104,843	404,440	SH		DFND	2,4,9	0	296,430	108,010
SYSCO CORP	COM	871829107	364,985	4,914,965	SH		DFND	4,9,10	0	3,069,233	1,845,732
TACTILE SYS TECHNOLOGY INC	COM	87357P100	1,232	27,408	SH		DFND	10	0	27,408	0
TAIWAN SEMICONDUCTOR MFG LTD	SPONSORED ADS	874039100	711,307	6,523,527	SH		DFND	4,10,12	0	6,259,509	264,018
TAKEDA PHARMACEUTICAL CO LTD	SPONSORED ADS	874060205	10,599	582,351	SH		DFND	10	0	582,351	0
TAKE-TWO INTERACTIVE SOFTWAR	COM	874054109	252,197	1,213,710	SH		DFND	4,9	0	566,853	646,857
TAL EDUCATION GROUP	SPONSORED ADS	874080104	8,344	116,680	SH		DFND	9	0	34,882	81,798
TAPESTRY INC	COM	876030107	16,091	517,725	SH		DFND	9	0	479,360	38,365
TARGET CORP	COM	87612E106	461,663	2,615,294	SH		DFND	4,9,10	0	1,695,528	919,766
TC ENERGY CORP	COM	87807B107	8,948	220,265	SH		DFND	4,9	0	220,265	0
TE CONNECTIVITY LTD	REG SHS	H84989104	792,840	6,548,416	SH		DFND	4,9,10	0	6,398,284	150,132
TECK RESOURCES LTD	CL B	878742204	147,837	8,153,403	SH		DFND	4,9,10,11	0	8,081,271	72,132
TELADOC HEALTH INC	COM	87918A105	60,569	302,907	SH		DFND	4,9	0	105,664	197,243
TELEDYNE TECHNOLOGIES INC	COM	879360105	509,437	1,299,648	SH		DFND	4,9,10	0	1,264,829	34,819
TELEFLEX INCORPORATED	COM	879369106	373,797	908,221	SH		DFND	4,9,10	0	876,699	31,522
TELUS CORPORATION	COM	87971M103	23,316	1,179,026	SH		DFND	4	0	1,135,966	43,060
TENCENT MUSIC ENTMT GROUP	SPON ADS	88034P109	372	19,346	SH		DFND	9	0	19,346	0
TERADYNE INC	COM	880770102	3,872	32,294	SH		DFND	4,9	0	32,294	0
TERMINIX GLOBAL HOLDINGS INC	COM	88087E100	897,154	17,587,808	SH		DFND	9,10	0	17,090,993	496,815
TESLA INC	COM	88160R101	252,542	357,962	SH		DFND	4,9,10	0	328,874	29,088
TEVA PHARMACEUTICAL INDS LTD	SPONSORED ADS	881624209	1,961	203,147	SH		DFND	4,9	0	203,147	0
TEXAS CAP BANCSHARES INC	COM	88224Q107	245	4,120	SH		DFND	10	0	4,120	0
TEXAS INSTRS INC	COM	882508104	2,277,864	13,878,442	SH		DFND	4,9,10	0	12,539,894	1,338,548
TEXAS ROADHOUSE INC	COM	882681109	631	8,074	SH		DFND	10	0	8,074	0
TEXTRON INC	COM	883203101	1,067	22,087	SH		DFND	4,9	0	22,087	0
THE PROVIDENCE SERVICE CORP	COM	743815102	37,985	274,006	SH		DFND	10	0	263,194	10,812
THE TRADE DESK INC	COM CL A	88339J105	204,611	255,442	SH		DFND	4,9,10	0	218,945	36,497
THERAPEUTICS ACQUISITION COR	COM CL A	88339T103	1,729	123,707	SH		DFND	10	0	123,707	0
THERMO FISHER SCIENTIFIC INC	COM	883556102	1,033,841	2,219,677	SH		DFND	4,9,10	0	2,182,219	37,458
THERMON GROUP HLDGS INC	COM	88362T103	22,854	1,462,201	SH		DFND	2	0	1,462,201	0
THOMSON REUTERS CORP.	COM NEW	884903709	7,858	96,076	SH		DFND	4,9	0	96,076	0
THOR INDS INC	COM	885160101	77,501	833,438	SH		DFND	10	0	801,727	31,711
TIFFANY & CO NEW	COM	886547108	74,713	568,377	SH		DFND	4,9,10	0	254,779	313,598
TJX COS INC NEW	COM	872540109	46,804	685,272	SH		DFND	4,9	0	663,665	21,607
T-MOBILE US INC	COM	872590104	1,232,397	9,139,085	SH		DFND	4,9,10	0	8,691,354	447,731
TOLL BROTHERS INC	COM	889478103	400	9,200	SH		DFND	4,10	0	9,200	0
TOPBUILD CORP	COM	89055F103	706	3,838	SH		DFND	10	0	3,838	0
TORO CO	COM	891092108	20,777	219,075	SH		DFND	9	0	127,608	91,467
TORONTO DOMINION BK ONT	COM NEW	891160509	71,331	1,263,959	SH		DFND	4,9,10	0	655,220	608,739
TRACTOR SUPPLY CO	COM	892356106	9,149	65,072	SH		DFND	4,9	0	65,072	0
TRADEWEB MKTS INC	CL A	892672106	887	14,197	SH		DFND	4,9	0	14,197	0
TRANE TECHNOLOGIES PLC	SHS	G8994E103	166,880	1,149,639	SH		DFND	4,9,10	0	634,516	515,123
TRANSDIGM GROUP INC	COM	893641100	186,229	300,927	SH		DFND	4,9	0	215,104	85,823
TRANSUNION	COM	89400J107	40,477	407,958	SH		DFND	4,9	0	46,556	361,402
TRAVELERS COMPANIES INC	COM	89417E109	178,166	1,269,269	SH		DFND	4,9,10	0	1,255,969	13,300
TRAVERE THERAPEUTICS INC	COM	89422G107	111,297	4,083,553	SH		DFND	10	0	3,960,381	123,172
TREX CO INC	COM	89531P105	1,192	14,232	SH		DFND	10	0	14,232	0
TRIMBLE INC	COM	896239100	105,487	1,578,805	SH		DFND	4,9	0	1,578,320	485
TRINET GROUP INC	COM	896288107	96,688	1,199,599	SH		DFND	4,10	0	1,160,333	39,266
TRINITY INDS INC	COM	896522109	202	7,668	SH		DFND	9	0	1,855	5,813
TRIP COM GROUP LTD	ADS	89677Q107	592	17,537	SH		DFND	9	0	17,537	0
TRIPADVISOR INC	COM	896945201	1,682	58,445	SH		DFND	9	0	32,104	26,341
TRUIST FINL CORP	COM	89832Q109	27,778	579,577	SH		DFND	2,4,9	0	480,506	99,071
TWILIO INC	CL A	90138F102	518,031	1,530,372	SH		DFND	4,9,10	0	1,227,146	303,226
TWITTER INC	COM	90184L102	82,877	1,530,509	SH		DFND	4,9,10	0	1,191,138	339,371
TWITTER INC	NOTE 0.250% 6/1	90184LAF9	8,723	7,203,000	SH		DFND	4	0	7,203,000	0
TYLER TECHNOLOGIES INC	COM	902252105	321,959	737,560	SH		DFND	4,9,10	0	645,953	91,607
TYSON FOODS INC	CL A	902494103	71,637	1,111,707	SH		DFND	2,4,9,10	0	1,005,151	106,556
UBER TECHNOLOGIES INC	COM	90353T100	519,688	10,189,705	SH		DFND	4,9,10	0	9,848,263	341,442
UBIQUITI INC	COM	90353W103	7,443	26,724	SH		DFND	9,10	0	26,659	65
UBS GROUP AG	SHS	H42097107	63,500	4,500,521	SH		DFND	4,9	0	2,826,981	1,673,540
UBS GROUP AG	SHS	H42097107	4	266	SH		DFND	4	0	266	0
UDR INC	COM	902653104	58,437	1,520,998	SH		DFND	4,9,10,12	0	1,471,825	49,173
UFP INDUSTRIES INC	COM	90278Q108	418	7,520	SH		DFND	10	0	7,520	0
UFP TECHNOLOGIES INC	COM	902673102	279	5,991	SH		DFND	10	0	5,991	0
UGI CORP NEW	COM	902681105	1,136	32,484	SH		DFND	4,9	0	32,484	0
ULTA BEAUTY INC	COM	90384S303	14,159	49,304	SH		DFND	4,9	0	33,300	16,004
UNDER ARMOUR INC	CL C	904311206	149,180	10,025,506	SH		DFND	10	0	10,000,079	25,427
UNIFIRST CORP MASS	COM	904708104	106,284	502,073	SH		DFND	2	0	502,073	0
UNILEVER PLC	SPON ADR NEW	904767704	375	6,214	SH		DFND	4	0	6,214	0
UNION PAC CORP	COM	907818108	228,807	1,099,295	SH		DFND	2,4,9,10	0	963,330	135,965
UNIQURE NV	SHS	N90064101	25,466	704,838	SH		DFND	10	0	688,982	15,856
UNITED AIRLS HLDGS INC	COM	910047109	2,156	49,850	SH		DFND	4,9	0	49,850	0
UNITED BANKSHARES INC WEST V	COM	909907107	81,492	2,515,177	SH		DFND	2	0	2,515,177	0
UNITED CMNTY BKS BLAIRSVLE G	COM	90984P303	93,226	3,277,982	SH		DFND	2	0	3,277,982	0
UNITED PARCEL SERVICE INC	CL B	911312106	937,646	5,568,083	SH		DFND	2,4,9,10	0	4,588,762	979,321
UNITED RENTALS INC	COM	911363109	4,725	20,373	SH		DFND	4,9	0	20,373	0
UNITED THERAPEUTICS CORP DEL	COM	91307C102	2,848	18,765	SH		DFND	9	0	13,023	5,742
UNITEDHEALTH GROUP INC	COM	91324P102	1,697,681	4,841,206	SH		DFND	4,9,10	0	4,713,173	128,033
UNIVAR SOLUTIONS USA INC	COM	91336L107	5,563	292,536	SH		DFND	4	0	292,536	0
UNIVERSAL DISPLAY CORP	COM	91347P105	89,991	391,533	SH		DFND	4,10	0	391,533	0
UNIVERSAL HLTH SVCS INC	CL B	913903100	2,158	15,694	SH		DFND	4,9	0	15,428	266
US BANCORP DEL	COM NEW	902973304	22,307	478,813	SH		DFND	2,4,9,10	0	433,626	45,187
V F CORP	COM	918204108	150,954	1,767,448	SH		DFND	4,9,10	0	1,511,029	256,419
VAIL RESORTS INC	COM	91879Q109	65,732	235,632	SH		DFND	4,9	0	58,435	177,197
VALERO ENERGY CORP	COM	91913Y100	49,717	878,887	SH		DFND	4,9	0	131,663	747,224
VALVOLINE INC	COM	92047W101	53,167	2,297,633	SH		DFND	9,10	0	2,197,566	100,067
VANDA PHARMACEUTICALS INC	COM	921659108	1,014	77,171	SH		DFND	10	0	77,171	0
VANGUARD CHARLOTTE FDS	INTL BD IDX ETF	92203J407	1,680	28,693	SH		DFND	10	0	28,693	0
VANGUARD INDEX FDS	S&P 500 ETF SHS	922908363	111,125	323,330	SH		DFND	10	0	323,330	0
VANGUARD INDEX FDS	SMALL CP ETF	922908751	54,732	281,139	SH		DFND	10	0	281,139	0
VANGUARD INTL EQUITY INDEX F	ALLWRLD EX US	922042775	1,973	33,814	SH		DFND	10	0	33,814	0
VANGUARD INTL EQUITY INDEX F	FTSE EMR MKT ETF	922042858	1,663	33,188	SH		DFND	10	0	33,188	0
VANGUARD INTL EQUITY INDEX F	FTSE EUROPE ETF	922042874	29,184	484,468	SH		DFND	10	0	484,468	0
VANGUARD INTL EQUITY INDEX F	FTSE PACIFIC ETF	922042866	2,629	33,032	SH		DFND	10	0	33,032	0
VANGUARD SCOTTSDALE FDS	INTER TERM TREAS	92206C706	1,522	21,919	SH		DFND	10	0	21,919	0
VANGUARD SCOTTSDALE FDS	INT-TERM CORP	92206C870	3,271	33,677	SH		DFND	10	0	33,677	0
VANGUARD SCOTTSDALE FDS	MORTG-BACK SEC	92206C771	455	8,423	SH		DFND	10	0	8,423	0
VANGUARD WHITEHALL FDS	HIGH DIV YLD	921946406	550	6,007	SH		DFND	10	0	6,007	0
VANGUARD WORLD FDS	HEALTH CAR ETF	92204A504	1,934	8,646	SH		DFND	10	0	8,646	0
VANGUARD WORLD FDS	INDUSTRIAL ETF	92204A603	1,875	11,028	SH		DFND	10	0	11,028	0
VAREX IMAGING CORP	COM	92214X106	29,628	1,776,270	SH		DFND	2	0	1,776,270	0
VARIAN MED SYS INC	COM	92220P105	230,338	1,316,142	SH		DFND	4,9,10	0	1,269,491	46,651
VAXCYTE INC	COM	92243G108	107,538	4,196,778	SH		DFND	10	0	4,098,871	97,907
VECTRUS INC	COM	92242T101	22,061	443,701	SH		DFND	2	0	443,701	0
VEEVA SYS INC	CL A COM	922475108	184,621	678,119	SH		DFND	4,9	0	301,489	376,630
VENTAS INC	COM	92276F100	6,113	124,678	SH		DFND	4,9,10	0	124,678	0
VEREIT INC	COM	92339V308	44,864	1,187,036	SH		DFND	4,9,10,12	0	1,147,187	39,849
VERISIGN INC	COM	92343E102	122,555	566,678	SH		DFND	4,9	0	517,854	48,824
VERISK ANALYTICS INC	COM	92345Y106	379,334	1,827,333	SH		DFND	4,9,10	0	1,781,868	45,465
VERIZON COMMUNICATIONS INC	COM	92343V104	211,641	3,604,258	SH		DFND	4,9,10	0	3,058,991	545,267
VERTEX INC	CL A	92538J106	261	7,480	SH		DFND	10	0	7,480	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	984,704	4,166,534	SH		DFND	4,9,10	0	3,852,153	314,381
VESPER HEALTHCARE ACQSTN COR	COM CL A	92538T104	21,507	1,901,618	SH		DFND	10	0	1,901,618	0
VESPER HEALTHCARE ACQSTN COR	UNIT 99/99/9999	92538T203	177	14,596	SH		DFND	10	0	14,596	0
VIA OPTRONICS AG	SPONSORED ADS	91823Y109	4,007	300,000	SH		DFND	4	0	300,000	0
VIACOMCBS INC	CL B	92556H206	4,760	127,752	SH		DFND	4,9	0	127,752	0
VIATRIS INC	COM	92556V106	10,680	569,942	SH		DFND	4,9,10	0	492,672	77,270
VICI PPTYS INC	COM	925652109	537,231	21,066,530	SH		DFND	4,9,10,12	0	20,886,629	179,901
VIPSHOP HOLDINGS LIMITED	SPONSORED ADS A	92763W103	1,011	35,983	SH		DFND	9	0	35,983	0
VISA INC	COM CL A	92826C839	1,744,104	7,975,888	SH		DFND	4,9,10	0	7,074,464	901,424
VISHAY INTERTECHNOLOGY INC	COM	928298108	37,898	1,829,934	SH		DFND	2	0	1,829,934	0
VISTEON CORP	COM NEW	92839U206	346,660	2,761,794	SH		DFND	10	0	2,689,245	72,549
VISTRA CORP	COM	92840M102	34,870	1,773,656	SH		DFND	4,9,10	0	1,665,328	108,328
VITAL FARMS INC	COM	92847W103	552	21,818	SH		DFND	10	0	21,818	0
VIVINT SMART HOME INC	COM CL A	928542109	1,014	48,860	SH		DFND	10	0	48,860	0
VMWARE INC	CL A COM	928563402	2,887	20,579	SH		DFND	4,9	0	20,579	0
VODAFONE GROUP PLC NEW	SPONSORED ADR	92857W308	181	11,000	SH		DFND	4	0	11,000	0
VONAGE HLDGS CORP	COM	92886T201	206,445	16,034,551	SH		DFND	10	0	15,444,184	590,367
VONTIER CORPORATION	COM	928881101	329	9,838	SH		DFND	4	0	9,838	0
VORNADO RLTY TR	SH BEN INT	929042109	1,726	46,228	SH		DFND	4,9,10	0	46,228	0
VOYA FINANCIAL INC	COM	929089100	16,815	285,914	SH		DFND	4,9	0	51,612	234,302
VROOM INC	COM	92918V109	316	7,724	SH		DFND	10	0	7,724	0
VULCAN MATLS CO	COM	929160109	7,030	47,399	SH		DFND	2,4,9,10	0	47,194	205
WABTEC	COM	929740108	315,078	4,304,227	SH		DFND	4,9,10	0	4,184,411	119,816
WALGREENS BOOTS ALLIANCE INC	COM	931427108	7,835	196,537	SH		DFND	2,4,9	0	179,898	16,639
WALKER & DUNLOP INC	COM	93148P102	148,229	1,610,598	SH		DFND	4,10	0	1,571,356	39,242
WALMART INC	COM	931142103	336,778	2,336,404	SH		DFND	4,9,10	0	1,507,981	828,423
WARNER MUSIC GROUP CORP	COM CL A	934550203	89,242	2,349,095	SH		DFND	10	0	2,349,095	0
WARRIOR MET COAL INC	COM	93627C101	872	40,919	SH		DFND	10	0	40,919	0
WASHINGTON FED INC	COM	938824109	107,897	4,191,803	SH		DFND	2	0	4,191,803	0
WASHINGTON REAL ESTATE INVT	SH BEN INT	939653101	32,302	1,493,039	SH		DFND	4,10,12	0	1,439,874	53,165
WASTE CONNECTIONS INC	COM	94106B101	45,387	442,496	SH		DFND	2,4,9	0	442,496	0
WASTE CONNECTIONS INC	COM	94106B101	2,606	25,467	SH		DFND	4	0	25,467	0
WASTE MGMT INC DEL	COM	94106L109	65,054	551,633	SH		DFND	4,9,10	0	540,077	11,556
WATERS CORP	COM	941848103	355,549	1,437,025	SH		DFND	4,9,10	0	1,338,880	98,145
WATSCO INC	COM	942622200	5,218	23,033	SH		DFND	9	0	21,402	1,631
WATTS WATER TECHNOLOGIES INC	CL A	942749102	30,153	247,762	SH		DFND	2,4	0	247,762	0
WAYFAIR INC	CL A	94419L101	376,438	1,667,060	SH		DFND	4,9,10	0	1,595,147	71,913
WEC ENERGY GROUP INC	COM	92939U106	45,423	493,596	SH		DFND	4,9	0	317,224	176,372
WELLS FARGO CO NEW	COM	949746101	45,671	1,513,391	SH		DFND	2,4,9,10	0	1,280,184	233,207
WELLTOWER INC	COM	95040Q104	76,745	1,188,042	SH		DFND	4,9,10,12	0	1,151,561	36,481
WENDYS CO	COM	95058W100	93,526	4,266,686	SH		DFND	4,10	0	4,106,995	159,691
WEST PHARMACEUTICAL SVSC INC	COM	955306105	194,796	687,573	SH		DFND	4,9,10	0	322,571	365,002
WESTERN ALLIANCE BANCORP	COM	957638109	277	4,620	SH		DFND	10	0	4,620	0
WESTERN DIGITAL CORP.	COM	958102105	37,435	675,857	SH		DFND	4,9	0	475,398	200,459
WESTERN UN CO	COM	959802109	64,310	2,931,250	SH		DFND	4,9	0	1,860,390	1,070,860
WESTLAKE CHEM CORP	COM	960413102	23,027	282,193	SH		DFND	2,9	0	282,193	0
WESTLAKE CHEM PARTNERS LP	COM UNIT RP LP	960417103	27,918	1,171,077	SH		DFND	2	0	1,171,077	0
WESTROCK CO	COM	96145D105	3,913	89,914	SH		DFND	4,9,10	0	89,914	0
WEX INC	COM	96208T104	646,394	3,175,914	SH		DFND	4,10	0	3,075,895	100,019
WEYERHAEUSER CO MTN BE	COM NEW	962166104	117,769	3,512,389	SH		DFND	2,4,9,11	0	623,467	2,888,922
WHEATON PRECIOUS METALS CORP	COM	962879102	9,310	223,001	SH		DFND	4,9	0	223,001	0
WHIRLPOOL CORP	COM	963320106	17,828	98,774	SH		DFND	4,9	0	78,267	20,507
WILLIAMS COS INC	COM	969457100	53,486	2,668,163	SH		DFND	4,9	0	2,353,423	314,740
WILLIAMS SONOMA INC	COM	969904101	100,268	984,560	SH		DFND	9,10	0	928,339	56,221
WILLIS TOWERS WATSON PLC LTD	SHS	G96629103	206,398	979,753	SH		DFND	4,9,10	0	663,713	316,040
WINGSTOP INC	COM	974155103	4,319	32,581	SH		DFND	10	0	32,581	0
WIX COM LTD	SHS	M98068105	71,368	285,520	SH		DFND	4,9,10	0	147,142	138,378
WNS HLDGS LTD	SPON ADR	92932M101	132,170	1,834,416	SH		DFND	2,10	0	1,801,280	33,136
WORKDAY INC	CL A	98138H101	521,677	2,177,172	SH		DFND	4,9,10	0	1,871,869	305,303
WORLD FUEL SVCS CORP	COM	981475106	26,959	865,164	SH		DFND	2	0	865,164	0
WORLD WRESTLING ENTMT INC	CL A	98156Q108	2,618	54,476	SH		DFND	9,10	0	37,973	16,503
WP CAREY INC	COM	92936U109	4,165	59,007	SH		DFND	4,9	0	59,007	0
WSFS FINL CORP	COM	929328102	70,892	1,579,600	SH		DFND	2	0	1,579,600	0
WYNDHAM HOTELS & RESORTS INC	COM	98311A105	643	10,826	SH		DFND	10	0	10,826	0
WYNN RESORTS LTD	COM	983134107	4,062	36,004	SH		DFND	4,9	0	36,004	0
XCEL ENERGY INC	COM	98389B100	86,304	1,294,522	SH		DFND	4,9,10	0	593,401	701,121
XEROX HOLDINGS CORP	COM NEW	98421M106	236	10,162	SH		DFND	9	0	2,323	7,839
XILINX INC	COM	983919101	437,228	3,084,088	SH		DFND	4,9,10	0	2,309,472	774,616
XPEL INC	COM	98379L100	350	6,796	SH		DFND	10	0	6,796	0
XPO LOGISTICS INC	COM	983793100	23,137	194,105	SH		DFND	4,9	0	25,661	168,444
XYLEM INC	COM	98419M100	51,728	508,500	SH		DFND	4,9,10	0	508,500	0
YAMANA GOLD INC	COM	98462Y100	8,560	1,498,113	SH		DFND	4,9,11	0	1,498,113	0
YANDEX N V	SHS CLASS A	N97284108	9,120	131,059	SH		DFND	4,9	0	131,059	0
YEXT INC	COM	98585N106	77,433	4,925,737	SH		DFND	10	0	4,690,238	235,499
YUM BRANDS INC	COM	988498101	8,791	80,986	SH		DFND	4,9	0	80,986	0
YUM CHINA HLDGS INC	COM	98850P109	54,317	944,484	SH		DFND	4,10	0	944,484	0
YUM CHINA HLDGS INC	COM	98850P109	60,440	1,058,241	SH		DFND	4,9,10,12	0	881,253	176,988
ZAI LAB LTD	ADR	98887Q104	4,687	34,628	SH		DFND	9	0	34,628	0
ZEBRA TECHNOLOGIES CORPORATI	CL A	989207105	125,690	327,152	SH		DFND	4,9	0	166,155	160,997
ZENDESK INC	COM	98936J101	996,627	6,962,600	SH		DFND	4,9,10	0	6,313,212	649,388
ZILLOW GROUP INC	CL A	98954M101	14,596	107,373	SH		DFND	4,9	0	18,389	88,984
ZILLOW GROUP INC	CL C CAP STK	98954M200	102,394	788,851	SH		DFND	4,9	0	150,922	637,929
ZIMMER BIOMET HOLDINGS INC	COM	98956P102	34,350	222,930	SH		DFND	4,9	0	85,641	137,289
ZIONS BANCORPORATION N A	COM	989701107	417	9,595	SH		DFND	4	0	9,595	0
ZOETIS INC	CL A	98978V103	106,196	641,689	SH		DFND	4,9,10	0	520,986	120,703
ZOGENIX INC	COM NEW	98978L204	35,114	1,756,582	SH		DFND	10	0	1,667,669	88,913
ZOOM VIDEO COMMUNICATIONS IN	CL A	98980L101	75,951	225,159	SH		DFND	4,9	0	94,426	130,733
ZOOMINFO TECHNOLOGIES INC	COM CL A	98980F104	5,120	106,200	SH		DFND	4	0	106,200	0
ZSCALER INC	COM	98980G102	13,951	69,854	SH		DFND	4,9	0	57,432	12,422
ZTO EXPRESS CAYMAN INC	SPONSORED ADS A	98980A105	3,200	109,732	SH		DFND	9	0	109,732	0
ZYNGA INC	CL A	98986T108	29,888	3,028,178	SH		DFND	9	0	1,811,283	1,216,895